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Propoxur · Farma Vet Ltd, Farma Vet OOD

2 forms: powder, topical (unspecified). In force in Georgia: 2 of 2 (veterinary register).

Forms and doses2 of 2 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Dose Frequency Georgia
1% cutaneous powder, Powder - No label dose in the reference yet - Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბრეიქ პრო პუდრი
№ 147-11
Verified on: 21 Oct 2026
Details: pack, label wording, sources, registration

Break Pro 1% cutaneous powder, Powder

40 g for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Full dog label: treatment and control of flea, louse and tick infestation with a propoxur 1% powder dusted over the coat once or twice weekly
5.6/10
Weak evidence support
vetman assessment

Break Pro

1% cutaneous powder, 40 g for dogs and cats
Assessed clinical scopeDog · Full dog label: treatment and control of flea, louse and tick infestation with a propoxur 1% powder dusted over the coat once or twice weekly · On the skin
Care settingOwner or clinic dusting of a healthy dog with gloves, dust mask and eye protection, alongside environmental control
vetman score 5.6/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 147-11 · Verified on 21 Oct 2026

A weak option: an EU-authorised but dated carbamate powder with short action and owner exposure. Longer-acting spot-ons, collars or isoxazolines are easier and better supported.

Regulatory and scientific credibility6.5/10

The product has a current Bulgarian national authorisation with an SPC in the EU Union Product Database and is registered in Georgia for dogs (147-11); no independent product study was found.

Clinical efficacy5.0/10

Propoxur is a long-used carbamate with flea and tick activity, but a powder gives short protection, has no measured dose and needs weekly repeats; modern guidelines favour longer-acting classes.

Safety and tolerability5.5/10

The SPC allows use in pregnancy and lactation, but propoxur inhibits cholinesterase: high oral exposure causes cholinergic signs, and the dust exposes owners, children and other pets.

Clinical practicality5.0/10

Dusting the whole coat once or twice weekly for several weeks with gloves, mask and eye protection is laborious and the endpoint is qualitative.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Do not combine with organophosphates or other cholinesterase inhibitors; atropine sulfate is the antidote for cholinergic signs.
  • Do not use on damaged skin, in sick or convalescent dogs, or with ingredient hypersensitivity.
  • Watch for salivation, vomiting, tremor or miosis after grooming or ingestion of powder.
  • Avoid eyes, nose and mouth; wear rubber gloves, a dust mask and eye protection and keep children away.
  • Hazardous to fish and aquatic organisms; treat all in-contact animals and the environment.
Assessment sources
  1. EU UPD SPC 20242024
  2. Georgia NFA register 20262026
  3. ESCCAP ectoparasite guideline2024
  4. MSD Vet Manual 20242024
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat EU SPC cat use: treatment and control of flea, louse and tick infestation with a propoxur 1% powder; the Georgian registration lists dogs only
5.1/10
Weak evidence support
vetman assessment

Break Pro

1% cutaneous powder, 40 g for dogs and cats
Assessed clinical scopeCat · EU SPC cat use: treatment and control of flea, louse and tick infestation with a propoxur 1% powder; the Georgian registration lists dogs only · On the skin
Care settingVeterinary-directed use only, where a safer cat-authorised product is not available
vetman score 5.1/10 Weak evidence support
Evidence confidence: Low Georgia: Yes, veterinary · № 147-11 · Verified on 21 Oct 2026

A weak option for cats: a carbamate powder outside the Georgian dog-only registration, with grooming-related toxicity risk. Prefer a cat-authorised fipronil, selamectin or isoxazoline product.

Regulatory and scientific credibility6.0/10

The Bulgarian SPC in the EU database covers cats, but the Georgian registration (147-11) lists dogs only, so cat use in Georgia is outside the local registration.

Clinical efficacy5.0/10

Propoxur has flea and tick activity, but a powder gives short protection, has no measured dose and needs repeated dusting.

Safety and tolerability4.5/10

Cats groom off and swallow powder and are more sensitive than dogs to cholinesterase inhibitors, so cholinergic toxicity is a real risk.

Clinical practicality5.0/10

Repeated whole-coat dusting with gloves, mask and eye protection is difficult in cats.

Full-course cost-effectiveness-

No verified current Georgian price or patient-adjusted course cost was found; foreign prices were not substituted.

Important safety and use flags

  • Carbamate in a cat: watch for salivation, vomiting, tremor, miosis or weakness; atropine sulfate is the antidote.
  • Do not combine with organophosphates, other carbamates or cholinesterase-inhibiting collars.
  • The Georgian registration lists dogs only; cat use relies on the EU SPC.
  • Do not use on damaged skin, in sick or convalescent cats, or with ingredient hypersensitivity.
  • Wear gloves, a dust mask and eye protection; hazardous to fish and aquatic organisms.
Assessment sources
  1. EU UPD SPC 20242024
  2. Georgia NFA register 20262026
  3. ESCCAP ectoparasite guideline2024
  4. MSD Vet Manual 20242024
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Propoxur10 mg/g
Formulation Type
Powder
Administration route
TOPICAL
Manufacturer
Farma Vet Ltd
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბრეიქ პრო პუდრი
№ 147-11
Verified on: 21 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
10 mg/ml medicated shampoo, Topical (unspecified) · Cat Cat 1–2 ml/kg
Apply 1-2 ml/kg to the wet coat. Massage to a rich foam for 3-5 minutes, rinse thoroughly and dry. Cats are more sensitive to carbamates: do not exceed the labelled amount. Avoid eyes, ears, nose and mouth; wear gloves. Do not use on damaged skin or in sick or convalescent animals.
 · single shampoo treatment; repeat only on veterinary direction		 single shampoo treatment; repeat only on veterinary direction Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბრეიქ პრო შამპუნი
№ 144-11
Verified on: 23 Oct 2026
10 mg/ml medicated shampoo, Topical (unspecified) · Dog Dog 1–2 ml/kg
Apply to the wet coat: short-haired dogs 1 ml/kg; long-haired dogs 1-2 ml/kg, maximum 20 ml total. Distribute especially to axillae, hind limbs, back, nape, scapular area and tail, massage to a rich foam for 3-5 minutes, rinse thoroughly and towel-dry. Avoid eyes, ears, nose and mouth; wear gloves. Do not use on damaged skin or in sick or convalescent animals.
 · single shampoo treatment; repeat only on veterinary direction		 single shampoo treatment; repeat only on veterinary direction Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბრეიქ პრო შამპუნი
№ 144-11
Verified on: 23 Oct 2026
Details: pack, label wording, sources, registration

BREAK PRO 10 mg/ml medicated shampoo, Topical (unspecified)

250 ml for dogs and cats
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog Complete authorised canine role: rinse-off control of external parasites with propoxur 10 mg/ml, without an invented named-parasite spectrum or residual interval
6.4/10
Situational / acceptable
vetman assessment

BREAK PRO

10 mg/ml medicated shampoo, 250 ml for dogs and cats
Assessed clinical scopeDog · Complete authorised canine role: rinse-off control of external parasites with propoxur 10 mg/ml, without an invented named-parasite spectrum or residual interval · On the skin
Care settingAt-home rinse-off ectoparasite treatment selected by a veterinarian, with accurate weight/hair-length dosing, 3-5-minute contact, prevention of licking/exposure, household parasite control and reassessment before repetition
vetman score 6.4/10 Situational / acceptable
Evidence confidence: Medium Georgia: Yes, veterinary · № 144-11 · Verified on 23 Oct 2026

A transparent authorised rinse-off propoxur option for selected acute canine ectoparasite control, but evidence is old and formulation-mismatched, the public label gives no named spectrum or residual protection, and carbamate exposure plus environmental reinfestation prevent it from being a strong standalone programme.

Regulatory and scientific credibility8.0/10

The exact strength, dog/cat dose, contraindications, reproduction, overdose, storage and operator precautions are transparent under current Georgian and valid Bulgarian/EU national authorisations. Public exact-product outcome and broad pharmacovigilance data remain limited, and the product is not registered in GB or the US.

Clinical efficacy5.5/10

Propoxur has coherent rapid adulticidal activity and an old controlled 0.1% shampoo study cleared fleas from treated dogs, but exact BREAK PRO is 1%, has no public controlled outcome trial, and its broad external-parasite label names neither targets nor residual duration. A rinse-off treatment is not a complete reinfestation-prevention programme.

Safety and tolerability6.0/10

The exact label permits pregnancy/lactation, reports only unquantified pruritus/redness in hypersensitive animals and describes tolerance above the labelled topical dose. Propoxur still inhibits cholinesterase: ingestion, damaged skin, eye/mucosal contact and operator exposure can produce serious cholinergic toxicity, while post-market frequency is not public.

Clinical practicality6.0/10

A single 3-5-minute bath and rinse is feasible at home, but weight and hair-length dosing, a 20 ml ceiling for long-haired dogs, full coat coverage, eye/ear avoidance and prevention of licking require careful handling. No labelled residual interval or repeat schedule means environmental control and a planned longer-term strategy remain necessary.

Full-course cost-effectiveness-

Current Georgian price for the exact 250 ml presentation and repeat-course cost were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete scope: the exact label says external parasites in dogs and cats but does not name parasite species or a residual-protection interval. Do not promise a specific flea/tick/lice/mite spectrum, duration or prevention of reinfestation that the public SPC does not establish.
  • Dose on wet coat: short-haired dog 1 ml/kg; long-haired dog 1-2 ml/kg, maximum 20 ml total. A single 1 ml/kg dog row without the hair-length boundary is incomplete and must not be used blindly.
  • Distribute especially to axillae, hind limbs, back, nape, scapular area and tail, massage to rich foam for 3-5 minutes, then rinse thoroughly and towel-dry. Avoid eyes, ears, nose and mouth and prevent licking throughout treatment and drying.
  • Do not use on damaged skin, in a sick or convalescent animal or with hypersensitivity. Pruritus/redness may occur in hypersensitive animals; stop, rinse and assess material irritation or systemic signs.
  • Propoxur inhibits acetylcholinesterase. Salivation, lacrimation, vomiting/diarrhoea, miosis, tremor, fasciculation, weakness, dyspnoea or seizures after ingestion or excess exposure are an emergency: decontaminate safely and obtain urgent veterinary toxicology care; atropine is the label antidote.
  • The SPC permits pregnancy and lactation and states no known interactions. This does not prove zero interaction risk: avoid unreviewed concurrent organophosphate/carbamate or other cholinesterase-inhibiting ectoparasiticides and calculate total exposure before combining products.
  • Independent shampoo evidence is old and used 0.1% propoxur, whereas exact BREAK PRO is 1%. It supports possible rapid flea knock-down only; it does not validate the exact broad label, residual duration, modern comparative efficacy or repeated-use safety.
  • A rinse-off shampoo does not treat the off-host flea population or supply a labelled sustained interval. Examine and appropriately treat all household animals, vacuum and wash bedding, address the environment and choose a continued preventive plan when risk persists.
  • Wear rubber gloves and safety glasses; avoid skin, eye, nose and mouth exposure. If exposed, rinse promptly and wash skin with soap and water. Keep children away during use and drying and prevent contamination of food, water and aquatic environments.
  • Store below 25 C in the original dry container protected from direct sunlight, mark first opening and discard after two months. Verify the exact 250 ml product, authorisation, lot and expiry; do not substitute BREAK PRO powder or a herbal shampoo with a similar name.
Assessment sources
  1. BREAK PRO GE register2026
  2. BREAK PRO exact SPC2026
  3. BREAK PRO BFSA register2026
  4. BREAK PRO manufacturer2026
  5. Propoxur dog shampoo study1988
  6. ESCCAP ectoparasite GL32026
  7. CAPC flea control2026
  8. Carbamate toxicosis2024
  9. GB VMD current database2026
  10. US EPA PPLS2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Cat Complete authorised feline role: rinse-off control of external parasites with propoxur 10 mg/ml, without an invented named-parasite spectrum or residual interval
5.9/10
Weak evidence support
vetman assessment

BREAK PRO

10 mg/ml medicated shampoo, 250 ml for dogs and cats
Assessed clinical scopeCat · Complete authorised feline role: rinse-off control of external parasites with propoxur 10 mg/ml, without an invented named-parasite spectrum or residual interval · On the skin
Care settingAt-home rinse-off ectoparasite treatment selected by a veterinarian, with accurate weight/hair-length dosing, 3-5-minute contact, prevention of licking/exposure, household parasite control and reassessment before repetition
vetman score 5.9/10 Weak evidence support
Evidence confidence: Medium Georgia: Yes, veterinary · № 144-11 · Verified on 23 Oct 2026

An authorised feline rinse-off option with a clear exact dose, but only tiny old mismatched shampoo evidence, no labelled residual protection and explicit greater feline carbamate sensitivity. Careful bathing, licking prevention, environmental control and a sustained alternative plan determine whether its narrow acute role is acceptable.

Regulatory and scientific credibility8.0/10

The exact strength, dog/cat dose, contraindications, reproduction, overdose, storage and operator precautions are transparent under current Georgian and valid Bulgarian/EU national authorisations. Public exact-product outcome and broad pharmacovigilance data remain limited, and the product is not registered in GB or the US.

Clinical efficacy5.0/10

A tiny old study of five cats given 0.1% propoxur shampoo showed rapid flea clearance but no residual effect; exact BREAK PRO is 1% and lacks a public controlled feline outcome trial. The broad label names neither targets nor residual duration, so efficacy beyond acute selected use is uncertain.

Safety and tolerability5.0/10

The exact label permits pregnancy/lactation and reports topical overdose observation, but explicitly says cats are more sensitive to carbamates. Grooming/licking, damaged skin and mucosal exposure can turn a topical bath into clinically important cholinergic exposure, and adverse-event frequency is not quantified.

Clinical practicality5.5/10

One bath avoids a prolonged dosing course, but accurately holding and fully wetting a cat, maintaining 3-5-minute contact, rinsing, drying and preventing licking can be stressful and error-prone. The missing residual interval and repeat schedule also require environmental control and a separate sustained prevention plan.

Full-course cost-effectiveness-

Current Georgian price for the exact 250 ml presentation and repeat-course cost were unavailable; price is excluded from the denominator.

Important safety and use flags

  • Complete scope: the exact label says external parasites in dogs and cats but does not name parasite species or a residual-protection interval. Do not promise a specific flea/tick/lice/mite spectrum, duration or prevention of reinfestation that the public SPC does not establish.
  • Dose on wet coat: cat 1-2 ml/kg. Cats are more sensitive to carbamates; weigh accurately and do not exceed the exact labelled quantity.
  • Distribute especially to axillae, hind limbs, back, nape, scapular area and tail, massage to rich foam for 3-5 minutes, then rinse thoroughly and towel-dry. Avoid eyes, ears, nose and mouth and prevent licking throughout treatment and drying.
  • Do not use on damaged skin, in a sick or convalescent animal or with hypersensitivity. Pruritus/redness may occur in hypersensitive animals; stop, rinse and assess material irritation or systemic signs.
  • Propoxur inhibits acetylcholinesterase. Salivation, lacrimation, vomiting/diarrhoea, miosis, tremor, fasciculation, weakness, dyspnoea or seizures after ingestion or excess exposure are an emergency: decontaminate safely and obtain urgent veterinary toxicology care; atropine is the label antidote.
  • The SPC permits pregnancy and lactation and states no known interactions. This does not prove zero interaction risk: avoid unreviewed concurrent organophosphate/carbamate or other cholinesterase-inhibiting ectoparasiticides and calculate total exposure before combining products.
  • Independent shampoo evidence is old and used 0.1% propoxur, whereas exact BREAK PRO is 1%. It supports possible rapid flea knock-down only; it does not validate the exact broad label, residual duration, modern comparative efficacy or repeated-use safety.
  • A rinse-off shampoo does not treat the off-host flea population or supply a labelled sustained interval. Examine and appropriately treat all household animals, vacuum and wash bedding, address the environment and choose a continued preventive plan when risk persists.
  • Wear rubber gloves and safety glasses; avoid skin, eye, nose and mouth exposure. If exposed, rinse promptly and wash skin with soap and water. Keep children away during use and drying and prevent contamination of food, water and aquatic environments.
  • Store below 25 C in the original dry container protected from direct sunlight, mark first opening and discard after two months. Verify the exact 250 ml product, authorisation, lot and expiry; do not substitute BREAK PRO powder or a herbal shampoo with a similar name.
Assessment sources
  1. BREAK PRO GE register2026
  2. BREAK PRO exact SPC2026
  3. BREAK PRO BFSA register2026
  4. BREAK PRO manufacturer2026
  5. Propoxur cat shampoo study1989
  6. ESCCAP ectoparasite GL32026
  7. CAPC flea control2026
  8. Carbamate toxicosis2024
  9. GB VMD current database2026
  10. US EPA PPLS2026
Assessed: 23 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Propoxur10 mg/ml
Formulation Type
Topical (unspecified)
Administration route
On the skin
Manufacturer
Farma Vet OOD
Manufacturer (register)
Farma Vet“ Ltd, Bulgaria
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 411, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ბრეიქ პრო შამპუნი
№ 144-11
Verified on: 23 Oct 2026
 EU Yes, veterinary
№ 0022-1620
Verified on: 23 Oct 2026
 UK No
Verified on: 23 Oct 2026
 US No
Verified on: 23 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
Information not fully verified Wet the coat. Cats: 1-2 ml/kg. Short-haired dogs: 1 ml/kg. Long-haired dogs: 1-2 ml/kg, maximum 20 ml total. Distribute especially to axillae, hind limbs, back, nape, scapular area and tail; massage to foam for 3-5 minutes, rinse thoroughly and towel-dry. A single treatment has no labelled residual interval; repeat only after veterinary reassessment.
DoseSpeciesWeightRouteFrequencySource
1–2 ml/kg
Apply 1-2 ml/kg to the wet coat. Massage to a rich foam for 3-5 minutes, rinse thoroughly and dry. Cats are more sensitive to carbamates: do not exceed the labelled amount. Avoid eyes, ears, nose and mouth; wear gloves. Do not use on damaged skin or in sick or convalescent animals.
 Cat Any weight On the skin single shampoo treatment; repeat only on veterinary direction
EU UPD BREAK PRO shampoo
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
BREAK PRO 10 mg/ml medicated shampoo - current official product information
EU Veterinary Medicines Information, 2026
1–2 ml/kg
Apply to the wet coat: short-haired dogs 1 ml/kg; long-haired dogs 1-2 ml/kg, maximum 20 ml total. Distribute especially to axillae, hind limbs, back, nape, scapular area and tail, massage to a rich foam for 3-5 minutes, rinse thoroughly and towel-dry. Avoid eyes, ears, nose and mouth; wear gloves. Do not use on damaged skin or in sick or convalescent animals.
 Dog Any weight On the skin single shampoo treatment; repeat only on veterinary direction
EU UPD BREAK PRO shampoo
Official product label (SPC)
Approved by a medicines regulator as part of the product's authorisation. It applies to that product as authorised there.
BREAK PRO 10 mg/ml medicated shampoo - current official product information
EU Veterinary Medicines Information, 2026

Propoxur: No dose supported by a publicly verifiable source yet

Known Contraindications

  • Critical
    Do not use the propoxur/flumethrin collar in animals with hypersensitivity to either active ingredient or any excipient.
    Sources: USKVBL PIL
  • Critical
    Do not use the propoxur collar in animals with mechanical gastrointestinal or urinary obstruction, bronchial asthma, or other pulmonary or cardiovascular disease. Carbamate poisoning can cause salivation, miosis, vomiting, and diarrhoea, especially if the collar is chewed or swallowed. Remove the collar and administer atropine intravenously as the antidote.
    Sources: USKVBL PIL
  • Critical
    Do not use the propoxur/flumethrin collar on animals with damaged skin.
    Sources: USKVBL PIL
  • Critical (Dog)
    Do not use the propoxur/flumethrin collar in puppies younger than 3 months.
    Sources: USKVBL PIL
  • Warning
    Safety of the propoxur/flumethrin collar during pregnancy has not been established. Available data for the active ingredients do not show teratogenic, fetotoxic, or maternal toxicity.
    Sources: USKVBL PIL

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 23 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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