Nothing found. Try the Latin name or the product name.
Search
Nothing found. Try the Latin name or the product name.
Propylene glycol
Solvent and carrier (excipient). Used in veterinary practice (cat); overdose thresholds from published sources, not treatment doses.
Overdose
Used in veterinary practice at veterinary doses; human tablets and gels are much stronger and cannot be dosed accurately for an animal. The table shows where harm has been described after a single ingestion, mg per kg of body weight: overdose thresholds, not treatment doses.
| Species | Signs begin | Severe | Deaths reported | Source |
|---|---|---|---|---|
| Cat | not established | not established | not established |
Christopher et al. 1989 · Bauer et al. 1992 +1
High confidence
Feeding studies in cats and a US regulation (Christopher et al. 1989; Bauer et al. 1992; 21 CFR 589.1001). Scientific article A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied. Journal of the American Veterinary Medical Association, J Am Vet Med Assoc 1989;194(8):1045-1056, 1989 1.6 g/kg/day (12% of diet): Heinz bodies 28%; 8 g/kg/day (41%): anaemia Scientific article A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied. American Journal of Veterinary Research, Am J Vet Res 1992;53(1):69-72, 1992 dose-related Heinz bodies and shorter RBC survival from 6% of diet Guideline or consensus statement Recommendations agreed by a panel of veterinary specialists after reviewing the evidence. They guide practice and do not authorise a product. Code of Federal Regulations, Title 21, 21 CFR 589.1001 (61 FR 19544, 1996), 1996 propylene glycol not shown to be safe in or on cat food |
Cat
Signs: Heinz bodies, shorter red-cell survival; at high intake anaemia.
Propylene glycol taken by mouth every day (semi-moist foods, oral solutions) raises Heinz bodies and shortens red-cell life in cats in a dose-dependent way, already at 6% of the diet; at 41% of the diet it caused anaemia. The US does not allow it in cat food. It is also a solvent in some medicines: this record concerns repeated oral intake.
Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.
For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.
Trademarks belong to their owners; vetman is not affiliated with the manufacturers and receives no payment from them.
The database is protected under Chapter VII of the Law of Georgia on Copyright and Related Rights; automated or bulk copying is prohibited.
This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 22 Oct 2026