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Active substance

Miltefosine

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Alkylphosphocholine antiprotozoal. Registered in Georgia: 1 veterinary product. Forms: solution.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Miltefosine
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
2 mg/kg Dog Canine Leishmaniosis By mouth once daily for 28 days
Source: EMA UPD SPC 2024
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Milteforan 20 mg/ml oral solution for dogs - Summary of Product Characteristics (EU decentralised procedure)
EU Union Product Database (DCP NL/V/0405/001), 2024
Before use

Safety information

Known Contraindications

  • Critical
    Do not use in dogs hypersensitive to miltefosine or excipients.
    Sources: EU SPC
  • Critical
    Do not use during pregnancy: teratogenic, foetotoxic and embryotoxic in laboratory animals.
    Sources: EU SPC
  • Critical
    Do not use during lactation.
    Sources: EU SPC
  • Warning
    Do not use in breeding animals. Must not be given by pregnant women or women who may be pregnant; wear impervious gloves.
    Sources: EU SPC
  • Caution
    Severe liver impairment: use only after a benefit-risk assessment.
    Sources: EU SPC
  • Caution
    Severe heart impairment: use only after a benefit-risk assessment.
    Sources: EU SPC
Latin name
Miltefosine
Georgian name
მილტეფოზინი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
1 of 1 forms
Products
Milteforan
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026
All forms and registration1

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Milteforan 20 mg/ml, Solution

miltefosine 20 mg/ml, oral solution for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.8/10
Good
vetman assessment

Milteforan

20 mg/ml, miltefosine 20 mg/ml, oral solution for dogs
Assessed clinical scopeDog · Labelled treatment of clinical canine leishmaniosis as part of an appropriate combination protocol · By mouth
Care settingVeterinary-directed outpatient treatment with staging, combination therapy and long-term relapse monitoring
vetman score 7.8/10 Good
Evidence confidence: High Georgia: Yes, veterinary · № 26-11 · Verified on 21 Oct 2026

A strong, evidence-supported component of combination treatment for clinical canine leishmaniosis; never use it as stand-alone curative therapy.

Regulatory and scientific credibility8.5/10

The exact 20 mg/ml oral solution has current EU product information and active Georgian veterinary registration (26-11), supported by a current specialist consensus.

Clinical efficacy8.0/10

Miltefosine 2 mg/kg daily for 28 days with allopurinol is a guideline-supported first-line combination with consistent clinical improvement, but it is not curative and monotherapy is not recommended.

Safety and tolerability7.0/10

Vomiting, diarrhoea and reduced appetite are recognised; pregnancy, lactation and breeding are contraindicated, and severe hepatic or cardiac disease requires benefit-risk assessment.

Clinical practicality7.5/10

Once-daily food-based liquid dosing is workable, but accurate weight dosing, gloves and completion of a 28-day course materially affect clinical delivery.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use during pregnancy, lactation or in breeding animals; pregnant or potentially pregnant women must not administer it.
  • Use with allopurinol in an appropriate staged protocol; monotherapy is not recommended and parasitological cure is not expected.
Assessment sources
  1. UPD SPC 20242024
  2. WAVD CanL 20252025
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Miltefosine20 mg/ml
Formulation Type
Solution
Administration route
By mouth
Manufacturer
Virbac · France
Manufacturer (register)
VIRBAC, France
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1652, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: მილტეფორანი® (მილტეფოსინა 2%)
№ 26-11
Verified on: 21 Oct 2026
 EU Yes, veterinary
№ NL/V/0405/001
Verified on: 18 Oct 2026
 UK No
Verified on: 18 Oct 2026
 US No
Verified on: 18 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 18 Oct 2026

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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