Register
Medicines reference
Active substance

Dexamethasone

Glucocorticoid (long-acting). Registered in Georgia: 1 veterinary product and 20 human medicines. Forms: ear drops, eye drops, ointment, solution, tablet.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Dexamethasone
Before use

Safety information

Known Contraindications

  • Critical
    Do not use corticosteroids, topically or systemically, while a corneal ulcer is present. They slow healing of the corneal epithelium and can increase collagenase activity, which may turn the ulcer into a melting ulcer.
    Sources: MSD Vet Manual
  • Critical
    Do not use dexamethasone in animals with diabetes mellitus or hyperadrenocorticism unless specifically required and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with diabetes mellitus or hyperadrenocorticism.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with osteoporosis because corticosteroids increase protein catabolism and can reduce bone mass.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with cardiac or renal dysfunction, including congestive heart failure, unless specifically required and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    the product should not be used in animals suffering from diabetes, chronic nephritis, renal disease, congestive heart failure, osteoporosis and in viral infections during the viraemic stage
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with cardiac or renal dysfunction.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with gastro-intestinal ulceration.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone in animals with glaucoma.
    Sources: VMD SPC · VMD
  • Critical
    Do not use systemic dexamethasone in animals with burns unless specifically indicated and closely monitored.
    Sources: VMD SPC · VMD
  • Critical
    Do not use dexamethasone during pregnancy because early exposure can cause fetal abnormalities and late exposure can induce abortion or premature parturition.
    Sources: VMD SPC · VMD
  • Critical
    Known hypersensitivity to dexamethasone, another corticosteroid, or any excipient is a contraindication.
    Sources: VMD SPC · VMD
  • Critical
    Do not use in animals with viral or mycotic infections.
    Sources: VMD SPC · VMD
  • Warning
    Use with particular caution in an immunocompromised patient because corticosteroids delay wound healing and can exacerbate an existing infection.
    Sources: VMD SPC · VMD
  • Warning
    Corticoids such as dexamethasone should be used with caution in patients with hypertension.
    Sources: VMD SPC · VMD
  • Warning
    Since glucocorticosteroids are known to slow growth, use in young animals (under 7 months of age) should be based on a benefit/risk assessment by the attending veterinarian.
    Sources: VMD SPC · VMD
  • Warning
    Do not use concomitantly with attenuated alive vaccine dexamethasone should not be used in combination with vaccines or within two weeks after vaccination
    Sources: VMD SPC · VMD
  • Caution
    Due to the long duration of effect of dexamethasone alternate day therapy is not an adequate way to allow the hypothalamic-pituitary-adrenal axis to recover.
    Sources: VMD SPC · VMD
  • Caution
    Use cautiously in geriatric or debilitated animals because corticosteroids increase protein catabolism. Prolonged treatment can cause cushingoid changes, including fat redistribution, muscle weakness and atrophy, and osteoporosis.
    Sources: VMD SPC · VMD

Known Drug Interactions

  • Contraindicated Robenacoxib + Dexamethasone
    Do not give robenacoxib together with other non-steroidal anti-inflammatory drugs or glucocorticoids because adverse gastrointestinal and renal effects may increase.
    Recommendation: Do not use these drugs together. Allow a treatment-free interval of at least 24 hours after the previous anti-inflammatory drug, extending it when required by that drug’s pharmacokinetics.
  • Major warning Meloxicam + Dexamethasone
    The concomitant use of this veterinary medicinal product with non-steroidal anti-inflammatory drugs may exacerbate gastrointestinal tract ulceration.
    Recommendation: Avoid concurrent administration. Observe an appropriate washout period when switching. If both are essential, provide gastroprotection and monitor gastrointestinal signs closely.
    Sources: VMD SPC · VMD
  • Major warning Carprofen + Dexamethasone
    Do not give other non-steroidal anti-inflammatory drugs or glucocorticoids concurrently with carprofen or within 24 hours of treatment because gastrointestinal ulceration or perforation may occur.
    Recommendation: Consider appropriate washout times when switching from one NSAID to another or when switching from corticosteroid use to NSAID use.
    Sources: FDA
  • Major warning Dexamethasone + Insulin glargine
    Glucocorticoids, progestogens, and certain endocrinopathies can have an antagonistic effect on insulin activity. Glucocorticoid and progestogen use should be avoided.
    Recommendation: Avoid the combination. If the glucocorticoid cannot be discontinued within 2 weeks, the insulin dose may need to be increased; monitor glycaemia.
    Sources: FDA · AAHA
  • Major warning Dexamethasone + Insulin human
    Glucocorticoids, progestogens, and certain endocrinopathies can have an antagonistic effect on insulin activity. Glucocorticoid and progestogen use should be avoided.
    Recommendation: Avoid the combination. If the glucocorticoid cannot be discontinued within 2 weeks, the insulin dose may need to be increased; monitor glycaemia.
    Sources: FDA · AAHA
  • Minor warning Furosemide + Dexamethasone
    The risk of hypokalaemia may be increased if dexamethasone is administered together with potassium depleting diuretics.
    Recommendation: Monitor serum potassium. Hypokalaemia also increases cardiac glycoside toxicity.
    Sources: VMD SPC · VMD
  • Minor warning Dexamethasone + Torasemide
    The risk of hypokalaemia may be increased if dexamethasone is administered together with potassium depleting diuretics.
    Recommendation: Monitor serum potassium.
    Sources: VMD SPC · VMD
Latin name
Dexamethasone
Georgian name
დექსამეტაზონი
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
21 of 24 forms
Human medicines in Georgia
Alerdex, Axium-Opto, Dekort, Etacortilen, Kordexa, Medexol, Oftacortal, Ozurdex, Ronic
Human medicines with this substance in the Georgian register of medicines (Ministry of Health), checked on 18 Oct 2026. They are human medicines, not veterinary products; strengths and forms differ.
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration24

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Allerdex 1 mg/ml (0.1%), Eye drops

eye drops suspension 10 ml, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.7/10
Situational / acceptable
vetman assessment

Allerdex

1 mg/ml (0.1%), eye drops suspension 10 ml, human medicine
Assessed clinical scopeDog · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-039299 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy8.0/10

Topical 0.1% dexamethasone is a standard, cornea-penetrating veterinary corticosteroid for noninfectious anterior ocular inflammation. Current canine data support improvement in moderate-to-severe follicular conjunctivitis and combination therapy for chronic superficial keratitis, while established use covers anterior uveitis, immune-mediated keratitis and episcleritis; diagnosis and cause-directed therapy determine benefit.

Safety and tolerability6.0/10

Correctly selected use is usually locally tolerable, but corticosteroids delay epithelial healing, increase collagenase activity and can convert an occult abrasion into a melting ulcer. Repeated treatment can increase intraocular pressure, promote infection, cataract and steroid keratopathy, and systemic absorption with cortisol suppression is documented after four-times-daily dosing.

Clinical practicality7.5/10

A standard dropper gives a directly deliverable ocular dose, but the suspension must be shaken thoroughly before every use and ten-millilitre packaging increases post-opening waste for short courses. Frequent initial dosing, atraumatic restraint, avoiding tip contact, separating other drops and scheduled re-examination remain material treatment burdens.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Reassess the diagnosis urgently if blepharospasm, discharge, corneal clouding, focal staining, vision change or worsening redness appears; stop dexamethasone until ulceration and infection have been excluded.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.1/10
Situational / acceptable
vetman assessment

Allerdex

1 mg/ml (0.1%), eye drops suspension 10 ml, human medicine
Assessed clinical scopeCat · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-039299 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy7.0/10

Topical 0.1% dexamethasone is an established cornea-penetrating corticosteroid for selected noninfectious feline anterior ocular inflammation, including immune-mediated keratitis, conjunctival disease and anterior uveitis. Direct controlled feline efficacy data are limited, and latent FHV-1 or infectious disease can make an apparently inflammatory presentation steroid-inappropriate.

Safety and tolerability5.0/10

Corneal ulceration or untreated infection creates a serious local hazard, and feline herpesvirus may reactivate with topical steroid exposure, causing ulceration or sequestrum. Longer treatment can increase intraocular pressure, delay healing, promote infection or cataract and cause systemic glucocorticoid exposure; feline product-specific safety data are limited.

Clinical practicality7.5/10

A standard dropper gives a directly deliverable ocular dose, but the suspension must be shaken thoroughly before every use and ten-millilitre packaging increases post-opening waste for short courses. Frequent initial dosing, atraumatic restraint, avoiding tip contact, separating other drops and scheduled re-examination remain material treatment burdens.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Topical corticosteroids can reactivate latent feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum. In a cat with compatible history or dendritic/geographic disease, stop steroid treatment and investigate/treat FHV-associated disease before considering further immunosuppression.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Registration
Georgia Yes, human
In force until 10 Oct 2028
Human (Ministry of Health, RAMA)
In the register: ალერდექსი 1 მგ/მლ (0.1%), თვალის წვეთები სუსპენზია 10 მლ
№ რ-039299
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Aurizon 3 mg/ml + 10 mg/ml + 0.9 mg/ml, Ear drops

ear drops suspension, for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.8/10
Good
vetman assessment

Aurizon

3 mg/ml + 10 mg/ml + 0.9 mg/ml, ear drops suspension, for dogs
Assessed clinical scopeDog · Label-concordant treatment of canine otitis externa caused by marbofloxacin-susceptible bacteria and clotrimazole-susceptible fungi, especially Malassezia pachydermatis, with concurrent control of inflammation · Into the ear
Care settingVeterinary diagnosis and selection after otoscopy and cytology; outpatient administration after cleaning and drying, with day-7 veterinary reassessment and investigation of the underlying cause.
vetman score 7.8/10 Good
Evidence confidence: High Georgia: No · Verified on 15 Oct 2026

A good, evidence-supported once-daily reference option for correctly diagnosed mixed bacterial/fungal canine otitis externa. Its fluoroquinolone component prevents routine first-line use: confirm an intact tympanum, base selection on cytology and susceptibility context, and investigate the underlying disease.

Regulatory and scientific credibility9.0/10

Aurizon is the long-established reference product with current exact EU/EEA and GB veterinary authorisations, a current regulator-hosted SPC, post-authorisation history and direct comparative trials. It is not registered in the checked Georgian or US registers.

Clinical efficacy7.5/10

A 140-dog phase III comparison found the marbofloxacin/clotrimazole/dexamethasone suspension equivalent to an established comparator, with a 58.3% cure rate and advantages in pain, discharge, odour and day-14 assessment. A bilateral Malassezia study also found greater improvement in yeast count, erythema, cerumen and pruritus than antifungal monotherapy. Benefit depends on matching cytology/pathogen susceptibility and addressing the primary cause.

Safety and tolerability7.0/10

Topical exposure is much lower than systemic treatment, but the intact tympanic membrane must be confirmed. Rare mostly transient deafness, local irritation and corticosteroid-related skin thinning, delayed healing, laboratory changes or adrenal suppression are possible; avoid pregnancy/lactation and unnecessary use in growing dogs.

Clinical practicality7.5/10

Ten drops once daily for 7-14 days is simpler than twice-daily alternatives, and the current packs provide one cannula per intended patient. The ear must still be examined, cleaned and dried, the suspension shaken and massaged in, and continuation beyond day 7 requires veterinary reassessment; in-use shelf life is two months.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform otoscopy and verify an intact tympanic membrane before every course. Do not use with a perforated or unvisualised tympanum; stop and reassess urgently for head tilt, nystagmus, ataxia, hearing change or other vestibular signs.
  • Cytology is required in every otitis externa case and should be repeated at recheck. Sample before cleaning; identify and manage allergy, foreign body, parasites, conformation, endocrine disease, otitis media or another primary/perpetuating cause rather than repeatedly suppressing secondary infection.
  • Marbofloxacin is an EMA AMEG Category B fluoroquinolone. Do not use this combination prophylactically or as a routine first choice; use a lower-category topical option when likely effective and document why a fluoroquinolone is required. Culture and susceptibility are especially important with rods, chronic/recurrent disease or poor response.
  • Do not use when resistance to marbofloxacin or clotrimazole is known, or with hypersensitivity to fluoroquinolones, azole antifungals, corticosteroids or excipients. Failure despite correct administration requires diagnosis and susceptibility review, not automatic repetition or prolongation.
  • Avoid use in young growing dogs unless the exceptional need clearly outweighs the risk. Quinolones are associated with weight-bearing cartilage injury and arthropathy in immature animals.
  • Do not use during pregnancy or lactation. Record reproductive status before treatment and choose a suitable alternative for pregnant, breeding or nursing animals.
  • Clean and dry the external canal before dosing, shake the suspension as directed, instil exactly ten drops once daily and massage the ear base gently. Reassess at day 7 before extending to 14 days; use a separate cannula/dropper for each dog and do not continue beyond the labelled course.
  • Rare, usually transient deafness is reported, mainly in older dogs. Establish baseline hearing and neurologic status when relevant; stop and reassess promptly for reduced hearing, pain, marked erythema, vestibular signs or worsening discharge.
  • Prolonged or intensive topical corticosteroid exposure can cause skin thinning, delayed healing, biochemical/haematological changes and adrenal suppression. Avoid duplicate otic/systemic corticosteroids without review and investigate persistent inflammation rather than extending treatment.
  • Avoid skin and eye contact, wash hands after administration and keep the applicator uncontaminated. People hypersensitive to fluoroquinolones, azole antifungals or corticosteroids should avoid handling; seek medical advice after accidental ingestion or persistent exposure symptoms.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Marbofloxacin3 mg/ml Clotrimazole10 mg/ml Dexamethasone0.9 mg/ml
Formulation Type
Ear drops
Administration route
Into the ear
Manufacturer
Vetoquinol · France
Registration
Georgia No
EU Yes, veterinary
Verified on: 15 Oct 2026
UK Yes, veterinary
Verified on: 15 Oct 2026
US No
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Complete labelled dog/cat ophthalmic role: bacterial, chemical or traumatic conjunctival, eyelid, corneal, uveal, injury-related and perioperative disease, including ulcer/erosion claims, with modern corneal-safety boundaries
3.2/10
Poor / unconvincing
vetman assessment

Ciflodex

4.5/1 mg/ml eye and ear drops suspension, 10 ml for dogs and cats
Assessed clinical scopeDog · Complete labelled dog/cat ophthalmic role: bacterial, chemical or traumatic conjunctival, eyelid, corneal, uveal, injury-related and perioperative disease, including ulcer/erosion claims, with modern corneal-safety boundaries · Into the eye
Care settingVeterinarian-directed treatment only after complete ocular examination, fluorescein staining, infection assessment and IOP review where indicated, with early scheduled recheck
vetman score 3.2/10 Poor / unconvincing
Evidence confidence: Low Georgia: Yes, veterinary · № 000208 · Verified on 23 Oct 2026

A registered but poorly supported fixed eye combination whose broad label includes the very corneal ulcers/erosions that make topical dexamethasone dangerous. Ciprofloxacin may fit selected susceptible infections, but without an intact fluorescein-negative cornea, a diagnosis supporting both components and close recheck, this is a poor option rather than a general red-eye treatment.

Regulatory and scientific credibility4.5/10

Exact 10 ml identity, strengths, dog/cat routes, dose schedules and Georgian authorisation 000208 are current and traceable. However clinical detail is available only on a manufacturer sales page, no internationally recognised exact veterinary authorisation or assessment dossier was found, and the page's broad ulcer/trauma claims conflict with established ophthalmic corticosteroid safety.

Clinical efficacy3.0/10

Ciprofloxacin can cover selected susceptible ocular bacteria and dexamethasone can suppress steroid-responsive inflammation, but no exact-product outcome study supports this broad mixed-cause label. The fixed steroid is inappropriate for many infected/ulcerated eyes, and a direct canine in-vitro study found dexamethasone significantly increased ciprofloxacin resistance/MIC in S. pseudintermedius and P. aeruginosa isolates.

Safety and tolerability2.0/10

The exact page explicitly lists corneal ulcers/erosions despite dexamethasone delaying epithelial repair, promoting collagenolysis/melting and masking infection. It also acknowledges irritation, allergy, secondary glaucoma and steroid cataract; systemic absorption, pressure effects and steroid keratopathy are independently documented, while exact target-eye safety margins are absent.

Clinical practicality3.5/10

Ready-to-use drops and a 5-10-day course are familiar, but 2-4 daily doses—and every 2-3 hours in severe cases—create substantial home/clinic burden. Safe use also requires shaking, atraumatic restraint, fluorescein and infection assessment, tip hygiene, spacing other drops, early recheck and one-month open-bottle control.

Full-course cost-effectiveness-

Current Georgian price for the exact 10 ml bottle and complete route-specific course was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete eye-label boundary: conjunctivitis, blepharitis, keratitis/keratoconjunctivitis, iritis/iridocyclitis, ulcer/erosion, trauma/foreign body/chemical and perioperative disease are listed. This does not make one fixed antibiotic-steroid appropriate for every cause; diagnose the compartment, epithelial integrity and microbial/inflammatory role first.
  • Shake and give 1-2 conjunctival drops 2-4 times daily for 5-10 days; severe cases may receive 1-2 drops every 2-3 hours only for the first 1-2 days. Heavy discharge: use the label's cleaning step, then administer the treatment dose. Reassess early rather than extending blindly.
  • Hard stop: perform fluorescein staining before the first dose and at any new pain or deterioration. Despite the exact label listing corneal ulcer/erosion, do not use topical dexamethasone over an epithelial defect, thinning, melting, descemetocele, perforation or unhealed penetrating injury.
  • Use ciprofloxacin only when a susceptible bacterial role is clinically justified; culture/susceptibility is important in ulcerative keratitis, deep infection, rods, recurrence, prior fluoroquinolone exposure or poor response. Dexamethasone can alter susceptibility and suppress visible inflammation without microbial cure.
  • Do not use for viral or fungal eye/ear disease or uncontrolled infection. Steroid-driven reduction in redness, pain or discharge does not establish eradication and can permit microbial overgrowth; stop and re-evaluate if response is incomplete or deterioration occurs.
  • Monitor for irritation, itching, tearing, allergy, delayed healing, infection, IOP rise, secondary glaucoma, steroid cataract and corneal opacity/keratopathy. New blepharospasm, clouding, staining, vision change or worsening discharge requires immediate cessation and examination.
  • The exact page prohibits concurrent NSAIDs, theophylline, amphotericin and literally “other calcium-depleting medicines,” and prohibits use during vaccination. No exact interaction study explains the calcium wording; document all systemic/topical medicines and seek source clarification rather than silently changing or ignoring it.
  • Use cautiously below 7 days of age and in pregnancy. The exact instruction does not establish lactation, breeding, liver/kidney disease, repeated-course or overdose safety; use the shortest justified course and a patient-specific benefit-risk decision.
  • Shake thoroughly, wash hands, use atraumatic restraint and keep the dropper tip sterile and away from eye, lashes, skin and fingers. Separate other eye medicines so one does not wash out another; ointment is generally placed last unless the ophthalmologist directs otherwise.
  • Store dry and dark at 10-25 C out of children's reach and discard one month after opening. Record opening date, route/eye/ear, dose, diagnosis, culture/cytology basis and recheck; never use one contaminated bottle interchangeably between eyes and ears.
Assessment sources
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Dog Complete labelled dog/cat otic role: acute or chronic bacterial, chemical or traumatic external-ear inflammation, otitis and otorrhoea, including after intervention, only with an intact tympanum
4.2/10
Weak evidence support
vetman assessment

Ciflodex

4.5/1 mg/ml eye and ear drops suspension, 10 ml for dogs and cats
Assessed clinical scopeDog · Complete labelled dog/cat otic role: acute or chronic bacterial, chemical or traumatic external-ear inflammation, otitis and otorrhoea, including after intervention, only with an intact tympanum · Into the ear
Care settingVeterinarian-directed external-ear treatment after otoscopy, intact-tympanum confirmation and cytology before cleaning, with cause-directed care and clinical/cytologic recheck
vetman score 4.2/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 000208 · Verified on 23 Oct 2026

A weak, selective dog otic option when cytology supports susceptible bacterial external otitis and the tympanum is intact. Plausible ingredients and a short course cannot replace the missing exact outcome/safety programme, antifungal gap, organism criteria or size bands.

Regulatory and scientific credibility4.5/10

Exact 10 ml identity, strengths, dog/cat routes, dose schedules and Georgian authorisation 000208 are current and traceable. However clinical detail is available only on a manufacturer sales page, no internationally recognised exact veterinary authorisation or assessment dossier was found, and the page's broad ulcer/trauma claims conflict with established ophthalmic corticosteroid safety.

Clinical efficacy4.0/10

Ciprofloxacin/dexamethasone has a credible otic formulation bridge and can plausibly help susceptible bacterial inflammatory otitis externa, but no exact dog outcome study, organism eligibility or numeric size bands were found. It lacks an antifungal, so it cannot cover the common mixed Malassezia role of authorised veterinary combinations or justify treatment of every chemically/traumatically inflamed ear.

Safety and tolerability4.0/10

Topical exposure is likely lower-risk than systemic fluoroquinolone/steroid use, and a human same-class otic comparator has controlled non-intact-ear data. But that human formulation cannot validate this veterinary suspension: the exact label omits tympanum status, otitis media/interna, auditory/vestibular outcomes, adverse-event frequencies and repeat-course safety.

Clinical practicality4.5/10

A 5-10-day ready-drop course is workable, but 2-3 daily administrations, cleaning, massage and complete restraint still matter. The 1-4-drop range lacks weight/size bands, and otoscopy, cytology, intact-tympanum confirmation and recheck add justified clinical work.

Full-course cost-effectiveness-

Current Georgian price for the exact 10 ml bottle and complete route-specific course was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete ear-label boundary: acute/chronic bacterial, chemical or traumatic inflammation, otitis and otorrhoea are listed. This score covers only diagnosed external-ear disease with an intact tympanum, not otitis media/interna, undifferentiated discharge or every inflamed ear.
  • Shake and give 1-4 drops by patient size 2-3 times daily for 5-10 days after indicated cleaning; the exact label provides no size/weight bands. Document the selected volume, canal findings and response instead of treating 1-4 drops as interchangeable.
  • Hard stop: perform otoscopy and confirm an intact tympanic membrane before use. The exact label gives no perforation or middle-ear safety data; do not transfer human CIPRODEX tympanostomy evidence to this veterinary formulation or use in an unvisualised/non-intact ear.
  • Obtain cytology before cleaning in every otitis case; culture/susceptibility is important with rods, chronic/recurrent disease, prior fluoroquinolone exposure or poor response. It has no antifungal, so yeast or mixed infection needs a different cause-directed plan.
  • Do not use for viral or fungal eye/ear disease or uncontrolled infection. Steroid-driven reduction in redness, pain or discharge does not establish eradication and can permit microbial overgrowth; stop and re-evaluate if response is incomplete or deterioration occurs.
  • Stop for marked irritation, swelling, worsening discharge/pain, head tilt, nystagmus, ataxia, facial/Horner signs or hearing change. Investigate contact reaction, resistant infection, foreign body, mass/polyp and middle/inner-ear disease rather than layering more drops.
  • The exact page prohibits concurrent NSAIDs, theophylline, amphotericin and literally “other calcium-depleting medicines,” and prohibits use during vaccination. No exact interaction study explains the calcium wording; document all systemic/topical medicines and seek source clarification rather than silently changing or ignoring it.
  • Use cautiously below 7 days of age and in pregnancy. The exact instruction does not establish lactation, breeding, liver/kidney disease, repeated-course or overdose safety; use the shortest justified course and a patient-specific benefit-risk decision.
  • Shake thoroughly, clean as directed, use safe restraint and prevent tip contact with canal, pinna, skin or fingers. Massage only when comfortable and the tympanum is intact; prevent licking and cross-use between infected ears/animals.
  • Store dry and dark at 10-25 C out of children's reach and discard one month after opening. Record opening date, route/eye/ear, dose, diagnosis, culture/cytology basis and recheck; never use one contaminated bottle interchangeably between eyes and ears.
Assessment sources
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Complete labelled dog/cat ophthalmic role: bacterial, chemical or traumatic conjunctival, eyelid, corneal, uveal, injury-related and perioperative disease, including ulcer/erosion claims, with modern corneal-safety boundaries
2.9/10
Poor / unconvincing
vetman assessment

Ciflodex

4.5/1 mg/ml eye and ear drops suspension, 10 ml for dogs and cats
Assessed clinical scopeCat · Complete labelled dog/cat ophthalmic role: bacterial, chemical or traumatic conjunctival, eyelid, corneal, uveal, injury-related and perioperative disease, including ulcer/erosion claims, with modern corneal-safety boundaries · Into the eye
Care settingVeterinarian-directed treatment only after complete ocular examination, fluorescein staining, infection assessment and IOP review where indicated, with early scheduled recheck
vetman score 2.9/10 Poor / unconvincing
Evidence confidence: Low Georgia: Yes, veterinary · № 000208 · Verified on 23 Oct 2026

A poor feline eye option: exact efficacy is absent, common FHV-associated disease can be worsened by steroid exposure, and the label's ulcer claim conflicts with a hard corneal-safety boundary. It should never be used empirically for a red or painful cat eye.

Regulatory and scientific credibility4.5/10

Exact 10 ml identity, strengths, dog/cat routes, dose schedules and Georgian authorisation 000208 are current and traceable. However clinical detail is available only on a manufacturer sales page, no internationally recognised exact veterinary authorisation or assessment dossier was found, and the page's broad ulcer/trauma claims conflict with established ophthalmic corticosteroid safety.

Clinical efficacy2.5/10

No exact-product feline outcome study was found. Ciprofloxacin activity and dexamethasone anti-inflammatory action are plausible only after diagnosis, while viral disease—especially FHV-associated conjunctivitis/keratitis—is common and specifically makes the fixed steroid problematic; canine in-vitro findings and human combinations are indirect, not feline efficacy.

Safety and tolerability1.5/10

All corneal healing, infection, glaucoma and cataract hazards apply, plus topical corticosteroids can reactivate feline herpesvirus and precipitate ulcerative keratitis or sequestrum. An exact label that simultaneously excludes viral disease yet broadly includes ulcers without requiring fluorescein testing creates a particularly poor feline safety fit; controlled exact feline safety is absent.

Clinical practicality3.5/10

Ready-to-use drops and a 5-10-day course are familiar, but 2-4 daily doses—and every 2-3 hours in severe cases—create substantial home/clinic burden. Safe use also requires shaking, atraumatic restraint, fluorescein and infection assessment, tip hygiene, spacing other drops, early recheck and one-month open-bottle control.

Full-course cost-effectiveness-

Current Georgian price for the exact 10 ml bottle and complete route-specific course was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete eye-label boundary: conjunctivitis, blepharitis, keratitis/keratoconjunctivitis, iritis/iridocyclitis, ulcer/erosion, trauma/foreign body/chemical and perioperative disease are listed. This does not make one fixed antibiotic-steroid appropriate for every cause; diagnose the compartment, epithelial integrity and microbial/inflammatory role first.
  • Shake and give 1-2 conjunctival drops 2-4 times daily for 5-10 days; severe cases may receive 1-2 drops every 2-3 hours only for the first 1-2 days. Heavy discharge: use the label's cleaning step, then administer the treatment dose. Reassess early rather than extending blindly.
  • Hard stop: perform fluorescein staining before the first dose and at any new pain or deterioration. Despite the exact label listing corneal ulcer/erosion, do not use topical dexamethasone over an epithelial defect, thinning, melting, descemetocele, perforation or unhealed penetrating injury.
  • Use ciprofloxacin only when a susceptible bacterial role is clinically justified; culture/susceptibility is important in ulcerative keratitis, deep infection, rods, recurrence, prior fluoroquinolone exposure or poor response. Dexamethasone can alter susceptibility and suppress visible inflammation without microbial cure.
  • Do not use for suspected FHV-1 or other viral/fungal ocular disease. Topical corticosteroids can reactivate feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum; investigate dendritic/geographic lesions and treat the cause before any further immunosuppression.
  • Monitor for irritation, itching, tearing, allergy, delayed healing, infection, IOP rise, secondary glaucoma, steroid cataract and corneal opacity/keratopathy. New blepharospasm, clouding, staining, vision change or worsening discharge requires immediate cessation and examination.
  • The exact page prohibits concurrent NSAIDs, theophylline, amphotericin and literally “other calcium-depleting medicines,” and prohibits use during vaccination. No exact interaction study explains the calcium wording; document all systemic/topical medicines and seek source clarification rather than silently changing or ignoring it.
  • Use cautiously below 7 days of age and in pregnancy. The exact instruction does not establish lactation, breeding, liver/kidney disease, repeated-course or overdose safety; use the shortest justified course and a patient-specific benefit-risk decision.
  • Shake thoroughly, wash hands, use atraumatic restraint and keep the dropper tip sterile and away from eye, lashes, skin and fingers. Separate other eye medicines so one does not wash out another; ointment is generally placed last unless the ophthalmologist directs otherwise.
  • Store dry and dark at 10-25 C out of children's reach and discard one month after opening. Record opening date, route/eye/ear, dose, diagnosis, culture/cytology basis and recheck; never use one contaminated bottle interchangeably between eyes and ears.
Assessment sources
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Complete labelled dog/cat otic role: acute or chronic bacterial, chemical or traumatic external-ear inflammation, otitis and otorrhoea, including after intervention, only with an intact tympanum
4.0/10
Weak evidence support
vetman assessment

Ciflodex

4.5/1 mg/ml eye and ear drops suspension, 10 ml for dogs and cats
Assessed clinical scopeCat · Complete labelled dog/cat otic role: acute or chronic bacterial, chemical or traumatic external-ear inflammation, otitis and otorrhoea, including after intervention, only with an intact tympanum · Into the ear
Care settingVeterinarian-directed external-ear treatment after otoscopy, intact-tympanum confirmation and cytology before cleaning, with cause-directed care and clinical/cytologic recheck
vetman score 4.0/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 000208 · Verified on 23 Oct 2026

A weak feline otic option with plausible local activity but no exact feline outcomes, antifungal coverage, tympanic safety programme or objective drop bands. Use only after diagnosis, intact-tympanum confirmation and planned recheck—not for every inflamed or discharging ear.

Regulatory and scientific credibility4.5/10

Exact 10 ml identity, strengths, dog/cat routes, dose schedules and Georgian authorisation 000208 are current and traceable. However clinical detail is available only on a manufacturer sales page, no internationally recognised exact veterinary authorisation or assessment dossier was found, and the page's broad ulcer/trauma claims conflict with established ophthalmic corticosteroid safety.

Clinical efficacy3.5/10

The same antibacterial/anti-inflammatory rationale is plausible, but no exact feline outcome or target-organism study was found and direct feline otitis evidence is sparse. The broad otitis/otorrhoea label supplies neither cytology criteria nor antifungal activity, so dog, human and other veterinary combinations provide only indirect support.

Safety and tolerability4.0/10

The main local and tympanic uncertainties apply, while no exact feline canal, hearing or vestibular safety study was found. Cats can be difficult to examine and restrain, and an unrecognised polyp/middle-ear process or contact reaction can be masked by steroid relief; exact adverse-event denominators and repeat-course data are absent.

Clinical practicality4.0/10

The small ready-drop volume is feasible, but many cats resist repeated ear handling 2-3 times daily for 5-10 days. The unbanded 1-4-drop range, safe restraint, cleaning, otoscopy/cytology, intact-tympanum confirmation, tip hygiene and recheck create a meaningful welfare/adherence burden.

Full-course cost-effectiveness-

Current Georgian price for the exact 10 ml bottle and complete route-specific course was unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete ear-label boundary: acute/chronic bacterial, chemical or traumatic inflammation, otitis and otorrhoea are listed. This score covers only diagnosed external-ear disease with an intact tympanum, not otitis media/interna, undifferentiated discharge or every inflamed ear.
  • Shake and give 1-4 drops by patient size 2-3 times daily for 5-10 days after indicated cleaning; the exact label provides no size/weight bands. Document the selected volume, canal findings and response instead of treating 1-4 drops as interchangeable.
  • Hard stop: perform otoscopy and confirm an intact tympanic membrane before use. The exact label gives no perforation or middle-ear safety data; do not transfer human CIPRODEX tympanostomy evidence to this veterinary formulation or use in an unvisualised/non-intact ear.
  • Obtain cytology before cleaning in every otitis case; culture/susceptibility is important with rods, chronic/recurrent disease, prior fluoroquinolone exposure or poor response. It has no antifungal, so yeast or mixed infection needs a different cause-directed plan.
  • Do not use for viral or fungal eye/ear disease or uncontrolled infection. Steroid-driven reduction in redness, pain or discharge does not establish eradication and can permit microbial overgrowth; stop and re-evaluate if response is incomplete or deterioration occurs.
  • Stop for marked irritation, swelling, worsening discharge/pain, head tilt, nystagmus, ataxia, facial/Horner signs or hearing change. Investigate contact reaction, resistant infection, foreign body, mass/polyp and middle/inner-ear disease rather than layering more drops.
  • The exact page prohibits concurrent NSAIDs, theophylline, amphotericin and literally “other calcium-depleting medicines,” and prohibits use during vaccination. No exact interaction study explains the calcium wording; document all systemic/topical medicines and seek source clarification rather than silently changing or ignoring it.
  • Use cautiously below 7 days of age and in pregnancy. The exact instruction does not establish lactation, breeding, liver/kidney disease, repeated-course or overdose safety; use the shortest justified course and a patient-specific benefit-risk decision.
  • Shake thoroughly, clean as directed, use safe restraint and prevent tip contact with canal, pinna, skin or fingers. Massage only when comfortable and the tympanum is intact; prevent licking and cross-use between infected ears/animals.
  • Store dry and dark at 10-25 C out of children's reach and discard one month after opening. Record opening date, route/eye/ear, dose, diagnosis, culture/cytology basis and recheck; never use one contaminated bottle interchangeably between eyes and ears.
Assessment sources
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Ciprofloxacin4.5 mg/ml Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye, Into the ear
Manufacturer
Brovapharma LLC · Ukraine
Manufacturer (register)
Brovapharma Ltd, Ukraine
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 746, 19 Oct 2026.
Registration
Georgia Yes, veterinary
In force until 06 Oct 2027
Veterinary (National Food Agency)
In the register: ციფლოდექსი — თვალისა და ყურის წვეთები
№ 000208
Verified on: 23 Oct 2026
EU No
UK No
US No
Verified on: 23 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified Shake before every use. Eye: 1-2 drops into the conjunctival sac 2-4 times daily for 5-10 days; in severe cases every 2-3 hours only during the first 1-2 days, with prompt examination and reassessment. Ear: after otoscopy, cytology and appropriate cleaning, 1-4 drops according to patient size 2-3 times daily for 5-10 days; the label supplies no size bands. For heavy discharge the label uses 3-4 drops for cleaning with sterile gauze, followed by 1-2 treatment drops. Avoid dropper contact and discard one month after opening.

Dekort 0.5 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.1/10
Situational / acceptable
vetman assessment

Dekort

0.5 mg, tablet, human medicine
Assessed clinical scopeDog · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, human · № რ-044863 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility6.0/10

This exact human 0.5 mg tablet has a sourced current Georgian registration and an exact official manufacturer instruction. Exhaustive current checks record no exact EU/EEA, GB or US registration, and no regulator-hosted complete exact-product dossier was located; veterinary use is off-label.

Clinical efficacy7.5/10

Dexamethasone is a potent, well-absorbed, long-acting oral glucocorticoid, and a current authorised veterinary 0.5 mg product directly supports symptomatic or adjunct treatment of inflammatory and allergic disease in dogs. It can provide strong short-term control when the diagnosis and dose target are correct, but does not cure the underlying disease and is usually less suitable than a shorter-acting steroid for adjustable chronic therapy.

Safety and tolerability5.0/10

Short, appropriately selected courses can be manageable, but cortisol suppression is very common with the authorised veterinary comparator and long-acting dexamethasone can cause infection, gastrointestinal ulceration, metabolic effects, delayed healing and HPA-axis suppression. Long-term oral use is specifically discouraged when a shorter-acting alternative such as prednisolone can provide control.

Clinical practicality6.0/10

A 0.5 mg whole-tablet unit is compact and simple to store and can fit some small-to-medium canine doses, but this human tablet is not the flavoured, quarterable veterinary comparator. The exact instruction does not establish fractional veterinary dosing, so smaller increments or many-tablet regimens require a more suitable strength or validated compound.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.2/10
Situational / acceptable
vetman assessment

Dekort

0.5 mg, tablet, human medicine
Assessed clinical scopeCat · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, human · № რ-044863 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility6.0/10

This exact human 0.5 mg tablet has a sourced current Georgian registration and an exact official manufacturer instruction. Exhaustive current checks record no exact EU/EEA, GB or US registration, and no regulator-hosted complete exact-product dossier was located; veterinary use is off-label.

Clinical efficacy7.5/10

A current authorised veterinary 0.5 mg product directly supports oral dexamethasone for inflammatory and allergic disease in cats, and a small prospective feline study found oral absorption and improvement in hypersensitivity dermatitis. The evidence supports useful short-term control, not every possible immune-mediated claim; response is diagnosis-dependent and treatment must remain adjunctive to cause control.

Safety and tolerability4.5/10

The authorised veterinary label documents very common cortisol suppression and broad glucocorticoid toxicity. In cats, controlled pilot data suggest greater diabetogenic effects than equipotent prednisolone, while prolonged immunosuppressive exposure can produce hyperglycaemia, infection, hepatopathy, skin/muscle change, gastrointestinal injury and adrenal suppression; this narrows the margin for chronic use.

Clinical practicality7.0/10

A 0.5 mg whole-tablet unit often fits clinically relevant feline dosing better than higher human strengths and is simple to store. It is nevertheless an unflavoured human tablet without the veterinary comparator’s validated quarter divisions; cats needing smaller increments, reluctant pill-takers and multi-step tapers may require a more suitable veterinary or compounded form.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Deva Holding · Türkiye
Registration
Georgia Yes, human
In force until 24 Feb 2031
Human (Ministry of Health, RAMA)
In the register: დეკორტი 0.5 მგ, აბი
№ რ-044863
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone-AJIO 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone-AJIO

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-038922 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone-AJIO

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-038922 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Registration
Georgia Yes, human
In force until 24 Aug 2028
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონ-აჯიო 4 მგ/მლ, 1 მლ ამპულა
№ რ-038922
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone-Darnitsa 1 mg/ml (0.1%), Eye drops

eye drops 10 ml, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.8/10
Situational / acceptable
vetman assessment

Dexamethasone-Darnitsa

1 mg/ml (0.1%), eye drops 10 ml, human medicine
Assessed clinical scopeDog · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.8/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045750 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy8.0/10

Topical 0.1% dexamethasone is a standard, cornea-penetrating veterinary corticosteroid for noninfectious anterior ocular inflammation. Current canine data support improvement in moderate-to-severe follicular conjunctivitis and combination therapy for chronic superficial keratitis, while established use covers anterior uveitis, immune-mediated keratitis and episcleritis; diagnosis and cause-directed therapy determine benefit.

Safety and tolerability6.0/10

Correctly selected use is usually locally tolerable, but corticosteroids delay epithelial healing, increase collagenase activity and can convert an occult abrasion into a melting ulcer. Repeated treatment can increase intraocular pressure, promote infection, cataract and steroid keratopathy, and systemic absorption with cortisol suppression is documented after four-times-daily dosing.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Reassess the diagnosis urgently if blepharospasm, discharge, corneal clouding, focal staining, vision change or worsening redness appears; stop dexamethasone until ulceration and infection have been excluded.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.2/10
Situational / acceptable
vetman assessment

Dexamethasone-Darnitsa

1 mg/ml (0.1%), eye drops 10 ml, human medicine
Assessed clinical scopeCat · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045750 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy7.0/10

Topical 0.1% dexamethasone is an established cornea-penetrating corticosteroid for selected noninfectious feline anterior ocular inflammation, including immune-mediated keratitis, conjunctival disease and anterior uveitis. Direct controlled feline efficacy data are limited, and latent FHV-1 or infectious disease can make an apparently inflammatory presentation steroid-inappropriate.

Safety and tolerability5.0/10

Corneal ulceration or untreated infection creates a serious local hazard, and feline herpesvirus may reactivate with topical steroid exposure, causing ulceration or sequestrum. Longer treatment can increase intraocular pressure, delay healing, promote infection or cataract and cause systemic glucocorticoid exposure; feline product-specific safety data are limited.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Topical corticosteroids can reactivate latent feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum. In a cat with compatible history or dendritic/geographic disease, stop steroid treatment and investigate/treat FHV-associated disease before considering further immunosuppression.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Darnitsa · Ukraine
Registration
Georgia Yes, human
In force until 23 Jun 2031
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი-დარნიცა 1 მგ/მლ (0.1%), თვალის წვეთები 10 მლ
№ რ-045750
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone-Darnitsa 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone-Darnitsa

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046182, რ-034187 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone-Darnitsa

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046182, რ-034187 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Darnitsa · Ukraine
Registration
Georgia Yes, human
In force until 20 Aug 2031
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი-დარნიცა 4 მგ/მლ, 1 მლ ამპულა
№ რ-046182, რ-034187
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone Bene Pharm 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.3/10
Situational / acceptable
vetman assessment

Dexamethasone Bene Pharm

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.3/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043263 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility6.5/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia and EU/EEA, with transparent strength, route and manufacturer, but no current GB or US registration. Animal use is off-label and exact-product veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.3/10
Situational / acceptable
vetman assessment

Dexamethasone Bene Pharm

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.3/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043263 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility6.5/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia and EU/EEA, with transparent strength, route and manufacturer, but no current GB or US registration. Animal use is off-label and exact-product veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Rompharm · Romania
Registration
Georgia Yes, human
In force until 15 May 2030
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი ბენე ფარმი 4 მგ/მლ, 1 მლ ამპულა
№ რ-043263
Verified on: 16 Oct 2026
EU Yes, human
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.8/10
Situational / acceptable
vetman assessment

Dexamethasone Dentafill Plus

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeDog · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.8/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035100 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy8.0/10

Topical 0.1% dexamethasone is a standard, cornea-penetrating veterinary corticosteroid for noninfectious anterior ocular inflammation. Current canine data support improvement in moderate-to-severe follicular conjunctivitis and combination therapy for chronic superficial keratitis, while established use covers anterior uveitis, immune-mediated keratitis and episcleritis; diagnosis and cause-directed therapy determine benefit.

Safety and tolerability6.0/10

Correctly selected use is usually locally tolerable, but corticosteroids delay epithelial healing, increase collagenase activity and can convert an occult abrasion into a melting ulcer. Repeated treatment can increase intraocular pressure, promote infection, cataract and steroid keratopathy, and systemic absorption with cortisol suppression is documented after four-times-daily dosing.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Reassess the diagnosis urgently if blepharospasm, discharge, corneal clouding, focal staining, vision change or worsening redness appears; stop dexamethasone until ulceration and infection have been excluded.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.2/10
Situational / acceptable
vetman assessment

Dexamethasone Dentafill Plus

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeCat · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035100 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy7.0/10

Topical 0.1% dexamethasone is an established cornea-penetrating corticosteroid for selected noninfectious feline anterior ocular inflammation, including immune-mediated keratitis, conjunctival disease and anterior uveitis. Direct controlled feline efficacy data are limited, and latent FHV-1 or infectious disease can make an apparently inflammatory presentation steroid-inappropriate.

Safety and tolerability5.0/10

Corneal ulceration or untreated infection creates a serious local hazard, and feline herpesvirus may reactivate with topical steroid exposure, causing ulceration or sequestrum. Longer treatment can increase intraocular pressure, delay healing, promote infection or cataract and cause systemic glucocorticoid exposure; feline product-specific safety data are limited.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Topical corticosteroids can reactivate latent feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum. In a cat with compatible history or dendritic/geographic disease, stop steroid treatment and investigate/treat FHV-associated disease before considering further immunosuppression.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Dentafill Plus · Uzbekistan
Registration
Georgia Yes, human
In force until 28 Apr 2027
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი დენტაფილ პლუსი 1 მგ/მლ (0.1%), თვალის წვეთები 5 მლ
№ რ-035100
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone Kalceks 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Kalceks

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035107 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Kalceks

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-035107 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Kalceks · Latvia
Registration
Georgia Yes, human
In force until 11 Nov 2026
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კალცექსი 4 მგ/მლ, 1 მლ ამპულა
№ რ-035107
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL470150029
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone Krka 0.5 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.7/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

0.5 mg, tablet, human medicine
Assessed clinical scopeDog · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042830 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 0.5 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, an identifiable current UK SmPC and no exact US registration in the checked register. Veterinary use remains off-label, although an authorised veterinary 0.5 mg oral comparator directly supports species, route and strength.

Clinical efficacy7.5/10

Dexamethasone is a potent, well-absorbed, long-acting oral glucocorticoid, and a current authorised veterinary 0.5 mg product directly supports symptomatic or adjunct treatment of inflammatory and allergic disease in dogs. It can provide strong short-term control when the diagnosis and dose target are correct, but does not cure the underlying disease and is usually less suitable than a shorter-acting steroid for adjustable chronic therapy.

Safety and tolerability5.0/10

Short, appropriately selected courses can be manageable, but cortisol suppression is very common with the authorised veterinary comparator and long-acting dexamethasone can cause infection, gastrointestinal ulceration, metabolic effects, delayed healing and HPA-axis suppression. Long-term oral use is specifically discouraged when a shorter-acting alternative such as prednisolone can provide control.

Clinical practicality6.0/10

A 0.5 mg whole-tablet unit is compact and simple to store and can fit some small-to-medium canine doses, but this human tablet is not the flavoured, quarterable veterinary comparator. The exact instruction does not establish fractional veterinary dosing, so smaller increments or many-tablet regimens require a more suitable strength or validated compound.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.7/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

0.5 mg, tablet, human medicine
Assessed clinical scopeCat · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042830 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 0.5 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, an identifiable current UK SmPC and no exact US registration in the checked register. Veterinary use remains off-label, although an authorised veterinary 0.5 mg oral comparator directly supports species, route and strength.

Clinical efficacy7.5/10

A current authorised veterinary 0.5 mg product directly supports oral dexamethasone for inflammatory and allergic disease in cats, and a small prospective feline study found oral absorption and improvement in hypersensitivity dermatitis. The evidence supports useful short-term control, not every possible immune-mediated claim; response is diagnosis-dependent and treatment must remain adjunctive to cause control.

Safety and tolerability4.5/10

The authorised veterinary label documents very common cortisol suppression and broad glucocorticoid toxicity. In cats, controlled pilot data suggest greater diabetogenic effects than equipotent prednisolone, while prolonged immunosuppressive exposure can produce hyperglycaemia, infection, hepatopathy, skin/muscle change, gastrointestinal injury and adrenal suppression; this narrows the margin for chronic use.

Clinical practicality7.0/10

A 0.5 mg whole-tablet unit often fits clinically relevant feline dosing better than higher human strengths and is simple to store. It is nevertheless an unflavoured human tablet without the veterinary comparator’s validated quarter divisions; cats needing smaller increments, reluctant pill-takers and multi-step tapers may require a more suitable veterinary or compounded form.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Krka · Slovenia
Registration
Georgia Yes, human
In force until 25 Feb 2030
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 0.5 მგ, აბი
№ რ-042830
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL001421313, PL016560205, PL016560206, PL016560207
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexamethasone Krka 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045250 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.5/10
Situational / acceptable
vetman assessment

Dexamethasone Krka

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045250 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility7.0/10

The exact 4 mg/ml human ampoule has sourced current registrations in Georgia, EU/EEA and GB, with transparent strength, route and manufacturer. Animal use remains off-label; applicable veterinary labels and guidelines support the ingredient and class rather than this exact human presentation.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Krka · Slovenia
Registration
Georgia Yes, human
In force until 16 Apr 2031
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი კრკა 4 მგ/მლ, 1 მლ ამპულა
№ რ-045250
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL001421313, PL016560205, PL016560206, PL016560207
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Phosphate Eletis

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043496 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Phosphate Eletis

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043496 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Registration
Georgia Yes, human
In force until 04 May 2029
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონის ფოსფატი ელეტისი 4 მგ/მლ, 1 მლ ამპულა
№ რ-043496
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Phosphate Vinh Phuc

4 mg/ml (0.4%), 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037103 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Phosphate Vinh Phuc

4 mg/ml (0.4%), 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037103 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Vinh Phuc · Vietnam
Registration
Georgia Yes, human
In force until 30 Dec 2027
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონის ფოსფატი ვინ ფუკი 4 მგ/მლ (0.4%), 1 მლ ამპულა
№ რ-037103
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Uzgermed

4 mg/ml (0.4%), 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037874 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexamethasone Uzgermed

4 mg/ml (0.4%), 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037874 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Uzgermed Pharm · Uzbekistan
Registration
Georgia Yes, human
In force until 13 Apr 2028
Human (Ministry of Health, RAMA)
In the register: დექსამეტაზონი უზგერმედი 4 მგ/მლ (0.4%), 1 მლ ამპულა
№ რ-037874
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexapex 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexapex

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042196 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexapex

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-042196 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Ciron Drugs · India
Registration
Georgia Yes, human
In force until 10 Oct 2029
Human (Ministry of Health, RAMA)
In the register: დექსაპექსი 4 მგ/მლ, 1 მლ ამპულა
№ რ-042196
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Dexzi 4 mg/ml, Solution

1 ml ampoule, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexzi

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeDog · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037918 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care
6.1/10
Situational / acceptable
vetman assessment

Dexzi

4 mg/ml, 1 ml ampoule, human medicine
Assessed clinical scopeCat · Parenteral dexamethasone for a diagnosed acute or severe inflammatory, allergic or immune-mediated condition when systemic glucocorticoid treatment is justified and oral therapy is unsuitable; not routine uncomplicated allergy or anaphylaxis care · IV,IM
Care settingVeterinary clinic or hospital use after diagnosis and contraindication review, with exact small-volume measurement, route-specific administration, infection management and clinical/metabolic monitoring
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-037918 · Verified on 16 Oct 2026 Off-label use

A useful, precisely measurable clinic formulation when a diagnosed condition genuinely warrants parenteral dexamethasone and oral treatment is unsuitable. Its value is diagnosis-dependent, veterinary use of the exact human ampoule is off-label, and routine use for uncomplicated allergy or anaphylaxis is not supported; screen contraindications and avoid NSAID overlap.

Regulatory and scientific credibility5.5/10

The exact 4 mg/ml human ampoule has a sourced current Georgian registration and identifiable strength, route and manufacturer, but no current exact EU/EEA, GB or US registration was found. Animal use is off-label and formulation-specific veterinary evidence is absent.

Clinical efficacy6.0/10

Dexamethasone is a potent, established veterinary anti-inflammatory glucocorticoid and short systemic courses can be useful for selected severe inflammatory or immune-mediated disease. Benefit varies sharply by diagnosis: current RECOVER guidance recommends against routine glucocorticoids for uncomplicated allergy and anaphylaxis, and evidence does not validate every broad historical use or this exact human ampoule.

Safety and tolerability5.5/10

A single selected dose is usually tolerated, but dexamethasone is long acting and highly potent. It can worsen infection, hyperglycaemia, gastrointestinal ulceration, fluid/electrolyte disturbance, delayed healing and HPA suppression; pregnancy, diabetes, hyperadrenocorticism and major cardiac, renal, ocular or ulcer disease materially change the benefit-risk.

Clinical practicality8.0/10

The sterile 4 mg/ml, 1 ml ampoule supports rapid IV or IM clinic administration and avoids a prolonged home regimen. At the veterinary 0.1 mg/kg comparator dose it requires only 0.025 ml/kg, so very small patients need a precise low-dead-space syringe; verify the exact insert, excipients, compatibility and single-use handling.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use systemic dexamethasone routinely for uncomplicated allergic reactions or anaphylaxis. Current RECOVER guidance recommends against routine glucocorticoids in both settings; treat anaphylaxis immediately with epinephrine and indicated resuscitation rather than delaying definitive therapy.
  • Avoid concurrent NSAIDs and allow an appropriate washout when switching. The combination materially increases gastrointestinal ulceration, perforation and bleeding risk; review aspirin, meloxicam, carprofen, firocoxib and every other anti-inflammatory exposure.
  • Do not suppress inflammation before excluding or actively treating relevant bacterial, fungal, viral or parasitic infection. Dexamethasone can mask progression, impair host defence and delay wound healing; avoid routine use in systemic infection or viraemia without a compelling, managed indication.
  • Avoid or undertake only an exceptional documented benefit-risk decision in diabetes mellitus, hyperadrenocorticism, gastrointestinal or corneal ulceration, glaucoma, osteoporosis, major cardiac or renal dysfunction and known corticosteroid/excipient hypersensitivity.
  • Do not use routinely during pregnancy: early exposure can cause fetal abnormalities and late exposure can precipitate abortion or premature parturition. Use in growing, lactating, geriatric or debilitated patients only after an individual benefit-risk assessment.
  • Do not combine with a live attenuated vaccine and avoid use around vaccination according to the applicable product information. Immunosuppression can reduce vaccine response; review other immunosuppressants and exposure to infectious disease.
  • Dexamethasone is long acting and suppresses the hypothalamic-pituitary-adrenal axis. Do not use alternate-day dexamethasone as an HPA-sparing strategy; after repeated or prolonged treatment taper rather than stop abruptly, and prefer a shorter-acting corticosteroid when long-term therapy is necessary.
  • Monitor thirst, urination, appetite, vomiting, diarrhoea or melaena, behaviour, body weight, blood pressure, glucose and electrolytes according to dose and duration. Review potassium-depleting diuretics, insulin needs, anticonvulsants and other medicines whose effect can change.
  • This is a 4 mg/ml human 1 ml ampoule, twice the concentration of the 2 mg/ml veterinary comparator. At 0.1 mg/kg, volume is 0.025 ml/kg: use a precise low-dead-space syringe, confirm IV versus IM intent and the exact insert/excipients, do not share a breached single-use ampoule and discard the remainder.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone4 mg/ml
Formulation Type
Solution
Administration route
Intravenous, Intramuscular
Manufacturer
Registration
Georgia Yes, human
In force until 25 Apr 2028
Human (Ministry of Health, RAMA)
In the register: დექსზი 4 მგ/მლ, 1 მლ ამპულა
№ რ-037918
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Marbotis 3 mg/ml + 10 mg/ml + 1 mg/ml, Ear drops

ear drops suspension, for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.5/10
Good
vetman assessment

Marbotis

3 mg/ml + 10 mg/ml + 1 mg/ml, ear drops suspension, for dogs
Assessed clinical scopeDog · Label-concordant treatment of canine otitis externa caused by marbofloxacin-susceptible bacteria and clotrimazole-susceptible fungi, especially Malassezia pachydermatis, with concurrent control of inflammation · Into the ear
Care settingVeterinary diagnosis and selection after otoscopy and cytology; outpatient administration after cleaning and drying, with day-7 veterinary reassessment and investigation of the underlying cause.
vetman score 7.5/10 Good
Evidence confidence: Medium Georgia: No · Verified on 15 Oct 2026

A good authorised generic-hybrid option with regulator-accepted reference equivalence and favourable handling life, but without an independent exact-product outcome trial. Cytology, intact tympanum, antimicrobial stewardship and day-7 reassessment remain essential.

Regulatory and scientific credibility8.5/10

Marbotis has current exact EU/EEA and GB veterinary authorisations, a 2024 regulator-hosted SPC and a public generic-hybrid assessment establishing reference-product equivalence and favourable benefit-risk. It is not registered in the checked Georgian or US registers.

Clinical efficacy7.0/10

The regulator accepted equivalent efficacy claims to Aurizon from matching composition and physicochemical characteristics; the reference combination has comparative canine evidence for bacterial/fungal otitis and Malassezia-associated inflammation. There is no independent exact-product outcome trial, and success still depends on cytology, susceptibility where indicated and control of the underlying cause.

Safety and tolerability7.0/10

Topical exposure is much lower than systemic treatment, but the intact tympanic membrane must be confirmed. Rare mostly transient deafness, local irritation and corticosteroid-related skin thinning, delayed healing, laboratory changes or adrenal suppression are possible; avoid pregnancy/lactation and unnecessary use in growing dogs.

Clinical practicality7.5/10

Ten drops once daily for 7-14 days is manageable and the six-month in-use shelf life limits waste. The ear still requires examination, meticulous cleaning/drying, shaking, dropper filling and massage, and extending beyond day 7 requires veterinary reassessment.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform otoscopy and verify an intact tympanic membrane before every course. Do not use with a perforated or unvisualised tympanum; stop and reassess urgently for head tilt, nystagmus, ataxia, hearing change or other vestibular signs.
  • Cytology is required in every otitis externa case and should be repeated at recheck. Sample before cleaning; identify and manage allergy, foreign body, parasites, conformation, endocrine disease, otitis media or another primary/perpetuating cause rather than repeatedly suppressing secondary infection.
  • Marbofloxacin is an EMA AMEG Category B fluoroquinolone. Do not use this combination prophylactically or as a routine first choice; use a lower-category topical option when likely effective and document why a fluoroquinolone is required. Culture and susceptibility are especially important with rods, chronic/recurrent disease or poor response.
  • Do not use when resistance to marbofloxacin or clotrimazole is known, or with hypersensitivity to fluoroquinolones, azole antifungals, corticosteroids or excipients. Failure despite correct administration requires diagnosis and susceptibility review, not automatic repetition or prolongation.
  • Avoid use in young growing dogs unless the exceptional need clearly outweighs the risk. Quinolones are associated with weight-bearing cartilage injury and arthropathy in immature animals.
  • Do not use during pregnancy or lactation. Record reproductive status before treatment and choose a suitable alternative for pregnant, breeding or nursing animals.
  • Clean and dry the external canal before dosing, shake the suspension as directed, instil exactly ten drops once daily and massage the ear base gently. Reassess at day 7 before extending to 14 days; use a separate cannula/dropper for each dog and do not continue beyond the labelled course.
  • Rare, usually transient deafness is reported, mainly in older dogs. Establish baseline hearing and neurologic status when relevant; stop and reassess promptly for reduced hearing, pain, marked erythema, vestibular signs or worsening discharge.
  • Prolonged or intensive topical corticosteroid exposure can cause skin thinning, delayed healing, biochemical/haematological changes and adrenal suppression. Avoid duplicate otic/systemic corticosteroids without review and investigate persistent inflammation rather than extending treatment.
  • Avoid skin and eye contact, wash hands after administration and keep the applicator uncontaminated. People hypersensitive to fluoroquinolones, azole antifungals or corticosteroids should avoid handling; seek medical advice after accidental ingestion or persistent exposure symptoms.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Marbofloxacin3 mg/ml Clotrimazole10 mg/ml Dexamethasone0.9 mg/ml
Formulation Type
Ear drops
Administration route
Into the ear
Manufacturer
Vet-Agro · Poland
Registration
Georgia No
EU Yes, veterinary
Verified on: 15 Oct 2026
UK Yes, veterinary
Verified on: 15 Oct 2026
US No
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Oftan Dexamethasone 1 mg/ml (0.1%), Eye drops

eye drops 5 ml, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
7.0/10
Good
vetman assessment

Oftan Dexamethasone

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeDog · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 7.0/10 Good
Evidence confidence: Medium Georgia: Yes, human · № რ-045645 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility6.5/10

This exact human 0.1% ophthalmic product has sourced current registrations in Georgia, EU/EEA and GB with an identifiable formulation and manufacturer; current US checking records no exact registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy8.0/10

Topical 0.1% dexamethasone is a standard, cornea-penetrating veterinary corticosteroid for noninfectious anterior ocular inflammation. Current canine data support improvement in moderate-to-severe follicular conjunctivitis and combination therapy for chronic superficial keratitis, while established use covers anterior uveitis, immune-mediated keratitis and episcleritis; diagnosis and cause-directed therapy determine benefit.

Safety and tolerability6.0/10

Correctly selected use is usually locally tolerable, but corticosteroids delay epithelial healing, increase collagenase activity and can convert an occult abrasion into a melting ulcer. Repeated treatment can increase intraocular pressure, promote infection, cataract and steroid keratopathy, and systemic absorption with cortisol suppression is documented after four-times-daily dosing.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Reassess the diagnosis urgently if blepharospasm, discharge, corneal clouding, focal staining, vision change or worsening redness appears; stop dexamethasone until ulceration and infection have been excluded.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.5/10
Situational / acceptable
vetman assessment

Oftan Dexamethasone

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeCat · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045645 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility6.5/10

This exact human 0.1% ophthalmic product has sourced current registrations in Georgia, EU/EEA and GB with an identifiable formulation and manufacturer; current US checking records no exact registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy7.0/10

Topical 0.1% dexamethasone is an established cornea-penetrating corticosteroid for selected noninfectious feline anterior ocular inflammation, including immune-mediated keratitis, conjunctival disease and anterior uveitis. Direct controlled feline efficacy data are limited, and latent FHV-1 or infectious disease can make an apparently inflammatory presentation steroid-inappropriate.

Safety and tolerability5.0/10

Corneal ulceration or untreated infection creates a serious local hazard, and feline herpesvirus may reactivate with topical steroid exposure, causing ulceration or sequestrum. Longer treatment can increase intraocular pressure, delay healing, promote infection or cataract and cause systemic glucocorticoid exposure; feline product-specific safety data are limited.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Topical corticosteroids can reactivate latent feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum. In a cat with compatible history or dendritic/geographic disease, stop steroid treatment and investigate/treat FHV-associated disease before considering further immunosuppression.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Santen · Finland
Registration
Georgia Yes, human
In force until 09 Jun 2031
Human (Ministry of Health, RAMA)
In the register: ოფთან დექსამეტაზონი 1 მგ/მლ (0.1%), თვალის წვეთები 5 მლ
№ რ-045645
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Otoxolan 3 mg/ml + 10 mg/ml + 1 mg/ml, Ear drops

ear drops suspension, for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.4/10
Good
vetman assessment

Otoxolan

3 mg/ml + 10 mg/ml + 1 mg/ml, ear drops suspension, for dogs
Assessed clinical scopeDog · Label-concordant treatment of canine otitis externa caused by marbofloxacin-susceptible bacteria and clotrimazole-susceptible fungi, especially Malassezia pachydermatis, with concurrent control of inflammation · Into the ear
Care settingVeterinary diagnosis and selection after otoscopy and cytology; outpatient administration after cleaning and drying, with day-7 veterinary reassessment and investigation of the underlying cause.
vetman score 7.4/10 Good
Evidence confidence: Medium Georgia: No · Verified on 15 Oct 2026

A good authorised generic option with regulator-accepted equivalence to Aurizon, but without an independent exact-product outcome trial. Use only after otoscopy and cytology, reserve the fluoroquinolone appropriately and reassess before extending beyond seven days.

Regulatory and scientific credibility8.5/10

Otoxolan has current exact EU/EEA and GB veterinary authorisations, regulator-hosted product information and a public generic dossier accepting qualitative and physicochemical equivalence to Aurizon. It is not registered in the checked Georgian or US registers.

Clinical efficacy7.0/10

The regulator accepted equivalent efficacy claims to Aurizon from matching composition and physicochemical characteristics; the reference combination has comparative canine evidence for bacterial/fungal otitis and Malassezia-associated inflammation. There is no independent exact-product outcome trial, and success still depends on cytology, susceptibility where indicated and control of the underlying cause.

Safety and tolerability7.0/10

Topical exposure is much lower than systemic treatment, but the intact tympanic membrane must be confirmed. Rare mostly transient deafness, local irritation and corticosteroid-related skin thinning, delayed healing, laboratory changes or adrenal suppression are possible; avoid pregnancy/lactation and unnecessary use in growing dogs.

Clinical practicality7.0/10

Ten drops once daily for 7-14 days is manageable, but the viscous suspension requires 30 seconds of shaking, dropper filling, a separate dropper per dog, prior cleaning/drying and veterinary reassessment at day 7. The fixed ten-drop dose and three-month in-use shelf life are practical but not long-acting.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform otoscopy and verify an intact tympanic membrane before every course. Do not use with a perforated or unvisualised tympanum; stop and reassess urgently for head tilt, nystagmus, ataxia, hearing change or other vestibular signs.
  • Cytology is required in every otitis externa case and should be repeated at recheck. Sample before cleaning; identify and manage allergy, foreign body, parasites, conformation, endocrine disease, otitis media or another primary/perpetuating cause rather than repeatedly suppressing secondary infection.
  • Marbofloxacin is an EMA AMEG Category B fluoroquinolone. Do not use this combination prophylactically or as a routine first choice; use a lower-category topical option when likely effective and document why a fluoroquinolone is required. Culture and susceptibility are especially important with rods, chronic/recurrent disease or poor response.
  • Do not use when resistance to marbofloxacin or clotrimazole is known, or with hypersensitivity to fluoroquinolones, azole antifungals, corticosteroids or excipients. Failure despite correct administration requires diagnosis and susceptibility review, not automatic repetition or prolongation.
  • Avoid use in young growing dogs unless the exceptional need clearly outweighs the risk. Quinolones are associated with weight-bearing cartilage injury and arthropathy in immature animals.
  • Do not use during pregnancy or lactation. Record reproductive status before treatment and choose a suitable alternative for pregnant, breeding or nursing animals.
  • Clean and dry the external canal before dosing, shake the suspension as directed, instil exactly ten drops once daily and massage the ear base gently. Reassess at day 7 before extending to 14 days; use a separate cannula/dropper for each dog and do not continue beyond the labelled course.
  • Rare, usually transient deafness is reported, mainly in older dogs. Establish baseline hearing and neurologic status when relevant; stop and reassess promptly for reduced hearing, pain, marked erythema, vestibular signs or worsening discharge.
  • Prolonged or intensive topical corticosteroid exposure can cause skin thinning, delayed healing, biochemical/haematological changes and adrenal suppression. Avoid duplicate otic/systemic corticosteroids without review and investigate persistent inflammation rather than extending treatment.
  • Avoid skin and eye contact, wash hands after administration and keep the applicator uncontaminated. People hypersensitive to fluoroquinolones, azole antifungals or corticosteroids should avoid handling; seek medical advice after accidental ingestion or persistent exposure symptoms.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Marbofloxacin3 mg/ml Clotrimazole10 mg/ml Dexamethasone0.9 mg/ml
Formulation Type
Ear drops
Administration route
Into the ear
Manufacturer
Krka · Slovenia
Registration
Georgia No
EU Yes, veterinary
Verified on: 15 Oct 2026
UK Yes, veterinary
Verified on: 15 Oct 2026
US No
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Pabi-Dexamethasone 8 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
6.1/10
Situational / acceptable
vetman assessment

Pabi-Dexamethasone

8 mg, tablet, human medicine
Assessed clinical scopeDog · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 6.1/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-045810 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 8 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, a current Polish regulator-hosted product label and no exact US registration in the checked register. Veterinary use remains off-label; the 8 mg unscored presentation is not interchangeable with a divisible 0.5 mg veterinary tablet.

Clinical efficacy7.5/10

Dexamethasone is a potent, well-absorbed, long-acting oral glucocorticoid, and a current authorised veterinary 0.5 mg product directly supports symptomatic or adjunct treatment of inflammatory and allergic disease in dogs. It can provide strong short-term control when the diagnosis and dose target are correct, but does not cure the underlying disease and is usually less suitable than a shorter-acting steroid for adjustable chronic therapy.

Safety and tolerability5.0/10

Short, appropriately selected courses can be manageable, but cortisol suppression is very common with the authorised veterinary comparator and long-acting dexamethasone can cause infection, gastrointestinal ulceration, metabolic effects, delayed healing and HPA-axis suppression. Long-term oral use is specifically discouraged when a shorter-acting alternative such as prednisolone can provide control.

Clinical practicality2.5/10

The stable tablet is easy to store, but the exact 8 mg presentation is unscored and its regulator label does not authorise division. Against the veterinary oral range, one whole tablet is practical only for a narrow high-dose or very-large-dog situation; routine small-animal dosing would require an independently validated compounded form or a lower-strength product.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring
5.8/10
Weak evidence support
vetman assessment

Pabi-Dexamethasone

8 mg, tablet, human medicine
Assessed clinical scopeCat · Systemic oral dexamethasone as short-term symptomatic or adjunct anti-inflammatory/immunosuppressive treatment for a diagnosed corticosteroid-responsive disease, with cause-directed care and monitoring · By mouth
Care settingVeterinarian-directed treatment, usually at home after diagnosis, with an exact weight-based dose, early reassessment, the shortest effective course and a planned taper when exposure is sustained
vetman score 5.8/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, human · № რ-045810 · Verified on 16 Oct 2026 Off-label use

A potent, evidence-supported oral glucocorticoid for selected short-term inflammatory or immune-mediated roles, but these exact human products remain off-label. Confirm the exact strength, use a measurable weight-based dose, treat the underlying cause, avoid preventable interactions and prefer a shorter-acting corticosteroid when prolonged adjustable therapy is required.

Regulatory and scientific credibility8.0/10

This exact human 8 mg tablet has current sourced registrations in Georgia, EU/EEA and GB, a current Polish regulator-hosted product label and no exact US registration in the checked register. Veterinary use remains off-label; the 8 mg unscored presentation is not interchangeable with a divisible 0.5 mg veterinary tablet.

Clinical efficacy7.5/10

A current authorised veterinary 0.5 mg product directly supports oral dexamethasone for inflammatory and allergic disease in cats, and a small prospective feline study found oral absorption and improvement in hypersensitivity dermatitis. The evidence supports useful short-term control, not every possible immune-mediated claim; response is diagnosis-dependent and treatment must remain adjunctive to cause control.

Safety and tolerability4.5/10

The authorised veterinary label documents very common cortisol suppression and broad glucocorticoid toxicity. In cats, controlled pilot data suggest greater diabetogenic effects than equipotent prednisolone, while prolonged immunosuppressive exposure can produce hyperglycaemia, infection, hepatopathy, skin/muscle change, gastrointestinal injury and adrenal suppression; this narrows the margin for chronic use.

Clinical practicality1.5/10

An unscored 8 mg tablet is grossly mismatched to the dose granularity usually needed in cats and its exact label does not authorise division. Accurate routine feline use requires a lower-strength veterinary presentation or a professionally validated compound; informal tablet fragmentation is not an acceptable dosing method.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use as a substitute for diagnosis or cause-directed treatment. Dexamethasone can suppress fever, pain and inflammation while infection, neoplasia, endocrine disease or another underlying disorder progresses.
  • Do not start immunosuppressive dexamethasone with an uncontrolled viral, fungal, bacterial or parasitic infection. Establish appropriate cause-directed control first or concurrently when steroid benefit is essential.
  • Avoid concurrent NSAIDs and use an indication-appropriate washout when switching; the combination materially increases gastrointestinal ulceration, perforation and bleeding risk. Avoid use with active gastrointestinal ulceration.
  • Avoid or use only after explicit benefit-risk assessment in diabetes mellitus, hyperadrenocorticism, uncontrolled hypertension, glaucoma, osteoporosis, important cardiac or renal dysfunction, corneal ulceration or major thrombotic risk.
  • Do not administer modified-live vaccines during immunosuppressive treatment. Review vaccination timing and expected immune response before and after systemic dexamethasone exposure.
  • Use only the exact prescribed strength and a dose that can be measured accurately. Do not split or crush an unscored tablet to improvise a small dose unless the exact product instruction and a validated preparation method support dose uniformity.
  • Use the lowest effective dose for the shortest effective period and reassess early. Dexamethasone is long acting; alternate-day dosing does not reliably allow HPA-axis recovery, and a shorter-acting corticosteroid is usually preferable for prolonged adjustable treatment.
  • After sustained supraphysiologic exposure, taper rather than stop abruptly. Monitor weight, appetite, water intake and urination, blood pressure, infection signs, CBC, chemistry, glucose and urine according to dose, duration and patient risk.
  • Review all concurrent medicines. Enzyme inducers may reduce exposure, potassium-depleting diuretics and cardiac glycosides increase electrolyte-related risk, insulin requirements may change and other immunosuppressants increase infection risk.
  • Safety of these exact human tablets in breeding, pregnant, lactating, neonatal or growing dogs and cats is not established. Dexamethasone can affect fetal development, parturition, growth and immune response; use only after a documented veterinary benefit-risk assessment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Adamed · Poland
Registration
Georgia Yes, human
In force until 29 Jun 2031
Human (Ministry of Health, RAMA)
In the register: პაბი-დექსამეტაზონი 8 მგ, აბი
№ რ-045810
Verified on: 16 Oct 2026
EU Yes, human
UK Yes, human
№ PL113110877, PL113110878, PL113110879, PL142510255
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Ronik 1 mg/ml (0.1%), Eye drops

eye drops 5 ml, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.8/10
Situational / acceptable
vetman assessment

Ronik

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeDog · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.8/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046410 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy8.0/10

Topical 0.1% dexamethasone is a standard, cornea-penetrating veterinary corticosteroid for noninfectious anterior ocular inflammation. Current canine data support improvement in moderate-to-severe follicular conjunctivitis and combination therapy for chronic superficial keratitis, while established use covers anterior uveitis, immune-mediated keratitis and episcleritis; diagnosis and cause-directed therapy determine benefit.

Safety and tolerability6.0/10

Correctly selected use is usually locally tolerable, but corticosteroids delay epithelial healing, increase collagenase activity and can convert an occult abrasion into a melting ulcer. Repeated treatment can increase intraocular pressure, promote infection, cataract and steroid keratopathy, and systemic absorption with cortisol suppression is documented after four-times-daily dosing.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Reassess the diagnosis urgently if blepharospasm, discharge, corneal clouding, focal staining, vision change or worsening redness appears; stop dexamethasone until ulceration and infection have been excluded.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea
6.2/10
Situational / acceptable
vetman assessment

Ronik

1 mg/ml (0.1%), eye drops 5 ml, human medicine
Assessed clinical scopeCat · Ophthalmic dexamethasone for diagnosed noninfectious steroid-responsive conjunctival, corneal or anterior-segment inflammation after complete examination and a fluorescein-negative intact cornea · Into the eye
Care settingVeterinarian-directed clinic or home treatment after slit-lamp or magnified examination, fluorescein staining and intraocular-pressure assessment where relevant, with scheduled early recheck and taper based on response
vetman score 6.2/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-046410 · Verified on 16 Oct 2026 Off-label use

A useful potent topical steroid for a diagnosed, noninfectious steroid-responsive eye disease when the cornea is intact. Its value depends on examination rather than brand familiarity: stain before treatment, exclude or control infection, monitor pressure and response, taper longer courses, and stop immediately if pain, discharge or corneal damage emerges.

Regulatory and scientific credibility5.5/10

This exact human 0.1% ophthalmic product has a sourced current Georgian registration and identifiable formulation and manufacturer; exhaustive current checks record no exact EU/EEA, GB or US registration. Veterinary use is off-label, although an EU-authorised dog/cat veterinary dexamethasone eye-drop solution supports the species, route and concentration.

Clinical efficacy7.0/10

Topical 0.1% dexamethasone is an established cornea-penetrating corticosteroid for selected noninfectious feline anterior ocular inflammation, including immune-mediated keratitis, conjunctival disease and anterior uveitis. Direct controlled feline efficacy data are limited, and latent FHV-1 or infectious disease can make an apparently inflammatory presentation steroid-inappropriate.

Safety and tolerability5.0/10

Corneal ulceration or untreated infection creates a serious local hazard, and feline herpesvirus may reactivate with topical steroid exposure, causing ulceration or sequestrum. Longer treatment can increase intraocular pressure, delay healing, promote infection or cataract and cause systemic glucocorticoid exposure; feline product-specific safety data are limited.

Clinical practicality8.0/10

A ready-to-use solution and standard dropper provide a directly deliverable ocular dose with no weight calculation. Frequent initial dosing, atraumatic restraint, avoiding tip contact, spacing multiple eye medicines, storage/open-bottle rules and scheduled re-examination still determine whether treatment is practical and safe.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Perform fluorescein staining before starting and whenever new pain develops. Do not use topical dexamethasone with a corneal abrasion, ulcer, descemetocele, melting ulcer, perforation or unhealed penetrating injury; it delays epithelial repair and can accelerate collagenolysis.
  • Do not use as steroid monotherapy for an undiagnosed red eye or untreated bacterial, fungal, mycobacterial, parasitic or viral ocular infection. Establish and treat the cause; immunosuppression can mask progression and allow rapid loss of corneal integrity.
  • Topical corticosteroids can reactivate latent feline herpesvirus and precipitate ulcerative keratitis or corneal sequestrum. In a cat with compatible history or dendritic/geographic disease, stop steroid treatment and investigate/treat FHV-associated disease before considering further immunosuppression.
  • Measure intraocular pressure when glaucoma is possible and during repeated or prolonged treatment. Topical dexamethasone can raise pressure, cause glaucoma or cataract and promote steroid keratopathy; monitor the cornea, lens and treatment response rather than renewing indefinitely.
  • Ophthalmic dexamethasone is systemically absorbed. Four-times-daily dosing for 14 days suppressed cortisol in healthy dogs; use the lowest effective frequency, consider nasolacrimal occlusion, and review diabetes, hyperadrenocorticism, infection risk and concurrent systemic corticosteroids.
  • Use an indication-appropriate initial frequency and recheck early; severe anterior inflammation may need frequent treatment, whereas chronic immune-mediated disease requires response-guided tapering. Do not stop a prolonged course abruptly or continue unchanged without confirming control.
  • This score covers diagnosed steroid-responsive ocular inflammation as a clinical class, not every human-label indication and not posterior-segment disease that topical drops cannot adequately reach. Lack of response should trigger diagnostic reassessment, not automatic dose escalation.
  • Avoid touching the dropper tip to the eye, lashes or skin; use one bottle per patient where contamination is plausible and separate different eye drops by at least several minutes. Shake suspension products thoroughly before every dose.
  • Safety of these exact human products in pregnant or lactating dogs and cats has not been established. Use only after a documented veterinary benefit-risk assessment, especially for prolonged or bilateral treatment that increases systemic exposure.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Laboratorio Edol · Portugal
Registration
Georgia Yes, human
In force until 02 Oct 2031
Human (Ministry of Health, RAMA)
In the register: რონიკი 1 მგ/მლ (0.1%), თვალის წვეთები 5 მლ
№ რ-046410
Verified on: 16 Oct 2026
EU No
UK No
Verified on: 16 Oct 2026
US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

TobraDex 3 mg/g + 1 mg/g, Ointment

eye ointment 3.5 g, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when susceptible superficial bacterial infection or a clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact
4.6/10
Weak evidence support
vetman assessment

TobraDex

3 mg/g + 1 mg/g, eye ointment 3.5 g, human medicine
Assessed clinical scopeDog · Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when susceptible superficial bacterial infection or a clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact · Into the eye
Care settingVeterinarian-directed clinic or closely supervised home treatment after complete ocular examination, staining and infection assessment, with IOP monitoring where relevant and an early scheduled recheck
vetman score 4.6/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, human · № რ-043983 · Verified on 22 Oct 2026 Off-label use

A weak off-label option for a narrow, fully examined canine case in which both steroid-responsive inflammation and susceptible superficial bacterial infection/risk genuinely coexist. Exact product quality is strong, but benefit rests on one confounded case and indirect evidence, while diagnostic error can be vision-threatening.

Regulatory and scientific credibility4.0/10

The exact 3 mg/g + 1 mg/g 3.5 g human ointment has transparent NDA 050616 identity and current Georgian, EU/EEA and US human authorisations. The inherited GB row was a suspension mismatch and is corrected to unknown exact-form status. No veterinary authorisation exists, and exact-product target-species evidence is absent or limited to one confounded canine case; the evidence gate caps this axis at 4.0.

Clinical efficacy4.0/10

One exact-ointment canine MGD/blepharitis case improved during ointment plus systemic doxycycline, warm compresses, lid massage and dermatologic care; it cannot isolate efficacy or generalise across ocular disease. Exact rabbit PK confirms delivery but not canine benefit, and dexamethasone increased tobramycin resistance/MIC in canine S. pseudintermedius isolates.

Safety and tolerability4.5/10

Correct selection can reduce harm, but dexamethasone can delay epithelial healing, mask or enhance infection, raise IOP and contribute to perforation in thinned cornea; the ointment itself may retard healing. Repeated topical 0.1% dexamethasone produced systemic absorption and cortisol suppression in dogs. Exact repeated-ointment target-animal safety is absent.

Clinical practicality6.5/10

The sterile ready tube needs no shaking and longer surface residence may suit selected lid/anterior-surface disease. Ribbon length is imprecise, ointment blurs vision and requires atraumatic restraint, tip hygiene and placement after other drops; examination, IOP decisions and early recheck remain substantial but appropriate clinical work.

Full-course cost-effectiveness-

A current comparable Georgian full-course price and exact veterinary regimen were not verified; cost is excluded from the denominator.

Important safety and use flags

  • This score covers only steroid-responsive anterior ocular inflammation where susceptible superficial bacterial infection or a meaningful infection risk also exists and the cornea is intact. It is not a score for every red eye, ulcer or labelled human indication.
  • Human ophthalmic ointment; all dog/cat use is off-label. Exact product is 3 mg/g tobramycin plus 1 mg/g dexamethasone under NDA 050616. Do not transfer this score or handling to suspension NDA 050592, TobraDex ST, pure Tobrex or systemic/otic products.
  • Perform a complete ocular examination and fluorescein stain before the first dose and at deterioration. Corneal ulcer, epithelial defect, thinning, melting or suspected penetration is a hard stop for topical dexamethasone and requires urgent cause-directed ophthalmology care.
  • Exclude epithelial herpesvirus, fungal and mycobacterial disease and untreated purulent or parasitic infection. In cats, compatible history or dendritic/geographic ulceration should trigger FHV-directed assessment rather than empirical steroid exposure.
  • The antibiotic does not neutralise steroid risk. Dexamethasone can mask or enhance infection and increased tobramycin resistance/MIC in canine S. pseudintermedius isolates; obtain cytology/culture when substantial, recurrent, treated or poorly responsive.
  • Monitor IOP when glaucoma is possible and during repeated treatment. Stop and reassess for pressure rise, vision change, cataract, increasing pain, discharge, corneal opacity or absent early improvement; do not renew indefinitely without examination.
  • Topical dexamethasone can be systemically absorbed. Repeated 0.1% ocular exposure suppressed cortisol in healthy dogs; use the lowest justified exposure and review diabetes, hyperadrenocorticism, infection risk, CYP3A4 inhibitors and concurrent steroids.
  • Ointment may retard corneal wound healing. Ribbon length is less precise than a drop and the human half-inch schedule is not a dog/cat default; select frequency, duration and taper from diagnosis and early response.
  • Avoid contamination: wash hands, do not touch the tube tip to eye, lashes, skin or fingers, recap promptly and do not share between patients. Stop for aminoglycoside hypersensitivity or non-susceptible bacterial/fungal overgrowth.
  • Ointment can temporarily blur vision and should generally be placed after other ophthalmic drops. Record all concurrent ocular products so the petrolatum vehicle does not block earlier drops and a duplicate steroid or aminoglycoside is not overlooked.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when susceptible superficial bacterial infection or a clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact
4.3/10
Weak evidence support
vetman assessment

TobraDex

3 mg/g + 1 mg/g, eye ointment 3.5 g, human medicine
Assessed clinical scopeCat · Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when susceptible superficial bacterial infection or a clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact · Into the eye
Care settingVeterinarian-directed clinic or closely supervised home treatment after complete ocular examination, staining and infection assessment, with IOP monitoring where relevant and an early scheduled recheck
vetman score 4.3/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, human · № რ-043983 · Verified on 22 Oct 2026 Off-label use

A weak off-label feline option: no exact clinical outcome exists and common herpesvirus-associated disease can make dexamethasone dangerous. Consider only when both components are independently justified, the cornea is intact and viral/fungal/purulent disease has been excluded.

Regulatory and scientific credibility4.0/10

The exact 3 mg/g + 1 mg/g 3.5 g human ointment has transparent NDA 050616 identity and current Georgian, EU/EEA and US human authorisations. The inherited GB row was a suspension mismatch and is corrected to unknown exact-form status. No veterinary authorisation exists, and exact-product target-species evidence is absent or limited to one confounded canine case; the evidence gate caps this axis at 4.0.

Clinical efficacy4.0/10

No exact-ointment feline outcome trial was found. Human-label activity, rabbit PK and one confounded canine case are indirect, while common feline herpesvirus disease can make the steroid inappropriate; pure-tobramycin susceptibility cannot prove benefit of this fixed combination.

Safety and tolerability4.0/10

Ulcer, delayed-healing, infection, IOP and perforation hazards apply, while latent feline herpesvirus adds a species-specific risk. Exact feline PK and repeated-use safety are absent; aminoglycoside hypersensitivity, contamination and non-susceptible overgrowth remain possible.

Clinical practicality6.0/10

A ready tube and longer residence may reduce placements, but ribbon length is difficult to quantify in a small painful eye. Greasy residue, temporary blur, restraint, contamination control, other-drop sequencing and early reassessment limit practicality, especially when FHV or another differential may require changing one component.

Full-course cost-effectiveness-

A current comparable Georgian full-course price and exact veterinary regimen were not verified; cost is excluded from the denominator.

Important safety and use flags

  • This score covers only steroid-responsive anterior ocular inflammation where susceptible superficial bacterial infection or a meaningful infection risk also exists and the cornea is intact. It is not a score for every red eye, ulcer or labelled human indication.
  • Human ophthalmic ointment; all dog/cat use is off-label. Exact product is 3 mg/g tobramycin plus 1 mg/g dexamethasone under NDA 050616. Do not transfer this score or handling to suspension NDA 050592, TobraDex ST, pure Tobrex or systemic/otic products.
  • Perform a complete ocular examination and fluorescein stain before the first dose and at deterioration. Corneal ulcer, epithelial defect, thinning, melting or suspected penetration is a hard stop for topical dexamethasone and requires urgent cause-directed ophthalmology care.
  • Exclude epithelial herpesvirus, fungal and mycobacterial disease and untreated purulent or parasitic infection. In cats, compatible history or dendritic/geographic ulceration should trigger FHV-directed assessment rather than empirical steroid exposure.
  • The antibiotic does not neutralise steroid risk. Dexamethasone can mask or enhance infection and increased tobramycin resistance/MIC in canine S. pseudintermedius isolates; obtain cytology/culture when substantial, recurrent, treated or poorly responsive.
  • Monitor IOP when glaucoma is possible and during repeated treatment. Stop and reassess for pressure rise, vision change, cataract, increasing pain, discharge, corneal opacity or absent early improvement; do not renew indefinitely without examination.
  • Topical dexamethasone can be systemically absorbed. Repeated 0.1% ocular exposure suppressed cortisol in healthy dogs; use the lowest justified exposure and review diabetes, hyperadrenocorticism, infection risk, CYP3A4 inhibitors and concurrent steroids.
  • Ointment may retard corneal wound healing. Ribbon length is less precise than a drop and the human half-inch schedule is not a dog/cat default; select frequency, duration and taper from diagnosis and early response.
  • Avoid contamination: wash hands, do not touch the tube tip to eye, lashes, skin or fingers, recap promptly and do not share between patients. Stop for aminoglycoside hypersensitivity or non-susceptible bacterial/fungal overgrowth.
  • Ointment can temporarily blur vision and should generally be placed after other ophthalmic drops. Record all concurrent ocular products so the petrolatum vehicle does not block earlier drops and a duplicate steroid or aminoglycoside is not overlooked.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Ointment
Administration route
Into the eye
Manufacturer
Registration
Georgia Yes, human
In force until 12 Sep 2030
Human (Ministry of Health, RAMA)
In the register: ტობრადექსი 3 მგ/გ + 1 მგ/გ, თვალის მალამო 3.5 გ
№ რ-043983
Verified on: 22 Oct 2026
EU Yes, human
UK Not confirmed
Verified on: 22 Oct 2026
US Yes, human
№ NDA 050616
Verified on: 22 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified For ophthalmic use only. No universal dog/cat ribbon length or frequency is published here; the human half-inch ribbon schedule is not transferred. Use only after complete ocular examination, fluorescein staining and infection assessment establish that steroid and antibacterial components are simultaneously justified. Monitor IOP where relevant and recheck early. Place ointment after other ophthalmic drops and avoid tube-tip contact.

TobraDex 3 mg/ml + 1 mg/ml, Eye drops

ophthalmic suspension, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when a susceptible superficial bacterial infection or clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact
6.0/10
Situational / acceptable
vetman assessment

TobraDex

3 mg/ml + 1 mg/ml, ophthalmic suspension, human medicine
Assessed clinical scopeDog · Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when a susceptible superficial bacterial infection or clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact · Into the eye
Care settingVeterinarian-directed clinic or closely supervised home use after complete ophthalmic examination, staining and infection assessment, with IOP monitoring where relevant and an early scheduled recheck
vetman score 6.0/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043918 · Verified on 22 Oct 2026 Off-label use

A situational off-label fixed combination for a narrow, fully examined canine case in which steroid-responsive inflammation and superficial susceptible bacterial infection/risk genuinely coexist and the cornea is intact. Direct canine use is documented but confounded by co-treatment, and dexamethasone can worsen healing, infection and even tobramycin susceptibility; stain, assess IOP/infection and recheck early.

Regulatory and scientific credibility8.0/10

The exact 0.3%/0.1% human suspension has transparent FDA NDA 050592 identity and current Georgian, EU/EEA, GB and US human authorisations. The old NDA 050616 mapping belonged to ointment and is corrected here; no veterinary authorisation applies and dog/cat use remains off-label.

Clinical efficacy5.5/10

Exact TobraDex is documented in canine cataract and lens-emergency protocols, supporting a real narrow veterinary role, but outcomes are inseparable from surgery and multiple concurrent drugs. No clean exact-product canine trial was found, and a 2026 study found dexamethasone increased tobramycin resistance/MIC in canine S. pseudintermedius isolates.

Safety and tolerability4.5/10

A diagnostic error can cause vision-threatening harm: dexamethasone delays epithelial healing, can enhance collagenase-associated melting, mask infection and raise IOP. Four-times-daily 0.1% ophthalmic dexamethasone produced systemic absorption and cortisol suppression in dogs; BAK exposure, aminoglycoside sensitivity and microbial overgrowth add risk.

Clinical practicality6.0/10

The 5 ml dropper gives a direct ocular unit without weight calculation, but this suspension must be shaken before every dose and needs repeated administration, careful restraint, contamination control, examination, IOP decisions and early recheck. A fixed combination is less adaptable when only one component should be changed.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • This score covers only steroid-responsive anterior ocular inflammation where susceptible superficial bacterial infection or a meaningful infection risk also exists and the cornea is intact. It is not a score for every labelled human indication, every red eye or bacterial keratitis generally.
  • TobraDex is a human medicine and all dog/cat use is off-label. This exact suspension is 3 mg/ml tobramycin plus 1 mg/ml dexamethasone under FDA NDA 050592; do not transfer the score or regimen to NDA 050616 ointment, 0.05% TobraDex ST, pure Tobrex, fortified or systemic products.
  • Perform a complete ocular examination and fluorescein stain before the first dose and at any deterioration. A corneal ulcer, epithelial defect, thinning, melting or suspected penetration is a hard stop for topical dexamethasone and requires urgent cause-directed ophthalmology care.
  • Exclude epithelial herpesvirus disease, fungal or mycobacterial infection and untreated purulent infection before use. In cats, compatible history or dendritic/geographic ulceration should trigger FHV-directed evaluation rather than empirical steroid exposure.
  • The antibacterial component does not neutralise steroid risk. Dexamethasone can mask or enhance infection and a 2026 canine-isolate study found increased tobramycin resistance/MIC in S. pseudintermedius; obtain cytology/culture when infection is substantial, recurrent, previously treated or poorly responsive.
  • Monitor intraocular pressure when glaucoma is possible and during repeated treatment. Stop and reassess for pressure rise, vision change, cataract, increasing pain, discharge, corneal opacity or absent early improvement; never renew a fixed steroid combination indefinitely without examination.
  • Topical dexamethasone can be systemically absorbed. Four-times-daily 0.1% exposure for 14 days suppressed cortisol in healthy dogs; use the lowest justified exposure, consider nasolacrimal occlusion and review diabetes, hyperadrenocorticism, infection risk and concurrent steroids.
  • Shake the suspension thoroughly before every dose. Avoid tip contact, keep one bottle per patient where contamination is plausible, separate other eye drops by at least five minutes, apply ointment last and discard the opened bottle according to its exact label.
  • The exact suspension contains benzalkonium chloride 0.01%. Monitor irritation and compromised ocular surfaces, and stop for aminoglycoside hypersensitivity; prolonged antibiotic exposure can select non-susceptible bacteria or fungi.
  • No universal dog/cat schedule is published here. Canine postoperative and lens-emergency reports used TobraDex inside complex protocols and do not establish a transferable dose for every diagnosis; choose frequency, duration and taper from the diagnosed condition and recheck response early.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when a susceptible superficial bacterial infection or clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact
5.5/10
Weak evidence support
vetman assessment

TobraDex

3 mg/ml + 1 mg/ml, ophthalmic suspension, human medicine
Assessed clinical scopeCat · Topical treatment of diagnosed steroid-responsive anterior ocular inflammation only when a susceptible superficial bacterial infection or clinically meaningful infection risk also exists and the cornea is fluorescein-negative and intact · Into the eye
Care settingVeterinarian-directed clinic or closely supervised home use after complete ophthalmic examination, staining and infection assessment, with IOP monitoring where relevant and an early scheduled recheck
vetman score 5.5/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, human · № რ-043918 · Verified on 22 Oct 2026 Off-label use

A weak off-label feline option because exact clinical benefit is unproven and common herpesvirus-associated disease can make the steroid dangerous. Consider it only when both components are independently justified, the cornea is intact and viral/fungal/purulent disease has been excluded; otherwise use separable cause-directed treatment.

Regulatory and scientific credibility8.0/10

The exact 0.3%/0.1% human suspension has transparent FDA NDA 050592 identity and current Georgian, EU/EEA, GB and US human authorisations. The old NDA 050616 mapping belonged to ointment and is corrected here; no veterinary authorisation applies and dog/cat use remains off-label.

Clinical efficacy4.5/10

No exact-product feline clinical outcome trial was found. Human exact-ratio data and canine multi-treatment experience provide only an indirect bridge, while common feline inflammatory eye disease may be herpetic and therefore steroid-inappropriate; pure-tobramycin susceptibility cannot prove benefit of the fixed combination.

Safety and tolerability4.0/10

The serious ulcer, infection, healing and IOP hazards apply, and topical corticosteroids can reactivate latent feline herpesvirus with ulcerative keratitis or sequestrum. Exact-product feline safety and systemic-absorption data are absent, so an intact stain today does not remove the need for viral history, lesion assessment and early recheck.

Clinical practicality5.5/10

The dropper is directly measurable, but shaking, repeated atraumatic feline restraint, contamination control, examination and early recheck are material burdens. The fixed combination is particularly inflexible when herpesvirus or another differential makes dexamethasone inappropriate while antibacterial treatment is still being reconsidered.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • This score covers only steroid-responsive anterior ocular inflammation where susceptible superficial bacterial infection or a meaningful infection risk also exists and the cornea is intact. It is not a score for every labelled human indication, every red eye or bacterial keratitis generally.
  • TobraDex is a human medicine and all dog/cat use is off-label. This exact suspension is 3 mg/ml tobramycin plus 1 mg/ml dexamethasone under FDA NDA 050592; do not transfer the score or regimen to NDA 050616 ointment, 0.05% TobraDex ST, pure Tobrex, fortified or systemic products.
  • Perform a complete ocular examination and fluorescein stain before the first dose and at any deterioration. A corneal ulcer, epithelial defect, thinning, melting or suspected penetration is a hard stop for topical dexamethasone and requires urgent cause-directed ophthalmology care.
  • Exclude epithelial herpesvirus disease, fungal or mycobacterial infection and untreated purulent infection before use. In cats, compatible history or dendritic/geographic ulceration should trigger FHV-directed evaluation rather than empirical steroid exposure.
  • The antibacterial component does not neutralise steroid risk. Dexamethasone can mask or enhance infection and a 2026 canine-isolate study found increased tobramycin resistance/MIC in S. pseudintermedius; obtain cytology/culture when infection is substantial, recurrent, previously treated or poorly responsive.
  • Monitor intraocular pressure when glaucoma is possible and during repeated treatment. Stop and reassess for pressure rise, vision change, cataract, increasing pain, discharge, corneal opacity or absent early improvement; never renew a fixed steroid combination indefinitely without examination.
  • Topical dexamethasone can be systemically absorbed. Four-times-daily 0.1% exposure for 14 days suppressed cortisol in healthy dogs; use the lowest justified exposure, consider nasolacrimal occlusion and review diabetes, hyperadrenocorticism, infection risk and concurrent steroids.
  • Shake the suspension thoroughly before every dose. Avoid tip contact, keep one bottle per patient where contamination is plausible, separate other eye drops by at least five minutes, apply ointment last and discard the opened bottle according to its exact label.
  • The exact suspension contains benzalkonium chloride 0.01%. Monitor irritation and compromised ocular surfaces, and stop for aminoglycoside hypersensitivity; prolonged antibiotic exposure can select non-susceptible bacteria or fungi.
  • No universal dog/cat schedule is published here. Canine postoperative and lens-emergency reports used TobraDex inside complex protocols and do not establish a transferable dose for every diagnosis; choose frequency, duration and taper from the diagnosed condition and recheck response early.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Tobramycin3 mg/ml Dexamethasone1 mg/ml
Formulation Type
Eye drops
Administration route
Into the eye
Manufacturer
Alcon · Switzerland
Registration
Georgia Yes, human
EU Yes, human
UK Yes, human
№ PL238600036, PLPI163691794, PLPI187992985, PLPI187993010
Verified on: 16 Oct 2026
US Yes, human
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified For ophthalmic use only; shake thoroughly before every dose. No single diagnosis-independent dog/cat frequency is published here. Use only after a complete examination, fluorescein staining and infection assessment show that both steroid and antibacterial components are simultaneously appropriate; monitor IOP where relevant and recheck early.

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.