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Cladaxxa

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Amoxicillin + Clavulanic Acid · KRKA, d.d., Novo mesto

3 forms: scored tablet. In force in Georgia: 3 of 3 (veterinary register).

Forms and doses3 of 3 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
40 mg/10 mg, Scored tablet · Cat up to 2 kg Cat up to 2 kg 1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Cat 2–4 kg Cat 2–4 kg 1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Cat 4–6 kg Cat 4–6 kg 1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Cat 6–8 kg Cat 6–8 kg 2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Cat 8–10 kg Cat 8–10 kg 2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Dog up to 2 kg Dog up to 2 kg 1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Dog 2–4 kg Dog 2–4 kg 1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Dog 4–6 kg Dog 4–6 kg 1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Dog 6–8 kg Dog 6–8 kg 2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
40 mg/10 mg, Scored tablet · Dog 8–10 kg Dog 8–10 kg 2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
Details: pack, label wording, sources, registration

Cladaxxa 40 mg/10 mg, Scored tablet

amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg
8.3/10
Very good
vetman assessment

Cladaxxa

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.3/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 255-11 · Verified on 19 Oct 2026

A strong small-dog amoxicillin/clavulanate presentation with exact regulatory support and practical dose bands. Its broad spectrum is valuable only when susceptibility and syndrome justify clavulanate.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible presentation is actively registered in Georgia and has a current detailed UK SPC covering indications, dose bands, resistance safeguards, safety and course duration.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label and supported by current syndrome guidance. Benefit depends on susceptibility and source control; it does not cover Pseudomonas or MRSP and should not replace a narrower effective drug.

Safety and tolerability7.8/10

The expected profile is generally favourable; vomiting, diarrhoea, anorexia and allergy remain relevant, with strict avoidance in beta-lactam hypersensitivity and severe oliguric or anuric renal impairment.

Clinical practicality8.2/10

A palatable half-divisible tablet, clear 2-10 kg bands and direct-or-food administration make dosing practical; twice-daily courses and longer chronic-infection regimens still require reliable home adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg
8.3/10
Very good
vetman assessment

Cladaxxa

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 40/10 mg · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.3/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 255-11 · Verified on 19 Oct 2026

A practical, exactly documented small-cat presentation for confirmed susceptible bacterial disease. It should not be used as a default response to feline lower urinary or respiratory signs without evidence of bacterial infection.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible presentation is actively registered in Georgia and has a current detailed UK SPC with feline indications, dose bands, resistance safeguards and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible feline infections, but feline urinary and respiratory signs are often non-bacterial. It does not cover Pseudomonas or MRSP and should follow diagnosis, culture when feasible and narrow-spectrum selection.

Safety and tolerability7.8/10

The expected profile is generally favourable; gastrointestinal signs and allergy remain relevant, with strict avoidance in beta-lactam hypersensitivity and severe oliguric or anuric renal impairment.

Clinical practicality8.2/10

The small palatable half-divisible tablet maps well to common feline weights and can be given directly or in a little food; twice-daily dosing and accurate halves still require adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin40 mg Clavulanic Acid10 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1178, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 40 მგ/10 მგ
№ 255-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat up to 2 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 2–4 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 4–6 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 6–8 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 8–10 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog up to 2 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 2–4 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 4–6 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 6–8 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 8–10 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 40 mg/10 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
200 mg/50 mg, Scored tablet · Cat 8–10 kg Cat 8–10 kg 1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Cat 10–20 kg Cat 10–20 kg 1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Cat 20–30 kg Cat 20–30 kg 1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Cat 30–40 kg Cat 30–40 kg 2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Cat 40–50 kg Cat 40–50 kg 2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Dog 8–10 kg Dog 8–10 kg 1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Dog 10–20 kg Dog 10–20 kg 1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Dog 20–30 kg Dog 20–30 kg 1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Dog 30–40 kg Dog 30–40 kg 2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
200 mg/50 mg, Scored tablet · Dog 40–50 kg Dog 40–50 kg 2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
Details: pack, label wording, sources, registration

Cladaxxa 200 mg/50 mg, Scored tablet

amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg
8.2/10
Very good
vetman assessment

Cladaxxa

200 mg/50 mg, amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 257-11 · Verified on 19 Oct 2026

A well-supported medium-dog strength with exact half-tablet bands and broad susceptible-infection utility. Stewardship, source control and reassessment remain essential despite the convenient presentation.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible 200/50 mg presentation is actively registered in Georgia and has a current detailed UK SPC with complete dose, resistance and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label, but response depends on susceptibility and source control; it does not cover Pseudomonas or MRSP and is not justified when a narrower drug works.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe renal impairment with anuria or oliguria are contraindications.

Clinical practicality8.1/10

Half-tablet 8-10 kg and whole-tablet 10-20 kg bands make this strength practical for medium dogs; twice-daily administration and longer selected courses remain an adherence burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg
8.0/10
Very good
vetman assessment

Cladaxxa

200 mg/50 mg, amoxicillin 200 mg + clavulanic acid 50 mg, divisible chewable tablet for cats and dogs
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 200/50 mg · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 257-11 · Verified on 19 Oct 2026

The medicine is clinically sound when susceptibility supports it, but this exact 200/50 mg presentation is a poor practical match for most cats. The score must not imply interchangeability with the smaller feline strength.

Regulatory and scientific credibility9.0/10

The exact presentation is actively registered in Georgia and has a current detailed UK SPC that includes cats, but the strength is only doseable from above 8 kg in the printed half-tablet bands.

Clinical efficacy8.0/10

The active combination is established for susceptible feline infections, but bacterial disease must first be confirmed and the drug does not cover Pseudomonas or MRSP; broad empirical use is poor stewardship.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe oliguric or anuric renal impairment are contraindications.

Clinical practicality6.8/10

The tablet is half-divisible but its first printed feline band is above 8-10 kg, so it is unsuitable for most cats; the 40/10 mg presentation is materially more doseable for typical feline weights.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin200 mg Clavulanic Acid50 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1180, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 200 მგ/50 მგ
№ 257-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 8–10 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 10–20 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 20–30 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 30–40 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Cat 40–50 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 8–10 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 10–20 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 20–30 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 30–40 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 40–50 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 200 mg/50 mg chewable tablets for cats and dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
400 mg/100 mg, Scored tablet · Dog 10–20 kg Dog 10–20 kg 1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
400 mg/100 mg, Scored tablet · Dog 20–40 kg Dog 20–40 kg 1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
400 mg/100 mg, Scored tablet · Dog 40–60 kg Dog 40–60 kg 1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
400 mg/100 mg, Scored tablet · Dog 60–80 kg Dog 60–80 kg 2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 · every 12 hours; usually 5-7 days		 every 12 hours; usually 5-7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
Details: pack, label wording, sources, registration

Cladaxxa 400 mg/100 mg, Scored tablet

amoxicillin 400 mg + clavulanic acid 100 mg, divisible chewable tablet for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.2/10
Very good
vetman assessment

Cladaxxa

400 mg/100 mg, amoxicillin 400 mg + clavulanic acid 100 mg, divisible chewable tablet for dogs
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, periodontal, urinary, respiratory and intestinal bacterial infections treated orally with Cladaxxa 400/100 mg · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 256-11 · Verified on 19 Oct 2026

A well-documented large-dog strength with practical half-tablet bands and broad susceptible-infection utility. Culture, source control and the narrowest effective antimicrobial remain decisive.

Regulatory and scientific credibility9.0/10

The exact chewable half-divisible 400/100 mg presentation is actively registered in Georgia and has a current detailed UK SPC with complete large-dog dose bands and safety information.

Clinical efficacy8.0/10

The combination is established for susceptible canine infections across the label, but efficacy depends on diagnosis, susceptibility and source control; Pseudomonas and MRSP are not covered and narrower therapy is preferred when adequate.

Safety and tolerability7.8/10

The expected profile is generally favourable, with gastrointestinal reactions and allergy as the main concerns; beta-lactam hypersensitivity and severe renal impairment with anuria or oliguria are contraindications.

Clinical practicality8.1/10

Half-tablet 10-20 kg through two-tablet 60-80 kg bands make this strength practical for larger dogs; twice-daily administration and longer selected courses still require adherence.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
  1. VMD SPC 20262026
  2. Georgia NFA register 20262026
  3. ISCAID 20252025
  4. ISCAID 20172017
  5. ISCAID urinary 20192019
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Amoxicillin400 mg Clavulanic Acid100 mg
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
KRKA, d.d., Novo mesto · Slovenia
Manufacturer (register)
KRKA, d.d., Novo mesto, Slovenia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1179, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: კლადაქსა 400 მგ/100 მგ
№ 256-11
Verified on: 19 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1/2 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 10–20 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 400 mg/100 mg chewable tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 tablet
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 20–40 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 400 mg/100 mg chewable tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
1 1/2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 40–60 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 400 mg/100 mg chewable tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
2 tablets
Standard label dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Determine body weight accurately. The tablet may be given directly or crumbled into a small amount of food. Longer courses: chronic skin infection 10-20 days; chronic cystitis 10-28 days. Refractory respiratory infection may require a doubled dose only on the responsible veterinarian's assessment. Do not use for MRSA/MRSP, beta-lactam hypersensitivity, or severe renal impairment with anuria/oliguria; not active against Pseudomonas spp.
 Dog 60–80 kg By mouth every 12 hours; usually 5-7 days
VMD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Cladaxxa 400 mg/100 mg chewable tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
Active substance doses, with sources
Active substance Amoxicillin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
10 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox palatable tablets 200 mg/50 mg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
20 mg/kg Dog Respiratory Tract Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox Palatable Drops 40 mg/ml + 10 mg/ml, Powder for Oral Suspension - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
7 mg/kg Dog, Cat Bacterial Infection Subcutaneous once daily for up to 5 days
Betamox 150 mg/ml, VMD SPC 2026
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Betamox 150 mg/ml Suspension for Injection - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
Active substance Clavulanic Acid
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
2.5 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox palatable tablets 200 mg/50 mg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Known Contraindications

  • Critical Amoxicillin
    Do not use in cases of hypersensitivity to the active substances, other substances of the beta-lactam group or to any of the excipients.
    Sources: VMD SPC · VMD
  • Critical Amoxicillin
    Do not use in animals with severe renal impairment with anuria or oliguria.
    Sources: VMD SPC · VMD
  • Warning Amoxicillin
    The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
    Sources: VMD SPC · VMD
  • Warning Amoxicillin
    The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
    Sources: VMD SPC · VMD

Known Drug Interactions

  • Major warning Amoxicillin + Doxycycline
    The bactericidal effect of amoxicillin may be inhibited by the concomitant use of bacteriostatic antimicrobials.
    Recommendation: If both are required, support the choice with culture and susceptibility results. Otherwise, choose one mechanism.
    Sources: VMD SPC · VMD
  • Major warning Amoxicillin + Oxytetracycline
    Do not give oxytetracycline at the same time as bactericidal antimicrobials such as penicillins or cephalosporins because their antibacterial effects may be antagonistic.
    Recommendation: Do not administer concurrently.
  • Minor warning Amoxicillin + Dihydrostreptomycin
    Penicillins may increase the effect of aminoglycosides.
    Recommendation: An enhanced effect is expected; monitor for aminoglycoside toxicity. Do not mix in the same syringe.
    Sources: VMD SPC · VMD
  • Minor warning Amoxicillin + Trimethoprim/Sulfonamide
    Concurrent use of bactericidal beta-lactam antibiotics and bacteriostatic antimicrobials such as sulfonamides is generally not recommended because their effects may be antagonistic.
    Recommendation: Avoid concomitant administration.

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 20 Oct 2026

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