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Stronghold Plus

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Selamectin + Sarolaner · Zoetis

3 forms: spot-on. In force in Georgia: 3 of 3 (veterinary register).

Forms and doses3 of 3 in force in Georgia

The dose from the product's label, by species and weight. Check the label of the pack you use.

Choose species and weight; the matching row will be highlighted.
Form Species Weight Dose Frequency Georgia
15 mg/2.5 mg, Spot-on · Cat 1.25–2.5 kg Cat 1.25–2.5 kg 1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Use of this veterinary medicinal product is indicated in cats aged at least 8 weeks old and weighing at least 1.25 kg bodyweight. Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age). selamectin is considered safe for use in breeding, pregnant and lactating cats
 · monthly		 monthly Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 15მგ/2.5მგ დასაწვეთებელი ხსნარი კატებისთვის ≤ 2.5კგ
№ 130-11
Verified on: 15 Oct 2026
15 mg/2.5 mg, Spot-on · Dog Any weight Dog Any weight No dose for this species
This product is labelled only for cats; no canine dose is established.
 - Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 15მგ/2.5მგ დასაწვეთებელი ხსნარი კატებისთვის ≤ 2.5კგ
№ 130-11
Verified on: 15 Oct 2026
Details: pack, label wording, sources, registration

Stronghold Plus 15 mg/2.5 mg, Spot-on

selamectin 15 mg + sarolaner 2.5 mg, spot-on solution for cats up to 2.5 kg
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Cat
8.2/10
Very good
vetman assessment

Stronghold Plus

15 mg/2.5 mg, selamectin 15 mg + sarolaner 2.5 mg, spot-on solution for cats up to 2.5 kg
Assessed clinical scopeCat · Full labelled feline mixed-parasite scope when tick control and at least one other labelled target are required together: fleas, ticks, heartworm prevention, roundworms, hookworms, lice, ear mites and notoedric mange · On the skin
Care settingVeterinary-selected monthly or single-dose integrated parasite control based on the exact indication
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 130-11 · Verified on 15 Oct 2026

A strong monthly feline endectoparasite option when tick control and another labelled target coincide; avoid the extra sarolaner component when tick treatment is not needed.

Regulatory and scientific credibility9.0/10

All three exact strengths have current transparent official SPCs and active Georgian veterinary registration, supported by multiple indication-specific field and controlled trials.

Clinical efficacy8.5/10

Field and controlled studies support strong monthly flea and tick control and high efficacy for labelled mites and other selamectin-sensitive parasites; the fixed combination is justified only when tick control and another target are needed together.

Safety and tolerability7.0/10

Usually well tolerated, but do not use in cats with concurrent disease or in debilitated, underweight animals; reproduction lacks combination safety data and rare neurologic reactions are possible with the isoxazoline component.

Clinical practicality8.5/10

A single colour-coded weight-band pipette is simple and monthly scheduling is clear, but it must reach dry skin, licking must be prevented and single-dose versus monthly indications must not be confused.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in cats with concurrent disease or in debilitated and underweight cats, or in hypersensitivity to either active substance or an excipient.
  • Use the fixed combination only when tick control and at least one other labelled parasite target are indicated at the same time.
  • Use only from 8 weeks of age and at least 1.25 kg; apply the exact pipette to dry skin at the neck and never into the ear canal or by mouth.
  • Combination safety is not established in breeding, pregnant or lactating cats; use only after an individual benefit-risk assessment.
Assessment sources
  1. VMD SPC 20252025
  2. Stronghold Plus field studies2017
  3. Stronghold Plus notoedres RCT2025
  4. Stronghold Plus tick RCT2017
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Selamectin15 mg Sarolaner2.5 mg
Formulation Type
Spot-on
Administration route
On the skin
Manufacturer
Zoetis · United States
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 15მგ/2.5მგ დასაწვეთებელი ხსნარი კატებისთვის ≤ 2.5კგ
№ 130-11
Verified on: 15 Oct 2026
 EU Yes, veterinary
Verified on: 15 Oct 2026
 UK Yes, veterinary
Verified on: 15 Oct 2026
 US Yes, veterinary
№ NADA 141-502
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Use of this veterinary medicinal product is indicated in cats aged at least 8 weeks old and weighing at least 1.25 kg bodyweight. Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age). selamectin is considered safe for use in breeding, pregnant and lactating cats
 Cat 1.25–2.5 kg On the skin monthly Product label (SPC)
No dose for this species
This product is labelled only for cats; no canine dose is established.
 Dog Any weight On the skin - Product label (SPC)
30 mg/5 mg, Spot-on · Cat 2.5–5 kg Cat 2.5–5 kg 1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
 · monthly		 monthly Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 30მგ/5მგ დასაწვეთებელი ხსნარი კატებისთვის > 2.5–5 კგ
№ 128-11
Verified on: 15 Oct 2026
30 mg/5 mg, Spot-on · Dog Any weight Dog Any weight No dose for this species
This product is labelled only for cats; no canine dose is established.
 - Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 30მგ/5მგ დასაწვეთებელი ხსნარი კატებისთვის > 2.5–5 კგ
№ 128-11
Verified on: 15 Oct 2026
Details: pack, label wording, sources, registration

Stronghold Plus 30 mg/5 mg, Spot-on

selamectin 30 mg + sarolaner 5 mg, spot-on solution for cats >2.5-5 kg
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Cat
8.2/10
Very good
vetman assessment

Stronghold Plus

30 mg/5 mg, selamectin 30 mg + sarolaner 5 mg, spot-on solution for cats >2.5-5 kg
Assessed clinical scopeCat · Full labelled feline mixed-parasite scope when tick control and at least one other labelled target are required together: fleas, ticks, heartworm prevention, roundworms, hookworms, lice, ear mites and notoedric mange · On the skin
Care settingVeterinary-selected monthly or single-dose integrated parasite control based on the exact indication
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 128-11 · Verified on 15 Oct 2026

A strong monthly feline endectoparasite option when tick control and another labelled target coincide; avoid the extra sarolaner component when tick treatment is not needed.

Regulatory and scientific credibility9.0/10

All three exact strengths have current transparent official SPCs and active Georgian veterinary registration, supported by multiple indication-specific field and controlled trials.

Clinical efficacy8.5/10

Field and controlled studies support strong monthly flea and tick control and high efficacy for labelled mites and other selamectin-sensitive parasites; the fixed combination is justified only when tick control and another target are needed together.

Safety and tolerability7.0/10

Usually well tolerated, but do not use in cats with concurrent disease or in debilitated, underweight animals; reproduction lacks combination safety data and rare neurologic reactions are possible with the isoxazoline component.

Clinical practicality8.5/10

A single colour-coded weight-band pipette is simple and monthly scheduling is clear, but it must reach dry skin, licking must be prevented and single-dose versus monthly indications must not be confused.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in cats with concurrent disease or in debilitated and underweight cats, or in hypersensitivity to either active substance or an excipient.
  • Use the fixed combination only when tick control and at least one other labelled parasite target are indicated at the same time.
  • Use only from 8 weeks of age and at least 1.25 kg; apply the exact pipette to dry skin at the neck and never into the ear canal or by mouth.
  • Combination safety is not established in breeding, pregnant or lactating cats; use only after an individual benefit-risk assessment.
Assessment sources
  1. VMD SPC 20252025
  2. Stronghold Plus field studies2017
  3. Stronghold Plus notoedres RCT2025
  4. Stronghold Plus tick RCT2017
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Selamectin30 mg Sarolaner5 mg
Formulation Type
Spot-on
Administration route
On the skin
Manufacturer
Zoetis · United States
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 30მგ/5მგ დასაწვეთებელი ხსნარი კატებისთვის > 2.5–5 კგ
№ 128-11
Verified on: 15 Oct 2026
 EU Yes, veterinary
Verified on: 15 Oct 2026
 UK Yes, veterinary
Verified on: 15 Oct 2026
 US Yes, veterinary
№ NADA 141-502
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
 Cat 2.5–5 kg On the skin monthly Product label (SPC)
No dose for this species
This product is labelled only for cats; no canine dose is established.
 Dog Any weight On the skin - Product label (SPC)
60 mg/10 mg, Spot-on · Cat 5–10 kg Cat 5–10 kg 1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
 · monthly		 monthly Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 60მგ/10მგ დასაწვეთებელი ხსნარი კატებისთვის > 5–10კგ
№ 127-11
Verified on: 15 Oct 2026
60 mg/10 mg, Spot-on · Dog Any weight Dog Any weight No dose for this species
This product is labelled only for cats; no canine dose is established.
 - Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 60მგ/10მგ დასაწვეთებელი ხსნარი კატებისთვის > 5–10კგ
№ 127-11
Verified on: 15 Oct 2026
Details: pack, label wording, sources, registration

Stronghold Plus 60 mg/10 mg, Spot-on

selamectin 60 mg + sarolaner 10 mg, spot-on solution for cats >5-10 kg
vetman assessment
vetman’s 10-point assessment brings together a product’s regulatory credibility, clinical efficacy, safety and practicality. Cost-effectiveness is assessed only when reliable data are available. It is informational and does not replace a veterinarian’s clinical judgment for an individual patient.
Cat
8.2/10
Very good
vetman assessment

Stronghold Plus

60 mg/10 mg, selamectin 60 mg + sarolaner 10 mg, spot-on solution for cats >5-10 kg
Assessed clinical scopeCat · Full labelled feline mixed-parasite scope when tick control and at least one other labelled target are required together: fleas, ticks, heartworm prevention, roundworms, hookworms, lice, ear mites and notoedric mange · On the skin
Care settingVeterinary-selected monthly or single-dose integrated parasite control based on the exact indication
vetman score 8.2/10 Very good
Evidence confidence: High Georgia: Yes, veterinary · № 127-11 · Verified on 15 Oct 2026

A strong monthly feline endectoparasite option when tick control and another labelled target coincide; avoid the extra sarolaner component when tick treatment is not needed.

Regulatory and scientific credibility9.0/10

All three exact strengths have current transparent official SPCs and active Georgian veterinary registration, supported by multiple indication-specific field and controlled trials.

Clinical efficacy8.5/10

Field and controlled studies support strong monthly flea and tick control and high efficacy for labelled mites and other selamectin-sensitive parasites; the fixed combination is justified only when tick control and another target are needed together.

Safety and tolerability7.0/10

Usually well tolerated, but do not use in cats with concurrent disease or in debilitated, underweight animals; reproduction lacks combination safety data and rare neurologic reactions are possible with the isoxazoline component.

Clinical practicality8.5/10

A single colour-coded weight-band pipette is simple and monthly scheduling is clear, but it must reach dry skin, licking must be prevented and single-dose versus monthly indications must not be confused.

Full-course cost-effectiveness-

Price was not assessed and is excluded from the overall score.

Important safety and use flags

  • Do not use in cats with concurrent disease or in debilitated and underweight cats, or in hypersensitivity to either active substance or an excipient.
  • Use the fixed combination only when tick control and at least one other labelled parasite target are indicated at the same time.
  • Use only from 8 weeks of age and at least 1.25 kg; apply the exact pipette to dry skin at the neck and never into the ear canal or by mouth.
  • Combination safety is not established in breeding, pregnant or lactating cats; use only after an individual benefit-risk assessment.
Assessment sources
  1. VMD SPC 20252025
  2. Stronghold Plus field studies2017
  3. Stronghold Plus notoedres RCT2025
  4. Stronghold Plus tick RCT2017
Assessed: 21 Oct 2026The overall score uses 25/25/25/15/10 weights. An unassessed price is excluded and the remaining weights are proportionally renormalised.
Composition / strength
Selamectin60 mg Sarolaner10 mg
Formulation Type
Spot-on
Administration route
On the skin
Manufacturer
Zoetis · United States
Manufacturer (register)
Zoetis Inc., United States
Manufacturer and country as in the veterinary medicines register (National Food Agency), row 834, 19 Oct 2026.
Source: NFA veterinary medicines register ↗
Registration
Georgia Yes, veterinary
Veterinary (National Food Agency)
In the register: სტრონგჰოლდ პლუსი 60მგ/10მგ დასაწვეთებელი ხსნარი კატებისთვის > 5–10კგ
№ 127-11
Verified on: 15 Oct 2026
 EU Yes, veterinary
Verified on: 15 Oct 2026
 UK Yes, veterinary
Verified on: 15 Oct 2026
 US Yes, veterinary
№ NADA 141-502
Verified on: 15 Oct 2026
Controlled in Georgia
No
Checked against the narcotics law, Annex 1, lists I-IV, and Order No. 22/n.
Verified on: 16 Oct 2026
DoseSpeciesWeightRouteFrequencySource
1 pipette
corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
 Cat 5–10 kg On the skin monthly Product label (SPC)
No dose for this species
This product is labelled only for cats; no canine dose is established.
 Dog Any weight On the skin - Product label (SPC)
Active substance doses, with sources
Active substance Selamectin
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
6 mg/kg Dog, Cat Maintenance On the skin monthly
VMD SPC 2025
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Stronghold 15 mg spot-on solution for cats and dogs <= 2.5 kg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2025
Active substance Sarolaner
Dose calculatorCalculates the active-substance amount; it is not a prescription.
PatientSpecies and weight will be filled in automatically in other calculators.
Selected dose
Dose Species Indication Route Frequency Source
2–4 mg/kg Dog Maintenance By mouth monthly
VMD SPC 2024
Official product label (SPC), VMD, UK
Approved by the UK Veterinary Medicines Directorate (VMD) as part of the product's authorisation. It applies to that product as authorised there.
Simparica 5 mg chewable tablets for dogs 1.3-2.5 kg - Summary of Product Characteristics
UK Veterinary Medicines Directorate, 2024

Known Contraindications

  • Critical Sarolaner
    Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
    Sources: VMD SPC · VMD
  • Warning Sarolaner (Dog)
    The safety of the veterinary medicinal product has not been established during pregnancy and lactation or in animals intended for breeding. Pregnancy and lactation: The use in these animals is not recommended. Fertility: The use in breeding animals is not recommended. The safe use of SIMPARICA has not been evaluated in breeding, pregnant, or lactating dogs.
    Sources: VMD SPC · VMD · FDA
  • Warning Sarolaner (Dog)
    Pregnancy and lactation: The use in these animals is not recommended.
    Sources: VMD SPC · VMD
  • Warning Sarolaner (Dog)
    In the absence of available data, treatment of puppies less than 8 weeks of age and/or dogs less than 1.3 kg bodyweight should be based on a benefit-risk assessment by the responsible veterinarian. less than 1.25 kg
    Sources: VMD SPC · VMD
  • Warning Sarolaner (Dog)
    The minimum age for sarolaner depends on the product label. Some labels permit use from 8 weeks, while the US Simparica label restricts use to dogs at least 6 months old because younger puppies developed neurological signs at high multiples of the dose. Follow the selected product’s label.
    Sources: VMD SPC · VMD · FDA
  • Caution Sarolaner (Dog)
    Sarolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. mild tremors convulsions
    Sources: VMD SPC · VMD · FDA
  • Critical Selamectin
    Do not use in animals under 6 weeks of age.
    Sources: VMD SPC · VMD
  • Critical Selamectin
    Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
    Sources: VMD SPC · VMD
  • Warning Selamectin (Cat)
    Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
    Sources: VMD SPC · VMD

Products are connected by name, active ingredients, or therapeutic group. They are not direct substitutes for one another.

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This reference is still growing. Missing a product? Let us know. · Report an error or request an addition · Updated: 16 Oct 2026

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The dose for the patient's weight, registration in Georgia and controlled status, right on the prescription.

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