KA/EN
Register
Medicines reference
Search
Search
Active substance

Ciclosporin

Favourites

Calcineurin inhibitor. Registered in Georgia: 1 veterinary product. Forms: solution.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Ciclosporin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
5 mg/kg Dog Allergic dermatitis By mouth daily, then every 2nd day, then every 3-4 days
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Cyclavance 100 mg/ml oral solution for dogs and cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024
7 mg/kg Cat Allergic dermatitis By mouth daily, then every 2nd day, then every 3-4 days
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Cyclavance 100 mg/ml oral solution for dogs and cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024
Before use

Safety information

Known Contraindications

  • Critical
    Do not use if hypersensitive to ciclosporin or excipients.
    Sources: UK SPC
  • Critical
    Do not use with a history of, or progressive, malignant disease.
    Sources: UK SPC
  • Critical (Cat)
    Do not use in cats infected with FeLV.
    Sources: UK SPC
  • Critical (Cat)
    Do not use in cats infected with FIV.
    Sources: UK SPC
  • Warning
    No live vaccines during treatment or within two weeks before or after it.
    Sources: UK SPC
  • Warning
    Not recommended in diabetic animals: it can raise blood glucose.
    Sources: UK SPC
  • Warning
    Not recommended during pregnancy.
    Sources: UK SPC
  • Warning
    Not recommended during lactation (passes into milk).
    Sources: UK SPC
  • Warning (Dog)
    Do not use in dogs under 6 months of age or under 2 kg.
    Sources: UK SPC
  • Caution
    P-glycoprotein inhibitor: with macrocyclic lactones such as ivermectin or milbemycin, CNS toxicity is possible.
    Sources: UK SPC
  • Caution (Dog)
    Severe renal insufficiency: monitor creatinine closely; avoid other nephrotoxic drugs.
    Sources: UK SPC
Latin name
Ciclosporin
Georgian name
ციკლოსპორინი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
1 of 1 forms
Products
Cyclavance
Human medicines in Georgia
Depores, Depores Free, Ophtasis, Sandimmun, Sandimmun Neoral, Sigmasporin Microral, Sikora
Human medicines with this substance in the Georgian register of medicines (Ministry of Health), checked on 18 Oct 2026. They are human medicines, not veterinary products; strengths and forms differ.
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026
All forms and registration1

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Cyclavance 100 mg/ml, Solution

ciclosporin 100 mg/ml, oral solution for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Long-term control of chronic canine atopic dermatitis after diagnosis and control of flare factors
7.8/10
Good
vetman assessment

Cyclavance

100 mg/ml, ciclosporin 100 mg/ml, oral solution for dogs and cats
Assessed clinical scopeDog · Long-term control of chronic canine atopic dermatitis after diagnosis and control of flare factors · By mouth
Care settingVeterinary-directed long-term outpatient immunomodulatory treatment
vetman score 7.8/10 Good
Evidence confidence: High Georgia: Yes, veterinary · Verified on 18 Oct 2026

A well-supported long-term standard for correctly diagnosed canine atopic dermatitis, with meaningful immunosuppressive precautions.

Regulatory and scientific credibility8.5/10

The exact 100 mg/ml dog-and-cat solution has a current transparent UK SPC and active Georgian veterinary registration.

Clinical efficacy8.5/10

Oral ciclosporin is a consensus-supported effective standard for chronic canine atopic dermatitis, with response-based interval reduction after control.

Safety and tolerability6.5/10

Immunosuppression, malignancy, live-vaccine, diabetes, severe renal disease and reproductive restrictions require careful selection; gastrointestinal effects and infection monitoring are relevant.

Clinical practicality7.5/10

Accurate oral liquid dosing is feasible and frequency can fall after control, but initial daily treatment, food timing in dogs and long-term monitoring create a real burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use with malignant disease, within two weeks of live vaccination, or in dogs younger than six months or under 2 kg.
  • Screen and monitor for infection, diabetes and severe renal disease; avoid pregnancy and lactation and review P-glycoprotein substrate combinations.
Assessment sources
  1. VMD SPC 20242024
  2. ICADA 20152015
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Long-term control of chronic feline allergic dermatitis after diagnosis and infection screening
7.5/10
Good
vetman assessment

Cyclavance

100 mg/ml, ciclosporin 100 mg/ml, oral solution for dogs and cats
Assessed clinical scopeCat · Long-term control of chronic feline allergic dermatitis after diagnosis and infection screening · By mouth
Care settingVeterinary-directed long-term outpatient immunomodulatory treatment
vetman score 7.5/10 Good
Evidence confidence: Medium Georgia: Yes, veterinary · Verified on 18 Oct 2026

An effective labelled feline option when infection and immunosuppression risks are actively screened and monitored.

Regulatory and scientific credibility8.5/10

The exact 100 mg/ml dog-and-cat solution has a current transparent UK SPC and active Georgian veterinary registration.

Clinical efficacy8.0/10

Oral ciclosporin is an established labelled option for chronic feline allergic dermatitis, but the independent evidence base is smaller than in dogs.

Safety and tolerability6.0/10

FeLV/FIV, malignancy, live vaccines, diabetes, severe renal disease and reproduction are material restrictions; toxoplasmosis risk and infection monitoring are specifically important in cats.

Clinical practicality7.5/10

Accurate oral liquid dosing is feasible and frequency can fall after control, but initial daily treatment, food timing in dogs and long-term monitoring create a real burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in FeLV- or FIV-positive cats, malignant disease or within two weeks of live vaccination.
  • Screen and monitor for infection, diabetes and severe renal disease; avoid pregnancy and lactation and review P-glycoprotein substrate combinations.
Assessment sources
  1. VMD SPC 20242024
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Ciclosporin100 mg/ml
Formulation Type
Solution
Administration route
By mouth
Manufacturer
Virbac · France
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ციკლავანსი® 100მგ/მლ
Verified on: 18 Oct 2026
 EU Yes, veterinary
Verified on: 18 Oct 2026
 UK Yes, veterinary
№ Vm 05653/3015
Verified on: 18 Oct 2026
 US Yes, veterinary
№ ANADA 200-692
Verified on: 18 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

Trademarks belong to their owners; vetman is not affiliated with the manufacturers and receives no payment from them.

The database is protected under Chapter VII of the Law of Georgia on Copyright and Related Rights; automated or bulk copying is prohibited.

This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 29 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

Register Demo ↗