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Benevron BF

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Thiamine + Pyridoxine + Riboflavin + Folic acid + Cyanocobalamin · World Medicine İlaç San. ve Tic. A.Ş.

1 form: coated tablet. In force in Georgia: 1 of 1 (human register).

Forms and doses1 of 1 in force in Georgia

Form Dose Frequency Georgia
20 gastro-resistant tablets, Coated tablet No label dose in the reference yet - Georgia Yes, human
In force until 08 Sep 2031
Human (Ministry of Health, RAMA)
№ რ-046262, რ-044386
Verified on: 15 Oct 2026
Details: pack, label wording, sources, registration

Benevron BF 20 gastro-resistant tablets, Coated tablet

human medicine
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Proposed oral use of the exact Benevron BF human gastro-resistant product for a diagnosed vitamin deficiency or adjunctive neurologic role
Not rateable
No numerical score assigned
vetman assessment

Benevron BF

20 gastro-resistant tablets, human medicine
Assessed clinical scopeDog · Proposed oral use of the exact Benevron BF human gastro-resistant product for a diagnosed vitamin deficiency or adjunctive neurologic role · By mouth
Care settingVeterinarian-directed use only after diagnosis and selection of a source-backed, deliverable regimen
vetman score Not rateable No numerical score assigned
Evidence confidence: Low Georgia: Yes, human · № რ-046262, რ-044386 · Verified on 15 Oct 2026 Off-label use
Not rateable

A numerical canine score cannot be assigned responsibly. AEM DV 25-00460 verifies the Azerbaijani gastro-resistant medicine, while the exact World Medicine Kazakhstan document describes the same name, composition and 20-tablet presentation as a food supplement. Neither source establishes a dog/cat regimen, veterinary PK, target-animal safety or outcomes; neither establishes a validated veterinary fraction.

Exact identity is documented, but the regulatory category differs by jurisdiction and no veterinary dose or validated tablet fraction is established.

Important safety and use flags

  • Use only for a defined deficiency or other explicit clinical rationale. A nonspecific neurologic sign, anorexia, fatigue or routine supplementation is not a diagnosis.
  • No dog or cat dose is established for this exact product. Do not restore a quarter-tablet practice or derive a fraction by arithmetic.
  • The exact presentation is gastro-resistant, but the audited primary documents do not establish scoring, equal-dose subdivision, whole-only administration or crushing instructions. Do not invent any of them.
  • AEM records a human medicine in Azerbaijan; the exact World Medicine Kazakhstan document calls the same name/composition/presentation a food supplement. Keep the jurisdiction-specific categories distinct.
  • Do not infer that all B vitamins are required because one deficiency is plausible. Ingredient or comparator evidence cannot validate this fixed high-dose ratio or transfer another product’s dose.
  • Each tablet contains 200 mg pyridoxine with four other vitamins. No product-specific dog/cat exposure threshold, safe duration or therapeutic margin is established.
  • High experimental pyridoxine exposure caused sensory-neuron injury in dogs. Those studies do not define a safe lower Benevron regimen, but they rule out assuming that water solubility makes chronic high-dose exposure harmless.
  • Review hypersensitivity to active ingredients and excipients. The exact product document lists sulfite and paraben excipients; target-animal tolerability is not established.
  • Review the full medication plan, especially levodopa without a peripheral decarboxylase inhibitor and other vitamin-containing products. Avoid unexamined cumulative exposure.
  • Set a diagnosis-specific response point and stop date. If response is absent, reassess diet, malabsorption, antagonists, primary disease and the actual deficient nutrient rather than continuing empirical B-complex treatment.
Assessment sources
  1. Benevron BF Azerbaijan register2025
  2. Benevron BF manufacturer document2026
  3. Small-animal nutrition2026
  4. Feline thiamine case2010
  5. Veterinary B12 comparator2025
  6. Canine oral pyridoxine toxicity1981
  7. Canine parenteral pyridoxine toxicity2008
Assessed: 23 Oct 2026No axis or overall score is shown when the available evidence does not support a responsible numerical assessment.
Cat Proposed oral use of the exact Benevron BF human gastro-resistant product for a diagnosed vitamin deficiency or adjunctive neurologic role
Not rateable
No numerical score assigned
vetman assessment

Benevron BF

20 gastro-resistant tablets, human medicine
Assessed clinical scopeCat · Proposed oral use of the exact Benevron BF human gastro-resistant product for a diagnosed vitamin deficiency or adjunctive neurologic role · By mouth
Care settingVeterinarian-directed use only after diagnosis and selection of a source-backed, deliverable regimen
vetman score Not rateable No numerical score assigned
Evidence confidence: Low Georgia: Yes, human · № რ-046262, რ-044386 · Verified on 15 Oct 2026 Off-label use
Not rateable

A numerical feline score cannot be assigned responsibly. AEM DV 25-00460 verifies the Azerbaijani gastro-resistant medicine, while the exact World Medicine Kazakhstan document describes the same name, composition and 20-tablet presentation as a food supplement. Neither source establishes a dog/cat regimen, veterinary PK, target-animal safety or outcomes; neither establishes a validated veterinary fraction.

Exact identity is documented, but the regulatory category differs by jurisdiction and no veterinary dose or validated tablet fraction is established.

Important safety and use flags

  • Use only for a defined deficiency or other explicit clinical rationale. A nonspecific neurologic sign, anorexia, fatigue or routine supplementation is not a diagnosis.
  • No dog or cat dose is established for this exact product. Do not restore a quarter-tablet practice or derive a fraction by arithmetic.
  • The exact presentation is gastro-resistant, but the audited primary documents do not establish scoring, equal-dose subdivision, whole-only administration or crushing instructions. Do not invent any of them.
  • AEM records a human medicine in Azerbaijan; the exact World Medicine Kazakhstan document calls the same name/composition/presentation a food supplement. Keep the jurisdiction-specific categories distinct.
  • Do not infer that all B vitamins are required because one deficiency is plausible. Ingredient or comparator evidence cannot validate this fixed high-dose ratio or transfer another product’s dose.
  • Each tablet contains 200 mg pyridoxine with four other vitamins. No product-specific dog/cat exposure threshold, safe duration or therapeutic margin is established.
  • High experimental pyridoxine exposure caused sensory-neuron injury in dogs. Those studies do not define a safe lower Benevron regimen, but they rule out assuming that water solubility makes chronic high-dose exposure harmless.
  • Review hypersensitivity to active ingredients and excipients. The exact product document lists sulfite and paraben excipients; target-animal tolerability is not established.
  • Review the full medication plan, especially levodopa without a peripheral decarboxylase inhibitor and other vitamin-containing products. Avoid unexamined cumulative exposure.
  • Set a diagnosis-specific response point and stop date. If response is absent, reassess diet, malabsorption, antagonists, primary disease and the actual deficient nutrient rather than continuing empirical B-complex treatment.
Assessment sources
  1. Benevron BF Azerbaijan register2025
  2. Benevron BF manufacturer document2026
  3. Small-animal nutrition2026
  4. Feline thiamine case2010
  5. Veterinary B12 comparator2025
  6. Canine oral pyridoxine toxicity1981
  7. Canine parenteral pyridoxine toxicity2008
Assessed: 23 Oct 2026No axis or overall score is shown when the available evidence does not support a responsible numerical assessment.
Composition / strength
Thiamine250 mg Pyridoxine200 mg Riboflavin15 mg Folic acid0.5 mg Cyanocobalamin0.25 mg
Formulation Type
Coated tablet
Administration route
By mouth
Registration
Georgia Yes, human
In force until 08 Sep 2031
Human (Ministry of Health, RAMA)
№ რ-046262, რ-044386
Verified on: 15 Oct 2026
 EU No
Verified on: 16 Oct 2026
 UK No
Verified on: 16 Oct 2026
 US No
Verified on: 16 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified No dog or cat dose was identified for this exact high-dose five-vitamin gastro-resistant product. The exact public documents contain human directions only and do not establish tablet subdivision, crushing, veterinary exposure or a treatment course.

The dose of a combination product is determined by its own product information. The doses below apply to the individual active substances and should not be used as the dose of this product.

Active substance doses, with sources
Active substance Folic acid
Dose Species Indication Route Frequency Source
5 mg per animal
off-label
 Dog Maintenance By mouth once daily for 1 month
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Drugs Acting on the Blood or Blood-Forming Organs in Animals
MSD/Merck Veterinary Manual, 2025
2.5 mg per animal
off-label
 Cat Maintenance By mouth once daily for 1 month
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Drugs Acting on the Blood or Blood-Forming Organs in Animals
MSD/Merck Veterinary Manual, 2025
Active substance Cyanocobalamin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
25 mcg/kg
off-label
 Dog Maintenance By mouth once daily
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Exocrine Pancreatic Insufficiency in Dogs and Cats
MSD/Merck Veterinary Manual, 2025
25 mcg/kg
off-label
 Dog Maintenance Subcutaneous once weekly
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Exocrine Pancreatic Insufficiency in Dogs and Cats
MSD/Merck Veterinary Manual, 2025
0.25 mg per animal
off-label
 Cat Maintenance By mouth once daily
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Exocrine Pancreatic Insufficiency in Dogs and Cats
MSD/Merck Veterinary Manual, 2025
0.25 mg per animal
off-label
 Cat Maintenance Subcutaneous once weekly
MSD Vet Manual 2025
Reference book
A veterinary reference written and reviewed by specialists, summarising accepted practice. The product label gives the authorised dose.
Exocrine Pancreatic Insufficiency in Dogs and Cats
MSD/Merck Veterinary Manual, 2025

Thiamine: No dose supported by a publicly verifiable source yet

Pyridoxine: No dose supported by a publicly verifiable source yet

Riboflavin: No dose supported by a publicly verifiable source yet

Known Contraindications

  • Warning Cyanocobalamin
    Tumours: according to the product label, vitamin B12 may stimulate the growth of malignant tumours, so it should not be given to patients with a tumour.
    Sources: Product label
  • Critical Pyridoxine
    A whole tablet is a large dose for a small animal: one tablet contains 200 mg pyridoxine, which is 50 mg/kg for a 4 kg cat. The label's overdose section describes pyridoxine neuropathy in people after months or years of chronic intake of 200 to 6000 mg a day (roughly 3 to 100 mg/kg a day). In practice an adult cat is given a quarter of a tablet (see the product note): 12.5 mg/kg pyridoxine for a 4 kg cat, in the lower third of that range. A short course and a long one are different questions. No source gives a veterinary dose for this combination.
    Sources: Product label
  • Critical Pyridoxine
    Kidney failure: the human product label makes kidney or liver failure an absolute contraindication. This is a pharmacological restriction and does not depend on the species.
    Sources: Product label
  • Critical Pyridoxine
    Hepatic impairment is listed as an absolute contraindication on the human product label, alongside renal impairment.
    Sources: Product label
  • Warning Pyridoxine
    Pregnancy and lactation are contraindications on the human product label because of the high vitamin doses rather than the vitamins themselves. This restriction cannot be transferred directly to animals, but it applies to the doses contained in this tablet.
    Sources: Product label
  • Warning Thiamine
    Sodium metabisulfite (E223) can rarely cause severe hypersensitivity reactions and bronchospasm. The tablet also contains the azo dyes Ponceau 4R (E124) and Sunset Yellow (E110). Riboflavin can turn urine yellow; this is expected and is not an adverse effect.
    Sources: Product label

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

Show all related products (19 more) Hide additional products

Same therapeutic group 19

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 16 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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