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Toxic substances: dog and cat
Metals and objects

Lead

lead paint, shot, fishing weights

A professional reference for veterinary specialists. It does not replace clinical judgement.

If an animal has ingested this, contact a veterinarian immediately.

Species and toxic dose

SpeciesRiskToxic dose
Dog Toxic Lowest reported single lethal dose 300 mg/kg; chronic effects from about 1-3.3 mg/kg a day.
Scientific article
A study or review published in a scientific journal. Its findings apply to the animals and conditions it studied.
Cat Toxic Not established in the open sources

Toxic principle

Lead binds protein thiol groups, takes the place of calcium and inhibits haem synthesis; it damages neurons. Stomach acid increases absorption, which is 5-15% in adults and up to 50% in the young.

Onset

Acute and chronic forms; the sources give no timeline.

Clinical signs

Digestive: vomiting, diarrhoea, colic, loss of appetite. Nervous: behaviour change, ataxia, tremors, intermittent seizures. Weight loss. Anaemia with basophilic stippling and nucleated red cells; blood lead of 40-60 µg/dl or more supports the diagnosis.

Organs affected

Digestive tract, central nervous system, blood, kidneys, bone.

Treatment principle (for veterinarians)

Remove lead from the gut before chelation (emesis, lavage, cathartics, enema, endoscopy or surgery); activated charcoal does not bind lead. Benzodiazepines for seizures. Chelation with calcium EDTA or succimer; penicillamine and dimercaprol are alternatives.

A summary of the principles in the sources, not a protocol: doses and the plan are the treating veterinarian's decision.

Sources

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.