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Active substance

Chlortetracycline

Favourites

Tetracycline. Registered in Georgia: 2 veterinary products. Forms: aerosol / spray.

Dose and use

Doses

We have no dose with a cited source for this substance yet.

Before use

Safety information

Known Contraindications

  • Critical
    Do not use if hypersensitive to tetracyclines or excipients.
    Source: EMA Sources: Spanish SPC · EU UPD
  • Caution
    Spray: protect the eyes when treating near the head, and stop the animal licking the treated area.
    Source: EMA Sources: Spanish SPC · EU UPD
Latin name
Chlortetracycline
Georgian name
ქლორტეტრაციკლინი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
2 of 2 forms
Products
Apoderm, Super’s Spray
Controlled in Georgia
Unknown
All forms and registration2

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Apoderm 21.5 mg/ml, Aerosol / spray

chlortetracycline hydrochloride, cutaneous spray suspension
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
6.9/10
Situational / acceptable
vetman assessment

Apoderm

21.5 mg/ml, chlortetracycline hydrochloride, cutaneous spray suspension
Assessed clinical scopeDog · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 6.9/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, veterinary · № 000591 · Verified on 22 Oct 2026

A transparent, authorised topical antibiotic with a clear technique for a selected susceptible superficial wound. Its repeated daily-until-healed regimen is workable but burdensome and requires active review because independent exact-product outcomes are absent and antiseptics are usually preferred first.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.5/10

The exact label supports susceptible superficial contaminated wounds and topical antibacterial therapy is clinically plausible, but no independent outcome trial for this formulation was found. Current canine guidance prioritises antiseptics and does not establish chlortetracycline as a preferred pyoderma agent; the score does not extend to deep wounds or routine empirical pyoderma.

Safety and tolerability7.5/10

Very rare local skin reactions are labelled across target species and systemic exposure is expected to be limited. Ocular exposure, licking, sensitisation, aerosol inhalation, prolonged antibiotic use and flammable propellant remain meaningful but manageable under correct use.

Clinical practicality6.5/10

The ready-to-use 2–3-second application is simple, but one or two treatments every day until complete healing creates a meaningful at-home restraint/adherence burden and an open-ended antibiotic course that requires active review.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 15–20 cm away and spray for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Document progress and reassess the need for continued antibiotic exposure rather than treating “until healed” as an automatic unlimited course.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • Laboratory mouse, rat and rabbit studies found no maternal, fetal or teratogenic effects, but this is not a controlled exact-product dog/cat reproductive dataset. Use in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Apoderm exact2025
  2. NFA CTC sprays exact2026
  3. ISCAID canine pyoderma guideline2025
  4. AAFP/AAHA stewardship2022
  5. MSD small-animal wounds2026
  6. WSAVA acute wounds2013
  7. VMD CTC spray control2026
  8. FDA CTC index2026
  9. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
6.5/10
Situational / acceptable
vetman assessment

Apoderm

21.5 mg/ml, chlortetracycline hydrochloride, cutaneous spray suspension
Assessed clinical scopeCat · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 000591 · Verified on 22 Oct 2026

An authorised but situational feline option for a selected susceptible superficial wound. Direct cat outcomes are absent and the repeated daily aerosol regimen creates important restraint, eye-exposure and grooming-prevention burdens.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.0/10

The exact all-species label supports selected superficial feline wounds, but no direct feline outcome study was identified. General wound-care and stewardship evidence is indirect and cannot establish comparative benefit, deep-wound efficacy or routine empirical use.

Safety and tolerability7.0/10

Very rare local reactions are labelled, but direct feline safety outcomes are absent. Grooming/ingestion, eye transfer, repeated aerosol exposure and restraint burden reduce the margin; drying and prevention of licking are essential.

Clinical practicality5.5/10

Twice-possible daily aerosol restraint until complete healing, followed by drying and grooming prevention, is a substantial feline treatment burden. The technique is simple, but repeated safe execution and stewardship review are not.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 15–20 cm away and spray for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Document progress and reassess the need for continued antibiotic exposure rather than treating “until healed” as an automatic unlimited course.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • Laboratory mouse, rat and rabbit studies found no maternal, fetal or teratogenic effects, but this is not a controlled exact-product dog/cat reproductive dataset. Use in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Apoderm exact2025
  2. NFA CTC sprays exact2026
  3. AAFP/AAHA stewardship2022
  4. MSD small-animal wounds2026
  5. WSAVA acute wounds2013
  6. VMD CTC spray control2026
  7. FDA CTC index2026
  8. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Chlortetracycline21.5 mg/ml
Formulation Type
Aerosol / spray
Administration route
On the skin
Manufacturer
Laboratorios Ovejero S.A.U. · Spain
Manufacturer (register)
Laboratorios Ovejero S.A, Spain
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1059, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
In force until 20 Jun 2029
Veterinary (National Food Agency)
In the register: აპოდერმი
№ 000591
Verified on: 22 Oct 2026
 EU Yes, veterinary
№ 270 ESP
Verified on: 22 Oct 2026
 UK No
Verified on: 22 Oct 2026
 US No
Verified on: 22 Oct 2026
Controlled in Georgia
Unknown
Information not fully verified Dogs/cats, susceptible contaminated superficial traumatic or surgical wounds: clean and remove necrotic tissue, shake, spray from 15–20 cm for 2–3 seconds until evenly coloured, 1–2 times daily until complete healing. Reassess response and ongoing antibiotic need.

Super’s Spray, Aerosol / spray

chlortetracycline 103.51 mg/g, cutaneous spray suspension
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
7.1/10
Good
vetman assessment

Super’s Spray

chlortetracycline 103.51 mg/g, cutaneous spray suspension
Assessed clinical scopeDog · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 7.1/10 Good
Evidence confidence: Medium Georgia: Yes, veterinary · Verified on 22 Oct 2026

A transparent, authorised topical antibiotic with a simple brief application for a narrowly defined susceptible superficial wound. It is clinically usable after proper wound care, but independent exact-product outcomes are absent and current canine stewardship favours antiseptics before topical antibiotics.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.5/10

The exact label supports susceptible superficial contaminated wounds and topical antibacterial therapy is clinically plausible, but no independent outcome trial for this formulation was found. Current canine guidance prioritises antiseptics and does not establish chlortetracycline as a preferred pyoderma agent; the score does not extend to deep wounds or routine empirical pyoderma.

Safety and tolerability7.5/10

Cutaneous absorption is labelled negligible and allergic reactions are rare across target species. Correct superficial use is generally favourable, but ocular exposure, licking, local irritation/allergy, aerosol inhalation, prolonged-use superinfection and flammable propellant require controls.

Clinical practicality7.5/10

A ready-to-use brief spray after wound preparation is simple in clinic or for an instructed home caregiver. Repetition by lesion evolution is flexible, but the absent fixed interval and stop rule require documented reassessment rather than indefinite use.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 20 cm away and spray for a few seconds until evenly coloured. Repeat only according to lesion evolution/severity; no fixed interval, maximum duration or stop rule is stated, so reassess rather than continue indefinitely.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • The exact label describes no pregnancy/lactation contraindication, but no controlled exact-product canine/feline reproductive outcome study was identified. Use repeated or extensive treatment in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Super’s exact2024
  2. NFA CTC sprays exact2026
  3. ISCAID canine pyoderma guideline2025
  4. AAFP/AAHA stewardship2022
  5. MSD small-animal wounds2026
  6. WSAVA acute wounds2013
  7. VMD CTC spray control2026
  8. FDA CTC index2026
  9. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria
6.6/10
Situational / acceptable
vetman assessment

Super’s Spray

chlortetracycline 103.51 mg/g, cutaneous spray suspension
Assessed clinical scopeCat · Label-concordant adjunctive topical treatment of properly cleaned superficial traumatic or surgical wounds contaminated with chlortetracycline-susceptible bacteria · On the skin
Care settingVeterinary-assessed wound care with supervised clinic or instructed home application and active reassessment
vetman score 6.6/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · Verified on 22 Oct 2026

An authorised feline option for a selected susceptible superficial wound, but supported mainly by the exact label rather than direct cat outcomes. Aerosol restraint, eye protection and grooming prevention make it situational.

Regulatory and scientific credibility8.0/10

The exact formulation, full current Spanish product information, valid EU/EEA national authorisation and exact Georgian registration are verifiable. The dossier is transparent, but no independent exact-product dog/cat outcome trial was identified.

Clinical efficacy5.0/10

The exact all-species label supports selected superficial feline wounds, but no direct feline outcome study was identified. General wound-care and stewardship evidence is indirect and cannot establish comparative benefit, deep-wound efficacy or routine empirical use.

Safety and tolerability7.0/10

Negligible cutaneous absorption and rare labelled allergy support a generally favourable profile, but direct feline outcomes are absent and grooming/ingestion, eye transfer, restraint and aerosol exposure add uncertainty. Prevent licking until dry and use only a small accessible superficial field.

Clinical practicality6.5/10

The spray is quick, but many cats resist aerosol sound/restraint and readily groom treated skin. A safe small field is feasible only when eyes can be protected and licking prevented; the unscheduled repeat instruction requires close follow-up.

Full-course cost-effectiveness-

Current Georgian pack price and comparable full-course costs were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Hard stop: do not use with chlortetracycline, another tetracycline or excipient hypersensitivity. Stop and reassess urticaria, facial swelling, dyspnoea, collapse or an important local skin reaction.
  • Scope boundary: superficial traumatic or surgical wounds with a susceptible bacterial component only. Not for eyes, mucosa, ear canals, mouth, deep or puncture wounds, bites, abscesses, body cavities, widespread pyoderma or systemic infection.
  • Exact technique: remove dirt and necrotic tissue, shake, hold 20 cm away and spray for a few seconds until evenly coloured. Repeat only according to lesion evolution/severity; no fixed interval, maximum duration or stop rule is stated, so reassess rather than continue indefinitely.
  • Wound care first: stabilise and provide analgesia as needed, clip, lavage, debride, remove foreign material, drain and plan closure/dressings. This spray is an adjunct and cannot rescue inadequate source control or replace systemic treatment when infection is deep or systemic.
  • Antimicrobial stewardship: use only for a proven or strongly suspected susceptible bacterial component. Obtain culture/susceptibility for infected, recurrent, complicated or non-responsive wounds when indicated. Current canine guidance generally prioritises antiseptics before topical antibiotics.
  • Protect eyes and mucosa and avoid aerosol inhalation. Apply in open air or a well-ventilated area; prevent the patient and other animals from licking or grooming the treated site until fully dry. Flush accidental eye/mucosal exposure promptly with abundant clean water.
  • Reassess promptly for worsening pain, heat, swelling, purulent discharge, necrosis, fever/systemic illness, delayed healing or no clear response. Prolonged use can select resistant/non-susceptible organisms, including fungi, and cross-resistance may reduce other tetracyclines’ usefulness.
  • Interaction/compatibility data with other local treatments are absent or limited. Do not mix or layer another topical antibiotic, antiseptic, wound gel or dressing product over the same site unless compatibility and the treatment sequence are verified.
  • The exact label describes no pregnancy/lactation contraindication, but no controlled exact-product canine/feline reproductive outcome study was identified. Use repeated or extensive treatment in breeding, pregnant or lactating patients only after explicit benefit–risk assessment.
  • Handler/fire safety: chlortetracycline can sensitise skin and cause contact dermatitis; the aerosol can irritate eyes and airways. Wear impermeable gloves for repeated handling, wash hands, avoid eating/drinking/smoking, and keep the pressurised extremely flammable can below 45 °C and away from sunlight, heat, sparks and flames. Do not puncture or burn it.
Assessment sources
  1. AEMPS Super’s exact2024
  2. NFA CTC sprays exact2026
  3. AAFP/AAHA stewardship2022
  4. MSD small-animal wounds2026
  5. WSAVA acute wounds2013
  6. VMD CTC spray control2026
  7. FDA CTC index2026
  8. FDA topical control2001
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Chlortetracycline103.51 mg/g
Formulation Type
Aerosol / spray
Administration route
On the skin
Manufacturer
Super’s Diana S.L. · Spain
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სუპერ’ს სპრეი ქლორტეტრაციკლინი
Verified on: 22 Oct 2026
 EU Yes, veterinary
№ 517 ESP
Verified on: 22 Oct 2026
 UK No
Verified on: 22 Oct 2026
 US No
Verified on: 22 Oct 2026
Controlled in Georgia
Unknown
Information not fully verified Dogs/cats, susceptible contaminated superficial traumatic or surgical wounds: clean and remove necrotic tissue, shake, spray from 20 cm for a few seconds until evenly coloured; repeat by evolution/severity. No fixed interval or maximum duration is stated—reassess rather than continue indefinitely.

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 23 Oct 2026

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