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Active substance

Clavulanic Acid

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Beta-lactamase inhibitor. Registered in Georgia: 8 veterinary products and 2 human medicines. Forms: coated tablet, powder, scored tablet, suspension, tablet.

Dose and use

Doses

Each dose comes with its source. Check the label of the product you use.

Active substance Clavulanic Acid
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
2.5 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox palatable tablets 200 mg/50 mg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
Before use

Safety information

No sourced safety entry is currently shown. This does not mean the substance is risk-free.

Latin name
Clavulanic Acid
Georgian name
კლავულანის მჟავა
Authorisation status
Authorised veterinary medicine
An authorised veterinary medicine containing this substance exists. Whether a particular use is on-label depends on the species and the indication - see each dose rule.
Registered in Georgia
10 of 10 forms
Products
Augmentin, Aurobindo Amoxicillin/Clavulanate, Cladaxxa, Nicilan, Synuxol-Nita
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
All forms and registration10

Registration in Georgia and abroad: the register, number, validity and source are behind (i).

Augmentin 228 mg/5 ml, Powder

powder for oral suspension, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Proposed oral treatment of a susceptible bacterial infection with exact Augmentin 228 mg/5 ml, a 7:1 human suspension without a validated dog/cat dose bridge
Not rateable
No numerical score assigned
vetman assessment

Augmentin

228 mg/5 ml, powder for oral suspension, human medicine
Assessed clinical scopeDog · Proposed oral treatment of a susceptible bacterial infection with exact Augmentin 228 mg/5 ml, a 7:1 human suspension without a validated dog/cat dose bridge · By mouth
Care settingVeterinarian-directed antimicrobial selection after diagnosis, susceptibility and exact presentation review
vetman score Not rateable No numerical score assigned
Evidence confidence: Medium Georgia: Yes, human · № რ-043538 · Verified on 15 Oct 2026 Off-label use
Not rateable

A numerical score cannot responsibly be assigned to this exact 7:1 suspension in dogs or cats. The prior 0.25 ml/kg row was transferred from 4:1 Synulox Drops because both contain 40 mg/ml amoxicillin, but Augmentin then supplies only 1.425 mg/kg clavulanate instead of 2.5 mg/kg. No exact-product dog/cat PK, target-animal safety, bioequivalence or clinical bridge was found. Accurate liquid measurement cannot repair an unvalidated component ratio.

The exact human label is transparent, but a product score would hide the missing veterinary bridge. The calculator is intentionally blocked; select an exact dog/cat formulation whose component ratio and regimen are validated.

Important safety and use flags

  • Use only for a diagnosed or strongly supported bacterial infection likely to be susceptible to amoxicillin/clavulanate. Obtain culture and susceptibility whenever feasible and narrow, change or stop treatment when results do not support it.
  • Exact-product boundary: Augmentin 228 mg/5 ml is a 7:1 human suspension, not 4:1 Synulox Drops. Do not transfer the Synulox 0.25 ml/kg regimen by matching amoxicillin concentration alone.
  • No dog or cat calculator dose is published. At the old 0.25 ml/kg volume, this product supplies only 1.425 mg/kg clavulanate rather than the veterinary comparator dose of 2.5 mg/kg; accurate measurement does not validate the altered ratio.
  • Give at the start of a meal to reduce gastrointestinal intolerance. Monitor appetite, vomiting and diarrhoea; severe or persistent signs, haemorrhagic diarrhoea or clinical deterioration require prompt reassessment.
  • Do not use with known penicillin, cephalosporin or other beta-lactam hypersensitivity. Urticaria, facial swelling, dyspnoea, hypotension or collapse may indicate anaphylaxis and requires immediate treatment.
  • Do not assume clavulanate is needed whenever amoxicillin is selected. Use amoxicillin alone when beta-lactamase inhibition is not clinically justified, and avoid unnecessary broad-spectrum or prolonged exposure.
  • Review concurrent bacteriostatic antimicrobials and other medication before treatment. Tetracyclines, macrolides, chloramphenicol, sulfonamides and related combinations require a specific microbiologic and clinical rationale.
  • Renal impairment may require interval or regimen review. Avoid extrapolation in severe hepatic disease, dehydration or unstable patients; monitor clinical response and relevant renal, hepatic or haematologic variables when risk or duration warrants.
  • Reconstitute exactly as the label directs, shake before every dose, refrigerate at 2–8 C, do not freeze and discard after seven days. These handling instructions do not establish a veterinary dose.
  • Pregnancy, lactation, breeding and immature-patient use require explicit veterinarian benefit-risk review. Exact-product target-animal reproductive and developmental safety data are absent.
Assessment sources
  1. Augmentin 228 suspension2024
  2. Augmentin 228 NPRA2026
  3. Augmentin 625 tablets2024
  4. Augmentin 625 SmPC2026
  5. Synulox tablets2025
  6. Synulox drops2025
  7. Clavaseptin PAR2026
  8. ISCAID pyoderma 20252025
  9. ISCAID UTI2019
Assessed: 22 Oct 2026No axis or overall score is shown when the available evidence does not support a responsible numerical assessment.
Cat Proposed oral treatment of a susceptible bacterial infection with exact Augmentin 228 mg/5 ml, a 7:1 human suspension without a validated dog/cat dose bridge
Not rateable
No numerical score assigned
vetman assessment

Augmentin

228 mg/5 ml, powder for oral suspension, human medicine
Assessed clinical scopeCat · Proposed oral treatment of a susceptible bacterial infection with exact Augmentin 228 mg/5 ml, a 7:1 human suspension without a validated dog/cat dose bridge · By mouth
Care settingVeterinarian-directed antimicrobial selection after diagnosis, susceptibility and exact presentation review
vetman score Not rateable No numerical score assigned
Evidence confidence: Medium Georgia: Yes, human · № რ-043538 · Verified on 15 Oct 2026 Off-label use
Not rateable

A numerical score cannot responsibly be assigned to this exact 7:1 suspension in dogs or cats. The prior 0.25 ml/kg row was transferred from 4:1 Synulox Drops because both contain 40 mg/ml amoxicillin, but Augmentin then supplies only 1.425 mg/kg clavulanate instead of 2.5 mg/kg. No exact-product dog/cat PK, target-animal safety, bioequivalence or clinical bridge was found. Accurate liquid measurement cannot repair an unvalidated component ratio.

The exact human label is transparent, but a product score would hide the missing veterinary bridge. The calculator is intentionally blocked; select an exact dog/cat formulation whose component ratio and regimen are validated.

Important safety and use flags

  • Use only for a diagnosed or strongly supported bacterial infection likely to be susceptible to amoxicillin/clavulanate. Obtain culture and susceptibility whenever feasible and narrow, change or stop treatment when results do not support it.
  • Exact-product boundary: Augmentin 228 mg/5 ml is a 7:1 human suspension, not 4:1 Synulox Drops. Do not transfer the Synulox 0.25 ml/kg regimen by matching amoxicillin concentration alone.
  • No dog or cat calculator dose is published. At the old 0.25 ml/kg volume, this product supplies only 1.425 mg/kg clavulanate rather than the veterinary comparator dose of 2.5 mg/kg; accurate measurement does not validate the altered ratio.
  • Give at the start of a meal to reduce gastrointestinal intolerance. Monitor appetite, vomiting and diarrhoea; severe or persistent signs, haemorrhagic diarrhoea or clinical deterioration require prompt reassessment.
  • Do not use with known penicillin, cephalosporin or other beta-lactam hypersensitivity. Urticaria, facial swelling, dyspnoea, hypotension or collapse may indicate anaphylaxis and requires immediate treatment.
  • Do not assume clavulanate is needed whenever amoxicillin is selected. Use amoxicillin alone when beta-lactamase inhibition is not clinically justified, and avoid unnecessary broad-spectrum or prolonged exposure.
  • Review concurrent bacteriostatic antimicrobials and other medication before treatment. Tetracyclines, macrolides, chloramphenicol, sulfonamides and related combinations require a specific microbiologic and clinical rationale.
  • Renal impairment may require interval or regimen review. Avoid extrapolation in severe hepatic disease, dehydration or unstable patients; monitor clinical response and relevant renal, hepatic or haematologic variables when risk or duration warrants.
  • Reconstitute exactly as the label directs, shake before every dose, refrigerate at 2–8 C, do not freeze and discard after seven days. These handling instructions do not establish a veterinary dose.
  • Pregnancy, lactation, breeding and immature-patient use require explicit veterinarian benefit-risk review. Exact-product target-animal reproductive and developmental safety data are absent.
Assessment sources
  1. Augmentin 228 suspension2024
  2. Augmentin 228 NPRA2026
  3. Augmentin 625 tablets2024
  4. Augmentin 625 SmPC2026
  5. Synulox tablets2025
  6. Synulox drops2025
  7. Clavaseptin PAR2026
  8. Feline antimicrobial consensus2025
  9. ISCAID UTI2019
Assessed: 22 Oct 2026No axis or overall score is shown when the available evidence does not support a responsible numerical assessment.
Composition / strength
Amoxicillin40 mg/ml Clavulanic Acid5.7 mg/ml
Formulation Type
Powder
Administration route
By mouth
Manufacturer
GlaxoSmithKline · United Kingdom
Registration
Georgia Yes, human
In force until 08 Jul 2030
Human (Ministry of Health, RAMA)
№ რ-043538
Verified on: 15 Oct 2026
 EU Yes, human
Verified on: 16 Oct 2026
 UK Yes, human
№ PL000380270, PL000380298, PL000380337, PL000380362
Verified on: 16 Oct 2026
 US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified No dog or cat dose is published for this exact 7:1 suspension. Do not transfer the 0.25 ml/kg Synulox Drops regimen: at that volume this product supplies 10 mg/kg amoxicillin but only 1.425 mg/kg clavulanate, versus 2.5 mg/kg in the authorised 4:1 veterinary liquid.

Augmentin 625 mg, Tablet

tablet, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Veterinarian-directed treatment of an appropriate susceptible bacterial infection in a dog whose indication-specific calculated regimen reasonably matches a whole 500/125 mg tablet
6.9/10
Situational / acceptable
vetman assessment

Augmentin

625 mg, tablet, human medicine
Assessed clinical scopeDog · Veterinarian-directed treatment of an appropriate susceptible bacterial infection in a dog whose indication-specific calculated regimen reasonably matches a whole 500/125 mg tablet · By mouth
Care settingVeterinarian-directed outpatient or inpatient antimicrobial treatment with diagnosis, susceptibility, weight and whole-unit fit reviewed
vetman score 6.9/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, human · № რ-043404 · Verified on 15 Oct 2026 Off-label use

A defensible extra-label option only for an appropriate susceptible infection in a dog whose calculated regimen matches a whole tablet. Exact identity and the 4:1 ratio are strengths; absent canine product data, antimicrobial-stewardship limits and poor dose-unit flexibility keep it situational.

Regulatory and scientific credibility7.5/10

The exact 500/125 mg human product has current manufacturer and regulator-aligned prescribing information with composition, contraindications, interactions and subdivision limits. Current authorised veterinary 4:1 comparators verify the dog formulation concept and regimen, but Augmentin itself is not dog-labelled and exact-product canine outcome or bioequivalence data are absent.

Clinical efficacy7.5/10

Amoxicillin/clavulanate has direct authorised dog indications and controlled veterinary comparator trials, with guideline support for selected susceptible infections. Benefit is diagnosis- and susceptibility-dependent; broad empirical use, transfer of every human indication, or clavulanate where amoxicillin alone suffices is not supported.

Safety and tolerability7.0/10

The beta-lactam combination is generally well tolerated but can cause gastrointestinal effects, hypersensitivity including anaphylaxis, microbiome disruption and selection pressure. Renal impairment, pregnancy/lactation, interacting antimicrobials and previous beta-lactam reactions require review; exact-product canine safety and fragment uniformity are untested.

Clinical practicality5.0/10

Twice-daily oral dosing is familiar, but the 500/125 mg unit fits only selected large dogs and indication-specific dose points. The score line is not an equal-dose divider, so the old half-tablet band is removed; smaller dogs require another validated strength or formulation.

Full-course cost-effectiveness-

Current comparable full-course local prices were not verified.

Important safety and use flags

  • Use only for a diagnosed or strongly supported bacterial infection likely to be susceptible to amoxicillin/clavulanate. Obtain culture and susceptibility whenever feasible and narrow, change or stop treatment when results do not support it.
  • Exact-product boundary: each tablet is 500 mg amoxicillin plus 125 mg clavulanate. Do not substitute a different co-amoxiclav strength by matching only the amoxicillin number; component ratios and delivered clavulanate may differ.
  • Use only a whole tablet when the indication-specific calculated regimen fits. The line is for ease of swallowing, not equal-dose subdivision; do not restore the old half-tablet band or improvise smaller fragments.
  • Give at the start of a meal to reduce gastrointestinal intolerance. Monitor appetite, vomiting and diarrhoea; severe or persistent signs, haemorrhagic diarrhoea or clinical deterioration require prompt reassessment.
  • Do not use with known penicillin, cephalosporin or other beta-lactam hypersensitivity. Urticaria, facial swelling, dyspnoea, hypotension or collapse may indicate anaphylaxis and requires immediate treatment.
  • Do not assume clavulanate is needed whenever amoxicillin is selected. Use amoxicillin alone when beta-lactamase inhibition is not clinically justified, and avoid unnecessary broad-spectrum or prolonged exposure.
  • Review concurrent bacteriostatic antimicrobials and other medication before treatment. Tetracyclines, macrolides, chloramphenicol, sulfonamides and related combinations require a specific microbiologic and clinical rationale.
  • Renal impairment may require interval or regimen review. Avoid extrapolation in severe hepatic disease, dehydration or unstable patients; monitor clinical response and relevant renal, hepatic or haematologic variables when risk or duration warrants.
  • Do not crush or pre-divide for dose measurement. Confirm that the dog can safely swallow the whole unit and use another validated strength or formulation when it cannot.
  • Pregnancy, lactation, breeding and immature-patient use require explicit veterinarian benefit-risk review. Exact-product target-animal reproductive and developmental safety data are absent.
Assessment sources
  1. Augmentin 228 suspension2024
  2. Augmentin 228 NPRA2026
  3. Augmentin 625 tablets2024
  4. Augmentin 625 SmPC2026
  5. Synulox tablets2025
  6. Synulox drops2025
  7. Clavaseptin PAR2026
  8. ISCAID pyoderma 20252025
  9. ISCAID UTI2019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Proposed oral treatment of a susceptible feline bacterial infection with exact Augmentin 625 mg, an indivisible 500/125 mg human dose unit
Not rateable
No numerical score assigned
vetman assessment

Augmentin

625 mg, tablet, human medicine
Assessed clinical scopeCat · Proposed oral treatment of a susceptible feline bacterial infection with exact Augmentin 625 mg, an indivisible 500/125 mg human dose unit · By mouth
Care settingVeterinarian-directed antimicrobial selection after diagnosis, susceptibility and exact presentation review
vetman score Not rateable No numerical score assigned
Evidence confidence: Medium Georgia: Yes, human · № რ-043404 · Verified on 15 Oct 2026 Off-label use
Not rateable

A numerical feline score cannot responsibly be assigned. The exact 625 mg tablet supplies 500/125 mg and the current SmPC says its line is only to ease swallowing, not to obtain equal doses. A whole tablet is not a credible typical feline unit, while a half or smaller piece would invent an unvalidated delivered dose. Strong class evidence does not make this presentation doseable in cats.

The active combination is established in cats, but this exact large human tablet is not. Prefer a veterinary strength or liquid that can deliver the calculated component doses without relying on unequal fragments.

Important safety and use flags

  • Use only for a diagnosed or strongly supported bacterial infection likely to be susceptible to amoxicillin/clavulanate. Obtain culture and susceptibility whenever feasible and narrow, change or stop treatment when results do not support it.
  • Exact-product boundary: each tablet is 500 mg amoxicillin plus 125 mg clavulanate. Do not substitute a different co-amoxiclav strength by matching only the amoxicillin number; component ratios and delivered clavulanate may differ.
  • No feline calculator dose is published. A whole 500/125 mg tablet is not a credible typical feline unit, and the exact label does not validate a half or smaller equal dose.
  • Give at the start of a meal to reduce gastrointestinal intolerance. Monitor appetite, vomiting and diarrhoea; severe or persistent signs, haemorrhagic diarrhoea or clinical deterioration require prompt reassessment.
  • Do not use with known penicillin, cephalosporin or other beta-lactam hypersensitivity. Urticaria, facial swelling, dyspnoea, hypotension or collapse may indicate anaphylaxis and requires immediate treatment.
  • Do not assume clavulanate is needed whenever amoxicillin is selected. Use amoxicillin alone when beta-lactamase inhibition is not clinically justified, and avoid unnecessary broad-spectrum or prolonged exposure.
  • Review concurrent bacteriostatic antimicrobials and other medication before treatment. Tetracyclines, macrolides, chloramphenicol, sulfonamides and related combinations require a specific microbiologic and clinical rationale.
  • Renal impairment may require interval or regimen review. Avoid extrapolation in severe hepatic disease, dehydration or unstable patients; monitor clinical response and relevant renal, hepatic or haematologic variables when risk or duration warrants.
  • Do not crush or pre-divide for dose measurement. Confirm that the dog can safely swallow the whole unit and use another validated strength or formulation when it cannot.
  • Pregnancy, lactation, breeding and immature-patient use require explicit veterinarian benefit-risk review. Exact-product target-animal reproductive and developmental safety data are absent.
Assessment sources
  1. Augmentin 228 suspension2024
  2. Augmentin 228 NPRA2026
  3. Augmentin 625 tablets2024
  4. Augmentin 625 SmPC2026
  5. Synulox tablets2025
  6. Synulox drops2025
  7. Clavaseptin PAR2026
  8. Feline antimicrobial consensus2025
  9. ISCAID UTI2019
Assessed: 22 Oct 2026No axis or overall score is shown when the available evidence does not support a responsible numerical assessment.
Composition / strength
Amoxicillin500 mg Clavulanic Acid125 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
GlaxoSmithKline · United Kingdom
Registration
Georgia Yes, human
In force until 12 Jun 2030
Human (Ministry of Health, RAMA)
№ რ-043404
Verified on: 15 Oct 2026
 EU Yes, human
Verified on: 16 Oct 2026
 UK Yes, human
№ PL000380270, PL000380298, PL000380337, PL000380362
Verified on: 16 Oct 2026
 US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified One tablet contains 500 mg amoxicillin plus 125 mg clavulanate. The line may ease swallowing but is not validated to divide the tablet into equal doses. Only whole-unit use can be considered, and only when the calculated indication-specific regimen fits.

Aurobindo Amoxicillin/Clavulanate 62.5 mg/ml oral suspension, Suspension

15 ml for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label transferred from Clavamox Drops: susceptible skin, soft-tissue and periodontal bacterial infections treated with 62.5 mg/ml oral suspension
6.8/10
Situational / acceptable
vetman assessment

Aurobindo Amoxicillin/Clavulanate

62.5 mg/ml oral suspension, 15 ml for dogs and cats
Assessed clinical scopeDog · Full dog label transferred from Clavamox Drops: susceptible skin, soft-tissue and periodontal bacterial infections treated with 62.5 mg/ml oral suspension · By mouth
Care settingOutpatient antimicrobial treatment after diagnosis, with comparator-derived dosing and the unresolved exact-pack conflict visible
vetman score 6.8/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 287-11 · Verified on 21 Oct 2026

The pharmacology is credible, but this exact presentation is only situationally acceptable until its 15-versus-30 ml identity conflict and exact instructions are resolved. Verify the physical pack and manufacturer leaflet before prescribing.

Regulatory and scientific credibility5.5/10

The exact Aurobindo product is actively registered in Georgia, but its bilingual register row conflicts on 30 ml versus 15 ml and no exact public SPC was found; the clinical instructions come from Clavamox Drops, not this manufacturer.

Clinical efficacy7.5/10

Amoxicillin/clavulanate suspension is established for susceptible canine skin, soft-tissue and periodontal infections, but exact-product efficacy is indirect and treatment must follow diagnosis and susceptibility.

Safety and tolerability7.5/10

Class and comparator safety are established, but exact-product and reproductive safety documentation are limited; gastrointestinal reactions and beta-lactam allergy remain central.

Clinical practicality6.5/10

Liquid dosing can suit small dogs, but exact reconstitution, vigorous shaking, refrigeration, ten-day discard and the unresolved bottle-volume conflict materially increase error and waste risk.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after penicillin or cephalosporin hypersensitivity; serious cross-reactions are possible.
  • The Georgian register conflicts on a 30 ml versus 15 ml bottle and no exact Aurobindo SPC is public; verify the physical product before use.
  • The displayed reconstitution and dose come from Clavamox Drops, not an exact Aurobindo instruction; do not transfer them without pack verification.
  • Treat only a diagnosed susceptible bacterial infection; use culture and susceptibility testing whenever feasible.
  • Comparator handling requires exact water addition, vigorous shaking, refrigeration and disposal after 10 days.
  • Safety in pregnant or breeding animals is not established in the comparator label.
  • Monitor anorexia, lethargy, vomiting, diarrhoea and allergic reactions; reassess inadequate response rather than extending empirically.
Assessment sources
  1. FDA NADA 055-1012019
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label transferred from Clavamox Drops: susceptible skin, soft-tissue and urinary bacterial infections treated with 62.5 mg/ml oral suspension
6.9/10
Situational / acceptable
vetman assessment

Aurobindo Amoxicillin/Clavulanate

62.5 mg/ml oral suspension, 15 ml for dogs and cats
Assessed clinical scopeCat · Full cat label transferred from Clavamox Drops: susceptible skin, soft-tissue and urinary bacterial infections treated with 62.5 mg/ml oral suspension · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with comparator-derived dosing and the unresolved exact-pack conflict visible
vetman score 6.9/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 287-11 · Verified on 21 Oct 2026

The fixed feline dose is convenient, but this exact presentation remains situational until the 15-versus-30 ml identity conflict and exact manufacturer instructions are resolved. Confirm bacterial disease and verify the physical pack.

Regulatory and scientific credibility5.5/10

The exact Aurobindo product is actively registered in Georgia, but its bilingual register row conflicts on 30 ml versus 15 ml and no exact public SPC was found; the clinical instructions come from Clavamox Drops.

Clinical efficacy7.5/10

The class is established for susceptible feline skin, soft-tissue and urinary infections, but most young cats with lower urinary signs are not bacterially infected and exact-product efficacy evidence is indirect.

Safety and tolerability7.5/10

Class and comparator safety are established, but exact-product and reproductive safety documentation are limited; gastrointestinal reactions and beta-lactam allergy remain central.

Clinical practicality7.0/10

A fixed 1 ml feline dose is simple, but exact reconstitution, vigorous shaking, refrigeration, ten-day discard and the unresolved bottle-volume conflict add substantial handling risk.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after penicillin or cephalosporin hypersensitivity; serious cross-reactions are possible.
  • The Georgian register conflicts on a 30 ml versus 15 ml bottle and no exact Aurobindo SPC is public; verify the physical product before use.
  • The displayed reconstitution and dose come from Clavamox Drops, not an exact Aurobindo instruction; do not transfer them without pack verification.
  • Treat only a diagnosed susceptible bacterial infection; use culture and susceptibility testing whenever feasible.
  • Comparator handling requires exact water addition, vigorous shaking, refrigeration and disposal after 10 days.
  • Safety in pregnant or breeding animals is not established in the comparator label.
  • Monitor anorexia, lethargy, vomiting, diarrhoea and allergic reactions; reassess inadequate response rather than extending empirically.
Assessment sources
  1. FDA NADA 055-1012019
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin50 mg/ml Clavulanic Acid12.5 mg/ml
Formulation Type
Suspension
Administration route
oral
Manufacturer
Aurobindo Pharma Limited · India
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ამოქსიცილინის და კალიუმის კლავულანატის პერორალური წვეთების მოსამზადებელი სუსპენზიისთვის 62.5მგ
№ 287-11
Verified on: 21 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Aurobindo Amoxicillin/Clavulanate 62.5 mg veterinary tablets, Coated tablet

210 tablets for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label transferred from the same-strength FDA reference generic: susceptible skin, soft-tissue and periodontal bacterial infections treated with 62.5 mg amoxicillin/clavulanate tablets
7.1/10
Good
vetman assessment

Aurobindo Amoxicillin/Clavulanate

62.5 mg veterinary tablets, 210 tablets for dogs and cats
Assessed clinical scopeDog · Full dog label transferred from the same-strength FDA reference generic: susceptible skin, soft-tissue and periodontal bacterial infections treated with 62.5 mg amoxicillin/clavulanate tablets · By mouth
Care settingOutpatient antimicrobial treatment after diagnosis; culture and susceptibility testing whenever feasible, with comparator-derived clinical claims kept explicit
vetman score 7.1/10 Good
Evidence confidence: Low Georgia: Yes, veterinary · № 286-11 · Verified on 21 Oct 2026

A doseable same-strength generic comparator supports cautious use near whole-tablet weight steps, but exact-product clinical transparency is limited. Culture, narrow-spectrum selection and whole-tablet accuracy are essential.

Regulatory and scientific credibility6.5/10

The exact Aurobindo product is actively registered in Georgia, but no exact public SPC or dossier was found; clinical details rely on a same-strength FDA generic comparator and the Georgian pack description contains ordering defects.

Clinical efficacy7.5/10

The class is effective for susceptible canine skin, soft-tissue and periodontal infections, with bioequivalence evidence for the comparator generic; applicability to this exact Aurobindo presentation is indirect and susceptibility remains decisive.

Safety and tolerability7.5/10

Class safety is established, with gastrointestinal reactions and beta-lactam hypersensitivity as key risks; exact-product and reproductive safety documentation are limited.

Clinical practicality6.5/10

One whole unscored tablet per 4.54 kg every 12 hours is workable only near the printed weight steps; do not split it to create an unvalidated intermediate dose.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after penicillin or cephalosporin hypersensitivity; serious cross-reactions are possible.
  • The public clinical label is from a same-strength FDA-approved comparator, not an exact Aurobindo SPC; verify the physical pack and leaflet.
  • Treat only a diagnosed susceptible bacterial infection; use culture and susceptibility testing whenever feasible.
  • Use the whole unscored tablet at the printed weight step; do not split it to create an unvalidated dose.
  • Safety in pregnant or breeding animals is not established in the comparator label.
  • Monitor anorexia, lethargy, vomiting, diarrhoea and allergic reactions; report significant adverse events.
  • Prefer the narrowest effective antimicrobial and reassess diagnosis, source control and susceptibility if response is inadequate.
Assessment sources
  1. FDA ANADA 200-7022024
  2. FDA ANADA 200-702 FOI2021
  3. Georgia NFA register 20262026
  4. ISCAID 20252025
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label transferred from the same-strength FDA reference generic: susceptible skin, soft-tissue and urinary bacterial infections treated with one 62.5 mg amoxicillin/clavulanate tablet every 12 hours
7.2/10
Good
vetman assessment

Aurobindo Amoxicillin/Clavulanate

62.5 mg veterinary tablets, 210 tablets for dogs and cats
Assessed clinical scopeCat · Full cat label transferred from the same-strength FDA reference generic: susceptible skin, soft-tissue and urinary bacterial infections treated with one 62.5 mg amoxicillin/clavulanate tablet every 12 hours · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible and comparator-derived claims explicit
vetman score 7.2/10 Good
Evidence confidence: Low Georgia: Yes, veterinary · № 286-11 · Verified on 21 Oct 2026

The fixed feline dose is practical when bacterial infection is confirmed, but exact-product transparency is limited and comparator evidence is not exact-product proof. Avoid treating non-bacterial feline lower urinary disease.

Regulatory and scientific credibility6.5/10

The exact Aurobindo product is actively registered in Georgia, but no exact public SPC or dossier was found; the feline label is transferred from a same-strength FDA generic comparator.

Clinical efficacy7.5/10

The class is established for susceptible feline skin, soft-tissue and urinary infections, but most young cats with lower urinary signs are not bacterially infected; exact-product efficacy evidence is indirect.

Safety and tolerability7.5/10

Class safety is established, with gastrointestinal reactions and beta-lactam hypersensitivity as key risks; exact-product and reproductive safety documentation are limited.

Clinical practicality7.5/10

The label-derived feline regimen is a simple fixed one-tablet dose every 12 hours, but the tablet is unscored and repeated home dosing still requires reliable adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after penicillin or cephalosporin hypersensitivity; serious cross-reactions are possible.
  • The public clinical label is from a same-strength FDA-approved comparator, not an exact Aurobindo SPC; verify the physical pack and leaflet.
  • Treat only a diagnosed susceptible bacterial infection; use culture and susceptibility testing whenever feasible.
  • Use the whole unscored tablet at the printed weight step; do not split it to create an unvalidated dose.
  • Safety in pregnant or breeding animals is not established in the comparator label.
  • Monitor anorexia, lethargy, vomiting, diarrhoea and allergic reactions; report significant adverse events.
  • Prefer the narrowest effective antimicrobial and reassess diagnosis, source control and susceptibility if response is inadequate.
Assessment sources
  1. FDA ANADA 200-7022024
  2. FDA ANADA 200-702 FOI2021
  3. Georgia NFA register 20262026
  4. ISCAID 20252025
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin50 mg Clavulanic Acid12.5 mg
Formulation Type
Coated tablet
Administration route
oral
Manufacturer
Aurobindo Pharma Limited · India
Manufacturer (register)
AUROBINDO PHARMA LIMITED, India
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 733, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: მოქსიცილინის და კალიუმის კლავულანატის ტაბლეტები 62.5მგ
№ 286-11
Verified on: 21 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Aurobindo Amoxicillin/Clavulanate 375 mg veterinary tablets, Coated tablet

210 tablets for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.0/10
Good
vetman assessment

Aurobindo Amoxicillin/Clavulanate

375 mg veterinary tablets, 210 tablets for dogs
Assessed clinical scopeDog · Full dog label transferred from the same-strength FDA reference generic: susceptible skin, soft-tissue and periodontal bacterial infections treated with 375 mg amoxicillin/clavulanate tablets · By mouth
Care settingOutpatient antimicrobial treatment after diagnosis; culture and susceptibility testing whenever feasible, with explicit recognition that the clinical label is comparator-derived
vetman score 7.0/10 Good
Evidence confidence: Low Georgia: Yes, veterinary · № 240-11 · Verified on 21 Oct 2026

A plausible same-strength generic option, but the rating is deliberately restrained because the exact product lacks a public clinical SPC and the unscored 27.22 kg dose step is coarse. Do not treat comparator evidence as exact-product proof.

Regulatory and scientific credibility6.5/10

The exact Aurobindo product is actively registered in Georgia, but no exact public SPC or dossier was found; the dose and clinical scope rely on a same-strength FDA-approved generic comparator, while the Georgian register has a pack-description defect.

Clinical efficacy7.5/10

The class is effective for susceptible canine skin, soft-tissue and periodontal infections, and the comparator generic is bioequivalent to Clavamox; efficacy is indirect for this exact Aurobindo presentation and resistance still limits empirical use.

Safety and tolerability7.5/10

Class and comparator safety are well characterised, with gastrointestinal reactions and beta-lactam hypersensitivity as key concerns, but exact-product safety documentation and reproductive safety are limited.

Clinical practicality6.0/10

One unscored tablet per 27.22 kg every 12 hours creates poor dose granularity for many dogs; the tablet should not be split to manufacture an unvalidated intermediate dose.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after penicillin or cephalosporin hypersensitivity; serious cross-reactions are possible.
  • The public clinical label is from a same-strength FDA-approved comparator, not an exact Aurobindo SPC; verify the physical pack and leaflet.
  • Treat only a diagnosed susceptible bacterial infection; use culture and susceptibility testing whenever feasible.
  • Use the whole unscored tablet at the printed weight step; do not split it to create an unvalidated dose.
  • Safety in pregnant or breeding animals is not established in the comparator label.
  • Monitor anorexia, lethargy, vomiting, diarrhoea and allergic reactions; report significant adverse events.
  • Prefer the narrowest effective antimicrobial and reassess diagnosis, source control and susceptibility if response is inadequate.
Assessment sources
  1. FDA ANADA 200-7022024
  2. FDA ANADA 200-702 FOI2021
  3. Georgia NFA register 20262026
  4. ISCAID 20252025
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin300 mg Clavulanic Acid75 mg
Formulation Type
Coated tablet
Administration route
oral
Manufacturer
Aurobindo Pharma Limited · India
Manufacturer (register)
AUROBINDO PHARMA LIMITED, India
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 702, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ამოქსიცილინის და კალიუმის კლავულანატის ტაბლეტები 375მგ
№ 240-11
Verified on: 21 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Cladaxxa 40 mg/10 mg, Scored tablet

amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg
8.3/10
Very good
vetman assessment

Cladaxxa

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.3/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 255-11 · Verified on 19 Oct 2026

A strong small-dog amoxicillin/clavulanate presentation with exact regulatory support and practical dose bands. Its broad spectrum is valuable only when susceptibility and syndrome justify clavulanate.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible presentation is actively registered in Georgia and has a current detailed UK SPC covering indications, dose bands, resistance safeguards, safety and course duration.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label and supported by current syndrome guidance. Benefit depends on susceptibility and source control; it does not cover Pseudomonas or MRSP and should not replace a narrower effective drug.

Safety and tolerability7.8/10

The expected profile is generally favourable; vomiting, diarrhoea, anorexia and allergy remain relevant, with strict avoidance in beta-lactam hypersensitivity and severe oliguric or anuric renal impairment.

Clinical practicality8.2/10

A palatable half-divisible tablet, clear 2-10 kg bands and direct-or-food administration make dosing practical; twice-daily courses and longer chronic-infection regimens still require reliable home adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg
8.3/10
Very good
vetman assessment

Cladaxxa

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.3/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 255-11 · Verified on 19 Oct 2026

A practical, exactly documented small-cat presentation for confirmed susceptible bacterial disease. It should not be used as a default response to feline lower urinary or respiratory signs without evidence of bacterial infection.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible presentation is actively registered in Georgia and has a current detailed UK SPC with feline indications, dose bands, resistance safeguards and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible feline infections, but feline urinary and respiratory signs are often non-bacterial. It does not cover Pseudomonas or MRSP and should follow diagnosis, culture when feasible and narrow-spectrum selection.

Safety and tolerability7.8/10

The expected profile is generally favourable; gastrointestinal signs and allergy remain relevant, with strict avoidance in beta-lactam hypersensitivity and severe oliguric or anuric renal impairment.

Clinical practicality8.2/10

The small palatable half-divisible tablet maps well to common feline weights and can be given directly or in a little food; twice-daily dosing and accurate halves still require adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin40 mg Clavulanic Acid10 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1178, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Cladaxxa 200 mg/50 mg, Scored tablet

amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg
8.2/10
Very good
vetman assessment

Cladaxxa

200 mg/50 mg, amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 257-11 · Verified on 19 Oct 2026

A well-supported medium-dog strength with exact half-tablet bands and broad susceptible-infection utility. Stewardship, source control and reassessment remain essential despite the convenient presentation.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible 200/50 mg presentation is actively registered in Georgia and has a current detailed UK SPC with complete dose, resistance and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label, but response depends on susceptibility and source control; it does not cover Pseudomonas or MRSP and is not justified when a narrower drug works.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe renal impairment with anuria or oliguria are contraindications.

Clinical practicality8.1/10

Half-tablet 8-10 kg and whole-tablet 10-20 kg bands make this strength practical for medium dogs; twice-daily administration and longer selected courses remain an adherence burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg
8.0/10
Very good
vetman assessment

Cladaxxa

200 mg/50 mg, amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 257-11 · Verified on 19 Oct 2026

The medicine is clinically sound when susceptibility supports it, but this exact 200/50 mg presentation is a poor practical match for most cats. The score must not imply interchangeability with the smaller feline strength.

Regulatory and scientific credibility9.0/10

The exact presentation is actively registered in Georgia and has a current detailed UK SPC that includes cats, but the strength is only doseable from above 8 kg in the printed half-tablet bands.

Clinical efficacy8.0/10

The active combination is established for susceptible feline infections, but bacterial disease must first be confirmed and the drug does not cover Pseudomonas or MRSP; broad empirical use is poor stewardship.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe oliguric or anuric renal impairment are contraindications.

Clinical practicality6.8/10

The tablet is half-divisible but its first printed feline band is above 8-10 kg, so it is unsuitable for most cats; the 40/10 mg presentation is materially more doseable for typical feline weights.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin200 mg Clavulanic Acid50 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1180, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Cladaxxa 400 mg/100 mg, Scored tablet

amoxicillin 400 mg + clavulanic acid 100 mg, divisible chewable tablet for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.2/10
Very good
vetman assessment

Cladaxxa

400 mg/100 mg, amoxicillin 400 mg + clavulanic acid 100 mg, divisible chewable tablet for dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 400/100 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 256-11 · Verified on 19 Oct 2026

A well-documented large-dog strength with practical half-tablet bands and broad susceptible-infection utility. Culture, source control and the narrowest effective antimicrobial remain decisive.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible 400/100 mg presentation is actively registered in Georgia and has a current detailed UK SPC with complete large-dog dose bands and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label, but efficacy depends on diagnosis, susceptibility and source control; Pseudomonas and MRSP are not covered and narrower therapy is preferred when adequate.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe renal impairment with anuria or oliguria are contraindications.

Clinical practicality8.1/10

Half-tablet 10-20 kg through two-tablet 60-80 kg bands make this strength practical for larger dogs; twice-daily administration and longer selected courses still require adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin400 mg Clavulanic Acid100 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1179, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Nicilan 40 mg/10 mg, Scored tablet

amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate
8.0/10
Very good
vetman assessment

Nicilan

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 267-11 · Verified on 19 Oct 2026

A well-documented broad oral antibiotic for genuinely susceptible canine infections. Its score assumes diagnosis-led, narrowest-effective prescribing and falls if it is used empirically for non-bacterial disease or where amoxicillin alone would suffice.

Regulatory and scientific credibility8.7/10

The exact divisible 40/10 mg product is actively registered in Georgia and has a current transparent EU regulator SPC; independent evidence is mainly at ingredient/class and syndrome-guideline level.

Clinical efficacy7.8/10

Amoxicillin/clavulanate is an established option for confirmed susceptible infections across the broad label, but efficacy depends on diagnosis and local susceptibility; it is not active against Pseudomonas or methicillin-resistant staphylococci and is often broader than necessary.

Safety and tolerability7.8/10

The therapeutic margin is generally favourable, but gastrointestinal reactions and uncommon hypersensitivity occur; beta-lactam allergy and severe renal impairment with anuria or oliguria are hard stops, and resistance selection matters.

Clinical practicality7.5/10

Twice-daily home dosing and a usual 5-7-day course are workable; the divisible tablet supports weight bands, but repeated administration, longer chronic courses and dose escalation only after reassessment add adherence and prescribing burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. EU SPC 20252025
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate
8.0/10
Very good
vetman assessment

Nicilan

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 267-11 · Verified on 19 Oct 2026

A well-supported oral option for confirmed susceptible feline bacterial disease, not a default treatment for undifferentiated respiratory, intestinal or lower urinary signs. Culture and the narrowest effective agent remain central.

Regulatory and scientific credibility8.7/10

The exact divisible 40/10 mg product is actively registered in Georgia and has a current transparent EU regulator SPC; independent evidence is mainly class-level and syndrome-specific guidance.

Clinical efficacy7.8/10

The combination is useful for confirmed susceptible feline infections, but most young cats with lower urinary signs do not have bacterial cystitis, susceptibility varies, and the drug does not cover Pseudomonas or methicillin-resistant staphylococci.

Safety and tolerability7.8/10

The therapeutic margin is generally favourable, but gastrointestinal reactions and uncommon hypersensitivity occur; beta-lactam allergy and severe renal impairment with anuria or oliguria are hard stops.

Clinical practicality7.5/10

The small divisible tablet fits common feline weight bands, but twice-daily home dosing, accurate half-tablet use and longer selected courses still require adherence and reassessment.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. EU SPC 20252025
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin40 mg Clavulanic Acid10 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
Laboratorios Calier S.A. · Spain
Manufacturer (register)
LABORATORIOS CALIER, S.A, Spain
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1501, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ნიცილანი 40 მგ/10 მგ
№ 267-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Synuxol-Nita 50 mg tablets N10 for dogs and cats, Tablet

vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: infections caused by amoxicillin-clavulanate-susceptible bacteria, 12.5 mg/kg combined twice daily by a quarter-tablet table for 0.5-5 kg
6.4/10
Situational / acceptable
vetman assessment

Synuxol-Nita

50 mg tablets N10 for dogs and cats
Assessed clinical scopeDog · Full dog label: infections caused by amoxicillin-clavulanate-susceptible bacteria, 12.5 mg/kg combined twice daily by a quarter-tablet table for 0.5-5 kg · oral
Care settingVeterinary prescription after diagnosis for oral treatment at home, with culture for recurrent or complicated infection
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 000915 · Verified on 21 Oct 2026

A situational, reasonable first-line antimicrobial for small dogs: the composition and dose follow established amoxicillin-clavulanate practice. Its weaknesses are the local-only registration and the lack of bioequivalence data.

Regulatory and scientific credibility5.0/10

The exact product is registered in Georgia (000915, valid to 2030) with a current NITA-FARM instruction; it has no EU, UK or US authorisation documented in the reviewed evidence, but its 4:1 composition and 12.5 mg/kg twice-daily dose match long-established authorised amoxicillin-clavulanate products.

Clinical efficacy6.5/10

Amoxicillin-clavulanate has strong independent evidence and is a WSAVA essential medicine and an ISCAID option for many skin, soft-tissue and urinary infections; the bioequivalence of this formulation is unproven.

Safety and tolerability7.5/10

The class is well tolerated; vomiting, diarrhoea and penicillin hypersensitivity are the main risks, and the label asks for benefit-risk assessment in pregnancy and lactation.

Clinical practicality7.0/10

Quarter-tablet steps twice daily suit dogs of 0.5-5 kg; larger dogs need another strength, and clavulanate tablets must be kept dry in the blister.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not use with penicillin or cephalosporin hypersensitivity, and never give to rabbits, guinea pigs, hamsters, gerbils or chinchillas.
  • Amoxicillin-clavulanate is EU AMEG Category C (Caution): plain amoxicillin is usually preferred for sporadic cystitis, and topical therapy alone often suffices for superficial pyoderma.
  • Do not combine with the bacteriostatic antimicrobials listed on the label.
  • Watch for vomiting, diarrhoea or allergic reactions and recheck if signs do not improve within a few days.
  • Dose by the combined 12.5 mg/kg; this 50 mg tablet covers only 0.5-5 kg.
Assessment sources
  1. NITA-FARM Synuxol-Nita
  2. Georgia NFA register 20262026
  3. ISCAID pyoderma 20252025
  4. ISCAID urinary 20192019
  5. WSAVA essential medicines 20232023
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: infections caused by amoxicillin-clavulanate-susceptible bacteria, 12.5 mg/kg combined twice daily by a quarter-tablet table for 0.5-5 kg
6.4/10
Situational / acceptable
vetman assessment

Synuxol-Nita

50 mg tablets N10 for dogs and cats
Assessed clinical scopeCat · Full cat label: infections caused by amoxicillin-clavulanate-susceptible bacteria, 12.5 mg/kg combined twice daily by a quarter-tablet table for 0.5-5 kg · oral
Care settingVeterinary prescription after diagnosis for oral treatment at home, with culture for recurrent or complicated infection
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Low Georgia: Yes, veterinary · № 000915 · Verified on 21 Oct 2026

A situational, reasonable first-line antimicrobial for cats: the composition and dose follow established amoxicillin-clavulanate practice. Its weaknesses are the local-only registration, missing bioequivalence data and twice-daily pilling.

Regulatory and scientific credibility5.0/10

The exact product is registered in Georgia (000915, valid to 2030) with a current NITA-FARM instruction; it has no EU, UK or US authorisation documented in the reviewed evidence, but its 4:1 composition and 12.5 mg/kg twice-daily dose match long-established authorised amoxicillin-clavulanate products.

Clinical efficacy6.5/10

Amoxicillin-clavulanate has strong independent evidence in cats for bite abscesses, skin and urinary infections and is a WSAVA essential medicine; it does not cover Mycoplasma or Chlamydia, and this formulation's bioequivalence is unproven.

Safety and tolerability7.5/10

The class is well tolerated in cats; vomiting, diarrhoea and penicillin hypersensitivity are the main risks, and the label asks for benefit-risk assessment in pregnancy and lactation.

Clinical practicality6.5/10

Quarter-tablet steps fit cats of 0.5-5 kg well, but twice-daily pilling is harder in cats, and the tablets must be kept dry in the blister.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not use with penicillin or cephalosporin hypersensitivity, and never give to rabbits, guinea pigs, hamsters, gerbils or chinchillas.
  • Amoxicillin-clavulanate is EU AMEG Category C (Caution): drain abscesses first, and use plain amoxicillin for sporadic cystitis where possible.
  • It does not treat Mycoplasma or Chlamydia felis; use doxycycline for those respiratory and eye infections.
  • Watch for vomiting, diarrhoea or allergic reactions and recheck if signs do not improve within a few days.
  • Dose by the combined 12.5 mg/kg; do not combine with the bacteriostatic antimicrobials listed on the label.
Assessment sources
  1. NITA-FARM Synuxol-Nita
  2. Georgia NFA register 20262026
  3. Feline antimicrobial consensus2025
  4. ISCAID urinary 20192019
  5. WSAVA essential medicines 20232023
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin40 mg Clavulanic Acid10 mg
Formulation Type
Tablet
Administration route
oral
Manufacturer
NITA-FARM LLC · Russia
Manufacturer (register)
Nita-farm Ltd, Russia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1460, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
In force until 11 Aug 2030
Veterinary (National Food Agency)
In the register: სინუქსოლ-ნიტა®
№ 000915
Verified on: 21 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

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