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Active substance

Hydrocortisone aceponate

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Topical glucocorticoid. Registered in Georgia: 2 veterinary products. Forms: ear drops, topical (unspecified).

Dose and use

Doses

We have no dose with a cited source for this substance yet.

Before use

Safety information

Known Contraindications

  • Critical
    Do not apply hydrocortisone aceponate to skin ulcers; in the ear, not with a perforated eardrum.
    Sources: UK SPC
  • Critical
    Do not use if hypersensitive to hydrocortisone aceponate or excipients.
    Sources: UK SPC
  • Caution
    Under 7 months: glucocorticoids slow growth; use after a benefit-risk assessment with regular checks.
    Sources: UK SPC
  • Caution
    Cushing syndrome: use only after a benefit-risk assessment. Treat no more than about a third of the body surface.
    Sources: UK SPC
  • Caution
    Pregnancy: use only after a benefit-risk assessment.
    Sources: UK SPC
  • Caution
    Lactation: use only after a benefit-risk assessment.
    Sources: UK SPC
Latin name
Hydrocortisone aceponate
Georgian name
ჰიდროკორტიზონის აცეპონატი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
2 of 2 forms
Products
Cortavance, Easotic
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026
All forms and registration2

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Cortavance 0.584 mg/ml, Topical (unspecified)

hydrocortisone aceponate 0.584 mg/ml, cutaneous spray, solution for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.4/10
Very good
vetman assessment

Cortavance

0.584 mg/ml, hydrocortisone aceponate 0.584 mg/ml, cutaneous spray, solution for dogs
Assessed clinical scopeDog · Local treatment of inflammatory and pruritic dermatoses and canine atopic dermatitis within the labelled surface-area and course limits · On the skin
Care settingVeterinary-directed outpatient dermatology care
vetman score 8.4/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · Verified on 18 Oct 2026

A strong local anti-inflammatory option for appropriately limited canine lesions, combining good evidence with lower systemic treatment burden.

Regulatory and scientific credibility8.5/10

The exact 0.584 mg/ml spray has a current 2026 UK SPC and active Georgian veterinary registration, with product-specific comparative evidence.

Clinical efficacy8.5/10

Hydrocortisone aceponate spray is guideline-supported for local canine atopic flares and has controlled evidence comparable with systemic ciclosporin in the studied setting.

Safety and tolerability8.0/10

Local delivery limits systemic exposure, but ulcers, hypersensitivity, young age, Cushing syndrome, reproduction and treatment of more than roughly one-third of body surface require caution.

Clinical practicality8.5/10

Two sprays per 10 x 10 cm once daily is precise and clinic-friendly for local disease; measuring surface area and reassessing longer atopic courses remain necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not apply to cutaneous ulcers or in hypersensitivity to hydrocortisone aceponate.
  • Treat no more than about one-third of body surface; reassess at day 14 in longer atopic-dermatitis courses.
Assessment sources
  1. VMD SPC 20262026
  2. ICADA 20152015
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Hydrocortisone aceponate0.584 mg/ml
Formulation Type
Topical (unspecified)
Administration route
On the skin
Manufacturer
Virbac · France
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კორტავანსი® 0.584 მგ/მლ
Verified on: 18 Oct 2026
 EU Yes, veterinary
№ EU/2/06/069
Verified on: 18 Oct 2026
 UK Yes, veterinary
№ Vm 05653/5001
Verified on: 18 Oct 2026
 US No
Verified on: 18 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026

Easotic, Ear drops

hydrocortisone aceponate 1.11 mg/ml + miconazole 15.1 mg/ml + gentamicin 1505 IU/ml, ear drops, suspension for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.8/10
Good
vetman assessment

Easotic

hydrocortisone aceponate 1.11 mg/ml + miconazole 15.1 mg/ml + gentamicin 1505 IU/ml, ear drops, suspension for dogs
Assessed clinical scopeDog · Labelled topical treatment of susceptible mixed bacterial and fungal otitis externa in dogs after otoscopy and ear cleaning · Into the ear
Care settingVeterinary-diagnosed outpatient otitis treatment
vetman score 7.8/10 Good
Evidence confidence: High Georgia: Yes, veterinary · Verified on 18 Oct 2026

A practical, evidence-supported short-course option for correctly diagnosed susceptible canine otitis externa; never use through a perforated tympanum.

Regulatory and scientific credibility8.5/10

The exact three-component ear suspension has a current September 2026 UK SPC and active Georgian veterinary registration, plus comparative clinical trial evidence.

Clinical efficacy8.0/10

The corticosteroid-antifungal-aminoglycoside combination addresses inflammation and susceptible mixed infection, with controlled trial support; cytology and response should determine antimicrobial fit.

Safety and tolerability6.5/10

An intact tympanum is mandatory because gentamicin is potentially ototoxic; hypersensitivity, generalised demodicosis and concurrent ototoxic treatment are hard restrictions.

Clinical practicality8.5/10

One calibrated pump per affected ear once daily for five days is simple and short, provided the canal is first cleaned, dried and examined.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Never use with a perforated tympanum; examine the ear before treatment.
  • Do not combine with other ototoxic substances or use in generalised demodicosis.
  • Use cytology and clinical response to confirm that a gentamicin-miconazole combination is justified.
Assessment sources
  1. VMD SPC 20262026
  2. Canine otitis RCT 20182018
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Hydrocortisone aceponate1.11 mg/ml Miconazole15.1 mg/ml Gentamicin1505 IU/ml
Formulation Type
Ear drops
Administration route
Into the ear
Manufacturer
Virbac · France
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ეასოტიკი®
Verified on: 18 Oct 2026
 EU Yes, veterinary
№ EU/2/08/085
Verified on: 18 Oct 2026
 UK Yes, veterinary
№ Vm 05653/5002
Verified on: 18 Oct 2026
 US Yes, veterinary
№ NADA 141-330
Verified on: 18 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 18 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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