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Cerenia

Maropitant · Zoetis

1 form: solution. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Form Dose Frequency Georgia
Solution 1 mg/kg
For dogs and cats, give 1 mg/kg, equivalent to 1 mL/10 kg, subcutaneously or intravenously once daily for no more than 5 consecutive days. For IV use, give as a single bolus without mixing with other fluids. For prevention of vomiting, administer at least 1 hour before the event. Transient pain is common after subcutaneous injection; chilled solution may reduce it.
· once daily, maximum 5 days
once daily, maximum 5 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სერენია – 10მგ/მლ საინექციო ხსნარი ძაღლებისა და კატებისათვის
№ 251-11
Verified on: 18 Oct 2026
Details: pack, label wording, sources, registration

Cerenia, Solution

Maropitant 10 mg/ml, solution for injection
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Labelled prevention and treatment of nausea and vomiting in dogs, excluding motion sickness, with diagnosis and supportive care as indicated
8.4/10
Very good
vetman assessment

Cerenia

Maropitant 10 mg/ml, solution for injection
Assessed clinical scopeDog · Labelled prevention and treatment of nausea and vomiting in dogs, excluding motion sickness, with diagnosis and supportive care as indicated · SC,IV
Care settingVeterinary clinic or hospital, including perioperative and supportive-care use
vetman score 8.4/10 Very good
Evidence confidence: Medium Georgia: Yes, veterinary · № 251-11 · Verified on 18 Oct 2026

A strong standard injectable antiemetic for dogs with excellent regulatory transparency; diagnostic work-up and treatment of the cause remain indispensable.

Regulatory and scientific credibility9.0/10

The exact 10 mg/ml dog-and-cat injection has a current transparent EU centrally authorised SPC and active Georgian veterinary registration (251-11).

Clinical efficacy8.5/10

Maropitant is a well-established NK1 antiemetic with labelled preventive and therapeutic roles across common veterinary nausea and vomiting contexts; it controls the symptom, not the underlying cause.

Safety and tolerability8.0/10

Usually well tolerated under labelled use, but injection pain, accumulation with repeated dosing and cautions in young, hepatic, cardiac, pregnant or lactating patients require selection and monitoring.

Clinical practicality8.0/10

Once-daily SC or IV dosing for up to five days is straightforward in clinic; IV must be a separate bolus and SC discomfort should be anticipated.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use concurrently with calcium-channel antagonists according to the reviewed class label.
  • Use cautiously in hepatic or cardiac disease and in pregnancy or lactation; safety is not established below 8 weeks.
  • Vomiting can signal obstruction or other serious disease; suppressing it never replaces diagnostic evaluation and causal/supportive treatment.
Assessment sources
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Labelled prevention and treatment of nausea and vomiting in cats, excluding motion sickness, with diagnosis and supportive care as indicated
8.1/10
Very good
vetman assessment

Cerenia

Maropitant 10 mg/ml, solution for injection
Assessed clinical scopeCat · Labelled prevention and treatment of nausea and vomiting in cats, excluding motion sickness, with diagnosis and supportive care as indicated · SC,IV
Care settingVeterinary clinic or hospital, including supportive care for systemic disease
vetman score 8.1/10 Very good
Evidence confidence: Medium Georgia: Yes, veterinary · № 251-11 · Verified on 18 Oct 2026

A very good labelled injectable antiemetic for cats, with clear limits: it treats nausea and vomiting, not appetite loss or the underlying disease.

Regulatory and scientific credibility9.0/10

The exact 10 mg/ml dog-and-cat injection has a current transparent EU centrally authorised SPC and active Georgian veterinary registration (251-11).

Clinical efficacy8.0/10

Maropitant reliably reduces feline vomiting and nausea in labelled settings; in CKD it may reduce vomiting without improving appetite or weight, so it is not a substitute for appetite-directed therapy or causal treatment.

Safety and tolerability7.5/10

Labelled use is generally tolerable, but safety is not established below 16 weeks and hepatic, cardiac, reproductive and repeated-dose cautions are clinically relevant.

Clinical practicality7.5/10

Once-daily SC or IV clinic dosing is feasible, but feline restraint, SC pain and the five-day labelled limit can materially affect repeated treatment.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use concurrently with calcium-channel antagonists according to the reviewed class label.
  • Use cautiously in hepatic or cardiac disease and in pregnancy or lactation; safety is not established below 16 weeks.
  • Vomiting can signal obstruction or serious disease; maropitant does not replace diagnosis, supportive care or appetite-directed treatment.
Assessment sources
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Maropitant10 mg/ml
Formulation Type
Solution
Administration route
Subcutaneous, Intravenous
Manufacturer
Zoetis · United States
Manufacturer (register)
ZOETIS MANUFACTURING & RESEARCH SPAIN, S.L., Spain
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 903, 19 Oct 2026.
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სერენია – 10მგ/მლ საინექციო ხსნარი ძაღლებისა და კატებისათვის
№ 251-11
Verified on: 18 Oct 2026
EU Yes, veterinary
Verified on: 15 Oct 2026
UK Yes, veterinary
Verified on: 15 Oct 2026
US Yes, veterinary
№ NADA 141-263
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 mg/kg
For dogs and cats, give 1 mg/kg, equivalent to 1 mL/10 kg, subcutaneously or intravenously once daily for no more than 5 consecutive days. For IV use, give as a single bolus without mixing with other fluids. For prevention of vomiting, administer at least 1 hour before the event. Transient pain is common after subcutaneous injection; chilled solution may reduce it.
All species Any weight SC,IV once daily, maximum 5 days
UPD SPC 2024
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
CERENIA 10 mg/ml solution for injection for dogs and cats - SPC (EU centralised authorisation)
EU Union Product Database, 2024
Active substance doses, with sources
Active substance Maropitant
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
1 mg/kg Dog, Cat Vomiting Intravenous / Subcutaneous once daily
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Vetemex 10 mg/ml Solution for Injection for Dogs and Cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024

Known Contraindications

  • Warning
    Maropitant is metabolised in the liver and therefore should be used with caution in patients with hepatic disease. As maropitant is accumulated in the body during a 14 day treatment period due to metabolic saturation, careful monitoring of liver function and any adverse events should be implemented during long term treatment.
    Sources: VMD SPC · VMD
  • Warning
    The veterinary medicinal product should be used with caution in animals suffering from or with predisposition for cardiac diseases as maropitant has affinity to Ca- and K-ion channels.
    Sources: VMD SPC · VMD
  • Warning
    Vomiting can be associated with serious, severely debilitating conditions including gastrointestinal obstructions; therefore, appropriate diagnostic evaluations should be employed.
    Sources: VMD SPC · VMD
  • Warning
    Use only according to the benefit-risk assessment by the responsible veterinarian, because conclusive reproductive toxicity studies have not been conducted in any animal species.
    Sources: VMD SPC · VMD
  • Warning
    The safety of maropitant has not been established in... pregnant or lactating dogs and cats.
    Sources: VMD SPC · VMD
  • Warning (Dog)
    The safety of maropitant has not been established in dogs less than 8 weeks of age, or in cats less than 16 weeks of age.
    Sources: VMD SPC · VMD
  • Warning (Cat)
    The safety of maropitant has not been established in dogs less than 8 weeks of age, or in cats less than 16 weeks of age.
    Sources: VMD SPC · VMD

Known Drug Interactions

  • Major warning Amlodipine + Maropitant
    The veterinary medicinal product should not be used concomitantly with Ca-channel antagonists as maropitant has affinity to Ca-channels.
    Recommendation: None
    Sources: VMD SPC · VMD

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.