1 form: tablet. No registration in force in Georgia.
Forms and doses0 of 1 in force in Georgia
The dose from the product's label, by species and weight. Check the label of the pack you use.
Form
Dose
Frequency
Georgia
100 mg, Tablet
10 mg/kg
Human medicine; extra-label in dogs and cats. Each tablet contains 100 mg doxycycline as doxycycline monohydrate. The current official SmPC requires dispersion of the whole tablet in at least 50 ml water, states that the score line is aesthetic rather than an equal-dose division, and explicitly says this presentation cannot provide a dose below 100 mg. Use another validated doxycycline presentation when the calculated veterinary dose does not reasonably match a whole 100 mg unit; never dry-pill a cat.
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
DogVeterinarian-directed treatment of doxycycline-susceptible bacterial infections when oral doxycycline is appropriate and the whole 100 mg dose unit fits the patient
6.9/10
Situational / acceptable
CatVeterinarian-directed treatment of doxycycline-susceptible bacterial infections when oral doxycycline is appropriate and the whole 100 mg dose unit fits the patient
Human medicine; extra-label in dogs and cats. Each tablet contains 100 mg doxycycline as doxycycline monohydrate. The current official SmPC requires dispersion of the whole tablet in at least 50 ml water, states that the score line is aesthetic rather than an equal-dose division, and explicitly says this presentation cannot provide a dose below 100 mg. Use another validated doxycycline presentation when the calculated veterinary dose does not reasonably match a whole 100 mg unit; never dry-pill a cat.
administration of doxycycline hyclate tablets has been associated with oesophageal erosion.
Sources: VMD SPC · VMD · ISCAID · JVIM
Critical
Do not use in animals with renal or hepatic insufficiency. Special warnings: None.
Sources: VMD SPC · VMD
Critical
Product labels differ: some contraindicate doxycycline in hepatic insufficiency, while others advise special caution and monitoring because liver-enzyme increases have been reported. Follow the label of the selected product and monitor hepatic function.
Sources: Product label
Critical
Do not use doxycycline tablets in animals with vomiting or dysphagia when the product label lists these conditions as contraindications. Other labels advise caution because impaired swallowing or vomiting increases the risk of a tablet lodging in the oesophagus.
Sources: VMD SPC · VMD
Critical
Do not use doxycycline in puppies or kittens before tooth-enamel formation is complete when the product label lists this as a contraindication. Doxycycline is less likely than other tetracyclines to cause tooth abnormalities because it binds calcium less strongly, but the labelled restriction still applies.
Sources: VMD SPC · VMD
Warning
Tetracyclines as a class can retard foetal skeletal development (fully reversible) The safety of the veterinary medicinal product has not been established during pregnancy
Sources: VMD
Warning
The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
Sources: VMD
Warning
Do not use in animals with known photosensitivity. During treatment, avoid prolonged intense sunlight, particularly in light-coloured or sparsely haired animals, because photosensitivity and photodermatitis may occur.
Sources: VMD SPC · VMD
Warning(Cat)
Doxycycline tablets and capsules can lodge in the cat oesophagus and cause oesophagitis and stricture (regurgitation, at varying times after the course). Follow every tablet or capsule with a water bolus or food.
Do not combine enrofloxacin with antimicrobials that act antagonistically to quinolones, including macrolides, tetracyclines such as doxycycline, and phenicols such as chloramphenicol.
Recommendation: Do not administer concurrently. Based on susceptibility testing, choose either a bactericidal fluoroquinolone or a bacteriostatic tetracycline.
Phenobarbital, phenytoin, carbamazepine, and other enzyme-inducing antiepileptic drugs can shorten the half-life of doxycycline and reduce its antibacterial exposure. Standard doxycycline dosing may therefore be subtherapeutic.
Recommendation: If the patient receives phenobarbital and doxycycline is essential, the standard 10 mg/kg dose may be inadequate; monitor clinical response closely. Alternatively, choose an antibiotic from another class based on susceptibility testing.
In dogs, concurrent administration of sucralfate suspension reduced doxycycline AUC from 36.0 to 7.2 h·mcg/mL (relative bioavailability 20%). No interaction was detected with sucralfate tablets because tablet fragments were visible in faeces, indicating that the tablets did not disintegrate and were not effective.
Recommendation: Separate administration by 2 hours: give doxycycline first and sucralfate 2 hours later. With this schedule, bioavailability is 74% and is not statistically different from doxycycline alone.
Sources: JVPT
Related products
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