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Product

DIRONET 200

Pyrantel + Praziquantel + Ivermectin · AVZ

1 form: tablet. In force in Georgia: 1 of 1 (veterinary register).

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Form Species Weight Dose Frequency Georgia
60/20/0.024 mg tablets, Tablet · Cat 0.5 kg and over Cat 0.5 kg and over 1 tablet per 4 kg
Cats and kittens at least 3 weeks and 0.5 kg. GI nematodes/cestodes: once; routine deworming quarterly and before vaccination. Microfilaria reduction: once monthly. Heartworm prevention: monthly during mosquito season, beginning before and ending one month after exposure. Do not combine with another anthelmintic.
· single morning dose; prevention schedule depends on indication
single morning dose; prevention schedule depends on indication Georgia Yes, veterinary
In force until 06 Sep 2029
Veterinary (National Food Agency)
In the register: დირონეტი® 200
№ 000694
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

DIRONET 200 60/20/0.024 mg tablets, Tablet

N10 for cats and kittens
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Cat
5.4/10
Weak evidence support
vetman assessment

DIRONET 200

60/20/0.024 mg tablets, N10 for cats and kittens
Assessed clinical scopeCat · Full cat label from 3 weeks and 0.5 kg: treatment of gastrointestinal roundworms and tapeworms, plus monthly microfilaria reduction and seasonal heartworm prevention with ivermectin · By mouth
Care settingVeterinary-directed deworming and seasonal heartworm prevention of a weighed cat, given with the morning feed
vetman score 5.4/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 000694 · Verified on 21 Oct 2026

A weak option: a sensible feline combination, but a species conflict between register and label and manufacturer-only evidence keep it below EU-authorised cat dewormers.

Regulatory and scientific credibility4.0/10

The current AVZ instruction describes a cat-only product, while the Georgian register entry (000694, valid to 2029) lists dogs; no EU, UK or US authorisation was documented in the reviewed evidence and no product-specific study.

Clinical efficacy6.0/10

Praziquantel and pyrantel are well supported against feline tapeworms and roundworms, and low-dose monthly ivermectin is an established feline heartworm preventive class; product-level dose evidence and bioequivalence are not public.

Safety and tolerability6.0/10

Ivermectin at preventive doses is well tolerated in cats, but the label bans pregnancy, lactation and other anthelmintics, and no independent safety data exist.

Clinical practicality6.0/10

One tablet with the morning feed is simple for deworming, but monthly seasonal heartworm use depends on reliable pilling of cats.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not use in pregnant or lactating queens, kittens under 3 weeks or cats under 0.5 kg, or together with another anthelmintic.
  • The Georgian register lists dogs, but the current instruction is for cats only; do not use this cat tablet in dogs.
  • Preventive ivermectin does not kill adult heartworms; in endemic areas assess the cat for existing infection, as AHS feline guidance advises, before relying on prevention.
  • Hunting cats may need tapeworm treatment more often than quarterly, as ESCCAP advises.
  • Stop and treat symptomatically if allergic signs appear.
Assessment sources
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Pyrantel60 mg/tablet Praziquantel20 mg/tablet Ivermectin0.024 mg/tablet
Formulation Type
Tablet
Administration route
By mouth
Manufacturer
AVZ · Russia
Manufacturer (register)
AVZ S-P Ltd, Russia
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 1182, 19 Oct 2026.
Registration
Georgia Yes, veterinary
In force until 06 Sep 2029
Veterinary (National Food Agency)
In the register: დირონეტი® 200
№ 000694
Verified on: 21 Oct 2026
Controlled in Georgia
Unknown
DoseSpeciesWeightRouteFrequencySource
1 tablet per 4 kg
Cats and kittens at least 3 weeks and 0.5 kg. GI nematodes/cestodes: once; routine deworming quarterly and before vaccination. Microfilaria reduction: once monthly. Heartworm prevention: monthly during mosquito season, beginning before and ending one month after exposure. Do not combine with another anthelmintic.
Cat 0.5 kg and over By mouth single morning dose; prevention schedule depends on indication
AVZ DIRONET 200
Manufacturer material
Information published by the maker or a seller, such as a datasheet or product page. A medicines regulator has not necessarily reviewed it.
DIRONET 200 for cats and kittens - official instruction
Official manufacturer instruction, 2026
Active substance doses, with sources
Active substance Pyrantel
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
14.4 mg/kg Dog Maintenance By mouth once
VMD SPC 2022
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Krka Multiwormer 50/144/150 mg tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2022
20 mg/kg Cat Maintenance By mouth once
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Krka Wormer 230 mg/20 mg film-coated tablets for cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024
Active substance Praziquantel
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
5 mg/kg Dog, Cat Maintenance By mouth once
VMD SPC 2022
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Krka Multiwormer 50/144/150 mg tablets for dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2022
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Krka Wormer 230 mg/20 mg film-coated tablets for cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024

Ivermectin: No dose supported by a publicly verifiable source yet

Known Contraindications

  • Critical Praziquantel
    Do not use in cases of known hypersensitivity to the active substances or to any of the excipients.
    Sources: VMD SPC · VMD
  • Critical Pyrantel (Cat)
    Do not use in kittens less than 6 weeks of age.
    Sources: VMD SPC · VMD
  • Warning Pyrantel (Cat)
    The safety of the veterinary medicinal product has not been established during pregnancy. The product should not be used during pregnancy but may be used during lactation.
    Sources: VMD SPC · VMD

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.