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Toxic substances: dog and cat
Plants

Sago palm (Cycas revoluta)

cycad, Cycas

A professional reference for veterinary specialists. It does not replace clinical judgement.

If an animal has ingested this, contact a veterinarian immediately.

Species and toxic dose

SpeciesRiskToxic dose
Dog Especially sensitive 1-2 seeds can be fatal.
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Cat Toxic Not established in the open sources

Toxic principle

Cycasin (converted by gut bacteria to methylazoxymethanol), the amino acid BMAA and an unidentified high-molecular-weight compound; seeds hold the most.

Onset

Digestive signs within about 4 hours (4-24 hours); liver injury at 1-3 days.

Clinical signs

Vomiting, haematemesis, melaena, bloody diarrhoea; icterus, petechiae and bruising, coagulopathy; hypoglycaemia, tremors, ataxia, seizures. Raised ALT and ALP, hyperbilirubinaemia, hypoalbuminaemia.

Organs affected

Liver, digestive tract, central nervous system, coagulation.

Treatment principle (for veterinarians)

Decontamination with activated charcoal, supportive care, liver support (N-acetylcysteine, vitamin K1), anticonvulsants as needed. Survival 36-50% in two retrospective studies; a low albumin or platelet count predicts death.

A summary of the principles in the sources, not a protocol: doses and the plan are the treating veterinarian's decision.

Sources

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.