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Megestrol acetate · AVZ S-P Ltd

1 form: scored tablet. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
5 mg tablets, Scored tablet · Cat Any weight Cat Any weight Estrus Prevention · By mouth: 1 tabletEstrus Interruption · By mouth: 1 tabletSuppression of Sexual Behaviour · By mouth: 1 tablet - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog up to 5 kg Dog up to 5 kg Estrus Prevention · By mouth: 1/2 tabletEstrus Interruption · By mouth: 2 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog Any weight Dog Any weight Estrus Prevention · By mouth: -Estrus Interruption · By mouth: -Suppression of Sexual Behaviour · By mouth: 1 tablet per 5 kg - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog 5–10 kg Dog 5–10 kg Estrus Prevention · By mouth: 1 tabletEstrus Interruption · By mouth: 4 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog 10–15 kg Dog 10–15 kg Estrus Prevention · By mouth: 1 1/2 tabletsEstrus Interruption · By mouth: 6 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog 15–20 kg Dog 15–20 kg Estrus Prevention · By mouth: 2 tabletsEstrus Interruption · By mouth: 8 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog 20–30 kg Dog 20–30 kg Estrus Prevention · By mouth: 3 tabletsEstrus Interruption · By mouth: 12 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
5 mg tablets, Scored tablet · Dog 30–40 kg Dog 30–40 kg Estrus Prevention · By mouth: 4 tabletsEstrus Interruption · By mouth: 16 tabletsSuppression of Sexual Behaviour · By mouth: - - Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

EX-5T 5 mg tablets, Scored tablet

N10 for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: oestrus postponement and interruption in bitches by a weight table up to 40 kg, and a short course for male dogs, with megestrol acetate 5 mg scored tablets
4.9/10
Weak evidence support
vetman assessment

EX-5T

5 mg tablets, N10 for dogs and cats
Assessed clinical scopeDog · Full dog label: oestrus postponement and interruption in bitches by a weight table up to 40 kg, and a short course for male dogs, with megestrol acetate 5 mg scored tablets · By mouth
Care settingVeterinary prescription for a healthy, sexually mature dog after excluding pregnancy and reproductive and mammary disease, with exact cycle timing and follow-up checks
vetman score 4.9/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 002538 · Verified on 21 Oct 2026

A weak option: effective short-term oestrus control with uterine, mammary and endocrine risks. Prefer surgical neutering, or a deslorelin implant in male dogs, for long-term control.

Regulatory and scientific credibility4.5/10

The exact product is registered in Georgia (002538), but that registration runs only to 12 November 2026; it has a current Russian manufacturer instruction and no EU, UK or US authorisation was documented in the reviewed evidence.

Clinical efficacy6.5/10

Megestrol acetate is an established way to postpone or interrupt oestrus in bitches, but timing is critical, no study of this product exists and the weight table stops at 40 kg.

Safety and tolerability3.5/10

Progestogens can cause cystic endometrial hyperplasia and pyometra, mammary nodules, insulin resistance and acromegaly in dogs; short labelled courses lower these risks but do not remove them.

Clinical practicality5.5/10

Doses follow a clear weight table, but interruption needs up to 16 tablets a day for a 30-40 kg bitch, and postponement must start 7-15 days before the expected oestrus.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not use in pregnancy or lactation, before sexual maturity, at the first oestrus, or with reproductive disease, mammary tumours or diabetes.
  • Watch for vaginal discharge, lethargy, thirst or abdominal swelling after a course; pyometra can develop weeks later.
  • Give no more than two interruption courses a year, and no more than 32 days of postponement dosing.
  • The label gives no dose above 40 kg; do not extrapolate.
  • The Georgian registration expires on 12 November 2026; check its renewal before stocking.
Assessment sources
  1. AVZ EX-5T2026
  2. Georgia NFA register 20262026
  3. Canine estrus control2024
  4. Estrous-cycle manipulation2025
  5. EMA Suprelorin EPAR2024
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: oestrus prevention and interruption in queens and suppression of sexual activity in tomcats with megestrol acetate 5 mg scored tablets
4.8/10
Weak evidence support
vetman assessment

EX-5T

5 mg tablets, N10 for dogs and cats
Assessed clinical scopeCat · Full cat label: oestrus prevention and interruption in queens and suppression of sexual activity in tomcats with megestrol acetate 5 mg scored tablets · By mouth
Care settingVeterinary prescription for a healthy, sexually mature cat after excluding pregnancy, reproductive and mammary disease and diabetes, with follow-up checks
vetman score 4.8/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 002538 · Verified on 21 Oct 2026

A weak option: a conveniently sized megestrol tablet whose long-term use in cats risks diabetes, mammary tumours and pyometra. Use short supervised courses only and prefer surgical neutering for lasting control.

Regulatory and scientific credibility4.5/10

The exact product is registered in Georgia (002538), but that registration runs only to 12 November 2026; it has a current Russian manufacturer instruction and no EU, UK or US authorisation was documented in the reviewed evidence.

Clinical efficacy6.0/10

Megestrol acetate is an established way to prevent or interrupt oestrus in queens and to damp male sexual behaviour, but no study of this product exists and control lasts only while dosing continues.

Safety and tolerability3.0/10

Cats are especially sensitive to progestogens: diabetes mellitus, adrenal suppression, mammary hyperplasia and tumours, pyometra and weight gain are documented, and the risk grows with dose and duration up to the labelled 18 months.

Clinical practicality6.0/10

The 5 mg scored tablet fits cat doses of half or one tablet well, and the weekly or two-weekly schedules are simple.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not use in pregnancy or lactation, before sexual maturity, at the first oestrus, or with reproductive disease, mammary tumours or diabetes.
  • Check glucose and palpate the mammary glands before and during long courses; stop at the first sign of increased thirst, urination or mammary swelling.
  • Interrupt oestrus no more than twice a year and do not exceed 18 months of continuous prevention.
  • Male cats on long or repeated courses can gain weight, change behaviour and develop mammary enlargement.
  • The Georgian registration expires on 12 November 2026; check its renewal before stocking.
Assessment sources
  1. AVZ EX-5T2026
  2. Georgia NFA register 20262026
  3. Feline estrus control2024
  4. Megestrol behaviour warning2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Megestrol acetate5 mg/tablet
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
AVZ S-P Ltd · Russia
Manufacturer (register)
AVZ S-P Ltd, Russia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 487, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
In force until 12 Nov 2026
Veterinary (National Food Agency)
In the register: ეკს-5ტ
№ 002538
Verified on: 21 Oct 2026
Controlled in Georgia
Unknown
Cat
WeightEstrus Prevention · By mouthEstrus Interruption · By mouthSuppression of Sexual Behaviour · By mouth
Any weight 1 tablet 1 tablet 1 tablet
  • Estrus Prevention · By mouth (0.5 tablet weekly, or use the separate 1-tablet every-2-weeks schedule; maximum 18 months): Female cat only. Begin between cycles and outside breeding season. Do not use during pregnancy, lactation, sexual immaturity, first estrus, reproductive disease, mammary tumor or diabetes.
  • Estrus Interruption · By mouth (once daily for 5-7 days, started no later than day 3 of estrus): Female cat only. Do not interrupt estrus more than twice yearly.
  • Suppression of Sexual Behaviour · By mouth (once daily for 5-7 days, then once weekly): Male cat only. Long or repeated use may alter behaviour, enlarge mammary glands and increase appetite and weight.
Source:
AVZ EX-5T
Manufacturer material
Information published by the maker or a seller, such as a datasheet or product page. A medicines regulator has not necessarily reviewed it.
EX-5T tablets - current official instruction
Current official manufacturer instruction, 2026
Dog
WeightEstrus Prevention · By mouthEstrus Interruption · By mouthSuppression of Sexual Behaviour · By mouth
up to 5 kg 1/2 tablet 2 tablets -
Any weight - - 1 tablet per 5 kg
5–10 kg 1 tablet 4 tablets -
10–15 kg 1 1/2 tablets 6 tablets -
15–20 kg 2 tablets 8 tablets -
20–30 kg 3 tablets 12 tablets -
30–40 kg 4 tablets 16 tablets -
  • Estrus Prevention · By mouth (once daily, beginning 7-15 days before estrus; maximum 32 days): Bitch only. Observe all hormonal contraindications and the exact weight table.
  • Estrus Interruption · By mouth (full dose daily for 3 days, then half dose daily for 7 days): Bitch only. Start no later than day 3 of estrus and do not use more than two courses yearly.
  • Suppression of Sexual Behaviour · By mouth (once daily for 7 days): Male dog only. Do not use with the product hormonal contraindications.
Source:
AVZ EX-5T
Manufacturer material
Information published by the maker or a seller, such as a datasheet or product page. A medicines regulator has not necessarily reviewed it.
EX-5T tablets - current official instruction
Current official manufacturer instruction, 2026

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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