Register
Medicines reference
Active substance

Atenolol

Beta-1 selective adrenoceptor blocker. Registered in Georgia: 5 human medicines. Forms: tablet.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Atenolol
Before use

Safety information

Known Contraindications

  • Critical
    Atenolol is contraindicated in sinus bradycardia, heart block greater than first degree, cardiogenic shock, and overt cardiac failure.
    Sources: FDA
  • Critical
    Heart failure: the label contraindicates atenolol in overt (decompensated) heart failure. In dogs and cats with stable congestive heart failure or dilated cardiomyopathy, start with a low dose and increase it slowly.
    Sources: FDA · MSD Vet Manual
  • Critical
    Known hypersensitivity to atenolol or any product component is a contraindication.
    Sources: FDA
  • Warning
    undergoes little or no metabolism by the liver, and the absorbed portion is eliminated primarily by renal excretion.
    Sources: FDA
  • Warning
    Abrupt discontinuation should be avoided; if cessation is indicated, titrating down gradually is recommended.
    Sources: MSD Vet Manual
  • Caution
    Asthma or airway disease: atenolol is beta-1 selective, so its bronchospasm risk is lower than that of propranolol, which MSD says should be avoided in dogs and cats with primary respiratory disease. Selectivity falls at higher doses: use with caution.
    Sources: MSD Vet Manual
  • Caution
    Adverse effects include myocardial depression, bradycardia (sinus and AV block), and hypotension.
    Sources: MSD Vet Manual

Known Drug Interactions

  • Contraindicated Atenolol + Xylometazoline
    Do not combine xylometazoline with beta blockers because additive cardiovascular effects may occur.
    Recommendation: Do not administer concurrently.
  • Minor warning Pimobendan + Atenolol
    Beta-adrenergic blockers such as propranolol or atenolol and calcium-channel blockers such as verapamil or diltiazem can reduce the positive inotropic effect of pimobendan.
    Recommendation: Monitor clinical response.
    Sources: Vetmedin SPC
  • Minor warning Atenolol + Methimazole
    A reduction in dose of certain drugs (β-adrenergic blocking agents, digitalis glycosides, and theophylline) may be needed when the patient becomes euthyroid.
    Recommendation: Reassess the dose once euthyroidism is achieved.
    Sources: FDA
Latin name
Atenolol
Georgian name
ატენოლოლი
Authorisation status
Human medicine, cascade use
No veterinary authorisation was found in any register checked. Veterinary use is off-label, under the prescribing cascade.
Registered in Georgia
5 of 5 forms
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration5

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Atenolol-Denk 50 mg, Tablet

film-coated tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control
6.3/10
Situational / acceptable
vetman assessment

Atenolol-Denk

50 mg, film-coated tablet, human medicine
Assessed clinical scopeDog · Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 6.3/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-038897 · Verified on 16 Oct 2026 Off-label use

A situational canine beta-1 blocker with recognised rate-control use and important disease-specific evidence limits. Verified 25 and 50 mg units are workable for selected medium or large dogs, but smaller or fine-titrated doses require a more suitable formulation.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.5/10

Atenolol produces measurable beta-1 blockade and remains a recognised veterinary class-II option, but effect depends on disease and regimen. A randomized Boxer trial found atenolol alone ineffective while mexiletine-atenolol helped; severe subaortic-stenosis cohorts found no survival benefit, and controlled pharmacodynamics support dosing more often than once daily for sustained blockade.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality6.0/10

The scored 50 mg tablet provides verified 25 mg or 50 mg units, covering selected medium and large dogs better than a whole-only presentation. It still cannot support small-dog or fine dose adjustment, and twice-daily monitored titration remains necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM
5.3/10
Weak evidence support
vetman assessment

Atenolol-Denk

50 mg, film-coated tablet, human medicine
Assessed clinical scopeCat · Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 5.3/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-038897 · Verified on 16 Oct 2026 Off-label use

The ingredient has a selective feline role, but this human tablet is a poor dose-delivery match: its smallest verified 25 mg unit is two to four times the usual 6.25-12.5 mg feline dose. Do not treat incidental asymptomatic HCM routinely or improvise an unmeasured powder fraction.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.0/10

Atenolol reliably lowers heart rate and dynamic outflow velocity in selected cats, and consensus allows it for severe DLVOTO or certain arrhythmias. Evidence does not support routine asymptomatic HCM treatment: a five-year cohort found no survival benefit, and the guideline rates key recommendations as low-level evidence.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality1.0/10

The usual sourced feline dose is 6.25-12.5 mg per cat, but the smallest verified unit from this presentation is 25 mg. Crushing does not make informal powder division accurate; a lower-strength or validated patient-specific compound is normally required.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Atenolol50 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Denk Pharma · Germany
Registration
Georgia Yes, human
In force until 22 Aug 2028
Human (Ministry of Health, RAMA)
In the register: ატენოლოლ-დენკი 50 მგ, აბი
№ რ-038897
Verified on: 16 Oct 2026
EU Yes, human
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Atenolol Borisov 50 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control
6.1/10
Situational / acceptable
vetman assessment

Atenolol Borisov

50 mg, tablet, human medicine
Assessed clinical scopeDog · Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-040566 · Verified on 16 Oct 2026 Off-label use

A situational canine beta-1 blocker with recognised rate-control use and important disease-specific evidence limits. Verified 25 and 50 mg units are workable for selected medium or large dogs, but smaller or fine-titrated doses require a more suitable formulation.

Regulatory and scientific credibility6.0/10

The exact human tablet has a sourced current Georgian registration, identifiable manufacturer, strength and verified split rule, but exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match. It has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Atenolol produces measurable beta-1 blockade and remains a recognised veterinary class-II option, but effect depends on disease and regimen. A randomized Boxer trial found atenolol alone ineffective while mexiletine-atenolol helped; severe subaortic-stenosis cohorts found no survival benefit, and controlled pharmacodynamics support dosing more often than once daily for sustained blockade.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality6.0/10

The scored 50 mg tablet provides verified 25 mg or 50 mg units, covering selected medium and large dogs better than a whole-only presentation. It still cannot support small-dog or fine dose adjustment, and twice-daily monitored titration remains necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM
5.2/10
Weak evidence support
vetman assessment

Atenolol Borisov

50 mg, tablet, human medicine
Assessed clinical scopeCat · Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 5.2/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-040566 · Verified on 16 Oct 2026 Off-label use

The ingredient has a selective feline role, but this human tablet is a poor dose-delivery match: its smallest verified 25 mg unit is two to four times the usual 6.25-12.5 mg feline dose. Do not treat incidental asymptomatic HCM routinely or improvise an unmeasured powder fraction.

Regulatory and scientific credibility6.0/10

The exact human tablet has a sourced current Georgian registration, identifiable manufacturer, strength and verified split rule, but exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match. It has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.0/10

Atenolol reliably lowers heart rate and dynamic outflow velocity in selected cats, and consensus allows it for severe DLVOTO or certain arrhythmias. Evidence does not support routine asymptomatic HCM treatment: a five-year cohort found no survival benefit, and the guideline rates key recommendations as low-level evidence.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality1.0/10

The usual sourced feline dose is 6.25-12.5 mg per cat, but the smallest verified unit from this presentation is 25 mg. Crushing does not make informal powder division accurate; a lower-strength or validated patient-specific compound is normally required.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Atenolol50 mg
Formulation Type
Tablet
Administration route
By mouth
Registration
Georgia Yes, human
In force until 26 Mar 2029
Human (Ministry of Health, RAMA)
In the register: ატენოლოლი ბორისოვი 50 მგ, აბი
№ რ-040566
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Atenolol Gama 25 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control
6.1/10
Situational / acceptable
vetman assessment

Atenolol Gama

25 mg, tablet, human medicine
Assessed clinical scopeDog · Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035254 · Verified on 16 Oct 2026 Off-label use

A situational canine beta-1 blocker with recognised rate-control use and important disease-specific evidence limits. This whole-only 25 mg form can suit selected medium or large dogs, but not small dogs or fine titration; confirm the rhythm and haemodynamic goal and monitor response.

Regulatory and scientific credibility6.0/10

The exact human tablet has a sourced current Georgian registration, identifiable manufacturer, strength and verified split rule, but exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match. It has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Atenolol produces measurable beta-1 blockade and remains a recognised veterinary class-II option, but effect depends on disease and regimen. A randomized Boxer trial found atenolol alone ineffective while mexiletine-atenolol helped; severe subaortic-stenosis cohorts found no survival benefit, and controlled pharmacodynamics support dosing more often than once daily for sustained blockade.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality5.5/10

This whole-only 25 mg tablet fits selected medium or large dogs within the broad weight-based range, but it cannot support smaller doses or fine titration. Twice-daily treatment and pulse, blood-pressure and ECG reassessment add a meaningful but manageable burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 25 mg tablet is recorded as whole-only. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM
5.2/10
Weak evidence support
vetman assessment

Atenolol Gama

25 mg, tablet, human medicine
Assessed clinical scopeCat · Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 5.2/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-035254 · Verified on 16 Oct 2026 Off-label use

The ingredient has a selective feline role, but this human tablet is a poor dose-delivery match: its smallest verified 25 mg unit is two to four times the usual 6.25-12.5 mg feline dose. Do not treat incidental asymptomatic HCM routinely or improvise an unmeasured powder fraction.

Regulatory and scientific credibility6.0/10

The exact human tablet has a sourced current Georgian registration, identifiable manufacturer, strength and verified split rule, but exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match. It has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.0/10

Atenolol reliably lowers heart rate and dynamic outflow velocity in selected cats, and consensus allows it for severe DLVOTO or certain arrhythmias. Evidence does not support routine asymptomatic HCM treatment: a five-year cohort found no survival benefit, and the guideline rates key recommendations as low-level evidence.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality1.0/10

The usual sourced feline dose is 6.25-12.5 mg per cat, but the smallest verified unit from this presentation is 25 mg. Crushing does not make informal powder division accurate; a lower-strength or validated patient-specific compound is normally required.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 25 mg tablet is recorded as whole-only. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Atenolol25 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Registration
Georgia Yes, human
In force until 18 May 2027
Human (Ministry of Health, RAMA)
In the register: ატენოლოლი გამა 25 მგ, აბი
№ რ-035254
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Atenolol Sopharma 25 mg, Tablet

film-coated tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control
6.2/10
Situational / acceptable
vetman assessment

Atenolol Sopharma

25 mg, film-coated tablet, human medicine
Assessed clinical scopeDog · Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035479 · Verified on 16 Oct 2026 Off-label use

A situational canine beta-1 blocker with recognised rate-control use and important disease-specific evidence limits. This whole-only 25 mg form can suit selected medium or large dogs, but not small dogs or fine titration; confirm the rhythm and haemodynamic goal and monitor response.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.5/10

Atenolol produces measurable beta-1 blockade and remains a recognised veterinary class-II option, but effect depends on disease and regimen. A randomized Boxer trial found atenolol alone ineffective while mexiletine-atenolol helped; severe subaortic-stenosis cohorts found no survival benefit, and controlled pharmacodynamics support dosing more often than once daily for sustained blockade.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality5.5/10

This whole-only 25 mg tablet fits selected medium or large dogs within the broad weight-based range, but it cannot support smaller doses or fine titration. Twice-daily treatment and pulse, blood-pressure and ECG reassessment add a meaningful but manageable burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 25 mg tablet is recorded as whole-only. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM
5.3/10
Weak evidence support
vetman assessment

Atenolol Sopharma

25 mg, film-coated tablet, human medicine
Assessed clinical scopeCat · Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 5.3/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-035479 · Verified on 16 Oct 2026 Off-label use

The ingredient has a selective feline role, but this human tablet is a poor dose-delivery match: its smallest verified 25 mg unit is two to four times the usual 6.25-12.5 mg feline dose. Do not treat incidental asymptomatic HCM routinely or improvise an unmeasured powder fraction.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.0/10

Atenolol reliably lowers heart rate and dynamic outflow velocity in selected cats, and consensus allows it for severe DLVOTO or certain arrhythmias. Evidence does not support routine asymptomatic HCM treatment: a five-year cohort found no survival benefit, and the guideline rates key recommendations as low-level evidence.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality1.0/10

The usual sourced feline dose is 6.25-12.5 mg per cat, but the smallest verified unit from this presentation is 25 mg. Crushing does not make informal powder division accurate; a lower-strength or validated patient-specific compound is normally required.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 25 mg tablet is recorded as whole-only. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Atenolol25 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Sopharma · Bulgaria
Registration
Georgia Yes, human
In force until 07 Jun 2027
Human (Ministry of Health, RAMA)
In the register: ატენოლოლი სოფარმა 25 მგ, აბი
№ რ-035479
Verified on: 16 Oct 2026
EU Yes, human
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Atenolol Sopharma 50 mg, Tablet

film-coated tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control
6.3/10
Situational / acceptable
vetman assessment

Atenolol Sopharma

50 mg, film-coated tablet, human medicine
Assessed clinical scopeDog · Off-label oral atenolol as veterinary-selected beta-1 blockade for selected canine tachyarrhythmias or clinically important sympathetic rate control · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 6.3/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035480 · Verified on 16 Oct 2026 Off-label use

A situational canine beta-1 blocker with recognised rate-control use and important disease-specific evidence limits. Verified 25 and 50 mg units are workable for selected medium or large dogs, but smaller or fine-titrated doses require a more suitable formulation.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.5/10

Atenolol produces measurable beta-1 blockade and remains a recognised veterinary class-II option, but effect depends on disease and regimen. A randomized Boxer trial found atenolol alone ineffective while mexiletine-atenolol helped; severe subaortic-stenosis cohorts found no survival benefit, and controlled pharmacodynamics support dosing more often than once daily for sustained blockade.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality6.0/10

The scored 50 mg tablet provides verified 25 mg or 50 mg units, covering selected medium and large dogs better than a whole-only presentation. It still cannot support small-dog or fine dose adjustment, and twice-daily monitored titration remains necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM
5.3/10
Weak evidence support
vetman assessment

Atenolol Sopharma

50 mg, film-coated tablet, human medicine
Assessed clinical scopeCat · Off-label oral atenolol for selected feline tachyarrhythmias or severe dynamic left-ventricular outflow obstruction; not routine treatment of asymptomatic HCM · By mouth
Care settingSpecialist-guided or closely monitored outpatient cardiac treatment after ECG, blood pressure and haemodynamic assessment, with slow titration and scheduled reassessment
vetman score 5.3/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-035480 · Verified on 16 Oct 2026 Off-label use

The ingredient has a selective feline role, but this human tablet is a poor dose-delivery match: its smallest verified 25 mg unit is two to four times the usual 6.25-12.5 mg feline dose. Do not treat incidental asymptomatic HCM routinely or improvise an unmeasured powder fraction.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, with an identifiable manufacturer, strength and verified split rule. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy6.0/10

Atenolol reliably lowers heart rate and dynamic outflow velocity in selected cats, and consensus allows it for severe DLVOTO or certain arrhythmias. Evidence does not support routine asymptomatic HCM treatment: a five-year cohort found no survival benefit, and the guideline rates key recommendations as low-level evidence.

Safety and tolerability6.0/10

Predictable beta blockade is clinically useful but can cause bradycardia, hypotension, AV block, exercise intolerance or worsening low-output and decompensated heart failure. These exact human tablets lack target-animal safety dossiers; renal clearance, bronchospasm risk, metabolic masking and interacting cardiac drugs require selection and monitoring.

Clinical practicality1.0/10

The usual sourced feline dose is 6.25-12.5 mg per cat, but the smallest verified unit from this presentation is 25 mg. Crushing does not make informal powder division accurate; a lower-strength or validated patient-specific compound is normally required.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in clinically important sinus bradycardia, sick-sinus syndrome or second- or third-degree AV block without pacing; confirm rhythm before treatment.
  • Do not initiate during cardiogenic shock, acute decompensated heart failure or other unstable low-output states. Stabilise first and use only after an individual haemodynamic assessment.
  • Diltiazem, verapamil, digoxin, amiodarone, sotalol and other rate-slowing or negative-inotropic drugs can add bradycardia, AV block, hypotension or contractility depression; combine only with ECG and haemodynamic oversight.
  • Atenolol is substantially renally eliminated. Review kidney function, hydration and concurrent renally cleared drugs, and reconsider dose or interval if clearance is reduced.
  • Beta-1 selectivity is not absolute. Use cautiously in bronchospastic disease and monitor for new cough, wheeze or respiratory effort, especially at higher exposure.
  • Beta blockade may mask tachycardia from hypoglycaemia or hyperthyroidism and can alter insulin response. Monitor vulnerable diabetic, fasting, neonatal or endocrine patients rather than relying on heart rate alone.
  • Start low, titrate to the documented rhythm or haemodynamic target, and monitor pulse, blood pressure, ECG, perfusion, exercise tolerance and heart-failure signs. Do not stop chronic treatment abruptly; taper under veterinary direction.
  • This exact 50 mg tablet is verified only to a 25 mg half. Do not estimate a smaller dog or feline dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated patient-specific compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Atenolol50 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Sopharma · Bulgaria
Registration
Georgia Yes, human
In force until 07 Jun 2027
Human (Ministry of Health, RAMA)
In the register: ატენოლოლი სოფარმა 50 მგ, აბი
№ რ-035480
Verified on: 16 Oct 2026
EU Yes, human
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.