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Top Spot On Stronger

Permethrin · Bioveta

1 form: spot-on. In force in Georgia: 1 of 1 (veterinary register).

Do not use on cats. Prevent cats from contacting or grooming a treated dog; follow the exact label for the separation period. Species safety: cats →

Forms and doses1 of 1 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
650 mg/ml, Spot-on · Cat Any weight Cat Any weight No dose for this species
Never use in cats: permethrin can be fatal to cats.
- Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ტოპ სპოტ ონ სტრონგერ 650 მგ
№ 17-11, 156-11
Verified on: 15 Oct 2026
650 mg/ml, Spot-on · Dog up to 15 kg Dog up to 15 kg 1 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
· once; repeat not sooner than 7 days
once; repeat not sooner than 7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ტოპ სპოტ ონ სტრონგერ 650 მგ
№ 17-11, 156-11
Verified on: 15 Oct 2026
650 mg/ml, Spot-on · Dog 15–30 kg Dog 15–30 kg 2 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
· once; repeat not sooner than 7 days
once; repeat not sooner than 7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ტოპ სპოტ ონ სტრონგერ 650 მგ
№ 17-11, 156-11
Verified on: 15 Oct 2026
650 mg/ml, Spot-on · Dog over 30 kg Dog over 30 kg 3 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
· once; repeat not sooner than 7 days
once; repeat not sooner than 7 days Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ტოპ სპოტ ონ სტრონგერ 650 მგ
№ 17-11, 156-11
Verified on: 15 Oct 2026
Details: pack, label wording, sources, registration

Top Spot On Stronger 650 mg/ml, Spot-on

permethrin 650 mg/ml, spot-on solution for dogs
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Dog
7.6/10
Good
vetman assessment

Top Spot On Stronger

650 mg/ml, permethrin 650 mg/ml, spot-on solution for dogs
Assessed clinical scopeDog · Full canine label: therapeutic and preventive control of fleas and ticks, with protection against ticks for up to four weeks and fleas for up to three months · On the skin
Care settingHome spot-on use after confirming canine species, body weight and ectoparasite risk; apply one to three 1 ml applicators directly to the skin at the label-defined dorsal sites
vetman score 7.6/10 Good
Evidence confidence: Medium Georgia: Yes, veterinary · № 17-11, 156-11 · Verified on 15 Oct 2026

A credible registered single-ingredient canine permethrin spot-on with a clear weight-based regimen and useful labelled duration. It is a reasonable flea and tick option when strict cat-exposure prevention is feasible, but exact-product comparative evidence is thinner than for the best-documented modern combinations.

Regulatory and scientific credibility8.4/10

The exact 650 mg/ml product is registered in Georgia and remains valid in the EU regulatory network with a regulator-hosted exact-product SPC, clear composition, dose bands and authorisation history.

Clinical efficacy7.4/10

The label supports prolonged flea and tick control. A small controlled field study found 100% flea efficacy through day 28 with a 65% permethrin spot-on, and a broad review supports roughly four-week tick activity, but formulation-dependent variability and limited exact-product comparative evidence remain.

Safety and tolerability7.0/10

Correctly dosed canine use is generally well tolerated, with temporary application-site irritation identified by the product information and no clinical signs in the small 65% permethrin field study. The severe and potentially fatal hazard to cats makes species separation and residue control essential.

Clinical practicality7.8/10

Weight-banded one-time application is straightforward, but medium and large dogs require two or three applicators at multiple dorsal sites. Wetting or shampooing requires repeat treatment, with at least seven days between applications, and treated dogs must be separated from cats until dry.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • For dogs only. Permethrin is extremely poisonous and potentially fatal to cats; prevent direct application, grooming of the treated dog and contact until the application sites are dry, and seek urgent veterinary advice after exposure.
  • Do not use in puppies under three weeks of age or in animals hypersensitive to permethrin or an excipient.
  • Do not combine with another insecticidal ectoparasiticide unless the combination has been specifically assessed.
  • Temporary application-site irritation can occur. If it develops, rinse the dog with water and assess persistent or systemic signs.
  • Apply directly to skin at the correct number of sites: one 1 ml applicator below 15 kg, two at 15-30 kg and three above 30 kg. Do not rub in.
  • Repeat after the dog becomes soaked or is shampooed, but never sooner than seven days after the preceding application.
  • Permethrin distribution and tick efficacy vary with formulation, dose, coat and body site. The label controls ectoparasites but does not guarantee prevention of every attachment, bite or pathogen transmission.
Assessment sources
Assessed: 22 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Permethrin650 mg/ml
Formulation Type
Spot-on
Administration route
On the skin
Manufacturer
Bioveta · Czechia
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: ტოპ სპოტ ონ სტრონგერ 650 მგ
№ 17-11, 156-11
Verified on: 15 Oct 2026
EU Yes, veterinary
Verified on: 15 Oct 2026
UK No
Verified on: 15 Oct 2026
US No
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
No dose for this species
Never use in cats: permethrin can be fatal to cats.
Cat Any weight On the skin - Product label (SPC)
1 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
Dog up to 15 kg On the skin once; repeat not sooner than 7 days
EMA UPD 2022
Official product label (SPC), UPD, EU
Approved by an EU medicines regulator (published in the EU Union Product Database, UPD) as part of the product's authorisation. It applies to that product as authorised there.
TOP SPOT ON STRONGER 650 mg spot-on solution for dogs - Summary of Product Characteristics (Czech)
EU Union Product Database, 2022
2 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
Dog 15–30 kg On the skin once; repeat not sooner than 7 days
EMA UPD 2022
Official product label (SPC), UPD, EU
Approved by an EU medicines regulator (published in the EU Union Product Database, UPD) as part of the product's authorisation. It applies to that product as authorised there.
TOP SPOT ON STRONGER 650 mg spot-on solution for dogs - Summary of Product Characteristics (Czech)
EU Union Product Database, 2022
3 ml
1 ml tubes of permethrin 650 mg/ml: one tube between the shoulder blades up to 15 kg; two tubes (shoulders and tail base) at 15-30 kg; three tubes (shoulders, mid-back, tail base) above 30 kg. Protects against ticks for up to 4 weeks and fleas for up to 3 months; re-treat after soaking or shampooing, at least 7 days apart. Never in cats (toxic); not under 3 weeks of age; not with other insecticidal ectoparasiticides.
Dog over 30 kg On the skin once; repeat not sooner than 7 days
EMA UPD 2022
Official product label (SPC), UPD, EU
Approved by an EU medicines regulator (published in the EU Union Product Database, UPD) as part of the product's authorisation. It applies to that product as authorised there.
TOP SPOT ON STRONGER 650 mg spot-on solution for dogs - Summary of Product Characteristics (Czech)
EU Union Product Database, 2022
Active substance doses, with sources
Active substance Permethrin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
50 mg/kg Dog Maintenance On the skin according to the epidemiological situation
VMD SPC 2026
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Advantix 40 mg + 200 mg spot-on solution for dogs (<= 4 kg) - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2026
60 mg/kg Dog Maintenance On the skin not more often than once every 4 weeks
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Effitix 26.8 mg/240 mg spot-on solution for very small dogs - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025

Known Contraindications

  • Critical
    Do not use in cases of hypersensitivity to the active substances, or to any of the excipients.
    Sources: VMD SPC · VMD
  • Critical (Cat)
    Do not use on cats. This veterinary medicinal product is extremely poisonous to cats and could be fatal due to the unique physiology of cats which is unable to metabolise certain compounds including permethrin. To prevent cats from being accidentally exposed to the veterinary medicinal product, keep treated dogs away from cats after treatment until the application site is dry. It is important to ensure that cats do not groom the site of application on a dog, which has been treated with this veterinary medicinal product. Seek veterinary advice immediately if this occurs. Do not use on rabbits and cats as adverse reactions and even death can occur In case of accidental dermal exposure, wash the cat with shampoo or soap, and seek veterinary advice rapidly.
    Sources: VMD SPC · VMD
  • Warning (Dog)
    In the absence of available data the veterinary medicinal product should not be used on puppies of less than 7 weeks of age or 1.5 kg of weight. The safety of the product has not been established in dogs younger than 12 weeks of age or in dogs weighing less than 1.5 kg.
    Sources: VMD SPC · VMD
  • Caution (Dog)
    Can be used during pregnancy and lactation. The safety of the veterinary medicinal product has not been established in dogs during pregnancy, lactation or in animals intended for breeding. Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have shown evidence of foetotoxic effects. Use only according to the benefit-risk assessment by the responsible veterinarian. The safety of the veterinary medicinal product has not been established during pregnancy and lactation in bitches. Use in pregnancy and lactation only in accordance with professional veterinary advice and a benefit/risk assessment.
    Sources: VMD SPC · VMD
  • Caution (Dog)
    Can be used during pregnancy and lactation. Use only according to the benefit-risk assessment by the responsible veterinarian.
    Sources: VMD SPC · VMD

All of this shows in vetman as you prescribe

The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.