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Nicilan

Amoxicillin + Clavulanic Acid · Laboratorios Calier S.A.

1 form: scored tablet. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
40 mg/10 mg, Scored tablet · Cat up to 2 kg Cat up to 2 kg 1/2 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Cat 2–5 kg Cat 2–5 kg 1 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Cat 5–9 kg Cat 5–9 kg 2 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Cat 9–13 kg Cat 9–13 kg 3 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Cat 13–18 kg Cat 13–18 kg 4 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Dog up to 2 kg Dog up to 2 kg 1/2 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Dog 2–5 kg Dog 2–5 kg 1 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Dog 5–9 kg Dog 5–9 kg 2 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Dog 9–13 kg Dog 9–13 kg 3 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
40 mg/10 mg, Scored tablet · Dog 13–18 kg Dog 13–18 kg 4 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
· every 12 hours, usually for 5-7 days
every 12 hours, usually for 5-7 days Georgia Yes, veterinary
Details: pack, label wording, sources, registration

Nicilan 40 mg/10 mg, Scored tablet

amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate
8.0/10
Very good
vetman assessment

Nicilan

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
Assessed clinical scopeDog · Full dog label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate · By mouth
Care settingOutpatient antimicrobial treatment after clinical diagnosis, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 267-11 · Verified on 19 Oct 2026

A well-documented broad oral antibiotic for genuinely susceptible canine infections. Its score assumes diagnosis-led, narrowest-effective prescribing and falls if it is used empirically for non-bacterial disease or where amoxicillin alone would suffice.

Regulatory and scientific credibility8.7/10

The exact divisible 40/10 mg product is actively registered in Georgia and has a current transparent EU regulator SPC; independent evidence is mainly at ingredient/class and syndrome-guideline level.

Clinical efficacy7.8/10

Amoxicillin/clavulanate is an established option for confirmed susceptible infections across the broad label, but efficacy depends on diagnosis and local susceptibility; it is not active against Pseudomonas or methicillin-resistant staphylococci and is often broader than necessary.

Safety and tolerability7.8/10

The therapeutic margin is generally favourable, but gastrointestinal reactions and uncommon hypersensitivity occur; beta-lactam allergy and severe renal impairment with anuria or oliguria are hard stops, and resistance selection matters.

Clinical practicality7.5/10

Twice-daily home dosing and a usual 5-7-day course are workable; the divisible tablet supports weight bands, but repeated administration, longer chronic courses and dose escalation only after reassessment add adherence and prescribing burden.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full cat label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate
8.0/10
Very good
vetman assessment

Nicilan

40 mg/10 mg, amoxicillin 40 mg + clavulanic acid 10 mg, divisible tablet for dogs and cats
Assessed clinical scopeCat · Full cat label: susceptible skin, soft-tissue, dental, urinary, respiratory and intestinal bacterial infections treated orally with amoxicillin/clavulanate · By mouth
Care settingOutpatient antimicrobial treatment after confirming bacterial disease, with culture and susceptibility testing whenever feasible
vetman score 8.0/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 267-11 · Verified on 19 Oct 2026

A well-supported oral option for confirmed susceptible feline bacterial disease, not a default treatment for undifferentiated respiratory, intestinal or lower urinary signs. Culture and the narrowest effective agent remain central.

Regulatory and scientific credibility8.7/10

The exact divisible 40/10 mg product is actively registered in Georgia and has a current transparent EU regulator SPC; independent evidence is mainly class-level and syndrome-specific guidance.

Clinical efficacy7.8/10

The combination is useful for confirmed susceptible feline infections, but most young cats with lower urinary signs do not have bacterial cystitis, susceptibility varies, and the drug does not cover Pseudomonas or methicillin-resistant staphylococci.

Safety and tolerability7.8/10

The therapeutic margin is generally favourable, but gastrointestinal reactions and uncommon hypersensitivity occur; beta-lactam allergy and severe renal impairment with anuria or oliguria are hard stops.

Clinical practicality7.5/10

The small divisible tablet fits common feline weight bands, but twice-daily home dosing, accurate half-tablet use and longer selected courses still require adherence and reassessment.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use after beta-lactam hypersensitivity; cross-reactions with penicillins and cephalosporins can be serious.
  • Do not use in severe renal impairment accompanied by anuria or oliguria.
  • Treat only a diagnosed susceptible bacterial infection; culture and susceptibility testing are preferred whenever feasible.
  • Do not use when narrow-spectrum penicillin or amoxicillin alone is expected to work; preserve clavulanate for beta-lactamase risk.
  • Do not expect activity against Pseudomonas spp. or methicillin-resistant staphylococci; reassess non-response rather than escalating blindly.
  • Monitor vomiting, diarrhoea, anorexia and allergic reactions; stop and treat significant hypersensitivity promptly.
  • Weigh accurately, use only the printed divisible-tablet bands, complete the selected course and reassess before doubling or prolonging treatment.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Formulation Type
Scored tablet
Administration route
By mouth
Manufacturer
Manufacturer (register)
LABORATORIOS CALIER, S.A, Spain
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1501, 19 Oct 2026.
Registration
Georgia Yes, veterinary
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1/2 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Cat up to 2 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
1 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Cat 2–5 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
2 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Cat 5–9 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
3 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Cat 9–13 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
4 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Cat 13–18 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
1/2 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Dog up to 2 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
1 tablet
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Dog 2–5 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
2 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Dog 5–9 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
3 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Dog 9–13 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
4 tablets
Give the label-table amount at the start of a meal. Standard dose: amoxicillin 10 mg/kg plus clavulanic acid 2.5 mg/kg every 12 hours. Use susceptibility testing and antimicrobial policy whenever possible. Do not use for infections susceptible to narrow-spectrum penicillin or amoxicillin alone, beta-lactam hypersensitivity, or serious renal dysfunction with anuria/oliguria.
Dog 13–18 kg By mouth every 12 hours, usually for 5-7 days
EU SPC 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Nicilan 40 mg/10 mg tablets for dogs and cats - Summary of Product Characteristics
EU Union Product Database, 2025
Active substance doses, with sources
Active substance Amoxicillin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
10 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox palatable tablets 200 mg/50 mg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
20 mg/kg Dog Respiratory Tract Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox Palatable Drops 40 mg/ml + 10 mg/ml, Powder for Oral Suspension - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
7 mg/kg Dog, Cat Bacterial Infection Subcutaneous once daily for up to 5 days
Betamox 150 mg/ml, VMD SPC 2026
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Betamox 150 mg/ml Suspension for Injection - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
Active substance Clavulanic Acid
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
2.5 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Synulox palatable tablets 200 mg/50 mg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Known Contraindications

  • Critical Amoxicillin
    Do not use in cases of hypersensitivity to the active substances, other substances of the beta-lactam group or to any of the excipients.
    Sources: VMD SPC · VMD
  • Critical Amoxicillin
    Do not use in animals with severe renal impairment with anuria or oliguria.
    Sources: VMD SPC · VMD
  • Warning Amoxicillin
    The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
    Sources: VMD SPC · VMD
  • Warning Amoxicillin
    The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
    Sources: VMD SPC · VMD

Known Drug Interactions

  • Major warning Amoxicillin + Doxycycline
    The bactericidal effect of amoxicillin may be inhibited by the concomitant use of bacteriostatic antimicrobials.
    Recommendation: If both are required, support the choice with culture and susceptibility results. Otherwise, choose one mechanism.
    Sources: VMD SPC · VMD
  • Major warning Amoxicillin + Oxytetracycline
    Do not give oxytetracycline at the same time as bactericidal antimicrobials such as penicillins or cephalosporins because their antibacterial effects may be antagonistic.
    Recommendation: Do not administer concurrently.
  • Minor warning Amoxicillin + Dihydrostreptomycin
    Penicillins may increase the effect of aminoglycosides.
    Recommendation: An enhanced effect is expected; monitor for aminoglycoside toxicity. Do not mix in the same syringe.
    Sources: VMD SPC · VMD
  • Minor warning Amoxicillin + Trimethoprim/Sulfonamide
    Concurrent use of bactericidal beta-lactam antibiotics and bacteriostatic antimicrobials such as sulfonamides is generally not recommended because their effects may be antagonistic.
    Recommendation: Avoid concomitant administration.

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.