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Cefadroxil · Fatro S.p.A.

1 form: scored tablet. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Dose Frequency Georgia
200 mg, Scored tablet · Cat Cat 1 tablet per 10 kg
Exact Unacef regimen: cefadroxil 20 mg/kg PO daily, one 200 mg tablet per 10 kg. The total daily amount may be divided twice daily; in severe cases the veterinarian may double the daily amount and divide it twice daily. Continue at least 48 hours after fever or other signs resolve, but use a syndrome-specific course and planned reassessment. Equal quarters contain 50 mg and provide a 2.5 kg step; many cats below or between steps need a more suitable strength/formulation. Do not powder-divide below a quarter or invent eighths. Give with food/full stomach if needed for nausea and retain a divided piece in the original blister for no more than three days. Confirm bacterial disease: common feline lower-urinary and upper-respiratory signs are often non-bacterial.
 · once daily; the daily amount may be divided twice daily		 once daily; the daily amount may be divided twice daily Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: უნასეფი 200 მგ
№ 97-11
Verified on: 22 Oct 2026
200 mg, Scored tablet · Dog Dog 1 tablet per 10 kg
Exact Unacef regimen: cefadroxil 20 mg/kg PO daily, one 200 mg tablet per 10 kg. The total daily amount may be divided twice daily; in severe cases the veterinarian may double the daily amount and divide it twice daily. Continue at least 48 hours after fever or other signs resolve, but use a syndrome-specific course and planned reassessment. Equal quarters contain 50 mg and provide a 2.5 kg step; use a more suitable strength/formulation below or between accurate steps. Do not powder-divide below a quarter or invent eighths. Give with food/full stomach if needed for nausea and retain a divided piece in the original blister for no more than three days. Current canine pyoderma guidance uses 22-25 mg/kg q12h; do not silently transfer or improvise that higher exposure.
 · once daily; the daily amount may be divided twice daily		 once daily; the daily amount may be divided twice daily Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: უნასეფი 200 მგ
№ 97-11
Verified on: 22 Oct 2026
Details: pack, label wording, sources, registration

Unacef 200 mg, Scored tablet

cefadroxil 200 mg, quadrisected flavoured tablet for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Complete dog label: oral treatment of cefadroxil-susceptible local/systemic skin and soft-tissue, genitourinary and respiratory bacterial infections after syndrome-appropriate diagnosis and selection
7.9/10
Good
vetman assessment

Unacef

200 mg, cefadroxil 200 mg, quadrisected flavoured tablet for dogs and cats
Assessed clinical scopeDog · Complete dog label: oral treatment of cefadroxil-susceptible local/systemic skin and soft-tissue, genitourinary and respiratory bacterial infections after syndrome-appropriate diagnosis and selection · By mouth
Care settingOutpatient oral antimicrobial treatment after accurate weighing, bacterial diagnosis and susceptibility-led selection where indicated, with source control and planned reassessment
vetman score 7.9/10 Good
Evidence confidence: Medium Georgia: Yes, veterinary · № 97-11 · Verified on 22 Oct 2026

A credible, well-documented and practical first-generation cephalosporin presentation for selected susceptible dog infections. Its good score does not conceal the major canine pyoderma exposure conflict: the exact once-daily label must be reviewed rather than silently converted to the current twice-daily guideline regimen.

Regulatory and scientific credibility9.0/10

The exact 200 mg Fatro product has current transparent EU/Italian and Georgian authorisations, an official exact label/decree, and official GB class and FDA same-active oral controls. Generic legal basis is not penalised; exact-product independent outcome data are limited but identity and legal status are unusually clear.

Clinical efficacy6.5/10

Cefadroxil is a recognised first-choice systemic option for selected susceptible canine pyoderma and has older direct canine outcome evidence. The exact 20 mg/kg q24h regimen is materially below current pyoderma guidance and older trials using about 22-25 mg/kg q12h; urinary and respiratory benefit also depends strongly on diagnosis, site and susceptibility.

Safety and tolerability8.0/10

Correctly selected dogs generally tolerate cefadroxil well; exact-product GI effects, drowsiness and allergy are uncommon to very rare and pregnancy/lactation use is permitted by the label. Beta-lactam hypersensitivity, renal accumulation, microbiome/resistance effects and potential nephrotoxic combinations remain important.

Clinical practicality8.5/10

Once-daily home dosing, flavouring, food use and equal 50 mg quarters are practical for dogs fitting 2.5 kg steps. Open-ended symptom-based duration, stewardship review and three-day fragment handling add burden; patients below or between accurate steps need another strength/formulation.

Full-course cost-effectiveness-

Current Georgian full-course price was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Scope boundary: this score covers the complete authorised susceptible bacterial dog scope. It does not endorse prophylaxis, undiagnosed non-bacterial disease, every organism without susceptibility, cats, another strength or another jurisdiction's regimen.
  • Dog pyoderma exposure conflict: exact Unacef is 20 mg/kg q24h, while ISCAID 2025 recommends cefadroxil 22-25 mg/kg q12h. Do not silently double or rewrite this product's regimen; review adequacy and choose an authorised or explicitly justified strategy.
  • Stewardship: surface and most superficial canine pyoderma should receive topical antiseptic-first care. Reserve systemic treatment for appropriate deep disease or selected topical failure/non-feasibility, with cytology and culture/susceptibility when indicated.
  • Exact standard dose: 20 mg/kg PO daily, one 200 mg tablet/10 kg. The daily total may be divided; severe cases may be doubled only by the veterinarian and divided twice daily. Do not powder-divide below a quarter, invent eighths or transfer FDA Cefa-Drops dosing.
  • Equal quarters contain 50 mg and provide 2.5 kg steps. Weigh accurately and choose another strength/formulation below or between reliable steps. Return a divided piece to the original blister and use it within three days.
  • The label's “at least 48 hours after signs resolve” is not a universal course. Use syndrome-specific duration, source control and planned response review; do not treat subclinical bacteriuria or extend blindly after failure.
  • Do not use with known cephalosporin or other beta-lactam hypersensitivity. Stop and treat urgently for facial swelling, dyspnoea, generalised rash or other acute allergy; exact-label allergy is very rare but can be serious.
  • Nausea/vomiting, diarrhoea and drowsiness are reported. Giving on a full stomach can reduce nausea/vomiting; persistent GI signs, deterioration or no response requires diagnosis, susceptibility and source-control review.
  • Do not combine with bacteriostatic antibiotics. Review renal impairment and avoid or closely justify concurrent aminoglycosides, polypeptide antibiotics or furosemide because first-generation cephalosporin nephrotoxicity can increase.
  • The exact label permits pregnancy/lactation, but this is not proof of zero risk. Keep flavoured tablets away from animals/children; people with cephalosporin hypersensitivity should avoid contact and wash hands after handling.
Assessment sources
  1. EU SPC 20162016
  2. Unacef GE register2026
  3. Unacef Italian decree2016
  4. Cefa-Drops FDA FOI1988
  5. Petalexin VMD2022
  6. ISCAID 20252025
  7. ISCAID urinary 20192019
  8. ISCAID 20172017
  9. Canine cefadroxil pyoderma study1988
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Complete cat label: oral treatment of cefadroxil-susceptible local/systemic skin and soft-tissue, genitourinary and respiratory bacterial infections after excluding common non-bacterial differentials
7.8/10
Good
vetman assessment

Unacef

200 mg, cefadroxil 200 mg, quadrisected flavoured tablet for dogs and cats
Assessed clinical scopeCat · Complete cat label: oral treatment of cefadroxil-susceptible local/systemic skin and soft-tissue, genitourinary and respiratory bacterial infections after excluding common non-bacterial differentials · By mouth
Care settingOutpatient oral antimicrobial treatment after accurate weighing, confirmation of bacterial disease and source control, with culture/susceptibility and planned reassessment where indicated
vetman score 7.8/10 Good
Evidence confidence: Medium Georgia: Yes, veterinary · № 97-11 · Verified on 22 Oct 2026

A well-documented oral cefadroxil presentation with useful direct feline skin/soft-tissue evidence and a regimen close to that evidence. Its good score is conditional on confirming bacterial disease, respecting spectrum/resistance and choosing a smaller presentation when the 50 mg quarter cannot dose the cat accurately.

Regulatory and scientific credibility9.0/10

The exact 200 mg Fatro product has current transparent EU/Italian and Georgian authorisations and official exact documentation. FDA same-active dog/cat oral data and a current GB dog/cat first-generation cephalosporin control strengthen applicability without being misrepresented as exact-brand authorisations.

Clinical efficacy7.0/10

The exact 20 mg/kg once-daily regimen is close to FDA field and later controlled feline skin/soft-tissue evidence using about 22 mg/kg once daily, and respiratory consensus lists 22 mg/kg q24h for selected secondary bacterial URI. Broad urinary/respiratory claims remain less direct, resistance matters, and common feline LUT/URI presentations are often non-bacterial.

Safety and tolerability7.5/10

Most cats tolerate cefadroxil with infrequent GI effects, drowsiness or allergy, and the exact label permits pregnancy/lactation. Safety is reduced modestly by a published probable cefadroxil-associated feline SJS/TEN case plus beta-lactam hypersensitivity, renal accumulation and nephrotoxic-combination concerns.

Clinical practicality7.5/10

Once-daily use, food administration and equal quarters are workable, but each 50 mg quarter is a 2.5 kg step: many cats below or between steps need a smaller strength or liquid rather than powder division below a quarter. Palatability is not assured in an individual cat, and three-day fragment handling plus response review remain relevant.

Full-course cost-effectiveness-

Current Georgian full-course price was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Scope boundary: this score covers the complete authorised susceptible bacterial cat scope. It does not endorse prophylaxis, undiagnosed lower-urinary or respiratory signs, every organism without susceptibility, dogs, another strength or another jurisdiction's regimen.
  • Confirm bacterial disease: many feline lower-urinary signs are non-bacterial and acute upper-respiratory disease is commonly viral. Do not treat subclinical bacteriuria or use cefadroxil as a default for uncomplicated viral URI.
  • Spectrum boundary: cefadroxil is ineffective against Bordetella bronchiseptica, Mycoplasma spp., Chlamydia felis and Enterococcus spp.; Gram-negative resistance can be regionally common. Use culture/susceptibility when indicated and control wounds/abscesses.
  • Exact standard dose: 20 mg/kg PO daily, one 200 mg tablet/10 kg. The daily total may be divided; severe cases may be doubled only by the veterinarian and divided twice daily. Do not powder-divide below a quarter, invent eighths or transfer FDA Cefa-Drops dosing.
  • Equal quarters contain 50 mg and provide 2.5 kg steps. Many cats below or between reliable steps need a smaller strength or liquid; flavouring does not guarantee acceptance. Use a divided piece within three days.
  • The label's “at least 48 hours after signs resolve” is not a universal course. Use syndrome-specific duration, source control and planned reassessment; persistent signs need diagnostic review rather than blind continuation.
  • Do not use with known cephalosporin or other beta-lactam hypersensitivity. Stop and treat urgently for facial swelling, dyspnoea or acute generalised allergy.
  • Rare but severe cutaneous stop sign: a published cat case assessed cefadroxil as a very probable cause of SJS/TEN. Stop urgently for mucocutaneous erosions, blistering, epidermal detachment, fever or rapidly spreading painful lesions.
  • Do not combine with bacteriostatic antibiotics. Review renal impairment and avoid or closely justify concurrent aminoglycosides, polypeptide antibiotics or furosemide because first-generation cephalosporin nephrotoxicity can increase.
  • Nausea/vomiting, diarrhoea and drowsiness are reported; giving on a full stomach may help. The label permits pregnancy/lactation but does not prove zero risk. Keep flavoured tablets away from animals/children and wash hands.
Assessment sources
  1. EU SPC 20162016
  2. Unacef GE register2026
  3. Unacef Italian decree2016
  4. Cefa-Drops FDA FOI1988
  5. Petalexin VMD2022
  6. ISCAID urinary 20192019
  7. ISCAID 20172017
  8. Feline cefadroxil controlled trial2009
  9. Feline cefadroxil SJS/TEN2017
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Cefadroxil200 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
Fatro S.p.A. · Italy
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: უნასეფი 200 მგ
№ 97-11
Verified on: 22 Oct 2026
 EU Yes, veterinary
№ 104879034; 104879046
Verified on: 22 Oct 2026
 UK No
Verified on: 22 Oct 2026
 US No
Verified on: 22 Oct 2026
Controlled in Georgia
Unknown
Information not fully verified Prescription-only first-generation cephalosporin. Exact label: 20 mg/kg PO daily, one 200 mg tablet/10 kg; daily amount may be divided twice daily and severe cases may be doubled only by the veterinarian. Equal quarters provide 50 mg/2.5 kg steps. Continue at least 48 hours after signs resolve, but use a modern syndrome-specific plan, culture/susceptibility where indicated and response review. Give with food/full stomach if needed; use a divided piece within three days.
DoseSpeciesWeightRouteFrequencySource
1 tablet per 10 kg
Exact Unacef regimen: cefadroxil 20 mg/kg PO daily, one 200 mg tablet per 10 kg. The total daily amount may be divided twice daily; in severe cases the veterinarian may double the daily amount and divide it twice daily. Continue at least 48 hours after fever or other signs resolve, but use a syndrome-specific course and planned reassessment. Equal quarters contain 50 mg and provide a 2.5 kg step; many cats below or between steps need a more suitable strength/formulation. Do not powder-divide below a quarter or invent eighths. Give with food/full stomach if needed for nausea and retain a divided piece in the original blister for no more than three days. Confirm bacterial disease: common feline lower-urinary and upper-respiratory signs are often non-bacterial.
 Cat Any weight By mouth once daily; the daily amount may be divided twice daily
EU SPC 2016
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Unacef 200 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2016
1 tablet per 10 kg
Exact Unacef regimen: cefadroxil 20 mg/kg PO daily, one 200 mg tablet per 10 kg. The total daily amount may be divided twice daily; in severe cases the veterinarian may double the daily amount and divide it twice daily. Continue at least 48 hours after fever or other signs resolve, but use a syndrome-specific course and planned reassessment. Equal quarters contain 50 mg and provide a 2.5 kg step; use a more suitable strength/formulation below or between accurate steps. Do not powder-divide below a quarter or invent eighths. Give with food/full stomach if needed for nausea and retain a divided piece in the original blister for no more than three days. Current canine pyoderma guidance uses 22-25 mg/kg q12h; do not silently transfer or improvise that higher exposure.
 Dog Any weight By mouth once daily; the daily amount may be divided twice daily
EU SPC 2016
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Unacef 200 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2016

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 23 Oct 2026

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