Register
Medicines reference
Active substance

Famotidine

H2 receptor antagonist. Registered in Georgia: 3 human medicines. Forms: powder, tablet.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Famotidine
Before use

Safety information

Known Contraindications

  • Warning
    Do not use acid-suppressant drugs as antiemetics. Vomiting can be the primary sign of gastritis in dogs and cats, but acid suppression does not treat nausea or vomiting itself.
    Sources: ACVIM
  • Warning
    H2-receptor antagonists are eliminated through a combination of renal excretion and hepatic metabolism. Accumulation is expected when both organs are impaired; no specific dose-reduction schedule is provided.
    Sources: ACVIM
  • Warning
    In hepatic impairment, account for reduced elimination through one of the two principal clearance pathways; see the corresponding renal-impairment warning.
Latin name
Famotidine
Georgian name
ფამოტიდინი
Authorisation status
Human medicine, cascade use
No veterinary authorisation was found in any register checked. Veterinary use is off-label, under the prescribing cascade.
Registered in Georgia
3 of 3 forms
Products
Human medicines in Georgia
Proksifam, Quamatel
Human medicines with this substance in the Georgian register of medicines (Ministry of Health), checked on 18 Oct 2026. They are human medicines, not veterinary products; strengths and forms differ.
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration3

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Kvamatel 20 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis
6.3/10
Situational / acceptable
vetman assessment

Kvamatel

20 mg, tablet, human medicine
Assessed clinical scopeDog · Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis · By mouth
Care settingVeterinary-directed short course in hospital or at home, normally twice daily, with diagnosis, response, renal function, duration and a more effective proton-pump inhibitor option reassessed.
vetman score 6.3/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043672 · Verified on 15 Oct 2026 Off-label use

A credible short-term H2 blocker in a transparent human product, but clearly inferior to a PPI for sustained acid suppression. The whole 20 mg unit is practical only for selected large dogs; smaller patients need a dose-appropriate formulation.

Regulatory and scientific credibility6.5/10

The exact human strengths have current, traceable registrations in Georgia and Hungary, official product documents and an identifiable manufacturer. No veterinary famotidine product was found in the checked VMD register, so dog and cat use of these human tablets is off-label.

Clinical efficacy6.0/10

Controlled canine pH studies show short-term acid suppression with twice-daily famotidine, but it is inferior to omeprazole and repeated dosing loses effect within days; direct clinical healing-outcome evidence is limited and once-daily or empirical antiemetic use is unsupported.

Safety and tolerability7.0/10

Famotidine is generally well tolerated and the exact human label provides established contraindication, adverse-effect, interaction and renal-adjustment information. Veterinary use remains off-label; exposure rises with renal impairment, reproductive safety is not established for these animal uses, and prolonged treatment adds tolerance and rebound concerns.

Clinical practicality5.0/10

At 0.5 mg/kg twice daily, one whole 20 mg tablet corresponds to about a 40 kg dog. The current exact SPC describes whole swallowing and no validated score; smaller dogs usually need another strength or a pharmacy-compounded formulation, while twice-daily home administration is otherwise simple.

Full-course cost-effectiveness-

Comparable current full-course local prices were not verified.

Important safety and use flags

  • Do not use famotidine as a routine antiemetic or automatic cover for uncomplicated vomiting, gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs without an individual acid-related ulceration, erosion or reflux rationale.
  • Use a twice-daily evidence-based regimen when an H2 blocker is selected; once-daily H2-receptor antagonism lacks demonstrated benefit for gastroduodenal ulceration/erosion or reflux oesophagitis in dogs and cats.
  • Expect tachyphylaxis with repeated administration: canine loss of acid-suppressive effect can begin within days and is clear by about two weeks. Reassess early rather than escalating the dose or continuing an ineffective long course.
  • For sustained or potent acid suppression, proton-pump inhibitors generally outperform famotidine. Do not stack acid suppressants empirically; select one justified strategy and reassess the diagnosis and response.
  • Reduce or extend the dosing interval in clinically important renal impairment according to an appropriate reference and monitor response/adverse effects; famotidine is substantially renally eliminated. Use additional caution with hepatic dysfunction.
  • This exact 20 mg product is a whole film-coated tablet marked F20, not a validated scored veterinary dose unit. Do not estimate small animal doses from fragments or an unmeasured portion of crushed powder; use an appropriate strength or accurately compounded preparation.
  • Review concurrent medicines whose absorption depends on gastric pH, including azole antifungals, and drugs affected by renal clearance. Separate or change therapy only using product-specific interaction guidance.
  • Avoid use after hypersensitivity to famotidine or another component. Veterinary pregnancy, lactation and breeding safety for these exact human tablets is not established; use only after an individual benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis
5.7/10
Situational / acceptable
vetman assessment

Kvamatel

20 mg, tablet, human medicine
Assessed clinical scopeCat · Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis · By mouth
Care settingVeterinary-directed short course in hospital or at home, normally twice daily, with diagnosis, response, renal function, duration and a more effective proton-pump inhibitor option reassessed.
vetman score 5.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043672 · Verified on 15 Oct 2026 Off-label use

Famotidine can suppress feline gastric acid short term, but this whole 20 mg human tablet cannot accurately provide the usual cat dose and is less effective than omeprazole. The low score reflects the exact presentation as well as the limited role.

Regulatory and scientific credibility6.5/10

The exact human strengths have current, traceable registrations in Georgia and Hungary, official product documents and an identifiable manufacturer. No veterinary famotidine product was found in the checked VMD register, so dog and cat use of these human tablets is off-label.

Clinical efficacy5.5/10

A small controlled feline crossover study shows twice-daily oral famotidine raises intragastric pH above placebo, but it is inferior to omeprazole. Evidence is mainly short-term physiology in healthy cats, tolerance develops with repeated use, and clinical healing outcomes remain uncertain.

Safety and tolerability7.0/10

Famotidine is generally well tolerated and the exact human label provides established contraindication, adverse-effect, interaction and renal-adjustment information. Veterinary use remains off-label; exposure rises with renal impairment, reproductive safety is not established for these animal uses, and prolonged treatment adds tolerance and rebound concerns.

Clinical practicality2.5/10

The studied feline dose is about 0.88-1.26 mg/kg twice daily, roughly 3.5-5 mg for a 4 kg cat. A whole-only 20 mg tablet cannot deliver that dose accurately; use an appropriate lower-strength or pharmacy-compounded formulation rather than estimating fragments or crushed powder.

Full-course cost-effectiveness-

Comparable current full-course local prices were not verified.

Important safety and use flags

  • Do not use famotidine as a routine antiemetic or automatic cover for uncomplicated vomiting, gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs without an individual acid-related ulceration, erosion or reflux rationale.
  • Use a twice-daily evidence-based regimen when an H2 blocker is selected; once-daily H2-receptor antagonism lacks demonstrated benefit for gastroduodenal ulceration/erosion or reflux oesophagitis in dogs and cats.
  • Expect tachyphylaxis with repeated administration: canine loss of acid-suppressive effect can begin within days and is clear by about two weeks. Reassess early rather than escalating the dose or continuing an ineffective long course.
  • For sustained or potent acid suppression, proton-pump inhibitors generally outperform famotidine. Do not stack acid suppressants empirically; select one justified strategy and reassess the diagnosis and response.
  • Reduce or extend the dosing interval in clinically important renal impairment according to an appropriate reference and monitor response/adverse effects; famotidine is substantially renally eliminated. Use additional caution with hepatic dysfunction.
  • This exact 20 mg product is a whole film-coated tablet marked F20, not a validated scored veterinary dose unit. Do not estimate small animal doses from fragments or an unmeasured portion of crushed powder; use an appropriate strength or accurately compounded preparation.
  • Review concurrent medicines whose absorption depends on gastric pH, including azole antifungals, and drugs affected by renal clearance. Separate or change therapy only using product-specific interaction guidance.
  • Avoid use after hypersensitivity to famotidine or another component. Veterinary pregnancy, lactation and breeding safety for these exact human tablets is not established; use only after an individual benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Famotidine20 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Gedeon Richter · Hungary
Registration
Georgia Yes, human
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Kvamatel 40 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis
6.0/10
Situational / acceptable
vetman assessment

Kvamatel

40 mg, tablet, human medicine
Assessed clinical scopeDog · Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis · By mouth
Care settingVeterinary-directed short course in hospital or at home, normally twice daily, with diagnosis, response, renal function, duration and a more effective proton-pump inhibitor option reassessed.
vetman score 6.0/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043673 · Verified on 15 Oct 2026 Off-label use

A credible short-term H2 blocker in a transparent human product, but the whole 40 mg unit fits only an exceptional very large dog and famotidine loses effect with repeated dosing. A more suitable strength or formulation is usually preferable.

Regulatory and scientific credibility6.5/10

The exact human strengths have current, traceable registrations in Georgia and Hungary, official product documents and an identifiable manufacturer. No veterinary famotidine product was found in the checked VMD register, so dog and cat use of these human tablets is off-label.

Clinical efficacy6.0/10

Controlled canine pH studies show short-term acid suppression with twice-daily famotidine, but it is inferior to omeprazole and repeated dosing loses effect within days; direct clinical healing-outcome evidence is limited and once-daily or empirical antiemetic use is unsupported.

Safety and tolerability7.0/10

Famotidine is generally well tolerated and the exact human label provides established contraindication, adverse-effect, interaction and renal-adjustment information. Veterinary use remains off-label; exposure rises with renal impairment, reproductive safety is not established for these animal uses, and prolonged treatment adds tolerance and rebound concerns.

Clinical practicality3.5/10

At 0.5 mg/kg twice daily, one whole 40 mg tablet corresponds to about an 80 kg dog. The current exact SPC describes whole swallowing and no validated score, so this strength rarely fits a canine dose without an accurately compounded alternative.

Full-course cost-effectiveness-

Comparable current full-course local prices were not verified.

Important safety and use flags

  • Do not use famotidine as a routine antiemetic or automatic cover for uncomplicated vomiting, gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs without an individual acid-related ulceration, erosion or reflux rationale.
  • Use a twice-daily evidence-based regimen when an H2 blocker is selected; once-daily H2-receptor antagonism lacks demonstrated benefit for gastroduodenal ulceration/erosion or reflux oesophagitis in dogs and cats.
  • Expect tachyphylaxis with repeated administration: canine loss of acid-suppressive effect can begin within days and is clear by about two weeks. Reassess early rather than escalating the dose or continuing an ineffective long course.
  • For sustained or potent acid suppression, proton-pump inhibitors generally outperform famotidine. Do not stack acid suppressants empirically; select one justified strategy and reassess the diagnosis and response.
  • Reduce or extend the dosing interval in clinically important renal impairment according to an appropriate reference and monitor response/adverse effects; famotidine is substantially renally eliminated. Use additional caution with hepatic dysfunction.
  • This exact 40 mg product is a whole film-coated tablet marked F40, not a validated scored veterinary dose unit. Do not estimate small animal doses from fragments or an unmeasured portion of crushed powder; use an appropriate strength or accurately compounded preparation.
  • Review concurrent medicines whose absorption depends on gastric pH, including azole antifungals, and drugs affected by renal clearance. Separate or change therapy only using product-specific interaction guidance.
  • Avoid use after hypersensitivity to famotidine or another component. Veterinary pregnancy, lactation and breeding safety for these exact human tablets is not established; use only after an individual benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis
5.5/10
Situational / acceptable
vetman assessment

Kvamatel

40 mg, tablet, human medicine
Assessed clinical scopeCat · Short-term oral acid suppression for suspected or documented gastroduodenal ulceration/erosion or reflux oesophagitis when famotidine is deliberately selected; not routine treatment of vomiting or nonspecific prophylaxis · By mouth
Care settingVeterinary-directed short course in hospital or at home, normally twice daily, with diagnosis, response, renal function, duration and a more effective proton-pump inhibitor option reassessed.
vetman score 5.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043673 · Verified on 15 Oct 2026 Off-label use

Famotidine can suppress feline gastric acid short term, but this whole 40 mg human tablet is fundamentally unsuitable for accurate feline dosing and is less effective than omeprazole. Choose a dose-appropriate formulation when an H2 blocker is justified.

Regulatory and scientific credibility6.5/10

The exact human strengths have current, traceable registrations in Georgia and Hungary, official product documents and an identifiable manufacturer. No veterinary famotidine product was found in the checked VMD register, so dog and cat use of these human tablets is off-label.

Clinical efficacy5.5/10

A small controlled feline crossover study shows twice-daily oral famotidine raises intragastric pH above placebo, but it is inferior to omeprazole. Evidence is mainly short-term physiology in healthy cats, tolerance develops with repeated use, and clinical healing outcomes remain uncertain.

Safety and tolerability7.0/10

Famotidine is generally well tolerated and the exact human label provides established contraindication, adverse-effect, interaction and renal-adjustment information. Veterinary use remains off-label; exposure rises with renal impairment, reproductive safety is not established for these animal uses, and prolonged treatment adds tolerance and rebound concerns.

Clinical practicality1.5/10

The studied feline dose is about 0.88-1.26 mg/kg twice daily, roughly 3.5-5 mg for a 4 kg cat. A whole-only 40 mg tablet is profoundly mismatched and cannot deliver that dose accurately; an appropriate lower-strength or pharmacy-compounded formulation is required.

Full-course cost-effectiveness-

Comparable current full-course local prices were not verified.

Important safety and use flags

  • Do not use famotidine as a routine antiemetic or automatic cover for uncomplicated vomiting, gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs without an individual acid-related ulceration, erosion or reflux rationale.
  • Use a twice-daily evidence-based regimen when an H2 blocker is selected; once-daily H2-receptor antagonism lacks demonstrated benefit for gastroduodenal ulceration/erosion or reflux oesophagitis in dogs and cats.
  • Expect tachyphylaxis with repeated administration: canine loss of acid-suppressive effect can begin within days and is clear by about two weeks. Reassess early rather than escalating the dose or continuing an ineffective long course.
  • For sustained or potent acid suppression, proton-pump inhibitors generally outperform famotidine. Do not stack acid suppressants empirically; select one justified strategy and reassess the diagnosis and response.
  • Reduce or extend the dosing interval in clinically important renal impairment according to an appropriate reference and monitor response/adverse effects; famotidine is substantially renally eliminated. Use additional caution with hepatic dysfunction.
  • This exact 40 mg product is a whole film-coated tablet marked F40, not a validated scored veterinary dose unit. Do not estimate small animal doses from fragments or an unmeasured portion of crushed powder; use an appropriate strength or accurately compounded preparation.
  • Review concurrent medicines whose absorption depends on gastric pH, including azole antifungals, and drugs affected by renal clearance. Separate or change therapy only using product-specific interaction guidance.
  • Avoid use after hypersensitivity to famotidine or another component. Veterinary pregnancy, lactation and breeding safety for these exact human tablets is not established; use only after an individual benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Famotidine40 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Gedeon Richter · Hungary
Registration
Georgia Yes, human
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Quamatel, Powder

Kvamatel 20 mg, powder for solution for injection, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Short-term hospital IV acid suppression when oral therapy is impossible and acid-related gastroduodenal erosion/ulcer or reflux oesophagitis is suspected or confirmed; not routine antiemesis or nonspecific prophylaxis
6.4/10
Situational / acceptable
vetman assessment

Quamatel

Kvamatel 20 mg, powder for solution for injection, human medicine
Assessed clinical scopeDog · Short-term hospital IV acid suppression when oral therapy is impossible and acid-related gastroduodenal erosion/ulcer or reflux oesophagitis is suspected or confirmed; not routine antiemesis or nonspecific prophylaxis · Intravenous
Care settingVeterinary hospital use with diagnosis, exact reconstitution, slow administration or infusion, renal review, objective response monitoring and early oral/PPI strategy reassessment
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043674 · Verified on 22 Oct 2026 Off-label use

A transparent, accurately reconstituted hospital IV option with direct canine acid-suppression evidence, but not a routine antiemetic or a first-choice sustained acid suppressant. The direct evidence is physiologic, regimen-dependent and not an exact-product healing trial.

Regulatory and scientific credibility6.5/10

The exact 20 mg vial, 5 ml solvent, 4 mg/ml reconstituted concentration, holder and IV-only human label are traceable in current GE and Lithuanian records. Veterinary use is off-label and no exact veterinary dossier exists.

Clinical efficacy6.0/10

Randomised healthy-dog IV pH studies show significant short-term acid suppression; a high-dose CRI met human-derived healing pH targets, while intermittent dosing did not. No diseased-dog healing, bleeding, quality-of-life or exact-product outcome trial exists.

Safety and tolerability6.5/10

Human exact-label safety and veterinary class experience are substantial, but exact-product dog repeated-dose, diseased-subgroup and reproductive data are absent. Renal accumulation, hypersensitivity, infusion handling and route-related events require review.

Clinical practicality7.0/10

The supplied solvent creates a known 4 mg/ml solution suitable for monitored IV measurement, but use requires reconstitution, hospital administration, slow injection or infusion, asepsis, compatibility review and immediate microbiological use. Exact-product SC administration is unsupported.

Full-course cost-effectiveness-

Exact current Georgian course price and availability were not verified; duration and intermittent-versus-CRI resource use are indication-dependent, so cost is excluded.

Important safety and use flags

  • This is a human medicine. Every dog/cat use is off-label and requires an individual veterinary benefit-risk and dose decision. Exact-product veterinary pregnancy, lactation, neonatal and long-term repeated-dose safety are not established.
  • Use only for a specific acid-related erosion, ulcer or reflux rationale when oral therapy is unsuitable. Do not use as a routine antiemetic or automatic cover for gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs.
  • Twice-daily proton-pump inhibitor treatment generally provides stronger sustained acid suppression. Reassess early whether famotidine is the right strategy.
  • Do not stack famotidine with a PPI empirically; controlled evidence does not show an ulcer-healing advantage and the combination may reduce PPI effectiveness.
  • Intermittent famotidine loses acid-suppressive effect with continued exposure. If treatment continues, reassess diagnosis, pH/healing objective, response and transition strategy rather than escalating blindly.
  • The exact human label is IV-only. Generic clinical SC famotidine exposure does not make SC an authorised or exact-product-supported route.
  • In cats, the reassuring haemolysis study used slow IV administration over five minutes. It supports route safety, not efficacy or rapid bolus administration.
  • Reconstitute the 20 mg vial exactly with the supplied 5 ml solvent to obtain 4 mg/ml. Verify clarity, compatibility, asepsis, injection/infusion rate and immediate microbiological use.
  • Famotidine is substantially renally cleared. Review renal function, accumulation and interval/dose adjustment; also reassess hepatic disease and interacting absorption-sensitive medicines.
  • Contraindicated after hypersensitivity to famotidine, another H2-receptor antagonist or any exact-product excipient.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Short-term hospital IV acid suppression when oral therapy is impossible and acid-related gastroduodenal erosion/ulcer or reflux oesophagitis is suspected or confirmed; not routine antiemesis or nonspecific prophylaxis
6.0/10
Situational / acceptable
vetman assessment

Quamatel

Kvamatel 20 mg, powder for solution for injection, human medicine
Assessed clinical scopeCat · Short-term hospital IV acid suppression when oral therapy is impossible and acid-related gastroduodenal erosion/ulcer or reflux oesophagitis is suspected or confirmed; not routine antiemesis or nonspecific prophylaxis · Intravenous
Care settingVeterinary hospital use with diagnosis, exact reconstitution, slow administration or infusion, renal review, objective response monitoring and early oral/PPI strategy reassessment
vetman score 6.0/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043674 · Verified on 22 Oct 2026 Off-label use

A transparent hospital IV formulation with reassuring slow-IV feline safety data, but injectable feline efficacy remains indirect and PPIs are generally stronger. Use only for a specific acid-related indication when oral therapy is unsuitable.

Regulatory and scientific credibility6.5/10

The exact 20 mg vial, 5 ml solvent, 4 mg/ml reconstituted concentration, holder and IV-only human label are traceable in current GE and Lithuanian records. Veterinary use is off-label and no exact veterinary dossier exists.

Clinical efficacy4.0/10

Cats have controlled oral pH evidence showing short-term effect inferior to omeprazole and route-specific IV safety exposure, but no feline injectable pH-efficacy or clinical-healing trial. Efficacy of this exact IV product is therefore indirect.

Safety and tolerability7.0/10

In 142 hospitalised cats, slow IV famotidine was not associated with haemolysis or a greater PCV decline than SC or control exposure, directly addressing a common concern. This retrospective study does not establish all uncommon, repeated-dose, reproductive or exact-product risks.

Clinical practicality7.0/10

The supplied solvent creates a known 4 mg/ml solution suitable for monitored IV measurement, but use requires reconstitution, hospital administration, slow injection or infusion, asepsis, compatibility review and immediate microbiological use. Exact-product SC administration is unsupported.

Full-course cost-effectiveness-

Exact current Georgian course price and availability were not verified; duration and intermittent-versus-CRI resource use are indication-dependent, so cost is excluded.

Important safety and use flags

  • This is a human medicine. Every dog/cat use is off-label and requires an individual veterinary benefit-risk and dose decision. Exact-product veterinary pregnancy, lactation, neonatal and long-term repeated-dose safety are not established.
  • Use only for a specific acid-related erosion, ulcer or reflux rationale when oral therapy is unsuitable. Do not use as a routine antiemetic or automatic cover for gastritis, pancreatitis, renal disease, hepatic disease, corticosteroids or NSAIDs.
  • Twice-daily proton-pump inhibitor treatment generally provides stronger sustained acid suppression. Reassess early whether famotidine is the right strategy.
  • Do not stack famotidine with a PPI empirically; controlled evidence does not show an ulcer-healing advantage and the combination may reduce PPI effectiveness.
  • Intermittent famotidine loses acid-suppressive effect with continued exposure. If treatment continues, reassess diagnosis, pH/healing objective, response and transition strategy rather than escalating blindly.
  • The exact human label is IV-only. Generic clinical SC famotidine exposure does not make SC an authorised or exact-product-supported route.
  • In cats, the reassuring haemolysis study used slow IV administration over five minutes. It supports route safety, not efficacy or rapid bolus administration.
  • Reconstitute the 20 mg vial exactly with the supplied 5 ml solvent to obtain 4 mg/ml. Verify clarity, compatibility, asepsis, injection/infusion rate and immediate microbiological use.
  • Famotidine is substantially renally cleared. Review renal function, accumulation and interval/dose adjustment; also reassess hepatic disease and interacting absorption-sensitive medicines.
  • Contraindicated after hypersensitivity to famotidine, another H2-receptor antagonist or any exact-product excipient.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Famotidine20 mg
Formulation Type
Powder
Administration route
Intravenous
Manufacturer
Registration
Georgia Yes, human
In force until 22 Jul 2030
Human (Ministry of Health, RAMA)
№ რ-043674
Verified on: 22 Oct 2026
EU Yes, human
№ LT/1/94/1030/003
Verified on: 22 Oct 2026
UK Not confirmed
Verified on: 22 Oct 2026
US Not confirmed
Verified on: 22 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified Exact human label: 20 mg/vial; reconstitution with the supplied 5 ml solvent gives 4 mg/ml; IV only, slow injection or infusion in hospital, with oral transition when feasible. Veterinary intermittent and CRI regimens have different evidence and must not be collapsed into one unrestricted calculator.

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.