Details: pack, label wording, sources, registration
Bepanthen Plus, Cream
dexpanthenol 50 mg/g + chlorhexidine dihydrochloride 5 mg/g, cream 30 g, human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
Adjunctive topical care of a cleaned small superficial skin wound or abrasion with credible infection risk, after exclusion or separate management of deep injury, established infection and wounds requiring debridement, drainage or closure
5.0/10
Weak evidence support
Details →
vetman assessment
Bepanthen Plus
×
dexpanthenol 50 mg/g + chlorhexidine dihydrochloride 5 mg/g, cream 30 g, human medicine
Assessed clinical scope Dog · Adjunctive topical care of a cleaned small superficial skin wound or abrasion with credible infection risk, after exclusion or separate management of deep injury, established infection and wounds requiring debridement, drainage or closure · On the skin
Care setting Veterinarian-directed outpatient or inpatient use on a small accessible lesion with planned licking prevention, wound monitoring and escalation if healing or infection control is inadequate
vetman score
5.0/10
Weak evidence support
Evidence confidence: Low
Georgia: Yes, human · № რ-038463 · Verified on 22 Oct 2026
Off-label use
A weak, narrowly situational off-label option for a cleaned small superficial canine wound at infection risk. Chlorhexidine class evidence and exact human transparency support plausibility, but no exact-cream canine outcome or damaged-skin safety study justifies a stronger claim.
Regulatory and scientific credibility 6.0/10
The exact 30 g human cream has transparent composition, current Georgian and EU human authorisations and current official labels; canine chlorhexidine guidance and studies provide a scientific bridge. It has no veterinary authorisation or exact-product dog dossier, and salt, concentration, vehicle and clinical-scope transfer is substantial.
Clinical efficacy 4.0/10
Canine chlorhexidine data support topical antisepsis, including 0.5% healthy-skin and 0.05% wound-lavage evidence, while human dexpanthenol evidence supports a healing rationale. No canine trial tested exact Bepanthen Plus, dihydrochloride cream or the fixed combination; formulation-mismatched evidence caps efficacy at 4/10.
Safety and tolerability 4.5/10
Exact human risks and excipients are transparent, and 14-day 0.5% chlorhexidine gluconate exposure did not disrupt measured barrier function in six healthy dogs. Open/damaged skin, dihydrochloride cream, licking, lanolin/contact allergy and repeated-use tolerance remain untested; chlorhexidine is dangerous to the cornea.
Clinical practicality 6.0/10
The ready 30 g leave-on cream is simple to target to a small cleaned lesion and can be covered, with no preparation or mg/kg calculation. Reliable licking prevention, site exclusions, dressing surveillance and the absence of a validated veterinary amount/frequency add meaningful but manageable burden.
Full-course cost-effectiveness -
A current 30 g Georgian tube price was verified, but lesion-area-adjusted total course use, dressing needs, wastage and comparable veterinary alternatives were not; price is excluded from the denominator.
Important safety and use flags
This score covers only adjunctive care of a cleaned small superficial skin wound with credible infection risk. It does not cover deep, puncture/bite, devitalised, heavily contaminated, abscessed, large-area or established infected wounds, pyoderma generally, surgical closure or burns requiring specialist care. Bepanthen Plus is a human medicine and dog/cat use is off-label. No exact-product veterinary amount, frequency or course is established; do not copy the human up-to-four-times-daily label or another chlorhexidine product’s regimen. Examine and clean the wound first. Deep pockets, devitalised tissue, foreign material, bite/puncture injury, exudate, spreading inflammation, fever, pain or poor healing requires drainage, debridement, culture, closure or systemic treatment as clinically indicated. Keep away from eyes and periocular skin, mucosa and the ear canal when tympanic integrity is unknown. Chlorhexidine can cause severe corneal damage; ocular exposure requires immediate copious irrigation and urgent assessment if signs persist. Prevent licking and ingestion until the site is protected or the cream is no longer accessible. Use a collar or secure nonconstrictive dressing when needed, and inspect for maceration, pressure, swelling, discharge or impaired circulation. Stop immediately for increasing erythema, pruritus, pain, swelling, urticaria, facial swelling, breathing difficulty or another local/systemic hypersensitivity sign. Chlorhexidine can rarely cause anaphylaxis; lanolin, cetyl alcohol and stearyl alcohol can cause contact dermatitis. Do not apply over a large area or continue frequent repeated use without review. Exact damaged-skin absorption and repeated-use tolerance are unknown, and canine cell data show concentration-dependent chlorhexidine cytotoxicity even when short healthy-skin exposure appears acceptable. Do not combine on the same site with soaps/anionic compounds or another topical antiseptic without compatibility review. Organic debris can reduce topical antiseptic performance; cleaning and direct lesion contact matter. Do not use antibacterial cream where infection risk is not credible merely to promote healing. Avoid unnecessary antiseptic exposure and choose a non-antiseptic wound/barrier product when that better matches the diagnosed lesion. Safety in pregnant, lactating, breeding or juvenile dogs and cats is not established for repeated use on damaged skin. Make an explicit patient-specific benefit-risk decision and prevent neonate or littermate contact/ingestion. Assessment sources +
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Cat
Adjunctive topical care of a cleaned small superficial skin wound or abrasion with credible infection risk, after exclusion or separate management of deep injury, established infection and wounds requiring debridement, drainage or closure
4.2/10
Weak evidence support
Details →
vetman assessment
Bepanthen Plus
×
dexpanthenol 50 mg/g + chlorhexidine dihydrochloride 5 mg/g, cream 30 g, human medicine
Assessed clinical scope Cat · Adjunctive topical care of a cleaned small superficial skin wound or abrasion with credible infection risk, after exclusion or separate management of deep injury, established infection and wounds requiring debridement, drainage or closure · On the skin
Care setting Veterinarian-directed outpatient or inpatient use on a small accessible lesion with planned licking prevention, wound monitoring and escalation if healing or infection control is inadequate
vetman score
4.2/10
Weak evidence support
Evidence confidence: Low
Georgia: Yes, human · № რ-038463 · Verified on 22 Oct 2026
Off-label use
A weak off-label option with greater uncertainty in cats. A different rinse-off feline chlorhexidine product and mixed-species dexpanthenol data do not resolve leave-on efficacy, grooming ingestion or exact-product tolerance; use only when exposure can be controlled and better-supported care is not displaced.
Regulatory and scientific credibility 5.5/10
The exact 30 g human cream has transparent composition and current Georgian/EU human authorisation, and a different chlorhexidine rinse-off shampoo is authorised for cats. There is no exact-product feline dossier; salt, concentration, vehicle, wash-off versus leave-on use and disease scope differ materially.
Clinical efficacy 3.5/10
No exact-product feline outcome trial was found. A rinse-off chlorhexidine/miconazole shampoo label and a small mixed-species study of a different 10% dexpanthenol/decamethoxine ointment offer only indirect class plausibility and cannot establish this leave-on cream’s benefit.
Safety and tolerability 3.5/10
The rinse-off feline chlorhexidine label documents external-use, eye, licking and rare local-reaction precautions, but exact leave-on cream tolerance, damaged-skin exposure and grooming ingestion are unknown. Corneal injury and serious hypersensitivity are hard stops, and lanolin/cetyl/stearyl alcohol can cause contact dermatitis.
Clinical practicality 4.5/10
Application to a small lesion is simple, but a grooming cat often requires a collar or secure nonconstrictive dressing, repeated handling and close skin checks. Eye/ear/mucosa exclusions and no validated feline amount/frequency materially reduce practicality.
Full-course cost-effectiveness -
A current 30 g Georgian tube price was verified, but lesion-area-adjusted total course use, dressing needs, wastage and comparable veterinary alternatives were not; price is excluded from the denominator.
Important safety and use flags
This score covers only adjunctive care of a cleaned small superficial skin wound with credible infection risk. It does not cover deep, puncture/bite, devitalised, heavily contaminated, abscessed, large-area or established infected wounds, pyoderma generally, surgical closure or burns requiring specialist care. Bepanthen Plus is a human medicine and dog/cat use is off-label. No exact-product veterinary amount, frequency or course is established; do not copy the human up-to-four-times-daily label or another chlorhexidine product’s regimen. Examine and clean the wound first. Deep pockets, devitalised tissue, foreign material, bite/puncture injury, exudate, spreading inflammation, fever, pain or poor healing requires drainage, debridement, culture, closure or systemic treatment as clinically indicated. Keep away from eyes and periocular skin, mucosa and the ear canal when tympanic integrity is unknown. Chlorhexidine can cause severe corneal damage; ocular exposure requires immediate copious irrigation and urgent assessment if signs persist. Prevent licking and ingestion until the site is protected or the cream is no longer accessible. Use a collar or secure nonconstrictive dressing when needed, and inspect for maceration, pressure, swelling, discharge or impaired circulation. Stop immediately for increasing erythema, pruritus, pain, swelling, urticaria, facial swelling, breathing difficulty or another local/systemic hypersensitivity sign. Chlorhexidine can rarely cause anaphylaxis; lanolin, cetyl alcohol and stearyl alcohol can cause contact dermatitis. Do not apply over a large area or continue frequent repeated use without review. Exact damaged-skin absorption and repeated-use tolerance are unknown, and canine cell data show concentration-dependent chlorhexidine cytotoxicity even when short healthy-skin exposure appears acceptable. Do not combine on the same site with soaps/anionic compounds or another topical antiseptic without compatibility review. Organic debris can reduce topical antiseptic performance; cleaning and direct lesion contact matter. Do not use antibacterial cream where infection risk is not credible merely to promote healing. Avoid unnecessary antiseptic exposure and choose a non-antiseptic wound/barrier product when that better matches the diagnosed lesion. Safety in pregnant, lactating, breeding or juvenile dogs and cats is not established for repeated use on damaged skin. Make an explicit patient-specific benefit-risk decision and prevent neonate or littermate contact/ingestion. Assessment sources +
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Administration route
On the skin
Registration
Georgia
Yes, human
In force until 28 Jun 2028
Human (Ministry of Health, RAMA)
№ რ-038463
Verified on: 22 Oct 2026
EU
Yes, human
UK
No
US
No
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified
No exact-product dog/cat amount, frequency or course is established. Potential off-label use is limited to veterinarian-assessed, cleaned, small superficial skin wounds with infection risk. Prevent licking and use a secure nonconstrictive dressing or collar when needed. Do not copy the human up-to-four-times-daily direction or another chlorhexidine product’s regimen.
