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Seresto

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Imidacloprid + Flumethrin · KVP Pharma + Veterinar Produkte GmbH

2 forms: topical (unspecified). In force in Georgia: 2 of 2 (veterinary register).

Forms and doses2 of 2 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
1.25 g + 0.56 g, Topical (unspecified) · Cat Any weight Cat Any weight 1 collar
Fit one 38 cm collar continuously around the cat's neck for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat kittens under 10 weeks. Use during pregnancy or lactation is not recommended. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 · continuous wear for up to 8 months		 continuous wear for up to 8 months Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ფორესტო 1.25 გ + 0.56 გ საყელო 8 კგ-მდე ძაღლებისა და კატებისათვის
№ 157-11
Verified on: 21 Oct 2026
1.25 g + 0.56 g, Topical (unspecified) · Dog up to 8 kg Dog up to 8 kg 1 collar
Fit one 38 cm collar continuously around the neck of a dog up to and including 8 kg for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat puppies under 7 weeks. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 · continuous wear for up to 8 months		 continuous wear for up to 8 months Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ფორესტო 1.25 გ + 0.56 გ საყელო 8 კგ-მდე ძაღლებისა და კატებისათვის
№ 157-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Seresto 1.25 g + 0.56 g, Topical (unspecified)

imidacloprid 1.25 g + flumethrin 0.56 g, collar 38 cm for cats and dogs up to 8 kg
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full canine label: 7-8 month flea and tick control, tick repellency, flea-larval and biting-louse control, and labelled indirect reduction of selected pathogen transmission
8.4/10
Very good
vetman assessment

Seresto

1.25 g + 0.56 g, imidacloprid 1.25 g + flumethrin 0.56 g, collar 38 cm for cats and dogs up to 8 kg
Assessed clinical scopeDog · Full canine label: 7-8 month flea and tick control, tick repellency, flea-larval and biting-louse control, and labelled indirect reduction of selected pathogen transmission · On the skin
Care settingContinuous collar wear after exact species/weight selection, correct two-finger fitting and regular skin, fit and release-mechanism checks
vetman score 8.4/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 157-11 · Verified on 21 Oct 2026

A highly effective and unusually convenient long-duration canine ectoparasite option with strong direct evidence. Its score is moderated by collar-mechanics risk and pharmacovigilance signals that require correct fitting, monitoring and prompt removal if symptoms occur.

Regulatory and scientific credibility9.0/10

The exact collars are currently registered in Georgia and retain current UK VMD product information, long regulatory histories and substantial product-specific clinical and pharmacovigilance evidence.

Clinical efficacy9.0/10

Large controlled and multicentre field programmes show sustained high flea and tick efficacy over 7-8 months, repellent tick activity and species-specific ancillary benefits; protection is not absolute and may begin more slowly against an established tick burden.

Safety and tolerability7.0/10

Field trials found mainly minor local reactions, but current labels and the EPA incident review require active monitoring for skin, gastrointestinal or neurologic signs and immediate collar removal if adverse effects occur. Mechanical entrapment, choking or trauma is a distinct collar risk; pregnancy/lactation use is not recommended.

Clinical practicality9.0/10

One correctly fitted, water-resistant collar provides continuous long-duration protection with no monthly redosing, but fit, skin and release function must be checked, especially in growing or outdoor animals.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Fit to allow two fingers beneath the collar and check frequently. Remove immediately if the collar catches, breathing or swallowing is affected, or any adverse reaction occurs; verify that the release mechanism is free to function.
  • During the first days, monitor for pruritus, erythema, hair loss or other local reaction; also watch for gastrointestinal or neurologic signs. Remove the collar and seek veterinary advice if clinically relevant signs occur.
  • Use the exact collar for species and weight: the 70 cm collar is only for dogs over 8 kg; the 38 cm collar is for cats or dogs up to 8 kg. Do not treat puppies under 7 weeks or kittens under 10 weeks.
  • Use during pregnancy or lactation is not recommended. Do not use in known hypersensitivity to either active substance or an excipient.
  • The collar reduces tick attachment and selected pathogen transmission but does not provide absolute protection; attached ticks may still be found and disease cannot be completely excluded.
  • Prevent chewing or ingestion of the collar, wash hands after fitting and keep the pouch, remnants and collar away from children and watercourses.
Assessment sources
  1. VMD Seresto dogs ≤8 kg 20262026
  2. Seresto European field studies2012
  3. Seresto canine controlled studies2012
  4. EPA Seresto incident review2023
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Full feline label: 7-8 month flea and tick control, tick repellency, flea-larval suppression and labelled indirect reduction of selected pathogen transmission
8.3/10
Very good
vetman assessment

Seresto

1.25 g + 0.56 g, imidacloprid 1.25 g + flumethrin 0.56 g, collar 38 cm for cats and dogs up to 8 kg
Assessed clinical scopeCat · Full feline label: 7-8 month flea and tick control, tick repellency, flea-larval suppression and labelled indirect reduction of selected pathogen transmission · On the skin
Care settingContinuous collar wear after exact species/weight selection, correct two-finger fitting and regular skin, fit and release-mechanism checks
vetman score 8.3/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 157-11 · Verified on 21 Oct 2026

A highly effective and unusually convenient long-duration feline ectoparasite option with strong direct evidence. Its score is moderated by real collar-mechanics risk, pharmacovigilance signals requiring prompt removal if symptoms occur, and lack of recommended pregnancy/lactation use.

Regulatory and scientific credibility9.0/10

The exact collars are currently registered in Georgia and retain current UK VMD product information, long regulatory histories and substantial product-specific clinical and pharmacovigilance evidence.

Clinical efficacy9.0/10

Large controlled and multicentre field programmes show sustained high flea and tick efficacy over 7-8 months, repellent tick activity and species-specific ancillary benefits; protection is not absolute and may begin more slowly against an established tick burden.

Safety and tolerability6.5/10

Field trials found mainly minor local reactions, but current labels and the EPA incident review require active monitoring for skin, gastrointestinal or neurologic signs and immediate collar removal if adverse effects occur. Mechanical entrapment, choking or trauma is a distinct collar risk; pregnancy/lactation use is not recommended.

Clinical practicality9.0/10

One correctly fitted, water-resistant collar provides continuous long-duration protection with no monthly redosing, but fit, skin and release function must be checked, especially in growing or outdoor animals.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Fit to allow two fingers beneath the collar and check frequently. Remove immediately if the collar catches, breathing or swallowing is affected, or any adverse reaction occurs; verify that the release mechanism is free to function.
  • During the first days, monitor for pruritus, erythema, hair loss or other local reaction; also watch for gastrointestinal or neurologic signs. Remove the collar and seek veterinary advice if clinically relevant signs occur.
  • Use the exact collar for species and weight: the 70 cm collar is only for dogs over 8 kg; the 38 cm collar is for cats or dogs up to 8 kg. Do not treat puppies under 7 weeks or kittens under 10 weeks.
  • Use during pregnancy or lactation is not recommended. Do not use in known hypersensitivity to either active substance or an excipient.
  • The collar reduces tick attachment and selected pathogen transmission but does not provide absolute protection; attached ticks may still be found and disease cannot be completely excluded.
  • Prevent chewing or ingestion of the collar, wash hands after fitting and keep the pouch, remnants and collar away from children and watercourses.
Assessment sources
  1. VMD SPC 20252025
  2. Seresto European field studies2012
  3. EPA Seresto incident review2023
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Imidacloprid1.25 g Flumethrin0.56 g
Formulation Type
Topical (unspecified)
Administration route
On the skin
Manufacturer (register)
KVP Pharma + Veterinar Produkte GmbH, Germany
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 278, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ფორესტო 1.25 გ + 0.56 გ საყელო 8 კგ-მდე ძაღლებისა და კატებისათვის
№ 157-11
Verified on: 21 Oct 2026
 EU Yes, veterinary
Verified on: 15 Oct 2026
 UK Yes, veterinary
Verified on: 15 Oct 2026
 US Yes, veterinary
№ EPA 11556-155
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 collar
Fit one 38 cm collar continuously around the cat's neck for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat kittens under 10 weeks. Use during pregnancy or lactation is not recommended. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 Cat Any weight On the skin continuous wear for up to 8 months
VMD Seresto cats 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Seresto 1.25 g + 0.56 g medicated collar for cats - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
1 collar
Fit one 38 cm collar continuously around the neck of a dog up to and including 8 kg for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat puppies under 7 weeks. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 Dog up to 8 kg On the skin continuous wear for up to 8 months
VMD Seresto dogs ≤8 kg 2026
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Seresto 1.25 g + 0.56 g medicated collar for dogs up to 8 kg - package leaflet
UK Veterinary Medicines Directorate, 2026
4.50 g + 2.03 g, Topical (unspecified) · Dog over 8 kg Dog over 8 kg 1 collar
Fit one 70 cm collar continuously around the neck of a dog over 8 kg for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat puppies under 7 weeks. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 · continuous wear for up to 8 months		 continuous wear for up to 8 months Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ფორესტო 4.50 გ + 2.03 გ საყელო 8 კგ-ზე მძიმე ძაღლებისათვის
№ 156-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Seresto 4.50 g + 2.03 g, Topical (unspecified)

imidacloprid 4.5 g + flumethrin 2.03 g, collar 70 cm for dogs over 8 kg
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
8.4/10
Very good
vetman assessment

Seresto

4.50 g + 2.03 g, imidacloprid 4.5 g + flumethrin 2.03 g, collar 70 cm for dogs over 8 kg
Assessed clinical scopeDog · Full canine label: 7-8 month flea and tick control, tick repellency, flea-larval and biting-louse control, and labelled indirect reduction of selected pathogen transmission · On the skin
Care settingContinuous collar wear after exact species/weight selection, correct two-finger fitting and regular skin, fit and release-mechanism checks
vetman score 8.4/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 156-11 · Verified on 21 Oct 2026

A highly effective and unusually convenient long-duration canine ectoparasite option with strong direct evidence. Its score is moderated by collar-mechanics risk and pharmacovigilance signals that require correct fitting, monitoring and prompt removal if symptoms occur.

Regulatory and scientific credibility9.0/10

The exact collars are currently registered in Georgia and retain current UK VMD product information, long regulatory histories and substantial product-specific clinical and pharmacovigilance evidence.

Clinical efficacy9.0/10

Large controlled and multicentre field programmes show sustained high flea and tick efficacy over 7-8 months, repellent tick activity and species-specific ancillary benefits; protection is not absolute and may begin more slowly against an established tick burden.

Safety and tolerability7.0/10

Field trials found mainly minor local reactions, but current labels and the EPA incident review require active monitoring for skin, gastrointestinal or neurologic signs and immediate collar removal if adverse effects occur. Mechanical entrapment, choking or trauma is a distinct collar risk; pregnancy/lactation use is not recommended.

Clinical practicality9.0/10

One correctly fitted, water-resistant collar provides continuous long-duration protection with no monthly redosing, but fit, skin and release function must be checked, especially in growing or outdoor animals.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Fit to allow two fingers beneath the collar and check frequently. Remove immediately if the collar catches, breathing or swallowing is affected, or any adverse reaction occurs; verify that the release mechanism is free to function.
  • During the first days, monitor for pruritus, erythema, hair loss or other local reaction; also watch for gastrointestinal or neurologic signs. Remove the collar and seek veterinary advice if clinically relevant signs occur.
  • Use the exact collar for species and weight: the 70 cm collar is only for dogs over 8 kg; the 38 cm collar is for cats or dogs up to 8 kg. Do not treat puppies under 7 weeks or kittens under 10 weeks.
  • Use during pregnancy or lactation is not recommended. Do not use in known hypersensitivity to either active substance or an excipient.
  • The collar reduces tick attachment and selected pathogen transmission but does not provide absolute protection; attached ticks may still be found and disease cannot be completely excluded.
  • Prevent chewing or ingestion of the collar, wash hands after fitting and keep the pouch, remnants and collar away from children and watercourses.
Assessment sources
  1. VMD SPC 20252025
  2. Seresto European field studies2012
  3. Seresto canine controlled studies2012
  4. EPA Seresto incident review2023
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Imidacloprid4.5 g Flumethrin2.03 g
Formulation Type
Topical (unspecified)
Administration route
On the skin
Manufacturer (register)
KVP Pharma + Veterinar Produkte GmbH, Germany
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 277, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ფორესტო 4.50 გ + 2.03 გ საყელო 8 კგ-ზე მძიმე ძაღლებისათვის
№ 156-11
Verified on: 21 Oct 2026
 EU Yes, veterinary
Verified on: 15 Oct 2026
 UK Yes, veterinary
Verified on: 15 Oct 2026
 US Yes, veterinary
№ EPA 11556-155
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 collar
Fit one 70 cm collar continuously around the neck of a dog over 8 kg for up to 8 months. Leave room for two fingers and do not allow chewing. Do not treat puppies under 7 weeks. Ticks already present may remain attached for up to 48 hours and transmission of infection cannot be completely excluded. Remove the collar if significant application-site, neurological or hypersensitivity signs occur.
 Dog over 8 kg On the skin continuous wear for up to 8 months
VMD Seresto >8 kg 2025
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
Seresto 4.50 g + 2.03 g medicated collar for dogs over 8 kg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
Active substance doses, with sources
Active substance Imidacloprid
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
10–25 mg/kg Dog Maintenance On the skin monthly
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Advocate 400 mg + 100 mg spot-on solution for extra-large dogs (> 25-40 kg) - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
10–20 mg/kg Cat Maintenance On the skin monthly
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Advocate 40 mg + 4 mg spot-on solution for small cats (<= 4 kg) and ferrets - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Flumethrin: No dose supported by a publicly verifiable source yet

Known Contraindications

  • Critical Flumethrin
    Do not use in cases of hypersensitivity to the active substances or to any of the excipients. Nepoužívat v případech přecitlivělosti na léčivé látky nebo na některou z pomocných látek.
    Sources: VMD SPC · USKVBL PIL · VMD
  • Critical Flumethrin (Dog)
    Do not treat puppies less than 7 weeks of age. Nepoužívat u štěňat do 3 měsíců
    Sources: VMD SPC · USKVBL PIL · VMD
  • Critical Flumethrin (Cat)
    Do not treat kittens less than 10 weeks of age.
    Sources: VMD SPC · VMD
  • Warning Flumethrin
    The safety of the veterinary medicinal product has not been established in target animals during pregnancy and lactation. Pregnancy and lactation: The use is not recommended during pregnancy and lactation. Laboratory studies with either flumethrin or imidacloprid in rats and rabbits showed no teratogenic, or foetotoxic effects. Nebyla stanovena bezpečnost veterinárního léčivého přípravku pro použití během březosti.
    Sources: VMD SPC · USKVBL PIL · VMD
  • Warning Flumethrin
    The use is not recommended during pregnancy and lactation.
    Sources: VMD SPC · VMD
  • Caution Flumethrin
    Organophosphates slow or prevent pyrethroid breakdown and can increase flumethrin toxicity: avoid combining with organophosphate ectoparasiticides.
  • Critical Imidacloprid
    Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
    Sources: VMD SPC · VMD

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

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Professional reference for veterinary professionals. Not advertising and not a substitute for the product label/SPC.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 21 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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