1 form: solution. In force in Georgia: 1 of 1 (veterinary register).
Forms and doses1 of 1 in force in Georgia
The dose from the product's label, by species and weight. Check the label of the pack you use.
Form
Species
Weight
Dose
Frequency
Georgia
Solution · Cat Any weight
Cat
Any weight
0.08 ml/kg
Sedation and analgesia for non-invasive, mildly to moderately painful procedures and examinations, and premedication before general anaesthesia: the same dose for both, 40 µg/kg (0.08 ml/kg), into a muscle only. Not for repeat injection. Label table: 1-2 kg 0.1 ml; 2-3 kg 0.2 ml; 3-4 kg 0.3 ml; 4-6 kg 0.4 ml; 6-7 kg 0.5 ml; 7-8 kg 0.6 ml; 8-10 kg 0.7 ml. After premedication, induction can follow in 10 minutes (ketamine 5 mg/kg IM, or propofol IV to effect).
Dexmedetomidine hydrochloride 0.5 mg/ml, solution for injection for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
DogFull canine label: restraint, sedation and analgesia for non-invasive mildly to moderately painful procedures; deep sedation with butorphanol; premedication; and CRI during inhalation anaesthesia
8.3/10
Very good
CatFull feline label: restraint, sedation and analgesia for non-invasive mildly to moderately painful procedures; premedication; and CRI during inhalation anaesthesia
Sedation and analgesia for non-invasive, mildly to moderately painful procedures and examinations, and premedication before general anaesthesia: the same dose for both, 40 µg/kg (0.08 ml/kg), into a muscle only. Not for repeat injection. Label table: 1-2 kg 0.1 ml; 2-3 kg 0.2 ml; 3-4 kg 0.3 ml; 4-6 kg 0.4 ml; 6-7 kg 0.5 ml; 7-8 kg 0.6 ml; 8-10 kg 0.7 ml. After premedication, induction can follow in 10 minutes (ketamine 5 mg/kg IM, or propofol IV to effect).
Cat
Any weight
Intramuscular
once
VMD SPC 2026
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Dexdomitor 0.5 mg/ml solution for injection for dogs and cats - Summary of Product Characteristics
Deep Sedation and Analgesia with Butorphanol · Intramuscular
Premedication · Intravenous / Intramuscular
2–3 kg
0.12 ml
0.15 ml
0.12 ml
0.04–0.12 ml
3–4 kg
0.17 ml
0.2 ml
0.16 ml
0.05–0.17 ml
4–5 kg
0.2 ml
0.3 ml
0.2 ml
0.07–0.2 ml
5–10 kg
0.29 ml
0.4 ml
0.25 ml
0.1–0.29 ml
10–13 kg
0.38 ml
0.5 ml
0.3 ml
0.13–0.38 ml
13–15 kg
0.44 ml
0.6 ml
0.35 ml
0.15–0.44 ml
15–20 kg
0.51 ml
0.7 ml
0.4 ml
0.17–0.51 ml
20–25 kg
0.6 ml
0.8 ml
0.5 ml
0.2–0.6 ml
25–30 kg
0.69 ml
0.9 ml
0.55 ml
0.23–0.69 ml
30–33 kg
0.75 ml
1 ml
0.6 ml
0.25–0.75 ml
33–37 kg
0.81 ml
1.1 ml
0.65 ml
0.27–0.81 ml
37–45 kg
0.9 ml
1.2 ml
0.7 ml
0.3–0.9 ml
45–50 kg
0.99 ml
1.3 ml
0.8 ml
0.33–0.99 ml
50–55 kg
1.06 ml
1.4 ml
0.85 ml
0.35–1.06 ml
55–60 kg
1.13 ml
1.5 ml
0.9 ml
0.38–1.13 ml
60–65 kg
1.19 ml
1.6 ml
0.95 ml
0.4–1.19 ml
65–70 kg
1.26 ml
1.7 ml
1 ml
0.42–1.26 ml
70–80 kg
1.35 ml
1.8 ml
1.1 ml
0.45–1.35 ml
over 80 kg
1.42 ml
1.9 ml
1.2 ml
0.47–1.42 ml
Sedation · Intravenous (once; not for repeat injection): Sedation and analgesia for non-invasive, mildly to moderately painful procedures and examinations: up to 375 µg/m² into a vein, given as the label volume for the weight band. Not for repeat injection.
Sedation · Intramuscular (once; not for repeat injection): Sedation and analgesia for non-invasive, mildly to moderately painful procedures and examinations: up to 500 µg/m² into a muscle, given as the label volume for the weight band. Not for repeat injection.
Deep Sedation and Analgesia with Butorphanol · Intramuscular (once, with butorphanol 0.1 mg/kg): Deep sedation and analgesia for medical and minor surgical procedures, with butorphanol 0.1 mg/kg (the two may share a syringe): 300 µg/m² into a muscle. Effect within 15 minutes, peak at 30; sedation lasts at least 120 minutes, analgesia at least 90.
Premedication · Intravenous / Intramuscular (once, 20 minutes before induction): Premedication before induction and maintenance of general anaesthesia: 125-375 µg/m² into a vein or a muscle, adjusted to the type and length of surgery and to temperament. Give induction and maintenance drugs to effect (in the label study propofol needs fell by 30%, thiopental by 60%).
Source:
VMD SPC 2026
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Dexdomitor 0.5 mg/ml solution for injection for dogs and cats - Summary of Product Characteristics
Do not use dexmedetomidine in dogs or cats with cardiovascular disease.
Sources: FDA
Critical
Do not use dexmedetomidine in animals with clinically important bradyarrhythmia. It can cause profound sinus bradycardia, first- or second-degree atrioventricular block, and sinus arrest.
Critical
Do not use DEXDOMITOR in dogs or cats with... respiratory disorders
Sources: FDA
Critical
Do not use dexmedetomidine in dogs or cats with hepatic disease because reduced hepatic blood flow or metabolism may prolong and intensify its effects.
Sources: FDA
Critical
Do not use DEXDOMITOR in dogs or cats with... liver or kidney diseases
Sources: FDA
Critical
Known hypersensitivity to dexmedetomidine or any excipient, including methyl- or propyl parahydroxybenzoate, is a contraindication.
Warning
Dexmedetomidine is not recommended during pregnancy because safety in the target species has not been established.
Warning
Dexmedetomidine is not recommended during lactation because safety in the target species has not been established.
Sources: Dexdomitor SPC
Caution
Do not use this anaesthetic product in animals with severe systemic disease, shock, profound debilitation, moribund status, or severe stress from extreme temperature or fatigue. It is not intended for repeated injections.
Sources: FDA
Caution
Dexmedetomidine has not been studied in puppies younger than 16 weeks or kittens younger than 12 weeks. Use cautiously in elderly animals.
Centrally acting drugs, including tranquillisers, sedatives, and hypnotics, can increase buprenorphine-induced drowsiness. Combined use with sedatives can also increase depression of heart rate and respiration.
Recommendation: Reduce the sedative dose during premedication; monitor heart rate and respiration.
Methadone can potentiate analgesics, central nervous system depressants, and drugs that cause respiratory depression. Lower doses may be needed when these medicines are combined.
Recommendation: Reduce doses when used in combination; monitor heart rate and respiration.
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