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Biocan DHPPi+LR

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Canine distemper virus + Canine adenovirus + Canine parvovirus + Canine parainfluenza virus + Leptospira icterohaemorrhagiae + Leptospira canicola + Leptospira grippotyphosa + Rabies virus · Bioveta, a.s.

1 form: suspension. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Form Species Dose Frequency Georgia
Suspension · Dog Dog 1 ml (1 ml)
Aseptically reconstitute with the suspension, shake and immediately inject the entire 1 ml SC dose. The complete course requires Biocan DHPPi+L at 8-10 weeks followed 2-3 weeks later by DHPPi+LR, not before 12 weeks; repeat yearly. Vaccinate healthy dogs only. Antiparasitic treatment should precede vaccination by at least 10 days; avoid strenuous work for one week. Very rare hypersensitivity or a pea-sized local reaction lasting up to three weeks may occur. May be used in pregnancy, but avoid the final two weeks before whelping; lactation safety is not established. Other medicines require case-by-case assessment. Store 2-8 C, do not freeze, protect from light and use immediately after reconstitution.
 · one dose from 12 weeks after DHPPi+L 2-3 weeks earlier; then annually		 one dose from 12 weeks after DHPPi+L 2-3 weeks earlier; then annually Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბიოკან DHPPi+LR
№ 109-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Biocan DHPPi+LR, Suspension

lyophilisate and suspension, 1 ml dose for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.1/10
Very good
vetman assessment

Biocan DHPPi+LR

lyophilisate and suspension, 1 ml dose for dogs
Assessed clinical scopeDog · Full dog label from 12 weeks: annual all-in-one CDV, CAV, CPV, CPiV, three-serogroup leptospirosis and rabies immunisation after a Biocan DHPPi+L priming dose · Subcutaneous
Care settingPreventive veterinary vaccination of a healthy dog with examination, rabies certification where required and cold-chain control
vetman score 8.1/10 Very good
Evidence confidence: Medium Georgia: Yes, veterinary · № 109-11 · Verified on 21 Oct 2026

A very good, established all-in-one annual vaccine for settings that want rabies and leptospirosis in one injection. Newer four-serogroup, three-year-core products cover more leptospiral risk with fewer core boosters.

Regulatory and scientific credibility9.0/10

The exact presentation is registered in Georgia (109-11) and in Czechia since 2004 (97/016/04-C) with a current public SPC.

Clinical efficacy7.5/10

Live core antigens and inactivated rabies give useful protection with 14-day onset, but every component is labelled for one year only and the leptospiral fraction lacks the Australis serogroup that newer four-serogroup vaccines cover.

Safety and tolerability8.0/10

The label reports only very rare local or hypersensitivity reactions and permits use in pregnancy except the last two weeks before whelping.

Clinical practicality7.5/10

One annual 1 ml dose covers every component including rabies, but the puppy course needs a separate Biocan DHPPi+L dose 2-3 weeks earlier and the core antigens are boosted more often than modern guidelines require.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Give it from 12 weeks only after a Biocan DHPPi+L dose 2-3 weeks earlier; a single dose alone does not complete the label course for the non-rabies components.
  • The leptospiral fraction covers Icterohaemorrhagiae, Canicola and Grippotyphosa but not Australis; where Australis exposure matters, prefer a four-serogroup vaccine.
  • One rabies dose from 12 weeks is proven in the laboratory; before travel or in high-risk areas confirm the rabies titre or give a further dose.
  • Maternal antibody can interfere with the core response; finish the core series at 16 weeks or later when maternal antibody is likely.
  • Give antiparasitic treatment at least 10 days before vaccination and avoid strenuous exercise for a week after it. Observe for rare local or hypersensitivity reactions.
  • It may be used in pregnancy but avoid the last two weeks before whelping; safety in lactation is not established.
  • Store at 2-8 C, do not freeze and inject the whole reconstituted 1 ml immediately.
Assessment sources
  1. EU UPD SPC 20262026
  2. Georgia NFA register 20262026
  3. WSAVA vaccination 20242024
  4. ACVIM leptospirosis consensus 20232023
  5. AAHA canine vaccination 20222022
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Canine distemper virus3 log10 TCID50/dose Canine adenovirus3.5 log10 TCID50/dose Canine parvovirus4.5 log10 TCID50/dose Canine parainfluenza virus3 log10 TCID50/dose Leptospira icterohaemorrhagiae32 MAT titre/dose Leptospira canicola32 MAT titre/dose Leptospira grippotyphosa32 MAT titre/dose Rabies virus2 IU/dose
Formulation Type
Suspension
Administration route
Subcutaneous
Manufacturer
Bioveta, a.s. · Czechia
Manufacturer (register)
a.s. Bioveta a.s., Czechia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 824, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბიოკან DHPPi+LR
№ 109-11
Verified on: 21 Oct 2026
 EU Yes, veterinary
№ CZ 97/016/04-C
Verified on: 23 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
1 ml (1 ml)
Aseptically reconstitute with the suspension, shake and immediately inject the entire 1 ml SC dose. The complete course requires Biocan DHPPi+L at 8-10 weeks followed 2-3 weeks later by DHPPi+LR, not before 12 weeks; repeat yearly. Vaccinate healthy dogs only. Antiparasitic treatment should precede vaccination by at least 10 days; avoid strenuous work for one week. Very rare hypersensitivity or a pea-sized local reaction lasting up to three weeks may occur. May be used in pregnancy, but avoid the final two weeks before whelping; lactation safety is not established. Other medicines require case-by-case assessment. Store 2-8 C, do not freeze, protect from light and use immediately after reconstitution.
 Dog Any weight Subcutaneous one dose from 12 weeks after DHPPi+L 2-3 weeks earlier; then annually
EU UPD SPC 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Biocan DHPPi+LR - official SPC
EU Union Product Database, 2026

Canine distemper virus: No dose supported by a publicly verifiable source yet

Canine adenovirus: No dose supported by a publicly verifiable source yet

Canine parvovirus: No dose supported by a publicly verifiable source yet

Canine parainfluenza virus: No dose supported by a publicly verifiable source yet

Leptospira icterohaemorrhagiae: No dose supported by a publicly verifiable source yet

Leptospira canicola: No dose supported by a publicly verifiable source yet

Leptospira grippotyphosa: No dose supported by a publicly verifiable source yet

Rabies virus: No dose supported by a publicly verifiable source yet

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Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 23 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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