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Nobivac Lepto

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Leptospira canicola + Leptospira icterohaemorrhagiae · Intervet International B.V.

1 form: suspension. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Form Species Dose Frequency Georgia
Suspension · Dog Dog 1 ml
Inject one 1 ml dose subcutaneously. Give two primary doses 2-4 weeks apart, starting from 8 weeks of age. Revaccinate every 6-12 months; a 6-month interval is recommended for clinical protection against Icterohaemorrhagiae. Vaccinate healthy animals only. The current official instructions permit use during pregnancy. Hypersensitivity or anaphylaxis requires immediate treatment; rare immune-mediated haemolytic anaemia, thrombocytopenia or polyarthritis is described.
 · two doses 2-4 weeks apart, then every 6-12 months		 two doses 2-4 weeks apart, then every 6-12 months Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ნობივაკ ლეპტო
№ 180-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Nobivac Lepto, Suspension

suspension for injection, 1 ml dose for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.5/10
Good
vetman assessment

Nobivac Lepto

suspension for injection, 1 ml dose for dogs
Assessed clinical scopeDog · Full dog label from 8 weeks: reduce clinical leptospirosis, bacteraemia and leptospiruria caused by the included Canicola and Icterohaemorrhagiae serogroups · Subcutaneous
Care settingPreventive veterinary vaccination with examination, cold-chain control and emergency treatment available
vetman score 7.5/10 Good
Evidence confidence: High Georgia: Yes, veterinary · № 180-11 · Verified on 21 Oct 2026

A well-characterised bivalent leptospirosis vaccine that can protect against its two included serogroups, but it is a narrower and more frequently repeated option than modern four-serovar products and should be chosen only after local epidemiologic comparison.

Regulatory and scientific credibility9.0/10

The exact one-dose product is registered in Georgia and has a current regulator-hosted EU SPC with transparent potency, compatibility, safety frequencies and six- versus twelve-month duration claims.

Clinical efficacy6.5/10

Vaccination against leptospirosis is strongly supported, but protection is predominantly serogroup-specific: this bivalent Canicola/Icterohaemorrhagiae product omits other currently important serogroups, and its Icterohaemorrhagiae clinical duration is only six months.

Safety and tolerability7.5/10

Most reactions are local and transient and use in pregnancy is permitted, but swelling is very common, anaphylaxis can be life-threatening and very rare immune-mediated haemolytic anaemia, thrombocytopenia or polyarthritis is labelled.

Clinical practicality6.5/10

The fixed 1 ml dose and authorised mixing with selected Nobivac vaccines are helpful, but two priming visits and six-month revaccination for the shorter component create more burden than current annual four-serovar alternatives.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • This bivalent vaccine covers Canicola and Icterohaemorrhagiae; vaccine protection is largely serogroup-specific and does not reliably substitute for missing relevant serogroups.
  • Give two primary doses 2-4 weeks apart. For Icterohaemorrhagiae clinical protection the label recommends revaccination every 6 months rather than relying on an annual interval.
  • Hypersensitivity and anaphylaxis can be life-threatening; observe after vaccination and have immediate treatment available.
  • Injection-site swelling is very common and may be firm or painful. Very rare immune-mediated haemolytic anaemia, thrombocytopenia and polyarthritis are labelled.
  • The current product information permits use during pregnancy; vaccinate healthy animals only.
  • Mix only with the specifically authorised compatible Nobivac vaccines and give same-day Nobivac Rabies separately as directed; other combinations require individual assessment.
  • Bring the vial to room temperature, maintain refrigerated storage, do not freeze and use immediately after opening.
Assessment sources
  1. EU UPD Nobivac Lepto2026
  2. ACVIM leptospirosis consensus 20232023
  3. Leptospirosis vaccine meta-analysis2022
  4. AAHA canine vaccination 20222022
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Leptospira canicola990 ELISA units/dose Leptospira icterohaemorrhagiae699 ELISA units/dose
Formulation Type
Suspension
Administration route
Subcutaneous
Manufacturer
Intervet International B.V. · Netherlands
Manufacturer (register)
Intervet International B.V., Netherlands
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 132, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ნობივაკ ლეპტო
№ 180-11
Verified on: 21 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
1 ml
Inject one 1 ml dose subcutaneously. Give two primary doses 2-4 weeks apart, starting from 8 weeks of age. Revaccinate every 6-12 months; a 6-month interval is recommended for clinical protection against Icterohaemorrhagiae. Vaccinate healthy animals only. The current official instructions permit use during pregnancy. Hypersensitivity or anaphylaxis requires immediate treatment; rare immune-mediated haemolytic anaemia, thrombocytopenia or polyarthritis is described.
 Dog Any weight Subcutaneous two doses 2-4 weeks apart, then every 6-12 months
EU UPD Nobivac Lepto
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nobivac Lepto - official product information
EU Union Product Database, 2026

Leptospira canicola: No dose supported by a publicly verifiable source yet

Leptospira icterohaemorrhagiae: No dose supported by a publicly verifiable source yet

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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