KA/EN
Register
Medicines reference
Search
Search
Product

Nobivac RL

Favourites

Rabies virus + Leptospira canicola + Leptospira icterohaemorrhagiae · Intervet International B.V.

1 form: suspension. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Form Species Dose Frequency Georgia
Suspension · Dog Dog 1 ml
Inject one 1 ml dose subcutaneously. A compatible first leptospirosis dose may be given from 8 weeks; give Nobivac RL 2-4 weeks later and not before 12 weeks. Revaccinate leptospirosis annually and rabies at least every 3 years, subject to local law. Vaccinate healthy dogs only. Very rare mild hypersensitivity or local inflammatory swelling can occur. May be used during pregnancy and lactation.
 · primary series, then component-specific revaccination		 primary series, then component-specific revaccination Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ნობივაკი RL
№ 177-11; 287-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Nobivac RL, Suspension

suspension for injection, 1 ml dose for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.1/10
Very good
vetman assessment

Nobivac RL

suspension for injection, 1 ml dose for dogs
Assessed clinical scopeDog · Full dog label: active immunisation against rabies and leptospirosis caused by the labelled Canicola and Icterohaemorrhagiae serogroups, with component-specific revaccination · Subcutaneous
Care settingPreventive canine vaccination with examination, legal rabies scheduling, exposure-risk assessment, cold-chain control and emergency treatment available
vetman score 8.1/10 Very good
Evidence confidence: Medium Georgia: Yes, veterinary · № 177-11; 287-11 · Verified on 21 Oct 2026

A practical rabies-plus-leptospirosis combination with strong rabies value and a favourable safety profile. Its main weakness is the older bivalent leptospiral breadth and the need to manage two different booster intervals.

Regulatory and scientific credibility8.8/10

The exact 1 ml combination is actively registered in Georgia and supported by current official product information specifying antigens, potency, schedule, pregnancy use and adverse reactions.

Clinical efficacy7.5/10

Rabies vaccination has a strong evidence and public-health basis and the label supports a three-year rabies interval. The leptospiral component requires annual boosting and covers only two traditional serogroups, so protection should not be assumed against the broader epidemiological range.

Safety and tolerability8.2/10

The inactivated combination has a favourable profile, may be used during pregnancy and lactation, and reactions are generally mild and very rare; hypersensitivity still requires immediate readiness.

Clinical practicality8.0/10

A fixed 1 ml ready-to-use SC dose combines two targets and avoids reconstitution; annual leptospirosis versus at-least-three-year rabies timing, legal requirements and age-dependent priming still require careful records.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Vaccinate healthy dogs only; do not use in hypersensitivity to a component.
  • Leptospiral coverage is limited to the Canicola and Icterohaemorrhagiae serogroups; do not infer broader serogroup protection.
  • Revaccinate leptospirosis annually but rabies at least every three years, subject to Georgian law and travel rules.
  • For primary vaccination, give the compatible first leptospirosis dose from 8 weeks and Nobivac RL 2-4 weeks later, not before 12 weeks.
  • Very rare hypersensitivity may require immediate treatment; observe for local inflammatory swelling or systemic reaction.
  • Use concurrent or mixed vaccines only where the exact SPC supports the combination; otherwise decide case by case.
  • The label permits use during pregnancy and lactation; maintain the cold chain and use the complete 1 ml SC dose.
Assessment sources
  1. EU UPD SPC 20262026
  2. WSAVA vaccination 20242024
  3. AAHA canine vaccination 20222022
  4. ACVIM leptospirosis consensus 20232023
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Rabies virus3 IU/dose Leptospira canicola40 hamster PD80/dose Leptospira icterohaemorrhagiae40 hamster PD80/dose
Formulation Type
Suspension
Administration route
Subcutaneous
Manufacturer
Intervet International B.V. · Netherlands
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ნობივაკი RL
№ 177-11; 287-11
Verified on: 21 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
1 ml
Inject one 1 ml dose subcutaneously. A compatible first leptospirosis dose may be given from 8 weeks; give Nobivac RL 2-4 weeks later and not before 12 weeks. Revaccinate leptospirosis annually and rabies at least every 3 years, subject to local law. Vaccinate healthy dogs only. Very rare mild hypersensitivity or local inflammatory swelling can occur. May be used during pregnancy and lactation.
 Dog Any weight Subcutaneous primary series, then component-specific revaccination
EU UPD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nobivac RL - official product information
EU Union Product Database, 2026

Rabies virus: No dose supported by a publicly verifiable source yet

Leptospira canicola: No dose supported by a publicly verifiable source yet

Leptospira icterohaemorrhagiae: No dose supported by a publicly verifiable source yet

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

Trademarks belong to their owners; vetman is not affiliated with the manufacturers and receives no payment from them.

The database is protected under Chapter VII of the Law of Georgia on Copyright and Related Rights; automated or bulk copying is prohibited.

This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

Register Demo ↗