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Apoderm

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Chlortetracycline · Laboratorios Ovejero S.A.U.

1 form: aerosol / spray. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose a species; its rows are highlighted.
Form Species Dose Frequency Georgia
21.5 mg/ml, Aerosol / spray · Cat Cat 1 spray
Dogs/cats, superficial traumatic or surgical wounds contaminated by chlortetracycline-susceptible organisms: clean dirt and necrotic tissue, shake, then spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need; protect eyes, ventilate and prevent licking.
 · 1–2 times daily until complete healing, with active reassessment		 1–2 times daily until complete healing, with active reassessment Georgia Yes, veterinary
In force until 20 Jun 2029
Veterinary (National Food Agency)
In the register: აპოდერმი
№ 000591
Verified on: 22 Oct 2026
21.5 mg/ml, Aerosol / spray · Dog Dog 1 spray
Dogs/cats, superficial traumatic or surgical wounds contaminated by chlortetracycline-susceptible organisms: clean dirt and necrotic tissue, shake, then spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need; protect eyes, ventilate and prevent licking.
 · 1–2 times daily until complete healing, with active reassessment		 1–2 times daily until complete healing, with active reassessment Georgia Yes, veterinary
In force until 20 Jun 2029
Veterinary (National Food Agency)
In the register: აპოდერმი
№ 000591
Verified on: 22 Oct 2026
Details: pack, label wording, sources, registration

Apoderm 21.5 mg/ml, Aerosol / spray

chlortetracycline hydrochloride, cutaneous spray suspension
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
6.9/10
Situational / acceptable
vetman assessment

Apoderm

21.5 mg/ml, chlortetracycline hydrochloride, cutaneous spray suspension
Assessed clinical scopeDog · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 6.9/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, veterinary · № 000591 · Verified on 22 Oct 2026

A transparent, authorised topical antibiotic with a clear technique for a selected susceptible superficial wound. Its repeated daily-until-healed regimen is workable but burdensome and requires active review because independent exact-product outcomes are absent and antiseptics are usually preferred first.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.5/10

The exact label supports susceptible superficial contaminated wounds and topical antibacterial therapy is clinically plausible, but no independent outcome trial for this formulation was found. Current canine guidance prioritises antiseptics and does not establish chlortetracycline as a preferred pyoderma agent; the score does not extend to deep wounds or routine empirical pyoderma.

Safety and tolerability7.5/10

Very rare local skin reactions are labelled across target species and systemic exposure is expected to be limited. Ocular exposure, licking, sensitisation, aerosol inhalation, prolonged antibiotic use and flammable propellant remain meaningful but manageable under correct use.

Clinical practicality6.5/10

The ready-to-use 2–3-second application is simple, but one or two treatments every day until complete healing creates a meaningful at-home restraint/adherence burden and an open-ended antibiotic course that requires active review.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 15–20 cm away and spray for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Document progress and reassess the need for continued antibiotic exposure rather than treating “until healed” as an automatic unlimited course.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • Laboratory mouse, rat and rabbit studies found no maternal, fetal or teratogenic effects, but this is not a controlled exact-product dog/cat reproductive dataset. Use in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Apoderm exact2025
  2. NFA CTC sprays exact2026
  3. ISCAID canine pyoderma guideline2025
  4. AAFP/AAHA stewardship2022
  5. MSD small-animal wounds2026
  6. WSAVA acute wounds2013
  7. VMD CTC spray control2026
  8. FDA CTC index2026
  9. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
6.5/10
Situational / acceptable
vetman assessment

Apoderm

21.5 mg/ml, chlortetracycline hydrochloride, cutaneous spray suspension
Assessed clinical scopeCat · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 000591 · Verified on 22 Oct 2026

An authorised but situational feline option for a selected susceptible superficial wound. Direct cat outcomes are absent and the repeated daily aerosol regimen creates important restraint, eye-exposure and grooming-prevention burdens.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.0/10

The exact all-species label supports selected superficial feline wounds, but no direct feline outcome study was identified. General wound-care and stewardship evidence is indirect and cannot establish comparative benefit, deep-wound efficacy or routine empirical use.

Safety and tolerability7.0/10

Very rare local reactions are labelled, but direct feline safety outcomes are absent. Grooming/ingestion, eye transfer, repeated aerosol exposure and restraint burden reduce the margin; drying and prevention of licking are essential.

Clinical practicality5.5/10

Twice-possible daily aerosol restraint until complete healing, followed by drying and grooming prevention, is a substantial feline treatment burden. The technique is simple, but repeated safe execution and stewardship review are not.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 15–20 cm away and spray for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Document progress and reassess the need for continued antibiotic exposure rather than treating “until healed” as an automatic unlimited course.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • Laboratory mouse, rat and rabbit studies found no maternal, fetal or teratogenic effects, but this is not a controlled exact-product dog/cat reproductive dataset. Use in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Apoderm exact2025
  2. NFA CTC sprays exact2026
  3. AAFP/AAHA stewardship2022
  4. MSD small-animal wounds2026
  5. WSAVA acute wounds2013
  6. VMD CTC spray control2026
  7. FDA CTC index2026
  8. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Chlortetracycline21.5 mg/ml
Formulation Type
Aerosol / spray
Administration route
On the skin
Manufacturer
Laboratorios Ovejero S.A.U. · Spain
Manufacturer (register)
Laboratorios Ovejero S.A, Spain
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1059, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
In force until 20 Jun 2029
Veterinary (National Food Agency)
In the register: აპოდერმი
№ 000591
Verified on: 22 Oct 2026
 EU Yes, veterinary
№ 270 ESP
Verified on: 22 Oct 2026
 UK No
Verified on: 22 Oct 2026
 US No
Verified on: 22 Oct 2026
Controlled in Georgia
Unknown
Information not fully verified Dogs/cats, susceptible contaminated superficial traumatic or surgical wounds: clean and remove necrotic tissue, shake, spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need.
DoseSpeciesWeightRouteFrequencySource
1 spray
Dogs/cats, superficial traumatic or surgical wounds contaminated by chlortetracycline-susceptible organisms: clean dirt and necrotic tissue, shake, then spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need; protect eyes, ventilate and prevent licking.
 Cat Any weight On the skin 1–2 times daily until complete healing, with active reassessment
AEMPS Apoderm exact
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Apoderm chlortetracycline hydrochloride 21.5 mg/ml cutaneous spray - current Spanish leaflet and EU authorisation
AEMPS / EU Veterinary Medicines Information, 2025
1 spray
Dogs/cats, superficial traumatic or surgical wounds contaminated by chlortetracycline-susceptible organisms: clean dirt and necrotic tissue, shake, then spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need; protect eyes, ventilate and prevent licking.
 Dog Any weight On the skin 1–2 times daily until complete healing, with active reassessment
AEMPS Apoderm exact
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Apoderm chlortetracycline hydrochloride 21.5 mg/ml cutaneous spray - current Spanish leaflet and EU authorisation
AEMPS / EU Veterinary Medicines Information, 2025

Known Contraindications

  • Critical
    Do not use if hypersensitive to tetracyclines or excipients.
    Source: EMA Sources: Spanish SPC · EU UPD
  • Caution
    Spray: protect the eyes when treating near the head, and stop the animal licking the treated area.
    Source: EMA Sources: Spanish SPC · EU UPD

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