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Product

Dexamethasone Krka

Dexamethasone · Krka

2 forms: solution, tablet. In force in Georgia: 2 of 2 (human register).

Forms and doses2 of 2 in force in Georgia

Form Dose Frequency Georgia
0.5 mg, Tablet No label dose in the reference yet - Georgia Yes, human
In force until 25 Feb 2030
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 0.5 მგ, აბი
№ რ-042830
Verified on: 16 Oct 2026
Details: pack, label wording, sources, registration

Dexamethasone Krka 0.5 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.7/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

0.5 mg, tablet, human medicine
Assessed clinical scopeDog · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042830 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 0.5 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, an identifiable current UK SmPC and no exact US registration in the checked register. Veterinary use remains off-label, although an authorised veterinary 0.5 mg oral comparator directly supports species, route and strength.

Clinical efficacy7.5/10

Dexamethasone is a potent, well-absorbed, long-acting oral glucocorticoid, and a current authorised veterinary 0.5 mg product directly supports symptomatic or adjunct treatment of inflammatory and allergic disease in dogs. It can provide strong short-term control when the diagnosis and dose target are correct, but does not cure the underlying disease and is usually less suitable than a shorter-acting steroid for adjustable chronic therapy.

Safety and tolerability5.0/10

Short, appropriately selected courses can be manageable, but cortisol suppression is very common with the authorised veterinary comparator and long-acting dexamethasone can cause infection, gastrointestinal ulceration, metabolic effects, delayed healing and HPA-axis suppression. Long-term oral use is specifically discouraged when a shorter-acting alternative such as prednisolone can provide control.

Clinical practicality6.0/10

A 0.5 mg whole-tablet unit is compact and simple to store and can fit some small-to-medium canine doses, but this human tablet is not the flavoured, quarterable veterinary comparator. The exact instruction does not establish fractional veterinary dosing, so smaller increments or many-tablet regimens require a more suitable strength or validated compound.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.7/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

0.5 mg, tablet, human medicine
Assessed clinical scopeCat · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042830 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 0.5 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, an identifiable current UK SmPC and no exact US registration in the checked register. Veterinary use remains off-label, although an authorised veterinary 0.5 mg oral comparator directly supports species, route and strength.

Clinical efficacy7.5/10

A current authorised veterinary 0.5 mg product directly supports oral dexamethasone for inflammatory and allergic disease in cats, and a small prospective feline study found oral absorption and improvement in hypersensitivity dermatitis. The evidence supports useful short-term control, not every possible immune-mediated claim; response is diagnosis-dependent and treatment must remain adjunctive to cause control.

Safety and tolerability4.5/10

The authorised veterinary label documents very common cortisol suppression and broad glucocorticoid toxicity. In cats, controlled pilot data suggest greater diabetogenic effects than equipotent prednisolone, while prolonged immunosuppressive exposure can produce hyperglycaemia, infection, hepatopathy, skin/muscle change, gastrointestinal injury and adrenal suppression; this narrows the margin for chronic use.

Clinical practicality7.0/10

A 0.5 mg whole-tablet unit often fits clinically relevant feline dosing better than higher human strengths and is simple to store. It is nevertheless an unflavoured human tablet without the veterinary comparator’s validated quarter divisions; cats needing smaller increments, reluctant pill-takers and multi-step tapers may require a more suitable veterinary or compounded form.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Krka · Slovenia
Registration
Georgia Yes, human
In force until 25 Feb 2030
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 0.5 მგ, აბი
№ რ-042830
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL001421313, PL016560205, PL016560206, PL016560207
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
4 mg/ml, Solution No label dose in the reference yet - Georgia Yes, human
In force until 16 Apr 2031
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 4 მგ/მლ, 1 მლ ამპულა
№ რ-045250
Verified on: 16 Oct 2026
Details: pack, label wording, sources, registration

Dexamethasone Krka 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045250 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045250 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Krka · Slovenia
Registration
Georgia Yes, human
In force until 16 Apr 2031
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 4 მგ/მლ, 1 მლ ამპულა
№ რ-045250
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL001421313, PL016560205, PL016560206, PL016560207
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Active substance doses, with sources

Each dose comes with its source. Check the label of the product you use.

Active substance Dexamethasone
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
0.05–0.2 mg/kg Dog Inflammation By mouth once daily in the morning
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Dexacortone 0.5 mg and 2.0 mg Chewable Tablets for Dogs and Cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
0.1 mg/kg Dog, Cat Allergic Reaction Intramuscular as needed
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Dexadreson 2 mg/ml Solution for Injection - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
0.05–0.2 mg/kg Cat Inflammation By mouth once daily in the evening
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Dexacortone 0.5 mg and 2.0 mg Chewable Tablets for Dogs and Cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Known Contraindications

  • Critical
    Do not use corticosteroids, topically or systemically, while a corneal ulcer is present. They slow healing of the corneal epithelium and can increase collagenase activity, which may turn the ulcer into a melting ulcer.
    Sources: MSD Vet Manual
  • Critical
    Do not use dexamethasone in animals with diabetes mellitus or hyperadrenocorticism unless specifically required and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with diabetes mellitus or hyperadrenocorticism.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with osteoporosis because corticosteroids increase protein catabolism and can reduce bone mass.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with cardiac or renal dysfunction, including congestive heart failure, unless specifically required and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    the product should not be used in animals suffering from diabetes, chronic nephritis, renal disease, congestive heart failure, osteoporosis and in viral infections during the viraemic stage
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with cardiac or renal dysfunction.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with gastro-intestinal ulceration.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with glaucoma.
    Sources: VMD SPC · VMD
  • Critical
    Do not use systemic dexamethasone in animals with burns unless specifically indicated and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone during pregnancy because early exposure can cause fetal abnormalities and late exposure can induce abortion or premature parturition.
    Sources: VMD SPC · VMD
  • Critical
    Known hypersensitivity to dexamethasone, another corticosteroid, or any excipient is a contraindication.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with viral or mycotic infections.
    Sources: VMD SPC · VMD
  • Warning
    Use with particular caution in an immunocompromised patient because corticosteroids delay wound healing and can exacerbate an existing infection.
    Sources: VMD SPC · VMD
  • Warning
    Corticoids such as dexamethasone should be used with caution in patients with hypertension.
    Sources: VMD SPC · VMD
  • Warning
    Since glucocorticosteroids are known to slow growth, use in young animals (under 7 months of age) should be based on a benefit/risk assessment by the attending veterinarian.
    Sources: VMD SPC · VMD
  • Warning
    Do not use concomitantly with attenuated alive vaccine dexamethasone should not be used in combination with vaccines or within two weeks after vaccination
    Sources: VMD SPC · VMD
  • Caution
    Due to the long duration of effect of dexamethasone alternate day therapy is not an adequate way to allow the hypothalamic-pituitary-adrenal axis to recover.
    Sources: VMD SPC · VMD
  • Caution
    Use cautiously in geriatric or debilitated animals because corticosteroids increase protein catabolism. Prolonged treatment can cause cushingoid changes, including fat redistribution, muscle weakness and atrophy, and osteoporosis.
    Sources: VMD SPC · VMD

Known Drug Interactions

  • Contraindicated Robenacoxib + Dexamethasone
    Do not give robenacoxib together with other non-steroidal anti-inflammatory drugs or glucocorticoids because adverse gastrointestinal and renal effects may increase.
    Recommendation: Do not use these drugs together. Allow a treatment-free interval of at least 24 hours after the previous anti-inflammatory drug, extending it when required by that drug’s pharmacokinetics.
  • Major warning Meloxicam + Dexamethasone
    The concomitant use of this veterinary medicinal product with non-steroidal anti-inflammatory drugs may exacerbate gastrointestinal tract ulceration.
    Recommendation: Avoid concurrent administration. Observe an appropriate washout period when switching. If both are essential, provide gastroprotection and monitor gastrointestinal signs closely.
    Sources: VMD SPC · VMD
  • Major warning Carprofen + Dexamethasone
    Do not give other non-steroidal anti-inflammatory drugs or glucocorticoids concurrently with carprofen or within 24 hours of treatment because gastrointestinal ulceration or perforation may occur.
    Recommendation: Consider appropriate washout times when switching from one NSAID to another or when switching from corticosteroid use to NSAID use.
    Sources: FDA
  • Major warning Dexamethasone + Insulin glargine
    Glucocorticoids, progestogens, and certain endocrinopathies can have an antagonistic effect on insulin activity. Glucocorticoid and progestogen use should be avoided.
    Recommendation: Avoid the combination. If the glucocorticoid cannot be discontinued within 2 weeks, the insulin dose may need to be increased; monitor glycaemia.
    Sources: FDA · AAHA
  • Major warning Dexamethasone + Insulin human
    Glucocorticoids, progestogens, and certain endocrinopathies can have an antagonistic effect on insulin activity. Glucocorticoid and progestogen use should be avoided.
    Recommendation: Avoid the combination. If the glucocorticoid cannot be discontinued within 2 weeks, the insulin dose may need to be increased; monitor glycaemia.
    Sources: FDA · AAHA
  • Minor warning Furosemide + Dexamethasone
    The risk of hypokalaemia may be increased if dexamethasone is administered together with potassium depleting diuretics.
    Recommendation: Monitor serum potassium. Hypokalaemia also increases cardiac glycoside toxicity.
    Sources: VMD SPC · VMD
  • Minor warning Dexamethasone + Torasemide
    The risk of hypokalaemia may be increased if dexamethasone is administered together with potassium depleting diuretics.
    Recommendation: Monitor serum potassium.
    Sources: VMD SPC · VMD

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.