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Medicines reference
Product

Epixi XR

Levetiracetam · Abdi Ibrahim

2 forms: modified release (retard / SR). In force in Georgia: 2 of 2 (human register).

Forms and doses2 of 2 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Used for: Epilepsy

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
500 mg, Modified release (retard / SR) · Cat 5 kg and over Cat 5 kg and over 500 mg per animal
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Barnes Heller 2018), same substance and route. Extended-release, cats of 5 kg or more: one whole 500 mg tablet once daily. Do not crush.
· once daily
once daily Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 500მგ შემოგარსული აბი - #50
№ რ-044732
Verified on: 29 Oct 2026
500 mg, Modified release (retard / SR) · Dog Any weight Dog Any weight 30 mg/kg
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Beasley 2015), same substance and route. Extended-release: 30 mg/kg every 12 hours. Do not crush; halving the tablet does not change absorption (Mondino 2026).
· every 12 hours
every 12 hours Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 500მგ შემოგარსული აბი - #50
№ რ-044732
Verified on: 29 Oct 2026
Details: pack, label wording, sources, registration

Epixi XR 500 mg, Modified release (retard / SR)

prolonged-release tablet, human medicine
Composition / strength
Levetiracetam500 mg
Formulation Type
Modified release (retard / SR)
Administration route
By mouth
Manufacturer
Registration
Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 500მგ შემოგარსული აბი - #50
№ რ-044732
Verified on: 29 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
500 mg per animal
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Barnes Heller 2018), same substance and route. Extended-release, cats of 5 kg or more: one whole 500 mg tablet once daily. Do not crush.
Cat 5 kg and over By mouth once daily
JVIM 2018 (XR, cats)
Scientific article
A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied.
Serum levetiracetam concentrations and adverse events after multiple dose extended release levetiracetam administration to healthy cats
Journal of Veterinary Internal Medicine 32:1145-1148, 2018
From the active substance's dose: the label does not cover this species; off-label for this pack.
30 mg/kg
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Beasley 2015), same substance and route. Extended-release: 30 mg/kg every 12 hours. Do not crush; halving the tablet does not change absorption (Mondino 2026).
Dog Any weight By mouth every 12 hours
JVIM 2015 (XR, dogs)
Scientific article
A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied.
Disposition of extended release levetiracetam in normal healthy dogs after single oral dosing
Journal of Veterinary Internal Medicine 29:1348-1353, 2015
From the active substance's dose: the label does not cover this species; off-label for this pack.
750 mg, Modified release (retard / SR) · Cat 5 kg and over Cat 5 kg and over 500 mg per animal
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Barnes Heller 2018), same substance and route. Extended-release, cats of 5 kg or more: 500 mg once daily = about two thirds of this 750 mg tablet; the 500 mg extended-release tablet fits cats better. Do not crush; halving does not change absorption (Mondino 2026), smaller pieces were not studied.
· once daily
once daily Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 750მგ შემოგარსული აბი - #50
№ რ-044733
Verified on: 29 Oct 2026
750 mg, Modified release (retard / SR) · Dog Any weight Dog Any weight 30 mg/kg
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Beasley 2015), same substance and route. Extended-release: 30 mg/kg every 12 hours. Do not crush; halving the tablet does not change absorption (Mondino 2026).
· every 12 hours
every 12 hours Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 750მგ შემოგარსული აბი - #50
№ რ-044733
Verified on: 29 Oct 2026
Details: pack, label wording, sources, registration

Epixi XR 750 mg, Modified release (retard / SR)

prolonged-release tablet, human medicine
Composition / strength
Levetiracetam750 mg
Formulation Type
Modified release (retard / SR)
Administration route
By mouth
Manufacturer
Registration
Georgia Yes, human
In force until 05 Feb 2031
Human (Ministry of Health, RAMA)
In the register: ეპიქსი XR 750მგ შემოგარსული აბი - #50
№ რ-044733
Verified on: 29 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
500 mg per animal
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Barnes Heller 2018), same substance and route. Extended-release, cats of 5 kg or more: 500 mg once daily = about two thirds of this 750 mg tablet; the 500 mg extended-release tablet fits cats better. Do not crush; halving does not change absorption (Mondino 2026), smaller pieces were not studied.
Cat 5 kg and over By mouth once daily
JVIM 2018 (XR, cats)
Scientific article
A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied.
Serum levetiracetam concentrations and adverse events after multiple dose extended release levetiracetam administration to healthy cats
Journal of Veterinary Internal Medicine 32:1145-1148, 2018
From the active substance's dose: the label does not cover this species; off-label for this pack.
30 mg/kg
Off-label substance bridge: a human levetiracetam product; dose from Core levetiracetam (Beasley 2015), same substance and route. Extended-release: 30 mg/kg every 12 hours. Do not crush; halving the tablet does not change absorption (Mondino 2026).
Dog Any weight By mouth every 12 hours
JVIM 2015 (XR, dogs)
Scientific article
A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied.
Disposition of extended release levetiracetam in normal healthy dogs after single oral dosing
Journal of Veterinary Internal Medicine 29:1348-1353, 2015
From the active substance's dose: the label does not cover this species; off-label for this pack.

Known Contraindications

  • Warning
    Phenobarbital speeds levetiracetam clearance (lower peaks, faster elimination); dogs on phenobarbital may need a higher dose, guided by serum levels.
    Sources: ACVIM · JVIM
  • Warning (Dog)
    Intravenous levetiracetam: dilute and give slowly. A rapid undiluted 60 mg/kg bolus caused tachycardia, hypotension, hyperglycaemia and dull mentation in a dog.

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.