Register
Medicines reference
Active substance

Metoclopramide

D2 antagonist prokinetic. Registered in Georgia: 7 human medicines. Forms: solution, tablet.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Metoclopramide
Before use

Safety information

Known Contraindications

  • Critical
    Do not use metoclopramide in patients with gastrointestinal perforation or obstruction. Its prokinetic action can worsen these conditions.
    Sources: Product label
  • Critical
    Do not use metoclopramide in patients with gastrointestinal haemorrhage.
    Sources: Product label
  • Critical
    Known hypersensitivity to the active substance or any excipient is an absolute contraindication on all four reviewed labels. The injectable Emeprid formulation contains metacresol (2 mg/mL) as an excipient.
    Sources: Product label
  • Warning
    Avoid metoclopramide in animals with epilepsy, other seizure disorders, or head trauma because it crosses the blood-brain barrier and may lower the seizure threshold.
    Sources: Product label
  • Warning
    Reduce or otherwise adjust the metoclopramide dose in renal insufficiency because accumulation increases the risk of adverse effects, including extrapyramidal reactions. The product labels do not specify a fixed reduction percentage.
    Sources: Product label
  • Warning
    Reduce the dose in hepatic impairment, as recommended for renal impairment. Metoclopramide is metabolized in the liver.
  • Warning
    Do not use metoclopramide in animals with pheochromocytoma because it may provoke a hypertensive crisis.
    Sources: Product label
  • Warning
    Measure metoclopramide doses especially carefully in cats and small-breed dogs. Severe extrapyramidal or other neurological reactions are very rare but may require medical treatment.
    Sources: Product label
  • Warning
    Safety of metoclopramide in the target species during pregnancy and lactation has not been established. Use only after a veterinarian has assessed the individual benefit and risk.
    Sources: Product label
  • Warning
    After prolonged vomiting, consider fluid and electrolyte replacement. Metoclopramide controls the symptom but does not treat dehydration.
    Sources: Product label
  • Warning (Dog)
    Avoid metoclopramide in dogs with pseudopregnancy because dopamine D2 antagonism increases prolactin and may worsen clinical signs.
    Sources: Product label

Known Drug Interactions

  • Major warning Acepromazine + Metoclopramide
    Concomitant use with phenothiazine neuroleptics such as acepromazine or with butyrophenones increases the risk of extrapyramidal effects: agitation, ataxia, tremor, abnormal movements, vocalization, and aggression. Both agents block D2 receptors, producing an additive effect.
    Recommendation: Avoid the combination where possible. If necessary, use the lowest metoclopramide dose and monitor the animal. Effects are transient and resolve after treatment stops; there is no specific antidote, and a quiet environment is recommended.
  • Minor warning Metoclopramide + Atropine
    In animals with gastritis, avoid giving anticholinergic drugs such as atropine with metoclopramide because they can oppose its effect on gastrointestinal motility.
    Recommendation: Avoid the combination in gastritis because the anticholinergic can oppose metoclopramide. Concomitant diarrhoea alone is not a contraindication to anticholinergic treatment.
    Sources: Product label
Latin name
Metoclopramide
Georgian name
მეტოკლოპრამიდი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
7 of 7 forms
Human medicines in Georgia
Metpami̇d
Human medicines with this substance in the Georgian register of medicines (Ministry of Health), checked on 18 Oct 2026. They are human medicines, not veterinary products; strengths and forms differ.
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration7

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Cerumax 5 mg/ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Cerumax

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-036615 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Cerumax

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-036615 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Registration
Georgia Yes, human
In force until 13 Oct 2027
Human (Ministry of Health, RAMA)
In the register: ცერუმაქსი 5 მგ/მლ, 2 მლ ამპულა
№ რ-036615
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Metoclopramide-Darnitsa 5 mg/ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Metoclopramide-Darnitsa

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-034702 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Metoclopramide-Darnitsa

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-034702 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Darnitsa · Ukraine
Registration
Georgia Yes, human
In force until 18 Mar 2027
Human (Ministry of Health, RAMA)
In the register: მეტოკლოპრამიდი-დარნიცა 5 მგ/მლ, 2 მლ ამპულა
№ რ-034702
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Metoclopramide Borisov 5 mg/ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Metoclopramide Borisov

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035723 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Metoclopramide Borisov

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035723 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Registration
Georgia Yes, human
In force until 30 Jun 2027
Human (Ministry of Health, RAMA)
In the register: მეტოკლოპრამიდი ბორისოვი 5 მგ/მლ, 2 მლ ამპულა
№ რ-035723
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Metoclopramide Ferein 5 mg/ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Metoclopramide Ferein

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035614 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Metoclopramide Ferein

5 mg/ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035614 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Registration
Georgia Yes, human
In force until 22 Jun 2027
Human (Ministry of Health, RAMA)
In the register: მეტოკლოპრამიდი ფერეინი 5 მგ/მლ, 2 მლ ამპულა
№ რ-035614
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Metoclopramide Slavia 10 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by oral route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
5.8/10
Weak evidence support
vetman assessment

Metoclopramide Slavia

10 mg, tablet, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by oral route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · By mouth
Care settingVeterinary-prescribed home or step-down treatment only when the calculated dose can be delivered accurately and the cause and response are actively reviewed
vetman score 5.8/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-036815 · Verified on 16 Oct 2026 Off-label use

The ingredient can be useful for selected canine upper-GI dysmotility, but this 10 mg tablet offers only a 5 mg verified half-dose and is a poor fit for small dogs or fine titration. Use a more accurate formulation when the calculated dose cannot be delivered reliably.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, an identifiable manufacturer, strength and half-tablet split. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy5.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality4.5/10

The tablet can be split only to 5 mg. That can match selected medium or large dogs, but small dogs and dose adjustment commonly require a lower strength or validated compound; repeated q8h home administration and variable oral exposure add burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • This catalogue tablet is 10 mg and its smallest verified split is 5 mg. Do not estimate a feline or small-dog dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated pharmacy compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by oral route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
5.1/10
Weak evidence support
vetman assessment

Metoclopramide Slavia

10 mg, tablet, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by oral route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · By mouth
Care settingVeterinary-prescribed home or step-down treatment only when the calculated dose can be delivered accurately and the cause and response are actively reviewed
vetman score 5.1/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-036815 · Verified on 16 Oct 2026 Off-label use

The ingredient has a plausible feline prokinetic role, but this 10 mg tablet is not a credible dose-delivery form for a typical cat: even its verified half is usually too large. Prefer an accurately measurable lower-strength or validated compounded preparation.

Regulatory and scientific credibility6.5/10

The exact human tablet has sourced current registrations in Georgia and EU/EEA, an identifiable manufacturer, strength and half-tablet split. It has no veterinary authorisation, no checked UK or US exact trade-name registration, and animal use is off-label.

Clinical efficacy5.0/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality1.5/10

The smallest verified half-tablet is 5 mg, above the usual calculated dose for a typical cat. Crushing does not make informal powder division accurate or validated, so most cats require a lower-strength liquid or pharmacy-prepared patient-specific dose.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • This catalogue tablet is 10 mg and its smallest verified split is 5 mg. Do not estimate a feline or small-dog dose from an unmeasured fraction of crushed powder; use an accurately measurable lower strength or validated pharmacy compound.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Slavia Pharm · Romania
Registration
Georgia Yes, human
In force until 10 Nov 2027
Human (Ministry of Health, RAMA)
In the register: მეტოკლოპრამიდი სლავია 10 მგ, აბი
№ რ-036815
Verified on: 16 Oct 2026
EU Yes, human
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Metpamid 10 mg/2 ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Metpamid

10 mg/2 ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046135 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Metpamid

10 mg/2 ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046135 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Sifar · Türkiye
Registration
Georgia Yes, human
In force until 11 Aug 2031
Human (Ministry of Health, RAMA)
In the register: მეტპამიდი 10 მგ/2 მლ, 2 მლ ამპულა
№ რ-046135
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Turktipsan Metoclopramide 10 mg/2 ml, Solution

2 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs
6.4/10
Situational / acceptable
vetman assessment

Turktipsan Metoclopramide

10 mg/2 ml, 2 ml ampoule, human medicine
Assessed clinical scopeDog · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in dogs · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-036410 · Verified on 16 Oct 2026 Off-label use

A situational off-label hospital option when upper-GI dysmotility is part of the problem and obstruction is excluded. It is less reliable as a stand-alone broad antiemetic than newer agents, but the 5 mg/ml ampoule supports accurate IV/IM dosing and monitored short-term use.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy6.5/10

Canine evidence supports upper-GI prokinetic activity and benefit in an experimental postoperative-ileus model; a small prospective parvoviral study also found reduced vomiting. However, a blinded low-dose cisplatin crossover found no anti-nausea or antiemetic effect, and efficacy is less consistent and less broadly acting than newer antiemetics.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats
6.1/10
Situational / acceptable
vetman assessment

Turktipsan Metoclopramide

10 mg/2 ml, 2 ml ampoule, human medicine
Assessed clinical scopeCat · Short-term off-label metoclopramide by IV or IM route as an upper-GI prokinetic and secondary antiemetic for selected non-obstructive nausea, vomiting or delayed gastric emptying in cats · IV,IM
Care settingClinic or hospital use after obstruction and perforation have been excluded; bolus or repeated treatment is selected and monitored by the veterinary team
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-036410 · Verified on 16 Oct 2026 Off-label use

A situational feline prokinetic with direct gastric-emptying evidence, but a comparatively weak stand-alone antiemetic. The 5 mg/ml ampoule is accurately measurable; exclude obstruction, monitor neurologic effects and treat the underlying cause rather than escalating symptom control blindly.

Regulatory and scientific credibility6.0/10

The exact human ampoule has a sourced current Georgian registration and identifiable manufacturer, strength and IV/IM route. Exhaustive checked EU/EEA, UK and US registers contained no exact trade-name match; it has no veterinary authorisation and animal use is off-label.

Clinical efficacy5.5/10

A randomized double-blind crossover in eight healthy cats found faster solid gastric emptying and increased antral motility, supporting a prokinetic role. Feline antiemetic evidence is sparse and low-certainty, dopamine-mediated emesis is less important in cats, and benefit should not be generalized to every vomiting syndrome.

Safety and tolerability6.0/10

Short-term veterinary use is usually manageable, but these exact human products have no dog- or cat-specific safety dossier. Dopamine antagonism can cause agitation, disorientation, sedation, tremor, dystonia, seizures or rare neuroleptic malignant syndrome; renal or hepatic impairment, interacting CNS drugs and cumulative exposure require review.

Clinical practicality7.5/10

The 5 mg/ml, 2 ml ampoule permits accurate weight-based IV or IM dosing in hospital. Repeated q6-8h administration or a CRI still requires staff time, asepsis, venous access when applicable and neurologic monitoring; this exact human ampoule is not recorded for veterinary SC use.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use a prokinetic when gastrointestinal obstruction, perforation or haemorrhage is suspected or confirmed; exclude a mechanical cause before symptom suppression.
  • Avoid in epilepsy or uncontrolled seizure disease and after a serious dystonic or extrapyramidal reaction to metoclopramide; dopamine antagonism can worsen these problems.
  • Avoid or closely review concurrent phenothiazines, antipsychotics and other dopamine antagonists because sedation, dystonia, extrapyramidal signs and neuroleptic malignant syndrome may be additive.
  • Anticholinergic drugs and opioids can oppose the intended motility effect; reassess whether metoclopramide remains useful and monitor sedation and bowel function.
  • Review serotonergic medicines, monoamine-oxidase inhibitors and strong CYP2D6 inhibitors. Monitor agitation, tremor, hyperthermia, autonomic instability or hypertension and stop and reassess if toxicity is suspected.
  • Renal impairment can increase exposure, and severe hepatic disease may reduce clearance. Reconsider dose or interval and monitor neurologic effects in organ-impaired patients.
  • Stop and reassess for new agitation, disorientation, abnormal movements, tremor, rigidity, hyperthermia or autonomic instability. Keep treatment as short as clinically justified because neurologic risk rises with cumulative exposure.
  • Give IV boluses slowly and follow aseptic single-use ampoule practice. This exact human presentation is recorded for IV/IM use; do not infer that general veterinary SC guidance authorises the SC route for this ampoule.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Turktipsan · Türkiye
Registration
Georgia Yes, human
In force until 14 Sep 2027
Human (Ministry of Health, RAMA)
In the register: ტურქტიპსან მეტოკლოპრამიდი 10 მგ/2 მლ, 2 მლ ამპულა
№ რ-036410
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.