Enroxil Flavour

Important safety and use flags

• Scope boundary: this is one assessment of the complete authorised susceptible-infection dog scope. It does not endorse prophylaxis, undiagnosed non-bacterial disease, every listed organism without susceptibility, cats or another enrofloxacin strength/formulation.
• Stewardship hard stop: fluoroquinolones are EMA AMEG Category B (Restrict). Prefer an effective Category D/C or narrower option; use culture/susceptibility whenever possible and document why enrofloxacin is the justified choice.
• Do not use in dogs under one year or exceptionally large breeds under 18 months: articular cartilage can be affected during rapid growth. Joint-cartilage disorder has an undetermined frequency.
• Do not use in dogs with seizure disorders because CNS stimulation can occur. Stop and reassess neurologic or behavioural change; overdose can cause GI and CNS signs and has no specific antidote.
• Use caution in severe renal or hepatic impairment and do not exceed 5 mg/kg/day. Weigh accurately and reassess exposure, response and organ function where clinically indicated.
• Very rare anorexia and vomiting are reported. Reassess persistent GI signs, treatment failure, superinfection or clinical deterioration; source control and diagnosis matter more than blind dose escalation.
• Do not combine with tetracyclines, phenicols or macrolides because of potential antagonism. Review oral anticoagulants and theophylline; separate or otherwise manage magnesium/aluminium products because absorption may be delayed.
• Exact dose: 5 mg/kg/day PO for 5-10 days, once daily or the daily amount divided twice, with or without food. The 50 mg tablet equals 10 kg and validates halves only; do not invent quarters, crush-derived doses or the US 5-20 mg/kg range.
• Enrofloxacin passes into milk; use during lactation only after veterinary benefit-risk assessment. The current exact SPC provides no separate pregnancy assurance, so do not infer pregnancy safety.
• Return a half-tablet to the opened blister and use within 24 hours. Wash hands, avoid contact after known quinolone hypersensitivity and seek medical advice after accidental ingestion.