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Pronefra

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Calcium Carbonate + Hydrolysed fish protein (marine oligopeptides) + Chitosan + Magnesium Carbonate · Virbac

1 form: suspension. Not applicable (not a medicine).

Forms and dosesNot applicable (not a medicine)

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Dose Frequency Georgia
Suspension · Cat Cat 0.25 ml/kg
Cats: 1 ml per 4 kg (0.25 ml/kg) twice daily. Shake well before every use. Give with or around meals, mixed into food or directly into the mouth with the supplied syringe. Keep drinking water available. Do not exceed the recommended amount. The manufacturer notes that it may not suit some older or medically treated animals with digestive sensitivity. This is a complementary feed, not a medicine.
 · twice daily with or around meals		 twice daily with or around meals Georgia Not a medicine
Not applicable (not a medicine)
In the register: პრონეფრა
Verified on: 20 Oct 2026
Suspension · Dog Dog 0.2 ml/kg
Dogs: 1 ml per 5 kg (0.2 ml/kg) twice daily. Shake well before every use. Give with or around meals, mixed into food or directly into the mouth with the supplied syringe. Keep drinking water available. Do not exceed the recommended amount. The manufacturer notes that it may not suit some older or medically treated animals with digestive sensitivity. This is a complementary feed, not a medicine.
 · twice daily with or around meals		 twice daily with or around meals Georgia Not a medicine
Not applicable (not a medicine)
In the register: პრონეფრა
Verified on: 20 Oct 2026
Details: pack, label wording, sources, registration

Pronefra, Suspension

oral suspension, 60 ml and 180 ml, complementary feed for adult dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Adjunctive enteric phosphate binding in adult dogs with CKD when dietary phosphate restriction alone is insufficient
7.1/10
Good
vetman assessment

Pronefra

oral suspension, 60 ml and 180 ml, complementary feed for adult dogs and cats
Assessed clinical scopeDog · Adjunctive enteric phosphate binding in adult dogs with CKD when dietary phosphate restriction alone is insufficient · By mouth
Care settingVeterinary-directed outpatient CKD management with serial phosphate and calcium monitoring
vetman score 7.1/10 Good
Evidence confidence: Medium Georgia: Not a medicine · Verified on 20 Oct 2026

A practical adjunctive phosphate binder with a transparent formula; use only when the patient needs binding and titrate against laboratory targets.

Regulatory and scientific credibility6.5/10

The current exact formula and species-specific dose are transparent, and its complementary-feed status is correctly documented; it is not a medicinal product and lacks a regulator-reviewed efficacy dossier.

Clinical efficacy6.5/10

Calcium carbonate is a guideline-recognised enteric phosphate binder, but benefit must be titrated to serum phosphate and independent outcome evidence for this exact multi-ingredient product is limited.

Safety and tolerability7.5/10

Sponsor-reported tolerance is generally good, but calcium-containing binders require calcium monitoring and the product should not be used as an unmonitored routine supplement.

Clinical practicality8.5/10

The oral suspension has clear weight-based dosing, is given twice daily with meals and has favourable acceptance data; shaking and accurate syringe measurement remain necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Use only when dietary phosphate restriction is insufficient; titrate to serum phosphate and monitor calcium.
  • Independent clinical outcome evidence for the exact four-component product is limited.
Assessment sources
  1. Virbac 20262026
  2. iCatCare CKD 20262026
  3. ECVIM Pronefra 20202020
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Adjunctive enteric phosphate binding in adult cats with CKD when dietary phosphate restriction alone is insufficient
7.1/10
Good
vetman assessment

Pronefra

oral suspension, 60 ml and 180 ml, complementary feed for adult dogs and cats
Assessed clinical scopeCat · Adjunctive enteric phosphate binding in adult cats with CKD when dietary phosphate restriction alone is insufficient · By mouth
Care settingVeterinary-directed outpatient CKD management with serial phosphate and calcium monitoring
vetman score 7.1/10 Good
Evidence confidence: Medium Georgia: Not a medicine · Verified on 20 Oct 2026

A practical adjunctive phosphate binder with a transparent formula; use only when the patient needs binding and titrate against laboratory targets.

Regulatory and scientific credibility6.5/10

The current exact formula and species-specific dose are transparent, and its complementary-feed status is correctly documented; it is not a medicinal product and lacks a regulator-reviewed efficacy dossier.

Clinical efficacy6.5/10

Calcium carbonate is a guideline-recognised enteric phosphate binder, but benefit must be titrated to serum phosphate and independent outcome evidence for this exact multi-ingredient product is limited.

Safety and tolerability7.5/10

Sponsor-reported tolerance is generally good, but calcium-containing binders require calcium monitoring and the product should not be used as an unmonitored routine supplement.

Clinical practicality8.5/10

The oral suspension has clear weight-based dosing, is given twice daily with meals and has favourable acceptance data; shaking and accurate syringe measurement remain necessary.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Use only when dietary phosphate restriction is insufficient; titrate to serum phosphate and monitor calcium.
  • Independent clinical outcome evidence for the exact four-component product is limited.
Assessment sources
  1. Virbac 20262026
  2. iCatCare CKD 20262026
  3. ECVIM Pronefra 20202020
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Calcium Carbonate3.6 % Hydrolysed fish protein (marine oligopeptides)1.9 % Chitosan1 % Magnesium Carbonate1 %
Formulation Type
Suspension
Administration route
By mouth
Manufacturer
Virbac · France
Registration
Georgia Not a medicine
Not applicable (not a medicine)
In the register: პრონეფრა
Verified on: 20 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
0.25 ml/kg
Cats: 1 ml per 4 kg (0.25 ml/kg) twice daily. Shake well before every use. Give with or around meals, mixed into food or directly into the mouth with the supplied syringe. Keep drinking water available. Do not exceed the recommended amount. The manufacturer notes that it may not suit some older or medically treated animals with digestive sensitivity. This is a complementary feed, not a medicine.
 Cat Any weight By mouth twice daily with or around meals
Virbac 2026
Manufacturer material
Information published by the maker or a seller, such as a datasheet or product page. A medicines regulator has not necessarily reviewed it.
Pronefra oral suspension for dogs and cats - official product information
Virbac France, 2026
0.2 ml/kg
Dogs: 1 ml per 5 kg (0.2 ml/kg) twice daily. Shake well before every use. Give with or around meals, mixed into food or directly into the mouth with the supplied syringe. Keep drinking water available. Do not exceed the recommended amount. The manufacturer notes that it may not suit some older or medically treated animals with digestive sensitivity. This is a complementary feed, not a medicine.
 Dog Any weight By mouth twice daily with or around meals
Virbac 2026
Manufacturer material
Information published by the maker or a seller, such as a datasheet or product page. A medicines regulator has not necessarily reviewed it.
Pronefra oral suspension for dogs and cats - official product information
Virbac France, 2026

Calcium Carbonate: No dose supported by a publicly verifiable source yet

Hydrolysed fish protein (marine oligopeptides): No dose supported by a publicly verifiable source yet

Chitosan: No dose supported by a publicly verifiable source yet

Magnesium Carbonate: No dose supported by a publicly verifiable source yet

Known Drug Interactions

  • Minor warning Oxytetracycline + Calcium Carbonate
    Divalent and trivalent cations, including magnesium, iron, aluminium, and calcium, can chelate oxytetracycline and reduce its absorption. Do not give it at the same time as milk or antacids.
    Recommendation: Separate this medicine from oral oxytetracycline in time.
  • Minor warning Levothyroxine + Calcium Carbonate
    Antacids containing aluminium, magnesium, or calcium, as well as ferrous sulfate and sucralfate, can reduce levothyroxine absorption.
    Recommendation: Separate levothyroxine from antacids, iron, or sucralfate by at least 2 hours.
  • Minor warning Oxytetracycline + Magnesium Carbonate
    Divalent and trivalent cations, including magnesium, iron, aluminium, and calcium, can chelate oxytetracycline and reduce its absorption. Do not give it at the same time as milk or antacids.
    Recommendation: Separate this medicine from oral oxytetracycline in time.
  • Minor warning Levothyroxine + Magnesium Carbonate
    Antacids containing aluminium, magnesium, or calcium, as well as ferrous sulfate and sucralfate, can reduce levothyroxine absorption.
    Recommendation: Separate levothyroxine from antacids, iron, or sucralfate by at least 2 hours.

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

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Same therapeutic group 21

Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

For veterinary professionals only. It does not replace clinical judgement or the product label; check the dose in the official label (SPC). vetman is not liable for harm caused by using this information.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 20 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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