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Active substance

Calcium chloride

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Electrolyte. No registration in force in Georgia. Forms: solution.

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Dose and use

Doses

We have no dose with a cited source for this substance yet.

Before use

Safety information

Known Drug Interactions

  • Minor warning Oxytetracycline + Calcium chloride
    Do not mix oxytetracycline with calcium-containing infusion solutions because they are physically incompatible.
    Recommendation: Do not mix oxytetracycline with lactated Ringer solution or run them through the same line.
Latin name
Calcium chloride
Georgian name
კალციუმის ქლორიდი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
0 of 1 forms
Products
Ringer lactate SEEM
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration1

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Ringer lactate SEEM, Solution

solution for infusion, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog IV buffered-isotonic crystalloid resuscitation of confirmed hypovolaemia
6.6/10
Situational / acceptable
vetman assessment

Ringer lactate SEEM

solution for infusion, human medicine
Assessed clinical scopeDog · IV buffered-isotonic crystalloid resuscitation of confirmed hypovolaemia · Intravenous
Care settingEmergency/critical-care IV bolus with perfusion reassessment after every 15–20 mL/kg over 15–30 min; not routine fluid loading of a euvolaemic patient.
vetman score 6.6/10 Situational / acceptable
Evidence confidence: Medium Georgia: No longer listed · № რ-032747, რ-032746 · Verified on 22 Oct 2026 Off-label use

A standard class-level resuscitation fluid with a credible dog regimen, but this exact human presentation has expired Georgian authorisation and no recognised veterinary dossier. Use only for true hypovolaemia, in small reassessed boluses—not a fixed shock-volume target.

Regulatory and scientific credibility4.5/10

Exact composition and manufacturer instruction are verifiable and a 2022 Uzbek state register corroborates identity and historical legal-market status, but the Georgian certificates expired. The reviewed EU/GB/US searches did not establish current exact-product status and lack the documented same-endpoint positive controls required to prove non-authorisation; veterinary use is off-label and no recognised-regulator veterinary dossier for this presentation was verified.

Clinical efficacy8.0/10

Buffered isotonic crystalloids are a guideline-standard replacement option for the assessed role; benefit is well established at class level, while exact-product veterinary outcome trials are absent and response depends on diagnosis, volume and reassessment.

Safety and tolerability6.5/10

Predictable class risks are manageable with selection and monitoring, but overload, pulmonary oedema, electrolyte/acid-base shifts and calcium-containing admixture incompatibilities can be serious; exact-product veterinary pharmacovigilance is limited.

Clinical practicality8.0/10

A ready-to-infuse 250/500 mL solution is workable in emergency care with IV access and a pump or calibrated set; benefit depends on rapid reassessment, cumulative-volume tracking, asepsis and an alternative line for incompatible infusions.

Full-course cost-effectiveness-

A current Georgian exact-pack price and patient-specific treatment cost were not verified; price is excluded from the denominator.

Important safety and use flags

  • Stop the infusion and urgently reassess restlessness, tachypnoea/increased effort, moist lung sounds, cough, nasal discharge, oedema, rapid weight gain or other suspected fluid overload/pulmonary oedema.
  • Do not use as routine volume loading in a euvolaemic patient or with existing overhydration/pulmonary oedema. Exact SEEM also lists alkalosis, severe hepatic dysfunction, acute renal failure, lactic acidosis and hypertonic dehydration as contraindications.
  • Individualise fluid type, bolus/rate and cumulative volume from perfusion, weight, urine output, blood pressure, respiratory/lung findings, electrolytes, acid-base state, concurrent enteral/drug fluids and ongoing losses; risk is higher in cats and cardiac/renal patients.
  • Do not mix with phosphate- or carbonate-containing solutions or use as a routine drug diluent/carrier. Verify exact admixture and Y-site compatibility before adding or co-infusing any medicine; use a separate line when compatibility is unknown.
  • Because the solution contains calcium, do not co-infuse blood through the same set unless an exact institutional compatibility protocol explicitly permits it; do not add calcium-chelating or otherwise incompatible medicines.
  • Review potassium supplements, potassium-sparing diuretics and ACE inhibitors for hyperkalaemia risk. Calcium may increase cardiac-glycoside toxicity; use only with deliberate monitoring and verified compatibility.
  • This is a human SEEM presentation used off-label in dogs and cats. Exact-product veterinary sterility/quality dossier, outcome trials and recognised-regulator pharmacovigilance were not located; class evidence and a composition-near authorised veterinary comparator support clinical transfer, not exact-product equivalence.
  • Lactated Ringer's is a replacement crystalloid, not automatically the right long-term maintenance fluid. Prolonged isotonic use may cause sodium derangement and hypokalaemia; reassess fluid composition when the patient is euvolaemic.
  • Use aseptic IV technique and calibrated delivery; inspect container integrity and solution clarity, never use a leaking/cloudy/particulate container, dedicate opened product to one patient and discard unused contents according to the exact pack instruction.
Assessment sources
  1. SEEM exact instruction2026
  2. UZ exact register2022
  3. GE SEEM audit2026
  4. SEEM EU-GB-US checks2026
  5. AAHA fluid guideline2024
  6. AAHA fluid controversies2024
  7. Veterinary Hartmann comparator2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Dog IV replacement of calculated extracellular dehydration deficit and ongoing losses
6.8/10
Situational / acceptable
vetman assessment

Ringer lactate SEEM

solution for infusion, human medicine
Assessed clinical scopeDog · IV replacement of calculated extracellular dehydration deficit and ongoing losses · Intravenous
Care settingHospital IV rehydration: calculate deficit and replace over 12–24 h, add measured ongoing losses and oral/enteral/medication fluids, and reassess weight, hydration, urine output and chemistry.
vetman score 6.8/10 Situational / acceptable
Evidence confidence: Medium Georgia: No longer listed · № რ-032747, რ-032746 · Verified on 22 Oct 2026 Off-label use

A useful buffered replacement fluid for calculated canine dehydration when composition matches the patient. It should not become an unmonitored long-term maintenance default, and exact SEEM quality/regulatory support remains weaker than recognised veterinary alternatives.

Regulatory and scientific credibility4.5/10

Exact composition and manufacturer instruction are verifiable and a 2022 Uzbek state register corroborates identity and historical legal-market status, but the Georgian certificates expired. The reviewed EU/GB/US searches did not establish current exact-product status and lack the documented same-endpoint positive controls required to prove non-authorisation; veterinary use is off-label and no recognised-regulator veterinary dossier for this presentation was verified.

Clinical efficacy8.0/10

Buffered isotonic crystalloids are a guideline-standard replacement option for the assessed role; benefit is well established at class level, while exact-product veterinary outcome trials are absent and response depends on diagnosis, volume and reassessment.

Safety and tolerability7.0/10

Slower deficit replacement is generally controllable with serial assessment, but overload and electrolyte/acid-base shifts remain possible, especially with renal/cardiac/hepatic disease or prolonged use as maintenance; exact-product veterinary surveillance is limited.

Clinical practicality8.0/10

Ready-to-infuse packs fit hospital rehydration, but correct use requires deficit and ongoing-loss calculations, infusion control, intake/output accounting, repeat examination and chemistry-guided adjustment rather than a default hourly rate.

Full-course cost-effectiveness-

A current Georgian exact-pack price and patient-specific treatment cost were not verified; price is excluded from the denominator.

Important safety and use flags

  • Stop the infusion and urgently reassess restlessness, tachypnoea/increased effort, moist lung sounds, cough, nasal discharge, oedema, rapid weight gain or other suspected fluid overload/pulmonary oedema.
  • Do not use as routine volume loading in a euvolaemic patient or with existing overhydration/pulmonary oedema. Exact SEEM also lists alkalosis, severe hepatic dysfunction, acute renal failure, lactic acidosis and hypertonic dehydration as contraindications.
  • Individualise fluid type, bolus/rate and cumulative volume from perfusion, weight, urine output, blood pressure, respiratory/lung findings, electrolytes, acid-base state, concurrent enteral/drug fluids and ongoing losses; risk is higher in cats and cardiac/renal patients.
  • Do not mix with phosphate- or carbonate-containing solutions or use as a routine drug diluent/carrier. Verify exact admixture and Y-site compatibility before adding or co-infusing any medicine; use a separate line when compatibility is unknown.
  • Because the solution contains calcium, do not co-infuse blood through the same set unless an exact institutional compatibility protocol explicitly permits it; do not add calcium-chelating or otherwise incompatible medicines.
  • Review potassium supplements, potassium-sparing diuretics and ACE inhibitors for hyperkalaemia risk. Calcium may increase cardiac-glycoside toxicity; use only with deliberate monitoring and verified compatibility.
  • This is a human SEEM presentation used off-label in dogs and cats. Exact-product veterinary sterility/quality dossier, outcome trials and recognised-regulator pharmacovigilance were not located; class evidence and a composition-near authorised veterinary comparator support clinical transfer, not exact-product equivalence.
  • Lactated Ringer's is a replacement crystalloid, not automatically the right long-term maintenance fluid. Prolonged isotonic use may cause sodium derangement and hypokalaemia; reassess fluid composition when the patient is euvolaemic.
  • Use aseptic IV technique and calibrated delivery; inspect container integrity and solution clarity, never use a leaking/cloudy/particulate container, dedicate opened product to one patient and discard unused contents according to the exact pack instruction.
Assessment sources
  1. SEEM exact instruction2026
  2. UZ exact register2022
  3. GE SEEM audit2026
  4. SEEM EU-GB-US checks2026
  5. AAHA fluid guideline2024
  6. AAHA fluid controversies2024
  7. Veterinary Hartmann comparator2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat IV buffered-isotonic crystalloid resuscitation of confirmed hypovolaemia
6.2/10
Situational / acceptable
vetman assessment

Ringer lactate SEEM

solution for infusion, human medicine
Assessed clinical scopeCat · IV buffered-isotonic crystalloid resuscitation of confirmed hypovolaemia · Intravenous
Care settingEmergency/critical-care IV bolus with perfusion reassessment after every 5–10 mL/kg over 15–30 min and particularly strict cumulative-volume surveillance.
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Medium Georgia: No longer listed · № რ-032747, რ-032746 · Verified on 22 Oct 2026 Off-label use

A clinically useful class-level option for feline hypovolaemia, but the exact product has regulatory/evidence limitations and cats require conservative 5–10 mL/kg reassessed boluses with vigilant overload monitoring.

Regulatory and scientific credibility4.5/10

Exact composition and manufacturer instruction are verifiable and a 2022 Uzbek state register corroborates identity and historical legal-market status, but the Georgian certificates expired. The reviewed EU/GB/US searches did not establish current exact-product status and lack the documented same-endpoint positive controls required to prove non-authorisation; veterinary use is off-label and no recognised-regulator veterinary dossier for this presentation was verified.

Clinical efficacy8.0/10

Buffered isotonic crystalloids are a guideline-standard replacement option for the assessed role; benefit is well established at class level, while exact-product veterinary outcome trials are absent and response depends on diagnosis, volume and reassessment.

Safety and tolerability6.0/10

Cats have a narrower practical margin for fluid intolerance and occult cardiac disease; overload/pulmonary oedema may develop quickly, while electrolyte/acid-base shifts and calcium-containing admixture incompatibilities remain and exact-product veterinary safety data are absent.

Clinical practicality6.5/10

The 250 mL presentation and small-bolus guidance are usable in hospital, but feline dosing needs precise low-volume delivery, frequent reassessment and meticulous cumulative accounting; larger packs may create waste or dosing risk.

Full-course cost-effectiveness-

A current Georgian exact-pack price and patient-specific treatment cost were not verified; price is excluded from the denominator.

Important safety and use flags

  • Stop the infusion and urgently reassess restlessness, tachypnoea/increased effort, moist lung sounds, cough, nasal discharge, oedema, rapid weight gain or other suspected fluid overload/pulmonary oedema.
  • Do not use as routine volume loading in a euvolaemic patient or with existing overhydration/pulmonary oedema. Exact SEEM also lists alkalosis, severe hepatic dysfunction, acute renal failure, lactic acidosis and hypertonic dehydration as contraindications.
  • Individualise fluid type, bolus/rate and cumulative volume from perfusion, weight, urine output, blood pressure, respiratory/lung findings, electrolytes, acid-base state, concurrent enteral/drug fluids and ongoing losses; risk is higher in cats and cardiac/renal patients.
  • Do not mix with phosphate- or carbonate-containing solutions or use as a routine drug diluent/carrier. Verify exact admixture and Y-site compatibility before adding or co-infusing any medicine; use a separate line when compatibility is unknown.
  • Because the solution contains calcium, do not co-infuse blood through the same set unless an exact institutional compatibility protocol explicitly permits it; do not add calcium-chelating or otherwise incompatible medicines.
  • Review potassium supplements, potassium-sparing diuretics and ACE inhibitors for hyperkalaemia risk. Calcium may increase cardiac-glycoside toxicity; use only with deliberate monitoring and verified compatibility.
  • This is a human SEEM presentation used off-label in dogs and cats. Exact-product veterinary sterility/quality dossier, outcome trials and recognised-regulator pharmacovigilance were not located; class evidence and a composition-near authorised veterinary comparator support clinical transfer, not exact-product equivalence.
  • Lactated Ringer's is a replacement crystalloid, not automatically the right long-term maintenance fluid. Prolonged isotonic use may cause sodium derangement and hypokalaemia; reassess fluid composition when the patient is euvolaemic.
  • Use aseptic IV technique and calibrated delivery; inspect container integrity and solution clarity, never use a leaking/cloudy/particulate container, dedicate opened product to one patient and discard unused contents according to the exact pack instruction.
Assessment sources
  1. SEEM exact instruction2026
  2. UZ exact register2022
  3. GE SEEM audit2026
  4. SEEM EU-GB-US checks2026
  5. AAHA fluid guideline2024
  6. AAHA fluid controversies2024
  7. Veterinary Hartmann comparator2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat IV replacement of calculated extracellular dehydration deficit and ongoing losses
6.4/10
Situational / acceptable
vetman assessment

Ringer lactate SEEM

solution for infusion, human medicine
Assessed clinical scopeCat · IV replacement of calculated extracellular dehydration deficit and ongoing losses · Intravenous
Care settingHospital IV rehydration: replace the calculated deficit over 12–24 h with strict cumulative-fluid, weight, respiratory, urine-output and chemistry monitoring.
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: No longer listed · № რ-032747, რ-032746 · Verified on 22 Oct 2026 Off-label use

Useful for calculated feline extracellular dehydration under close monitoring, but the narrower feline volume margin and exact-product regulatory/evidence limitations keep it situational rather than a preferred default.

Regulatory and scientific credibility4.5/10

Exact composition and manufacturer instruction are verifiable and a 2022 Uzbek state register corroborates identity and historical legal-market status, but the Georgian certificates expired. The reviewed EU/GB/US searches did not establish current exact-product status and lack the documented same-endpoint positive controls required to prove non-authorisation; veterinary use is off-label and no recognised-regulator veterinary dossier for this presentation was verified.

Clinical efficacy8.0/10

Buffered isotonic crystalloids are a guideline-standard replacement option for the assessed role; benefit is well established at class level, while exact-product veterinary outcome trials are absent and response depends on diagnosis, volume and reassessment.

Safety and tolerability6.0/10

Controlled replacement is effective, but cats are prone to occult cardiac disease and fluid intolerance; overload, pulmonary oedema and electrolyte shifts require closer surveillance, and exact-product feline safety/pharmacovigilance data are absent.

Clinical practicality7.5/10

The 250 mL pack can support precise hospital rehydration, but cats need low-volume calibrated delivery, full accounting of enteral/drug fluids and frequent reassessment; this isotonic fluid is not automatically suitable for prolonged maintenance.

Full-course cost-effectiveness-

A current Georgian exact-pack price and patient-specific treatment cost were not verified; price is excluded from the denominator.

Important safety and use flags

  • Stop the infusion and urgently reassess restlessness, tachypnoea/increased effort, moist lung sounds, cough, nasal discharge, oedema, rapid weight gain or other suspected fluid overload/pulmonary oedema.
  • Do not use as routine volume loading in a euvolaemic patient or with existing overhydration/pulmonary oedema. Exact SEEM also lists alkalosis, severe hepatic dysfunction, acute renal failure, lactic acidosis and hypertonic dehydration as contraindications.
  • Individualise fluid type, bolus/rate and cumulative volume from perfusion, weight, urine output, blood pressure, respiratory/lung findings, electrolytes, acid-base state, concurrent enteral/drug fluids and ongoing losses; risk is higher in cats and cardiac/renal patients.
  • Do not mix with phosphate- or carbonate-containing solutions or use as a routine drug diluent/carrier. Verify exact admixture and Y-site compatibility before adding or co-infusing any medicine; use a separate line when compatibility is unknown.
  • Because the solution contains calcium, do not co-infuse blood through the same set unless an exact institutional compatibility protocol explicitly permits it; do not add calcium-chelating or otherwise incompatible medicines.
  • Review potassium supplements, potassium-sparing diuretics and ACE inhibitors for hyperkalaemia risk. Calcium may increase cardiac-glycoside toxicity; use only with deliberate monitoring and verified compatibility.
  • This is a human SEEM presentation used off-label in dogs and cats. Exact-product veterinary sterility/quality dossier, outcome trials and recognised-regulator pharmacovigilance were not located; class evidence and a composition-near authorised veterinary comparator support clinical transfer, not exact-product equivalence.
  • Lactated Ringer's is a replacement crystalloid, not automatically the right long-term maintenance fluid. Prolonged isotonic use may cause sodium derangement and hypokalaemia; reassess fluid composition when the patient is euvolaemic.
  • Use aseptic IV technique and calibrated delivery; inspect container integrity and solution clarity, never use a leaking/cloudy/particulate container, dedicate opened product to one patient and discard unused contents according to the exact pack instruction.
Assessment sources
  1. SEEM exact instruction2026
  2. UZ exact register2022
  3. GE SEEM audit2026
  4. SEEM EU-GB-US checks2026
  5. AAHA fluid guideline2024
  6. AAHA fluid controversies2024
  7. Veterinary Hartmann comparator2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Sodium chloride6 mg/ml Potassium chloride0.4 mg/ml Calcium chloride0.27 mg/ml Sodium lactate3.2 mg/ml
Formulation Type
Solution
Administration route
Intravenous
Manufacturer
Samarkand England Eco-Medical · Uzbekistan
Registration
Georgia No longer listed
Was registered; not in the current register
Human (Ministry of Health, RAMA)
In the register: რინგერი ლაქტატით
№ რ-032747, რ-032746
Verified on: 22 Oct 2026
 EU Not confirmed
Verified on: 16 Oct 2026
 UK Not confirmed
Verified on: 16 Oct 2026
 US Not confirmed
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified Veterinary use is off-label. Hypovolaemia: dog 15–20 mL/kg IV over 15–30 min; cat 5–10 mL/kg IV over 15–30 min, reassessing perfusion after each bolus. Dehydration: calculate deficit as body weight × dehydration fraction and replace over 12–24 h, adding ongoing losses. Do not transfer the human 2500 mL/day or drop-rate instruction to animals. This isotonic replacement fluid is not automatically an appropriate long-term maintenance fluid.

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 23 Oct 2026

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