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Stomorgyl 2

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Spiramycin + Metronidazole · Merial

1 form: tablet. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Dose Frequency Georgia
Tablet · Cat Cat 1 tablet per 2 kg
Give one tablet per 2 kg body weight once daily for 5-10 days. Each tablet contains spiramycin 150000 IU and metronidazole 25 mg. Do not combine with another macrolide antibiotic. Massive overdose may cause tremor, spasm or ataxia; discontinue treatment. Pregnancy advice differs between national product documents, so verify the current Georgian leaflet and use only on the responsible veterinarian's assessment. The bound source does not establish tablet subdivision; a calculated fraction therefore may not be deliverable.
 · once daily for 5-10 days		 once daily for 5-10 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტომორგილი 2
№ 215-11
Verified on: 19 Oct 2026
Tablet · Dog Dog 1 tablet per 2 kg
Give one tablet per 2 kg body weight once daily for 5-10 days. Each tablet contains spiramycin 150000 IU and metronidazole 25 mg. Do not combine with another macrolide antibiotic. Massive overdose may cause tremor, spasm or ataxia; discontinue treatment. Pregnancy advice differs between national product documents, so verify the current Georgian leaflet and use only on the responsible veterinarian's assessment. The bound source does not establish tablet subdivision; a calculated fraction therefore may not be deliverable.
 · once daily for 5-10 days		 once daily for 5-10 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტომორგილი 2
№ 215-11
Verified on: 19 Oct 2026
Details: pack, label wording, sources, registration

Stomorgyl 2, Tablet

Spiramycin 150000 IU + metronidazole 25 mg tablet for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Adjunct oral spiramycin/metronidazole for diagnosed susceptible periodontal or related oral infection, with indicated professional dental or surgical source control; not routine prophylaxis or first-line empirical treatment
6.7/10
Situational / acceptable
vetman assessment

Stomorgyl 2

Spiramycin 150000 IU + metronidazole 25 mg tablet for dogs and cats
Assessed clinical scopeDog · Adjunct oral spiramycin/metronidazole for diagnosed susceptible periodontal or related oral infection, with indicated professional dental or surgical source control; not routine prophylaxis or first-line empirical treatment · By mouth
Care settingVeterinary-directed course after oral examination and treatment planning, with professional cleaning, endodontic treatment, extraction or surgery when indicated and reassessment if response is inadequate
vetman score 6.7/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, veterinary · № 215-11 · Verified on 19 Oct 2026

A well-identified veterinary strength for selected susceptible oral infection in small dogs, with convenient once-daily whole-unit dosing. Its role is adjunctive: dental source control comes first, direct clinical outcome evidence is limited and antimicrobial/neurotoxicity precautions remain material.

Regulatory and scientific credibility8.0/10

The exact veterinary presentation has a sourced current Georgian registration and independently verified EU/EEA product information defining its strength, species, oral route and regimen. The dossier is transparent, although independent exact-product clinical outcome evidence remains limited.

Clinical efficacy5.5/10

The authorised spectrum fits mixed susceptible periodontal flora, and a six-dog study found a treatment-time reduction in selected dental-biofilm taxa. It did not test clinical cure, recurrence or superiority, while current dental and stewardship guidance makes source control primary and systemic antibiotics selective rather than routine.

Safety and tolerability6.0/10

The labelled 5-10-day course has a useful safety margin and gastrointestinal reactions are very rare, but metronidazole adds dose- and duration-related neurologic and genotoxic uncertainty, reproductive safety is not established, and concurrent macrolides are prohibited. Hepatic disease requires particular caution and is contraindicated by the bound Stomorgyl 20 label.

Clinical practicality7.5/10

Once-daily dosing for 5-10 days and the 1-tablet/2-kg strength are workable for many cats and small dogs. The tablet must remain whole, so patients whose calculated dose is not a whole 2-kg unit need another authorised strength or presentation.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use this combination as routine dental prophylaxis or first-line empirical periodontal treatment. Examine and stage the mouth; professional cleaning, endodontic treatment, extraction or surgery is primary source control and must not be replaced by tablets.
  • Reserve treatment for a diagnosed susceptible aerobic/anaerobic oral infection when systemic antimicrobial benefit is expected. Obtain culture and susceptibility when feasible, follow local antimicrobial policy, use the shortest justified label course and reassess treatment failure rather than repeating empirically.
  • Do not administer concurrently with another macrolide antibiotic. Review the full medication list for additive antimicrobial exposure and avoid combining products that duplicate metronidazole.
  • Stop and assess promptly for ataxia, tremor, nystagmus, spasm, seizure, weakness or altered mentation. Metronidazole neurotoxicity is related to exposure and duration and cannot be dismissed because the planned course is short.
  • Safety in pregnancy and lactation is not established consistently across national Stomorgyl information. Verify the exact current Georgian leaflet and use only after an individual veterinary benefit-risk assessment; avoid unnecessary exposure.
  • Hepatic dysfunction can increase metronidazole exposure. Assess liver disease before use, limit duration and monitor closely; the bound Stomorgyl 20 label contraindicates use in hepatic disease.
  • Vomiting, diarrhoea or anorexia may occur. Record response and adverse effects, and remember that broad combination therapy alters oral and intestinal microbial ecology and selects resistance even when short-term tolerance appears good.
  • Give whole tablets only: one tablet corresponds to 2 kg. Do not divide or crush; if the calculated dose is not a whole 2-kg unit, choose another authorised strength or accurately deliverable presentation.
Assessment sources
  1. Stomorgyl market audit2026
  2. EU SPC2026
  3. Same-combination stewardship label2025
  4. WSAVA dental guideline2026
  5. AAHA dental guideline2019
  6. AAFP AAHA stewardship2022
  7. Canine dental biofilm study2022
  8. Canine neurotoxicity series2018
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Adjunct oral spiramycin/metronidazole for diagnosed susceptible periodontal or related oral infection, with indicated professional dental or surgical source control; not routine prophylaxis or first-line empirical treatment
6.5/10
Situational / acceptable
vetman assessment

Stomorgyl 2

Spiramycin 150000 IU + metronidazole 25 mg tablet for dogs and cats
Assessed clinical scopeCat · Adjunct oral spiramycin/metronidazole for diagnosed susceptible periodontal or related oral infection, with indicated professional dental or surgical source control; not routine prophylaxis or first-line empirical treatment · By mouth
Care settingVeterinary-directed course after oral examination and treatment planning, with professional cleaning, endodontic treatment, extraction or surgery when indicated and reassessment if response is inadequate
vetman score 6.5/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, veterinary · № 215-11 · Verified on 19 Oct 2026

A well-identified feline-authorised strength whose 2-kg whole-unit step is workable for many cats. Use only for selected susceptible oral infection alongside dental source control; direct feline outcome evidence is absent and antimicrobial/neurotoxicity precautions remain material.

Regulatory and scientific credibility8.0/10

The exact veterinary presentation has a sourced current Georgian registration and independently verified EU/EEA product information defining its strength, species, oral route and regimen. The dossier is transparent, although independent exact-product clinical outcome evidence remains limited.

Clinical efficacy5.0/10

The product is authorised for cats and its spectrum plausibly covers susceptible mixed oral flora, but no applicable independent feline clinical outcome trial was found. Dental and stewardship guidance makes source control primary and systemic antibiotics selective, so efficacy confidence is lower than in dogs.

Safety and tolerability6.0/10

The labelled 5-10-day course has a useful safety margin and gastrointestinal reactions are very rare, but metronidazole adds dose- and duration-related neurologic and genotoxic uncertainty, reproductive safety is not established, and concurrent macrolides are prohibited. Hepatic disease requires particular caution and is contraindicated by the bound Stomorgyl 20 label.

Clinical practicality7.5/10

Once-daily dosing for 5-10 days and the 1-tablet/2-kg strength are workable for many cats and small dogs. The tablet must remain whole, so patients whose calculated dose is not a whole 2-kg unit need another authorised strength or presentation.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use this combination as routine dental prophylaxis or first-line empirical periodontal treatment. Examine and stage the mouth; professional cleaning, endodontic treatment, extraction or surgery is primary source control and must not be replaced by tablets.
  • Reserve treatment for a diagnosed susceptible aerobic/anaerobic oral infection when systemic antimicrobial benefit is expected. Obtain culture and susceptibility when feasible, follow local antimicrobial policy, use the shortest justified label course and reassess treatment failure rather than repeating empirically.
  • Do not administer concurrently with another macrolide antibiotic. Review the full medication list for additive antimicrobial exposure and avoid combining products that duplicate metronidazole.
  • Stop and assess promptly for ataxia, tremor, nystagmus, spasm, seizure, weakness or altered mentation. Metronidazole neurotoxicity is related to exposure and duration and cannot be dismissed because the planned course is short.
  • Safety in pregnancy and lactation is not established consistently across national Stomorgyl information. Verify the exact current Georgian leaflet and use only after an individual veterinary benefit-risk assessment; avoid unnecessary exposure.
  • Hepatic dysfunction can increase metronidazole exposure. Assess liver disease before use, limit duration and monitor closely; the bound Stomorgyl 20 label contraindicates use in hepatic disease.
  • Vomiting, diarrhoea or anorexia may occur. Record response and adverse effects, and remember that broad combination therapy alters oral and intestinal microbial ecology and selects resistance even when short-term tolerance appears good.
  • Give whole tablets only: one tablet corresponds to 2 kg. Do not divide or crush; if the calculated dose is not a whole 2-kg unit, choose another authorised strength or accurately deliverable presentation.
Assessment sources
  1. Stomorgyl market audit2026
  2. EU SPC2026
  3. Same-combination stewardship label2025
  4. WSAVA dental guideline2026
  5. AAHA dental guideline2019
  6. AAFP AAHA stewardship2022
  7. Canine dental biofilm study2022
  8. Canine neurotoxicity series2018
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Spiramycin150000 IU Metronidazole25 mg
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
Merial
Manufacturer (register)
Merial, France
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 152, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტომორგილი 2
№ 215-11
Verified on: 19 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
1 tablet per 2 kg
Give one tablet per 2 kg body weight once daily for 5-10 days. Each tablet contains spiramycin 150000 IU and metronidazole 25 mg. Do not combine with another macrolide antibiotic. Massive overdose may cause tremor, spasm or ataxia; discontinue treatment. Pregnancy advice differs between national product documents, so verify the current Georgian leaflet and use only on the responsible veterinarian's assessment. The bound source does not establish tablet subdivision; a calculated fraction therefore may not be deliverable.
 Cat Any weight By mouth once daily for 5-10 days
EU SPC
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Stomorgyl 2 tablets for dogs and cats - Product Information
EU Union Product Database, 2026
1 tablet per 2 kg
Give one tablet per 2 kg body weight once daily for 5-10 days. Each tablet contains spiramycin 150000 IU and metronidazole 25 mg. Do not combine with another macrolide antibiotic. Massive overdose may cause tremor, spasm or ataxia; discontinue treatment. Pregnancy advice differs between national product documents, so verify the current Georgian leaflet and use only on the responsible veterinarian's assessment. The bound source does not establish tablet subdivision; a calculated fraction therefore may not be deliverable.
 Dog Any weight By mouth once daily for 5-10 days
EU SPC
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Stomorgyl 2 tablets for dogs and cats - Product Information
EU Union Product Database, 2026
Active substance doses, with sources
Active substance Metronidazole
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
25 mg/kg Dog, Cat Bacterial Infection By mouth 2 times daily
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Metrobactin 250 mg tablets for dogs and cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Spiramycin: No dose supported by a publicly verifiable source yet

Known Contraindications

  • Critical Metronidazole
    Do not use in cases of hepatic disorders.
    Sources: VMD SPC · VMD
  • Critical Metronidazole
    Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
    Sources: VMD SPC · VMD
  • Critical Metronidazole
    In dogs, high doses can cause neurotoxicity: tremor, muscle spasms, ataxia and even seizures, especially after a long course. The risk rises when the recommended dose or treatment length is exceeded. If neurological signs appear, stop metronidazole and treat the signs.
    Sources: VMD SPC · VMD · MSD Vet Manual
  • Warning Metronidazole
    Studies in laboratory animals have shown inconsistent results with regard to teratogenic/embryotoxic effects of metronidazole. Therefore, use of this veterinary medicinal product during pregnancy is not recommended.
    Sources: VMD SPC · VMD
  • Warning Metronidazole
    Metronidazole is excreted in milk and use during lactation is therefore not recommended.
    Sources: VMD SPC · VMD
  • Warning Metronidazole
    tremors, muscle spasms, ataxia, and even convulsions
    Sources: MSD Vet Manual
  • Warning Metronidazole (Cat)
    Metronidazole in cats: neurotoxicity (ataxia, altered mentation, tremors, seizures) is reported with high doses and long courses (58 mg/kg a day for 6 months; 111-222 mg/kg a day; 73.5-147 mg/kg a day). Keep to the label dose and duration; stop the drug at the first neurological sign.

Known Drug Interactions

  • Major warning Metronidazole + Phenobarbital
    Phenobarbital may increase hepatic metabolism of metronidazole resulting in decreased serum concentration of metronidazole.
    Recommendation: Metronidazole may be less effective than expected in a patient receiving phenobarbital. Monitor clinical response.
    Sources: VMD SPC · VMD

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 20 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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